📣 #ESMOBreast26: Get inspired and be part of the conversation shaping the future of breast cancer treatment and care. Last chance to register and save! ⏰ Deadline 26 February 2026 🔗 https://ow.ly/8RGA50YlJQm#ESMOBreast26 #esmomeetings

Join us for an IASLC webinar! This session will dive into practical radiotherapy strategies, staging insights, and multimodality care considerations for Stage III NSCLC. Register here: bit.ly/4tLVFm7 #LungCancer #NSCLC #Oncology #Radiotherapy #MedicalEducation

Researchers discovered that certain #ImmuneCells in early-life #skin are more reactive than in adults, which may explain why #eczema often begins in #childhood.  #AtopicDermatitis #DendriticCells #AllergicInflammation

Single-cell #multiomics profiling of #CML #bonemarrow shows reduced #CD4 naïve cells, expanded #CD8 terminal effectors, reduced TCR diversity, and altered immune signaling, highlighting CD8 TE cells as key drivers and therapeutic targets. #OpenAccess: doi.org/10.1016/j.ge...

Highlighting in vivo CAR T cell generation as a scalable, cost-effective alternative to traditional methods, while challenges related to #VectorImmunogenicity & off-target risks limit its clinical translation. #OpenAccess: doi.org/10.1016/j.ge...

IRF7-driven microglial #inflammation damages #neurons in #TemporalLobeEpilepsy by suppressing RORB–STIM1 signaling, highlighting IRF7 as a central regulator and promising #neuroprotective therapeutic target for drug-resistant TLE. #OpenAccess: doi.org/10.1016/j.ge...

#Glutamine homeostasis regulates PD-L1 via STAT3 in pancreatic cancer, while PD-L1 in turn modulates #mTOR activation to drive cell proliferation, highlighting a potent metabolic-immune target for #PancreaticCancer therapy. #OpenAccess: doi.org/10.1016/j.ge...

On #SCN2AAwarenessDay, we highlight SCN2A-related #epilepsy, #autism, and neurodevelopmental disorders—calling for discovery science, early genetic testing, and targeted therapeutics. Click here for #SCN2A research: www.sciencedirect.com/journal/gene... #GenesAndDiseases #NeuroScience #Genomics

This review describes aberrant #Sialylation as a critical driver of malignancy and #ImmuneSuppression, highlighting glycan-targeting strategies and sialyltransferase inhibitors as promising avenues for #PrecisionOncology. #OpenAccess: doi.org/10.1016/j.ge...

This review explores #m6A RNA modification and its crosstalk with others, detailing roles of writers, erasers & readers in regulating #geneexpression, disease, therapy response, and future RNA-based #biomarkers. #OpenAccess: doi.org/10.1016/j.ge...

This review describes the role of the transcription factor SOX4 in #LiverDisease & #HCC progression, highlighting it as a promising #TherapeuticTarget to modulate #Fibrogenesis and overcome #DrugResistance. #OpenAccess: doi.org/10.1016/j.ge...

🔬 Calling industry scientists! Share your story for the ASBMB Today Summer 2026 essay series. How do you approach discovery, problem-solving and collaboration? ✏️ 500 or 250 words | 📅 April 15 | 📧 [email protected] www.asbmb.org/asbmb-today/... #ScienceInIndustry #ASBMBToday

⏰ #Radiotherapy is more effective when administered at the right time of day, new research from 🇪🇸 @cabimer.bsky.social and @unisevilla.us.es finds. This discovery could open the door to #cancer “chronotherapy”.

Only days remain to share your abstract to #ESCCongress 2026. Influence what comes next in cardiology. Submit today & be part of the transformation. Deadlines: Abstracts: 1 March | Clinical Cases: 11 March https://ow.ly/M8wQ50YiKge#ESCCongress

In 12,715 pregnancies, #FirstTrimester lab markers with #MachineLearning improved #preeclampsia prediction, reaching AUCs up to 0.954 and outperforming #FetalMedicineFoundation, offering scalable precision #pregnancy care. #OpenAccess: doi.org/10.1016/j.ge...

This study maps spatio-temporal gene interactions during #amyloidβ accumulation using #SpatialTranscriptomics, uncovering ligand–receptor dynamics and transcriptional networks of #AlzheimersDisease etiology. @tulanemedicine.bsky.social #OpenAccess: doi.org/10.1016/j.ge...

#CancerAssociatedFibroblasts -derived fibronectin EDA drives #Sorafenib resistance in #HCC via SHMT1 activation, highlighting a novel fibroblast-tumor interaction that governs therapeutic response in #LiverCancer. #OpenAccess: doi.org/10.1016/j.ge...

Researchers map the interplay of #ProgrammedCellDeath after #IschemicStroke, showing early #ferroptosis and #necroptosis followed by #apoptosis, with iron driving both—highlighting the potential of concurrently targeting multiple death mechanisms. Read: doi.org/10.1016/j.ge...

