New Online! The mechanistic basis and cellular functions of UFMylation

URichmond is hiring two tenure-track faculty. One in biochemistry/chemical biology and the other in experimental physical chemistry. This is a terrific place to work - our focus is on our talented undergraduates and we have robust research resources. chemistryjobs.acs.org/job/assistan...

Excited to share our new paper led by recent PhD, Dr. Hannah Schmidt! We found that UFMylation unexpectedly promotes flavivirus particle production by specifically regulating viral assembly. Check it out! #virology #UFMylation #flaviviruses journals.asm.org/doi/10.1128/...

The Wadsworth Center is expanding it's research focus on #virology /vector-borne diseases! www.asmcareerconnections.org/job/research-scientist-5-g-31/78488664/ This is a unicorn assistant prof equivalent position with 12-month hard money salary and no teaching commitments (!) Reposts appreciated 🙏

A study reveals the effects of Florida's new public university post-tenure review: * higher rate of faculty departure * younger star faculty were more likely to leave * new hires were less likely to be stars * low-performing faculty didn't increase their performance papers.ssrn.com/sol3/papers....

We are looking for a talented Research Assistant to work in the #RNATherapeutics Core Facility at the @ircm.bsky.social in beautiful Montreal. More details on the position and on how to apply here: www.ircm.qc.ca/en/position-...

www.sciencedirect.com/science/arti... @drbadbug.bsky.social @teresaomeara.bsky.social Overall, our findings illustrate non-canonical IRE1α activation during infection and a function for IRE1α in supporting organelle contact sites to safeguard against rapidly growing microbes.

Congrats Mike et al!!

Super psyched to have leading investigator @thehornerlab.bsky.social presenting her team's work THURSDAY 15th May on Zoom. #flavivirus #virus-host-interactions #innate_immunity #DENV #ZIKV All are very welcome and please re-post to get the word out. Email organisers for Zoom link. See you there!

Terry Dermody and I wrote an op-ed about chronic diseases ("Make America Healthy Again"), the role of viral infections, and how virologists can help. www.post-gazette.com/opinion/gues...

The National Institutes of Health, the largest funder of biomedical research in the world, has fired 1,300 employees and cancelled more than $2 billion in federal research grants. https://cbsn.ws/4daiCrv

New report shows that NIH grants fueled $95 billion in economic activity and 407,782 jobs in 2024. That's not to mention the countless lives that biomedical research has saved. Show me a better investment than that. www.forbes.com/sites/michae...

Inspiring speakers highlighting the importance to our collective health as well as economic return on investment of basic, curiosity-driven research at yesterday’s @standupforscience.bsky.social Frightening to see active dismantling of decades of public investments in our health and futures.

Great story by AP’s Mayika Seminara about how Duke scientists are responding to uncertainty. apnews.com/article/trum...

Not only are we limiting our medical research and advancement of new treatments, but NIH cuts are affecting ability of universities to take on grad students, limiting our future workforce @altcdc.altgov.info @altnih4science.bsky.social #science #cuts #resist apnews.com/article/trum...

Trump Administration Stalls Scientific Research Despite Court Ruling www.nytimes.com/2025/02/21/s...

Finally a Friday evening with GOOD news 🙌🏽 So grateful for people who are willing to stand up and fight for what’s right instead of prematurely bowing to injustice.

🚨BREAKING: Federal Court GRANTS sweeping nationwide injunction against Trump DEI executive orders finding that they violate First and Fifth Amendments to the Constitution. A huge victory for @democracyforward.org and its clients. A stinging loss for Trump. Visit www.democracydocket.com for details.

A large portion of grants awarded by the U.S. National Institutes of Health cannot be funded for the foreseeable future because of an indefinite hold on submissions to the Federal Register, according to an email reviewed by The Transmitter. By @avaskham.bsky.social bit.ly/3X8ngz8

I had two grant proposals up for review in the NIH Bacterial Virulence (BV) study section. It was canceled without notice this morning. Without those grants, my lab must close within a year. And so the purge of scientific research in the US continues 🤬 #MicroSky 🦠🧫🧪🧬🔬

I just covered this for @thetransmitter.bsky.social — will keep following! www.thetransmitter.org/funding/fede...

So a former postdoc from our department had just started as a PO at NIH and was terminated in the wave of terminations last week. He is in the research triangle and a phenomenal scientist with expertise in stress and glia. If anyone in the RTI is hiring asap please let me know! #neuroskyence

This is gut-wrenching 😭😱https://www.bmj.com/content/388/bmj.r294

ATTENTION (PLEASE SHARE) If anyone has or knows of any positions that might be appropriate for the NIH staff members who were terminated, please post the information in this thread. There are lots of talented and accomplished people who may be looking for new opportunities.

Executive wants to frame the NIH indirects cut as $4B in savings. But given that NIH returns $2.5 on every $1 investment, this would actually cost US economy a net $6 BILLION (per year!). Not to mention the human costs of wrecking education and research sectors and the communities they serve.

🚨RED ALERT for 🧪: The Trump NIH just gashed indirect costs. This is a direct attack on universities. “Pursuant to this Supplemental Guidance, there will be a standard rate of 15% across all NIH grants for indirect costs.” 😮 Just a devastating Friday night news dump. #scicomm #academicaky

A fantastic paper from @immunuelle.bsky.social & @mgalejr.bsky.social. New insights into RNA sensing of viruses. www.sciencedirect.com/science/arti...

#HigherEd, head’s up: two of the plaintiffs here are AAUP and the national association of DEI offices. they’re suing trump + the whole cabinet. one to watch.

Excellent perspective by @lisamjarvis.bsky.social @bloomberg.com on the deep freeze at NIH

Our paper on how Zika virus hijacks microcephaly protein ANKLE2 to promote virus replication is now out at mbio! Special congratulations to first author Adam Fishburn and thanks to our collaborators Claudia Ruckert and Matt Evans. journals.asm.org/doi/10.1128/...

Really cool work from @thehornerlab.bsky.social and colleagues highlighting a role for the UFMylation post-translational modification system in flavivirus viral particle production!

#InterferonPower! Fantastic @science.org by @nandangokhale.bsky.social @ramlabuw.bsky.social &co! MAVS is intrinsically capable to sense via an unstructured region the 3’ UTRs of self mRNA (ISGs too!) to potentiate the response to viral RNA via phosphorylation of IRF3 & NFkB!

I am so excited to join the faculty in the Division of Immunobiology at Cincinnati Children's Hospital Medical Center in March 2025. My lab will study how RNA biology regulates and is regulated by infection and immunity. We'll be hiring at all levels in 2025 - stay tuned! www.gokhalelab.com

Our work on cellular RNA interactions with MAVS that promote antiviral signaling is finally live. So grateful to our indispensable collaborators as well as reviewers who helped to strengthen our work. #RNA #innateimmunity #virology @ramlabuw.bsky.social www.science.org/doi/10.1126/...

HPV vaccine doesn’t “just” prevent cancer. It also prevents precancerous lesions and other conditions like recurrent respiratory papillomatosis. In addition, the HPV vaccine also saves the United States $9 billion per YEAR in direct medical costs. www.sciencedirect.com/science/arti....