Thermo Fisher has responded to research integrity activists who spotted apparent manipulation in its antibody catalog: "In ... preparing antibody images for publication on our website, some images may have been adjusted to clarify for presentation purposes." More: cen.acs.org/research-int...

LOL last night Stephen Colbert spent an hour hosting public access "Only in Monroe"

Earlier this week I posted an example of a fake western blot provided by ThermoFisher to demonstrate the validity of a p53 antibody. I considered it an amusing curiosity. In fact Thermo Fisher Scientific has systematically manipulated antibody validation data!

Life hack from a marine biologist: When your blue sea dragons need a little snack, remember that they never evolved to swim, so you have to drive the Portuguese man-o-war around and pick them up like a little bus 🎥 by me during field work :)

Revival Of Internship Program Heralds CEO’s Daughter Coming Of Age https://bit.ly/3PuB1I2

May 18, 1980 | 8:32 a.m. The ground shudders. A M5.1 quake hits beneath Mount St. Helens. Weakened critically, the north face bulge collapses outward. Within seconds, a pyroclastic density surge bursts through the disintegrating slope. The clock strikes zero.

We are implementing a similar policy at @arxiv.bsky.social. If there is incontrovertible evidence of LLM slop in a paper, this means the authors did not take the time to read the LLM output and we can't trust anything else in the paper. Penalty is 1 year ban from arXiv followed by...

Breaking news: Indiana University plant microbiologist Roger Innes has been locked out of his laboratory by the school in response to a request by one of his federal funders. The move comes after Innes complained about the government’s prosecution of Chinese postdocs. https://scim.ag/4tsDqRr

How do fungi grow directionally? We think part of the mechanism involves local translation of mRNA near the tip, especially of cell wall components. Delighted to share our preprint showing that an RNA-binding protein, SsdA/Ssd1, is trafficked to the tip of growing fungal filaments.

FDA grants breakthrough device designation for schizophrenia/bipolar bloodtests, based on below paper with n=30 per disorder, "using 'leave-one-out' analyses, indicating that the models should be predictive when applied to independent data cohorts." Ouch. pmc.ncbi.nlm.nih.gov/articles/PMC...

It is with great sadness that we announce J. Craig Venter has died. 🧪🧬 www.jcvi.org/media-center...

This is an actual line that was added to the official system prompt for Codex for GPT-5.5 by OpenAI. Usually the system prompt is as minimal as possible, so I assume it would otherwise mention goblins a lot. AIs are weird.

UPDATE: No audience questions were taken for Jay's talk.

📣 Exciting news: my lab is moving to the Krembil Institute at the University of Toronto’s University Health Network in Fall 2026. We’ll be recruiting for all roles, so reach out if you’re interesting in joining us to study spinal circuits for sensorimotor control www.levine-lab.org

I read Vigilance by Robert Bennett a couple years ago and thought 'this is kinda over the top and a little unrealistic' I owe that book an apology

it’s First Communion Sunday at Mass which means it’s time for my favorite thing in the world: TINY FORMALWEAR

THREAD All the Colours of the Rainbow At Altmetric we look for where research has been shared and cited online. In addition to granting us permanent entry into Pride Month, the Altmetric rainbow matches different sources of attention to research that we find. What are they all? Let's go: 1/24

Would like to dedicate this post to the people who yelled at me for giving the Sabres 58% to make the playoffs in my season preview this past summer.

yes. they pay more based on income in taxes for the thing that is then “free” for everyone. this is how public services work

@nygenome.org is hiring Genomic AI Fellows! (fancy postdoc positions) If you're interested in working at the interface of AI and genomics in a great environment please apply at: jobs.silkroad.com/NYGenome/Car...

If all goes according to plan, in a few hours, a crew of astronauts will begin a journey that will take them on a loop around the moon. Here's a video that NASA put together to help people visualize the journey through space, first orbiting the earth before looping around the moon and flying home 🔭

this is so stupid. you simply cannot do behavioural research this way. the core question here is how humans act in this situation and at the risk of having to explain a methodological point so basic it should never have to be said, you need humans for that

sorry i never responded to your email, i didn't want to and then i forgot

I just heard back from the reporter, and I am genuinely speechless. Is “we don’t care” the business model?

