A Sharon Begley byline, almost 5 years after her death. Upon hearing the news James Watson had died, a STAT reporter said in our Slack, "I wish I could read what Sharon would have written." Incredible news: Sharon in fact did pre-write a Watson obit. And it is masterful and excoriating. 🧪🧬🧫

This really hasn’t gotten enough attention this week. @wired.com #ICE www.wired.com/story/fbi-wa...

You don't have to move here but I would not recommend staying there. #ScienceSky journals, seriously, get rid of the "X" button, that place isn't safe to direct ANYONE. #MedSky journals and #AcademiaSky do the same. Ain't worth keeping a toe in poison waters. 🧪🩺

A man was arrested for playing Darth Vader's theme music, "The Imperial March," behind National Guard troops walking through Logan Circle. Now the ACLU is suing on his behalf. storage.courtlistener.com/recap/gov.us...

One of these is the White House @whitehouse-47.bsky.social . The other is Dnipro, Ukraine. What are the common factors?

The White House is asking people not to share pictures of the East Wing because it’s even worse today.

Breaking News: Paul Ingrassia, President Trump’s nominee to lead the Office of Special Counsel, said he planned to formally withdraw his nomination due to lack of Republican support. His path began to unravel after a report that he sent a series of racist text messages.

NO KiNGS protest in New Haven made it onto Rachel Maddow. Check it out at 3:25— youtu.be/WjSCy54LqaI?... And yes, @JEFFREYTOWNSEND.BSKY.SOCIAL (bsky.app/profile/jeff...) is me.

Page One. @latimes.com

Page One. @bostonglobe.com

No Kings Willimantic. 3500 or so.

Hell yes, Pittsburgh. Love Yinz. No Kings.

Best sign so far. #NoKingsDay

No Kings-Los Angeles, CA

Giant copy of the Constitution being carried down Pennsylvania Avenue.

NO KiNGS IN NEW HAVEN

NO KiNGS IN NEW HAVEN

I'm attending No Kings's event, “DENVER NO KINGS II: Return of the Resistance!” - sign up now to join me! www.mobilize.us/nokings/even...

“Constant cutting of good science is eventually just gonna erode all of the progress that we made in terms of disease treatments and interventions and public health,” Dr. Irene Yang, a registered nurse and health researcher, said. (Published August) www.thexylom.com/post/atlanta...

"Columbia’s leadership must act with courage rather than capitulation. The future of the University is not a matter of federal negotiation. Making “deals” with this federal administration will not save us. " This.

gave a talk on "Why Cancer Isn’t the Same at Every Age: Lessons for Prevention and Care" at the Joint Retreat on Aging and Cancer Research, sponsored by @yalecancer.bsky.social Program in Genomics, Genetics, and Epigenetics among others including many engaged representatives of the local community.

gift link. unreal to see this happening, but it's unfortunately necessary. wapo.st/46QspkQ

Republican funding proposal could cost thousands of lives. www.ctpublic.org/news/2025-10...

Just out in Lung Cancer: KRAS G12C-associated immunotherapy benefit in NSCLC is substantially mediated by tobacco-induced tumor mutation burden—not allele-specific effects. authors.elsevier.com/a/1ls3ocYZOi...

Flu & covid vax day — & I’m still uncertain which mRNA to ask for. Do I wait for Novavax availability? Last year the other place was all atweet with knowledgable opinions; this year I‘m lost. “One of those” plus the added idiocy of my 4th guess. Wordle 1,574 5/6* ⬜🟨⬜⬜⬜ 🟩⬜⬜🟩🟩 🟩⬜⬜🟩🟩 🟩🟩⬜🟩🟩 🟩🟩🟩🟩🟩

Some #lungcancers with #KRAS G12C mutations respond to #immunotherapy bc of⬆️ mutation load from #tobacco exposure. Smoking history + overall mutation burden are better guides for treatment than KRAS status alone. lungcancerjournal.info/article/S016... @jeffreytownsend.bsky.social

DISNEY: "OK, we are putting Jimmy Kimmel back on the air. You can resubscribe now." ME: "I unsubscribed because you immorally bowed to fascism. I'm not going to resubscribe because you immorally bowed to finances."

