📢 AI in Radiation Oncology — 15 Jan 2026 📍 Genolier, Switzerland | Supported by ESTRO A one-day deep dive into AI for contouring, imaging, radiomics & clinical integration. 🎥: bit.ly/4pyIDGe ℹ️: bit.ly/4pARCGQ #Radonc #AIinHealthcare #MedicalAI #Radiotherapy

We are recruiting an EU Projects Officer to join our team in Brussels. ✍️ 📍 Brussels, Belgium 🕒 Full-time, permanent contract 🗓 Application deadline: 11 January 2026 Full details are available in the job description at: www.europeancancer.org/content/eu-p...

#ESMODailyReporter: Jon Lim, MRCP PhD discusses the use of single-cell spatial transcriptomics and proteomic profiling to dissect why #immunotherapy works in some tumours but not others, highlighting neoadjuvant studies at #ESMOImmuno25 #ImmunoOncology ➡️ https://ow.ly/kwgt50XGX4M#ESMODailyReporter

A review on pseudogene-derived lncRNAs signaling in cancer stem cell regulation, their classification & functions, and their dysregulation in CSC development, highlighting their potential as #Biomarkers. @TehUofMed #OpenAccess: doi.org/10.1016/j.ge...

This review highlights the critical role of the #ImmuneMicroenvironment in #ADPKD progression, detailing how immune cells, #inflammation, complement activation, and immune checkpoints like PD-1/PD-L1 contribute to #CystGrowth and #fibrosis. #OpenAccess: doi.org/10.1016/j.ge...

A review on the #AntiTumor mechanisms of high-dose #VitaminC, detailing preclinical & clinical studies investigating its #AntiCancer role, advancements in high-dose vitamin C therapy for #Cancer treatment, and directions for future research. #OpenAccess: doi.org/10.1016/j.ge...

Researchers highlight #oncolytic #HerpesSimplexVirus (HSV-1) viruses as promising #CancerImmunotherapies, detailing advances in #glycoprotein retargeting, discussing molecular entry mechanisms, clinical successes, and future challenges. #OpenAccess: doi.org/10.1016/j.ge...

This review discusses #MitochondrialDysfunction in #ParkinsonsDisease (PD), its molecular mechanisms, and the role of mitochondrial dysfunction in aging microglia and astrocytes in PD #Pathogenesis, highlighting future research directions. #OpenAccess: doi.org/10.1016/j.ge...

Our new podcast episode explores a fascinating research paper on the impact of high-fat diets on tumour growth, by Dr Hannah Prendeville and Dr Britta Kunkemoeller. Listen or read the transcript:

🙌 To everyone who powered ESMO Asia 2025—thank you! From pioneering science to global collaboration, your contributions shaped an inspiring congress. 📅 See you next year in Singapore, 4–6 Dec 2026! #esmomeetings #ESMOAsia25 🔗 buff.ly/J1q4Zzv

Join a global community of arrhythmia care experts and peers at #EHRA26 – in Paris or online – to spark new connections and experience a Scientific Programme highlighting the latest breakthroughs, including trailblazing late-breaking trials. Register by 12 Feb to save👉https://ow.ly/7HWb50XG7g1

This review outlines how #ferroptosis—driven by #GPX4 regulation, #IronMetabolism, and #LipidPeroxidation—offers a strategy to reverse #DrugResistance in digestive system #cancers, highlighting emerging ferroptosis-inducing therapeutic approaches. #OpenAccess: doi.org/10.1016/j.ge...

2026 Medical Oncology In-Training Exam registration is open! This proctored, Internet-based exam (Feb 24 & 25) is a great way to track progress w/ teaching points & performance percentages across key domains. Discounts available. Learn more & register: brnw.ch/21wYaYT

Data presented at ASH suggest that the CRISPR therapy could provide a one-time functional cure in children as young as 5 years old, researchers said.

Be part of the Heart Team in action at #ACVC26 for the opportunity to collaborate and connect with you community. Register by 20 January to save: https://bit.ly/48urmq9#ACVC26 📍 Lisbon | 20-21 March #ACVC_ESC

SET–PP2A axis driven increased levels of both H2AX and γH2AX in #Glioma #StemCells (GSCs) maintain GSC self-renewal and #Tumorigenic capacity, highlighting it as a potential #TherapeuticTarget to disrupt GSC-driven #Tumor growth. #medsky #OpenAccess: doi.org/10.1016/j.ge...

Insights from regenerative medicine a field with the potential to transform how we treat injury, disease & organ failure. Here is a selection of recent findings published in Genes & Diseases and what they could mean for patients, clinicians and researchers. www.keaipublishing.com/en/journals/...