📢 We are excited to anounce the upcoming ESMIT onsite course “𝗡𝘂𝗰𝗹𝗲𝗮𝗿 𝗠𝗲𝗱𝗶𝗰𝗶𝗻𝗲 𝗶𝗻 𝗙𝗨𝗢/𝗜𝗨𝗢: 𝗪𝗵𝘆 𝗔𝗿𝗲 𝗖𝗵𝗶𝗹𝗱𝗿𝗲𝗻 𝗗𝗶𝗳𝗳𝗲𝗿𝗲𝗻𝘁?” that will take place in April in Vienna. 🔗𝗦𝗶𝗴𝗻 𝘂𝗽 𝗵𝗲𝗿𝗲: https://esmit.eanm.org/event/nuclear-medicine-in-fuo-iuo-why-are-children-different/

A new study shows #RedBloodCells act as hidden #GlucoseSponges in #LowOxygen conditions, explaining why people living at #HighAltitude have lower #diabetes rates and pointing toward new treatments.  #Hypoxia #GlucoseSink #BloodGlucoseControl #GlucoseTolerance

Cancer vaccines are here, and research is identifying how to push T cells even further so they thrive in the tumor microenvironment. Learn more about the opening‑night #AACRIO26 keynote addresses from #AACRFellows Elizabeth Jaffee and Philip Greenberg on the #AACRBlog: buff.ly/uKglwKq

Overexpression of #Ferroptosis-associated antigens — CAV1, FTH1, and SLC3A2 —is linked with poor prognosis and immune cell infiltration in HNSCC, highlighting their potential in personalized #mRNAvaccine intervention. #OpenAccess: doi.org/10.1016/j.ge...

Upregulated STIM1 enhances SOCE in #sorafenib-resistant #HCC, activating CaN-NFAT to drive #SLC7A11 transcription, boost GSH, and suppress #ferroptosis; blocking this axis with SKF96365 restores sorafenib sensitivity. #OpenAccess: doi.org/10.1016/j.ge...

Researchers show that VPS13D regulates #EpilepticSeizures by modulating #MitochondrialFission and #Autophagy, suggesting therapeutic targeting of VPS13D-mediated mitochondrial dynamics as a novel strategy for #Epilepsy. #OpenAccess: doi.org/10.1016/j.ge...

This study identifies a BiP–FKBP9 axis that stabilizes FKBP9 to drive #glioma progression, linking high coexpression to poor prognosis and highlighting a promising therapeutic target to suppress #tumor growth and improve survival. #OpenAccess: doi.org/10.1016/j.ge...

Highlighting the bile acid–#GutMicrobiota crosstalk as a key modulator of the gut–brain axis, regulating #Neuroimmune function, barrier integrity, & #Neurotransmission, with therapeutic implications for neurological & #PsychiatricDisease. #OpenAccess: doi.org/10.1016/j.ge...

Great news! 🎉 The #ICNC2026, co-organised by #EANM & @asnc.bsky.social, has been accredited by the European Accreditation Council for Continuing Medical Education (EACCME®) for a maximum of 11 European CME credits (ECMEC®s). Don't miss out and register today! 🔗 icnc.community/registration/

⏰ Residents, medical specialists, and nurses in #NeuroOncology: Still 4 days to register! Join the #EANO Tumor Board 2026 – 5️⃣ multidisciplinary case-based discussions around the management of patients with glioma, combined with short lectures. 🗓 Registration deadline: Feb 23, 2026 👉 www.eano.eu

Have you submitted your abstract yet for #EACR2026 Congress (Budapest, 8-11 June)? Don't miss the exciting opportunity to showcase your research and build new connections and collaborations with the global cancer research community. You have until 04 March to get your submissions in: 2026.eacr.org

Scientists report that limited #TACE-induced #necrosis predicts post-transplant #HepatocellularCarcinoma recurrence, revealing a hypoxia-driven HIF-1α/LGR5/MAPK axis that boosts metastasis & positions #LGR5 as a key #biomarker and therapeutic target. #OpenAccess: doi.org/10.1016/j.ge...

Integrated #Multiomics reveals that GLP-1R agonist-driven proteins mediate #UlcerativeColitis (UC) risk via Notch signaling, offering a framework that identifies novel therapeutic targets & #Biomarkers for managing UC. #OpenAccess: doi.org/10.1016/j.ge...

#SingleCellTranscriptomics of #bonemarrow in #Type2Diabetes reveals impaired #cytokinesignaling, reduced #osteoclast activity, and diminished Cd36+ precursor differentiation, driven by dysregulated AP-1 transcription factor activity. #OpenAccess: doi.org/10.1016/j.ge...

#HighIntensityIntervalTraining alleviates #heartfailure by boosting skeletal muscle–derived #Metrnl, which activates AMPK-HDAC4 signaling in #cardiomyocytes to enhance GLUT4 expression, aerobic glucose metabolism and mitochondrial function. #OpenAccess: doi.org/10.1016/j.ge...