My motivation for perservering as a statistician even when it feels bleak comes from Ian Gordon: sometimes the best we can do is make sure that the research that gets done is better than it would have been if we weren't involved in it

Check out the newest work from our, from Fabricio Nicola @fabricionicola.bsky.social on mouse jumping and spinal cell types. Excellent collab with @vulcnethologist.bsky.social www.biorxiv.org/content/10.6...

Pretty much the same reason all the gene regulatory network inference models don't work as well as people think they do

New paper showing that much of the apparent success of protein language models in predicting mutational effects is a mirage: These models mostly memorize sites. 1/ www.biorxiv.org/content/10.6...

Excited to share this preprint that describes my latest work on using GPUs to accelerate processing of RNA-seq data. The title says it all: "RNA-seq analysis in seconds using GPUs" now on biorxiv www.biorxiv.org/content/10.6... and github github.com/pachterlab/k... Figure 1 shows they key result

sem condições esse daqui

I get asked to show up to book clubs, online and offline. Here is why from now on the answer is always "no." If you think this might have something to do with "AI" ruining yet another thing for everyone, you're absolutely 100% correct. whatever.scalzi.com/2026/03/03/i...

Critics say that Trump's war with Iran could have a lot of blowback. But there is no historical precedent for the United States overthrowing an Iranian government and then facing 50 years of hostility from Iranians.

Crap www.online-tribute.com/DavidBotstein David Botstein passed away. I worked with him at Stanford for a few years in designing and teaching a course on "The Heart". My heart is heavy right now. He was a wonderful mentor.

crying in the club* (*at my desk) bc stanley tucci took the USA women's hockey team out for a meal at his favorite restaurant and they gave him his own jersey

they need to import this to the Stanley Cup playoffs, watching hockey players be handed stuffed animals while they seethe is the new funniest thing in the world

the only place this should happen is academic conferences

Our paper is now out in Nature: “Ancient co-option of LTR retrotransposons as yeast centromeres” www.nature.com/articles/s41... A short thread on how retrotransposons helped give rise to yeast point centromeres. 1/14

🧵 After years out of the field, I and my lab are again working on bacterial type IV pili. We have just posted our first preprints, and I'm excited to share what we have discovered. This shows Neisseria gonorrheae bacteria infecting a human epithelical cell. Here, you can see the pili in red. 1/

🧪🧬New preprint We present cryo-EM structures of reconstituted CTCF–nucleosome complexes, showing CTCF dimerization drives nucleosome oligomerization into defined higher-order assemblies. Disrupting CTCF–CTCF interfaces in mESCs reduces looping and impairs differentiation. tinyurl.com/CTCF-nucleos...

woke up and chose linguistics violence today: the word 'queue' is just the letter Q followed by four silent letters waiting in line behind it. they're literally queuing. this is the most honest word in the english language and i will not be taking questions at this time

I'm thrilled to anounce that our latest study on ALS/FTD neurodegenerative diseases has been published. Very proud to be part of this excting project. Many thanks to Clotilde Lagier Tourenne for an amazing longlasting and fruitfull collaboration, #ALS #FTD #Ribosomes www.science.org/doi/10.1126/...

Very cool paper measuring pedestrian volumes on NYC streets and examining crash risks: "Intersections with the highest pedestrian injury risk are often outside Manhattan, where exposure-adjusted danger is the greatest." www.nature.com/articles/s44...

The eastern shore of Lake Michigan - between South and Grand Haven - is loaded with mountain ranges of ice 😱

BLAZING SADDLES was released 52 years ago today. Acclaimed as one of the great comedies of the 1970s, and among the most popular of director Mel Brooks, the story of how it was made is a cascading waterfall of creative alternatives... 1/36

A sad day at NIH... The NIH Record was a great way for NIH folks to find out what was going on across NIH. Many important stories published there over the years. nihrecord.nih.gov/2026/01/30/n...

seriously: I really enjoy using matplotlib now. youtu.be/5ZxczGlrkyQ

My (now) weekly update on 2026 NIH funding. New and competitive renewal awards. 3 new awards (compared to ~100 expected based on recent years). No new ICs... still just NIA, NINDS, NIDCD, and NIDCR. 1/2

Holy hell, what an obituary

once again being driven insane by ML conference submissions

Excited to share this with #BlueAndGoldSky Hasek took us back to the rink he grew up on in Pardubice, Czechoslovakia and introduced us to the people who had the greatest influence on his young life.