#CXCR4, highly expressed in #aldosterone-producing #adenomas, co-localizes with #CYP11B2 & suppresses aldosterone synthesis by inhibiting CYP11B2 transcription, suggesting CXCR4 acts as a compensatory regulator in aldosterone-producing lesions. #OpenAccess: doi.org/10.1016/j.ge...

Reviewing the role of peripheral nerves in #SolidTumors, with insights into the prevalence & clinical impact of nerve–tumor interactions, their underlying mechanisms, research advancements and therapeutic potential. @pku1898.bsky.social #OpenAccess: doi.org/10.1016/j.ge...

Obesity-associated fibroblasts reshape the #TME across #cancers, identify the TS.FIBRO.OBESITY.SIG signature linked to #ECM remodeling, #ImmuneSuppression and #TherapyResistance, and highlight key genes that may guide prognosis and treatment. #OpenAccess: doi.org/10.1016/j.ge...

Groundbreaking study paves the way for #noninvasive #BladderCancerScreening tools that enhance patient comfort and improve outcomes. #BladderCancer #UrineTest #CellFreeDNA

Improving representation in clinical trials is vital to understanding cancer. Researchers at a recent conference shared new approaches to more people with cancer. Read more in Cancer Today. buff.ly/Sc1pLFT

#ESMOAsia25: Studies in cancer of unknown primary (#CUP) highlight the need to perform routine comprehensive #GenomicProfiling and then provide access to the appropriate #TargetedTherapy. Find out more in the #ESMODailyReporter ➡️https://ow.ly/sK6H50XF5t7#ESMOAsia25#CUP)

IFN-λs suppress autoreactive Th1 & Th17 cell responses, promote #Treg expansion, and regulate NLRP1/NLRP3 signaling to preserve BRB integrity and attenuate #OcularInflammation in experimental #Autoimmune #uveitis. #medsky #OpenAccess: doi.org/10.1016/j.ge...

This review explores the action mechanism of PARPi, the mechanisms underlying #PARPi resistance in cancers, and summarizes the strategies to overcome PARPi resistance, to extend PARPi applications and improve patient outcomes. #medsky #OpenAccess: doi.org/10.1016/j.ge...

This review examines #GPR126's expression, #ligandreceptor interactions, signaling, and roles in development/diseases, highlighting small molecule, #peptide, and #monobody modulators as promising #aGPCRs-targeted therapies. #OpenAccess: doi.org/10.1016/j.ge...

Reviewing the tissue distribution, transfection rates and #Immunogenicity of recombinant adeno-associated virus serotype 8 (#AAV8) in gene therapy, with insights into the applications and challenges of using AAV8 as a vector. #OpenAccess: doi.org/10.1016/j.ge...

Submit an abstract by December 8 for the AACR Special Conference on RAS Oncogenesis and Therapeutics (March 5-8, 2026; Los Angeles), chaired by Andrew J. Aguirre, Channing J. Der, David S. Hong, and Kevan M. Shokat. Learn more: buff.ly/KSYsLWC #AACRras26

A new review highlights five ways #microplastics can trigger #inflammation and #BrainDamage. #Neuroinflammation #NeurodegenerativeDiseases #Alzheimers #Parkinsons

Last Chance! Nominate your mentor for the @conquercancer.bsky.social Women Who Conquer Cancer Mentorship Award. Deadline is December 12th. Don't miss this final call! wwcc.secure-platform.com/a

This review highlights #CRISPRCas9 as a precise #GeneEditing tool with therapeutic applications across #cancers, and acquired diseases, discussing #ClinicalTrials, off‑target challenges, and advances in #viral and #NonViralDelivery systems. #OpenAccess: doi.org/10.1016/j.ge...

A review on m6A methylation regulation & its biological functions in the #ImmuneSystem, detailing its critical role in the #Pathogenesis of #AutoimmuneDiseases, identifying potential #Biomarkers & targets for their prevention & treatment. #OpenAccess: doi.org/10.1016/j.ge...

Researchers elucidate how #Hypoxiainduciblefactor1α drives #tumor progression in solid and hematological malignancies by regulating proliferation, #angiogenesis, metabolism, immunity, and therapy resistance in #hypoxic #microenvironments. #OpenAccess: doi.org/10.1016/j.ge...