Neither Elon Musk Nor Anybody Else Will Ever Colonize Mars - defector.com/neither-elon...

Bye bye, rodent nation. #BoycottDisney

will be speaking in The Distinguished Speaker Series: AI & Health Science 📅 September 19, on “Dismantling the Coarse Paradigm of Cancer ‘Drivers’ and ‘Passengers’” 📍 University at Buffalo Clinical and Translational Science Institute In person or Zoom — register 🔗: qrco.de/AIHS-DSS

Student performance tracks district income—linear in some states, leveling in others. It’s steepest in less-affluent states, and math slips from grade 3→8. Our kids deserve better than fate by zip code—and the variance in slope tells us we can do better. 🔗 journals.plos.org/plosone/arti...

Photo passed along from a federal employee from inside the Dept of Labor building, where a giant Orwellian image of Trump's face is now draped outside. Big Brother is watching.

Sam Hart describes and applies a method to distinguish differences in mutational processes between groups of cancers without signature decomposition (joint work with @kelleyharris.bsky.social and in collaboration with @nalcala.bsky.social )! #Genomics 🖥️ 🧬 www.biorxiv.org/content/10.1...

Elena Romero led a new preprint detailing joint work with Lillian Cohn's lab at Fred Hutch describing really crazy parallelism in in vivo HIV escape from broadly neutralizing antibodies! #VirEvol #evoSky www.biorxiv.org/content/10.1...

California, Oregon and Washington announced yesterday they’ve created their own health alliance, saying the CDC has become “a political tool that increasingly peddles ideology instead of science.” New York, Massachusetts, Connecticut, Delaware, Pennsylvania and Rhode Island have now done the same.

Gov. Kathy Hochul signed an executive order Friday morning explicitly allowing pharmacists to prescribe and administer the shot to New Yorkers who request it.

This is THE WAY, but build a Coastal Coalition including all Pacific, Atlantic, (& Great Lakes?) States. Everything that is defunded at the federal level we can build up Coastally. Because Coastal States are net givers federally, defunding federally then equals a net benefit for coastal states.

Assistant/ Associate Professor of Mycology at UGA - Go be part of a Legendary Fungal Group fungi.franklinresearch.uga.edu and dept of plant pathology plantpath.caes.uga.edu www.ugajobsearch.com/postings/445...

Stellar work by graduate students to build this comprehensive dataset of antifungal resistance mechanisms. Kudos and congratulations to the Landry lab @christianlandry.bsky.social www.nature.com/articles/s41...

New paper led by @yadirapga.bsky.social! Opossums have babies at 6-months of age, but are still highly male-biased in their mutations academic.oup.com/genetics/adv...

Well, well, well…this bodes well for Whackadoodle limiting access to the Covid vaccine now doesn’t it? www.kctv5.com/2025/08/28/k...

New Proc B study 🧪 reveals up to 8.5× differences in muscle mitochondrial efficiency across ectothermic vertebrates. Evolution tunes energy, leak, and ROS control in surprising ways. 🦎🐸🦎 #Evolution #Mitochondria royalsocietypublishing.org/doi/abs/10.1...

The September cover of Molecular Biology and Evolution features the work of Zhang et al., who studied the genetics of cave adaptation in Triplophysa fish. 🔗 doi.org/10.1093/molbev/msaf175 📷 Yahui Zhao / Fanwei Meng #evobio #molbio

I hope to take a PhD student in the coming application cycle. Please reach out if you are interested in joining our lab in EEB at Yale, especially if interested in working on the natural history/ phylogenetics/ morphology/ population biology/ development/ genomics of siphonophores. dunnlab.org

💡 Cancer cells don’t just mutate—they reorganize their DNA in 3D space. Our new study shows how the genome’s folding pattern shifts as tumors progress, cell by cell 🧩🧬. It’s the first 3D genome atlas of cancer progression. Thread 👇

7/ This was a close collaboration with @sstevenwang.bsky.social. Kudos to #MiaoLiu, #SherryAgabiti, and #ShengyanJin for leading the effort with critical collaboration from @christianfruiz.bsky.social @jeffreytownsend.bsky.social @yalecancer.bsky.social and funding from #NCI @theaacr.bsky.social