On ne peut progresser sans se tromper. Comment dès lors inviter les étudiants à ne plus craindre l’erreur mais à la voir comme une opportunité d’acquérir de nouvelles compétences ? Exemple à travers un dispositif d’apprentissage par l’action.

New Brief Communication: "A CRISPR-based sequence proximity binding protein labelling system for scanning upstream regulatory proteins" rdcu.be/eZLUP CRISPR-based proximity labelling system to profile DNA-binding proteins such as PIF4 transcription factor .

Enhancing apple disease resistance using magnetic nanoparticles carrying artificial miRNAs that suppress a tRNA-derived small RNA targeting a disease-resistant gene #research #PlantCommunications cell.com/plant-commun...

Our new article is now online on @natplants.nature.com! ✨ We identified and characterised AvrPm4 and SvrPm4, a pair of powdery mildew effectors controlling avirulence on the wheat kinase fusion resistance protein Pm4 🌾 check it out ➡️ www.nature.com/articles/s41...

New preprint 👉Doudna x Bryant x Jacobsen x Savage collaboration! Work led by @zehanzhou.bsky.social, I. Saffarian-Deemyad, @honglue.bsky.social, T. Weiss We dissect how stepwise DNA unwinding gates TnpB genome editing, revealing how unwound DNA states enhance cleavage www.biorxiv.org/content/10.6...

A (belated!) highlight from an excellent collaboration with @dunhamlab.bsky.social and #HouLabTJU. In this Nat Commun paper, we combine smFRET and cryo-EM to show how the tRNA modification m¹G37 stabilizes the reading frame—and what happens when it’s missing.

very unusual - a tRNA regulated anion channel

✨New preprint! 🧵1/4 Excited to share our work on AI-guided design of minimal RNA-guided nucleases. Amazing work by @petrskopintsev.bsky.social @isabelesain.bsky.social @evandeturk.bsky.social et al! Multi-lab collaboration @banfieldlab.bsky.social @jhdcate.bsky.social @jacobsenucla.bsky.social🧬 🔗👇

Phages are full of genes of unknown function that are likely adaptive in specific conditions. New preprint: Phage TnSeq identifies essential genes rapidly and knocks all non-essentials. We would like to send a pool of phiKZ mutants to anyone wanting it! Reach out tinyurl.com/bdcfrejh

Ethylene modulates cell wall mechanics for root responses to compaction www.nature.com/articles/s41...

Timing of transcription controls the selective translation of newly synthesized mRNAs during acute environmental stress

We can learn a lot about our own biology just by figuring out how viruses hack our systems! Avoid mRNA circularization to scape the codon usage trap set by the host. www.nature.com/articles/s41...

Oh Wow! Cell wall patterning regulates plant stem cell dynamics | Science www.science.org/doi/10.1126/...

Preprint: Systematic discovery of TIR-based immune signaling systems in bacteria Conservation of TIR-derived signals accross the tree of life! We found bacterial TIR immune systems that signal via canonical cADPR (like in humans) and 2'cADPR (a plant immune signal). Documented 11 Thoeris types

Gut mucin fucosylation dictates the entry of botulinum toxin complexes www.nature.com/articles/s41...

IN BRIEF: Tailored translation: Local tRNA activation to match protein composition needs (Laura Arribas-Hernández) doi.org/10.1093/plce... #PlantScience @aspbofficial

Miam!

Recurrent evolution of selfishness from an essential tRNA synthetase in Caenorhabditis tropicalis www.nature.com/articles/s41...

🌱 EXPERT VIEW 🌱 In all land plants, small secreted peptides belonging to the CLE family move from cell to cell and activate their cognate receptors to control a plethora of developmental processes - Cornelis & Hazak 🔗 doi.org/10.1093/jxb/... #PlantScience 🧪 @hazaklab.bsky.social

Congratulations to @jeremywyman.bsky.social et al 2025 for the publication of their Oxroadia paper! And thanks for bringing me onboard to do some restorations of this relative of Lepidodendron and Isoëtes from the Carboniferous of Scotland. academic.oup.com/aob/advance-... #FossilFriday #paleobotany

A team led by @kit.edu and with significant participation from @leibnizipk.bsky.social has succeeded for the first time in specifically altering the chromosome number of Arabidopsis using CRISPR Cas - without adversely affecting plant growth. www.science.org/doi/10.1126/...

Two M. tuberculosis RelE toxins don’t cut mRNA, they slice 16S rRNA itself, shutting down translation in a totally unexpected way, new study reveals. A big leap in understanding TB’s survival tricks and new angles for therapies. 📖 shorturl.at/Z8MVX ✍️ @genevauxpierre.bsky.social & coll. #MicroSky

This work is now officially published @natsmb.nature.com with some fun new analyses included in the revised version. Congratulations to all the authors! @connyyu.bsky.social @rappsilber.bsky.social @lrsinn.bsky.social @fjoreilly.bsky.social www.nature.com/articles/s41...