Dr. Sumanta Pal of @cityofhope.bsky.social & @lymphomadoc.bsky.social of @mdanderson.bsky.social discuss two of the major challenges facing oncologists in 2026 on the latest episode of the #ASCODailyNews Podcast: brnw.ch/21wY5Tt

📣 Welcome to ESMO Asia 2025! Together we bring dedication, expertise and shared purpose to one of the most important oncology meetings in the Asia-Pacific region. Let’s move forward as one. #ESMOAsia25 #esmomeetings 🔗 buff.ly/z5gybDc

In the #ESMODailyReporter, Eileen Yi Ling Poon discusses addressing the medical and psychosocial needs of adolescents and young adults (#AYA) w/ cancer, providing individualised treatment, targeted emotional support and age-appropriate information: https://ow.ly/O94S50XCBee#ESMODailyReporter#AYA)#ESMOAsia25

This review explains how tumor cell heterogeneity, including resistant and tolerant subpopulations and quiescent states, drives #TherapyAdaptation and cancer survival, highlighting mechanisms that may help prevent recurrence. #cancer #medsky #OpenAccess: doi.org/10.1016/j.ge...

Reviewing the structure, regulation, and function of RRM2 and its inhibitors, its critical role in promoting tumor malignancy, #TumorImmunity, #TherapyResistance & the #TumorMicroenvironment, with insights into RRM2-targeted therapies. #medsky #OpenAccess: doi.org/10.1016/j.ge...

This review highlights the CD47‑SIRPα axis as a key #ImmuneCheckpoint in #lymphoma, detailing current therapeutic strategies, including #FcFusionProteins and #peptides, and underscores their potential in treating Hodgkin and #NonHodgkinlymphomas. #OpenAccess: doi.org/10.1016/j.ge...

📌The #ThinkNENs program is designed to empower PCPs with the knowledge to recognize NENs and refer NEN patients earlier. • Free, online & CME-accredited • Available in 7 languages • Endorsed by top NEN societies ✅Start today: incalliance.org/think-nens/ #LetsTalkAboutNETs

🚨 Submit your abstract for #ELCC26! Share your research and help shape the future of #LungCancer care. ⏰ Deadline: 13 January 2026, Copenhagen & Online | 25–28 March 2026 🔗 https://ow.ly/E4N350XAv5k

The Trainee Track is available in the #EAPCI26 programme Built for growth, it delivers expert-led theory, practical guidance, tools & hands-on training w/ an EAPCI-certified completion to support your next step. Explore the programme & register by 8 Dec to save https://bit.ly/3K3hHin#EAPCI26 #EAPCI

This review outlines how EV-ncRNAs drive #PreMetastaticNiche formation by shaping #immunosuppression, #VascularRemodeling, #inflammation, metabolism, and #fibroblast activation across #cancers, highlighting their promise as #biomarkers. #OpenAccess: doi.org/10.1016/j.ge...

Trontinemab, designed to reach the brain better than gantenerumab, led to amyloid negativity in 92 percent of patients at the highest dose in a Phase Ib/IIa trial.

Submit an abstract by December 4 for the AACR Special Conference on Innovations in Kidney Cancer Research (March 13-16, 2026; Philadelphia), chaired by Eric Jonasch, M. Celeste Simon, Samra Turajlic, and Qing Zhang. Learn more: buff.ly/IoqbeGk #AACRkidney26 @turajliclab.bsky.social

New episode! 🎧 Host @stephenvliu.bsky.social talks with Prof. Li Zhang and Dr. Elaine Shum about how ADCs are reshaping treatment for EGFR-mutant NSCLC, from new approvals to next-gen agents on the horizon. Listen here: bit.ly/3XyFycL #LungCancer #NSCLC #EGFR #ADCs #CancerResearch

This review highlights how #MesenchymalStemCells exert therapeutic effects through #ParacrineSignaling—releasing #GrowthFactors, #cytokines, #chemokines, #ExtracellularMatrix components, & extracellular vesicles shaped by the #microenvironment. #OpenAccess: doi.org/10.1016/j.ge...

Reviewing the biology & roles of #CancerStemCells (CSCs), their molecular pathways, and the mechanisms contributing to #TherapeuticResistance, with insights into the approaches for CSCs targeting emphasizing the potential of #DrugRepurposing. #OpenAccess: doi.org/10.1016/j.ge...

This recent review examines #FOXK2 expression across diverse #Tumor types, highlighting mechanisms of deregulation, & discusses its potential as a diagnostic & prognostic #Biomarker in #PrecisionOncology. @ufrjoficial.bsky.social #medsky #OpenAccess: www.sciencedirect.com/science/arti...

This latest study reveals that #CUDC907 & #temozolomide synergistically suppress GBM progression, with CUDC-907 reducing resistance by inhibiting #DNAdamage repair mechanisms, promising novel #therapeutic avenues for GBM. #medsky #OpenAccess: www.sciencedirect.com/science/arti...