#HepatitisBvirus core protein stability is sustained by host factor PSME1, which prevents HBc degradation via the #26Sproteasome; silencing PSME1 reduces HBc levels & HBV transcription, identifying PSME1 as a novel #biomarker for chronic #HBV. #OpenAccess: doi.org/10.1016/j.ge...

STING drives pressure overload–induced #CardiacFibrosis and remodeling by promoting #inflammation, oxidative stress, and fibroblast activation, while #mitophagy limits cytosolic #mtDNA and STING signaling. #HeartFailure #OpenAccess: doi.org/10.1016/j.ge...

Researchers have developed a high-efficiency #AdenoviralVector system by using GAPDH to suppress #Adenovirus-induced #OxidativeStress, enabling rapid recombinant adenovirus production for #GeneTherapy. #OpenAccess: doi.org/10.1016/j.ge...

TRUSTroke will present a "Special Session on Federated and Trustworthy AI solutions for Predicting Clinical Outcomes: From Theory to Real-World Clinical Impact" at BIOSTEC/HEALTHINF 2026 on 3 March in Marbella, Spain. 👉 Find the full session agenda here: https://loom.ly/p7-xxAw

Register by February 17 to get the lowest rates for the AACR Special Conference on Brain Cancer (March 23-25, 2026; Philadelphia), chaired by Stephen J. Bagley, Michelle Monje, and Mario L. Suva. Learn more: buff.ly/9MkKUbq #AACRbrain26 @michellemonje.bsky.social

#ICHNO26 🔔 Late registration is still open! Register by 25 Feb 🔗 https://ow.ly/ALal50YbKWf#ICHNO26Strengthen clinical decision-making with cutting-edge science, randomised trial updates & multidisciplinary expert exchange 📍 Seville | 19–21 March 2026 #HeadAndNeckOncology #esmomeetings

This review explores how #HistoneDeacetylases regulate #VascularHomeostasis via endothelial and smooth muscle cells, highlighting their role in vascular #Pathogenesis and the therapeutic potential of #HDACinhibitors. #OpenAccess: doi.org/10.1016/j.ge...

An overview of MDM2’s role in regulating #CancerImmunotherapy, summarizing preclinical & clinical findings on #MDM2 inhibitors in combination with #Immunotherapy, and highlighting MDM2 inhibition as a therapeutic strategy. #OpenAccess: doi.org/10.1016/j.ge...

Using a #Multiomics approach, this review defines novel #PDAC molecular subtypes to overcome #TumorHeterogeneity, providing a robust framework for identification of novel #TherapeuticTargets and #PersonalizedTreatment. #OpenAccess: doi.org/10.1016/j.ge...

A comprehensive overview of the origins of #EndothelialCells in hypoxic & #TumorAngiogenesis, the key regulatory molecules, with discussion of the advances, challenges, and future directions of #AntiAngiogenicTherapy. #OpenAccess: doi.org/10.1016/j.ge...

This review highlights how #diet acts as a powerful evolutionary force shaping #GutMicrobiome composition and function, driving microbial adaptation that influences metabolic health, #diseaserisk, and personalized nutrition strategies. #OpenAccess: doi.org/10.1016/j.ge...

Did you know @iasp.bsky.social’s #GlobalYear2026 is about neuropathic pain? Listen to the newest episode of Pain Exchange, featuring President Andrew Rice, @lampertlab.bsky.social, and @neiloconnell.bsky.social speaking about the goals of the campaign and more bit.ly/49S5XsZ

🎧 New #LungCancerConsidered episode Dr. Molly Li leads a conversation with Dr. Shuben Li and Dr. Calvin S.H. Ng on surgical management of early-stage #NSCLC, including VATS, resection approaches, endobronchial therapy, and tubeless anesthesia. Listen now: bit.ly/464OFGN #GlobalOncology #LungCancer

What’s in store for #TTLC26? 🧬 The Conference Chairs share key programming highlights, breakthrough data to watch, and why this year’s meeting is one you won’t want to miss. Get the preview in ILCN: bit.ly/3MoKSO4 #LCSM

#SingleCellAnalysis reveals #ATF6 drives #EpithelialMesenchymalTransition in #LensEpithelialCells, promoting #fibrosis & #cataract progression; inhibiting ATF6 reduces #STAT3 activation, highlighting ATF6–TAK1 signaling as a therapeutic target. #OpenAccess: doi.org/10.1016/j.ge...

An overview of how age & #Obesity in postmenopausal women drive #BreastCancer through the release of pro-inflammatory cytokines and CXC chemokines, highlighting their potential as targets for #Theranostic interventions. #OpenAccess: doi.org/10.1016/j.ge...

This review examines #MetabolicReprogramming in #HeadAndNeckCancer, detailing glucose, amino acid, and #LipidPathway changes plus immune alterations, and highlights metabolic targeting as a promising strategy for therapy development. #OpenAccess: doi.org/10.1016/j.ge...