This is a remarkable study describing a new fungal species in a 407 million year old plant - Rugososporomyces lavoisierae Strullu-Derrien and Schornack sp. nov - using some amazing technology. Worth a read 👇

We are looking for a PhD student to work on an exciting plastid endosymbiosis in microbial eukaryotes. This position involves sampling, exciting microscopy such as CARDFISH, ExM and FIBSEM, single-cell transcriptomics and more. #protistsonsky 1/2

Our nuclease-protease story is out! We explored a fascinating case of coevolution and modularity in prokaryotic immune systems: www.science.org/doi/10.1126/... Thanks to wonderful coauthors/collaborators/friends, the whole @doudna-lab.bsky.social and everyone at @innovativegenomics.bsky.social

Beyond the niche - unlocking the full potential of synthetic riboswitches doi.org/10.1038/s414...

An Asgard archaeon with internal membrane compartments Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors! www.biorxiv.org/content/10.1...

The worst thing about the book is that it creates the impression that this hypercompetitive, no respect for rules or others, approach to science is normal or desirable. 21/41

Watson was an opportunist. He took advantage of Crick’s command of crystallography and managed to get access to Franklin’s experimental data including the famous Photography 51 which reveal a simple cross-like diffraction pattern of DNA in high humidity. 15/41

Yes, some people's legacies are complicated. For example, Watson. After all, though he was racist, don't forget his other traits. For example, he was also sexist. And also anti-semitic. And a data / idea thief. So let's not forget all the different facets.

When people celebrate the individual genius of folks in science, they should also mourn the collective loss of genius of folks who were actively discouraged or disadvantaged from a career in science because of the same person(s)

Guillaume Hummel, David Pflieger, Alexandre Berr, Laurence Drouard: From the RNA world to land plants: Evolutionary insights from tRNA genes https://arxiv.org/abs/2511.01943 https://arxiv.org/pdf/2511.01943 https://arxiv.org/html/2511.01943

Thrilled to share our new preprint on the evolution of transfer RNA (tRNA) genes in photosynthetic organisms, together with David Pflieger, Alexandre Berr, and Laurence Drouard! #PlantGenomics #Evolution #tRNA @ibmp-cnrs.bsky.social arxiv.org/abs/2511.01943

How sodium gets sequestered in the vacuoles of salinized plants? #opinion #MolecularPlant cell.com/molecular-pl...

Excited to share my first PhD student’s @biorxivpreprint.bsky.social! Tracking 5 dyes simultaneously Kavan Gor @embl.org tracks nascent #RNA folding during #ribosome assembly to correlate structural with functional information on single RNA molecules! Check it out! www.biorxiv.org/content/10.1...

Cool work by @microberna.bsky.social & Kai Papenfort, presenting the first RNA-RNA map in C. crescentus using RIL-seq, revealing an RNA sponge that controls the transition from nutrient abundance to starvation; new insights into RNA networks and stress responses! #RNA www.nature.com/articles/s41...

Plant cell wall signaling is indeed a very dynamic process 🌱 You can read what our very own Sebastian Wolf says about pectin in this news feature 👇

1/ Excited to share our new study with @brumbaugh-lab.bsky.social, out in @natbiotech.nature.com! P-bodies selectively sequester RNAs encoding cell fate regulators, often from the preceding developmental stage. Releasing these RNAs can drive changes in cell identity. 🧵 www.nature.com/articles/s41...

Been working on a really strange retron bacterial immune system, here's the preprint: www.biorxiv.org/content/10.1... Type VI retrons are unlike any other. Phage infection triggers reverse transcription of a DNA fragment that activates translation of a toxin to kill the infected cell.

Here, we show that the unique regulatory landscape of ecDNA enables an ancient LINE to resurrect and act as an enhancer of Myc. This was so fun with @katerinakraft.bsky.social and @mattjones.bsky.social and others. www.nature.com/articles/s41...

#Intercropping & #CropRotation are ancient #agricultural practices that increase yield & #DiseaseResistance in #crops. This Essay discusses the role of plant-derived metabolites & microbes in these systems and how they can contribute to #SustainableAgriculture @plosbiology.org 🧪 plos.io/4op7k6W

Our paper on the evolution (duplicated) gene expression divergence in spatially resolved plant transcriptomes is now out @theplantcell.bsky.social w/ @yvdp.bsky.social #PlantSci #Evolution academic.oup.com/plcell/advan...

1/10 Genome maintenance by telomerase is a fundamental process in nearly all eukaryotes. But where does it come from? Today, we report the discovery of telomerase homologs in a family of antiviral RTs, revealing an unexpected evolutionary origin in bacteria. www.biorxiv.org/content/10.1...

New Article: "Pan-centromere landscape and dynamic evolution in Brassica plants" rdcu.be/eLtOL Pan-centromere landscape and evolutionary dynamics in Brassica. T2T genome assemblies of multiple morphotypes shedding light on centromere evolution during domestication.

The role of post-translational modifications in the dynamics of cytoplasmic biomolecular condensates in #plants A #ResearchReview by Legoux et al. 👇 📖 nph.onlinelibrary.wiley.com/doi/10.1111/... #LatestIssue #PlantScience

🚀 New preprint! We used a human cell-free translation screen (~28 000 compounds) to discover NT-2, a #Fusarium -derived #mycotoxin that blocks human ribosomes. #Cryo-EM at 1.72 Å reveals a link between chemical inhibition and ribosome dormancy. www.biorxiv.org/content/10.1...

Game changer for cell-based plant genetics: the labs of Caixia Gao & Jin-Long Qiu have developed very efficient self-replicating vectors and they just published a very nice proof-of-concept paper. #plantscience www.science.org/doi/10.1126/...