Proud to share the yeast telomerase structure, led by the talented @hongmiaohu.bsky.social in collaboration with the Wellinger and Chartrand labs. Discovered 37 years ago and took us nearly 7 years but totally worth the wait 😍. www.science.org/doi/10.1126/... www.youtube.com/watch?v=gFE4...

Action Item...Action Item...Action Item Time to comment on the Framework for the NIH-Wide Strategic Plan grants.nih.gov/grants/guide... Comments due by May 16, 2026

Yay Kelly-they made the perfect choice!

"I hear from current NIH staff regularly. They describe a particular kind of exhaustion: not just from overwork, but from the cognitive load of performing normalcy while privately managing fear." elizabethginexi.substack.com/p/what-nih-s...

Happening now on 50th Street in Minneapolis. Lined up over a ten block stretch.

So, so, honored by this award—it is daunting to know that my heroes have won this award! Thanks to my heroes and mentors, and my trainees, who are everything!!!!

I would ask people to call or message their senators about this and specifically that Vinay Prasad needs to be out at FDA. Even the Wall Street Journal has said as much. There is push back. Companies won’t fund clinical trials if they can’t trust the FDA.

Horse and eagle my favorite commercial so far

Yay Joe!! I am so proud!! This is so deserved—the Bass lab depends on you for everything.

The RNA Society is welcoming submissions of original infographics about any and all things RNA! Scan the QR for details!

Any academic folks on H1B visas (even with stamps in passports) please get legal advice from your University attorneys before leaving the US.

New #miRNA paper from Lai lab!! 🧬🔥 some think this field, despite recent Nobel to Ambros and Ruvkun, doesn't have much surprises left. but, do we EVEN KNOW WHAT a miRNA precursor LOOKS LIKE? we found some conserved miRNA hairpins up to 10x longer than suspected. this is mir-12, just bonkers! 1/n

🚨IT'S HAPPENING!🚨 Register now and join us in beautiful southern Chile in September for a new edition of the Molecular Biosystems Conference! @molbiosystems.bsky.social

We are hiring at all levels, so please help spread the word! #RNAsky #ribosomes #signaling #translation sinha.biochem.utah.edu/join

🎉 We're so excited to announce the 2025 #MySciJourney Challenge: A #scicomm competition for researchers to share their authentic journeys in science with students, teachers, & the broader public! 🧪 💸 $1k in cash prizes, thanks to @ncse.bsky.social! 👉 www.galacticpolymath.com/blog/my-scij...

Joining an increasing number of people publicly demanding RFK’s removal as HHS Sec: Dr. Bill Foege, a literal (6’6”) & figurative giant of public health. He served as a CDC director under Carter & Reagan, & is credited with designing the ring vaccination strategy that enabled smallpox eradication.

"What I would simply say is cancer can't wait." --Richard Schlueter, a 56-year-old metastatic cancer patient whose therapy was delayed due to terminations at NIH.

Join the 22,339 people who have joined to support our NIH colleagues. Let's get this to 50,000 RT

I have been updating my dashboard (jeremymberg.github.io/jeremyberg.g...) to add important material about the #BethesdaDeclaration 1/n

"We are speaking on behalf of hundreds of NIH staff who are standing up together to say: WE DISSENT. I am so scared about doing this but I am trying to be brave for my kids because it's only gonna get harder to speak up." Thank you to Dr. Jenna Norton and NIH scientists for your courage!

This might be helpful: www.regulations.gov/assets/files...

The notice and COMMENT PERIOD OPENED TODAY AND CLOSES MAY 23. Anyone who would like to register an objection or comment should go to this page and click on the green “public comment” button at the top: www.federalregister.gov/documents/20... 6/n

Anyone have advice on how to justify a budget increase on a renewal of a senior MIRA? I know, dreaming, but want to dream right. thanks, thanks for any advice.

Now online! Integrator loss leads to dsRNA formation that triggers the integrated stress response

Canadians 🇨🇦 abroad - you can register to vote in the election! You need to do it soon. www.elections.ca/content2.asp...

For your enjoyment: here is Secretary of Education Linda McMahon talking about implementing AI in schools, but pronouncing it "A1," as in "A1 Steak Sauce" www.youtube.com/live/lxrg28z...

we need to remember that these small wins are because people SPOKE UP -- keep calling your representatives, keep writing op-eds in your local papers, your voice matters! #resist

“a 400-year-old institution should be making decisions with a time horizon of centuries, not news cycles. Making a principled stand now…is the single best thing Harvard could do to earn its continued place as a symbol of genuine excellence” www.bostonglobe.com/2025/04/04/o...

Really bad news here:

Make this go viral! Her husband’s life was put at risk by the Signal texts.

www.eventbrite.com/e/stand-up-f... please reskeet and spread the word! 🧪

Working on a story for @sfchronicle.com about the administration's impacts to science, including #NIH and #NSF funding. Hoping to chat with early-career scientists, especially grad students and postdocs, about how you've been affected. Thanks! Signal: jacklee.55

I think it's going to happen: techcrunch.com/2025/03/01/m...

Great speech from Rep Jake Auchincloss (MA) - worth 3 mins of your time.

I believe we have breaking news in Inside Medicine. I spoke to a member of the FDA vaccine committee who confirmed that the meeting to decide the 2025-2026 flu shot composition was abruptly canceled today. My on-the-record Q&A with the FDA advisor: insidemedicine.substack.com/p/scoop-fda-...

This is a powerful (and accurate) speech both about curiosity driven research and about which institutions would be most hurt by a 15% cap on indirect cost rates (smaller academic med centers) and who would benefit (China). 1/2

Brilliant protest. Yosemite National Park workers hung an upside-down American flag — traditionally a symbol of distress or a national threat — thousands of feet off the ground on the side of El Capitan.

We are looking for a new Executive Editor on the journal, with @katherine-brown.bsky.social taking on a new role at @biologists.bsky.social. If you're an experienced editor with a love of developmental biology and its community, this could be the job for you. Full details in the link below.

F99/R00 AND K99/R00 DIVERSITY AWARD APPLICANTS If you have applied for a F99/R00 or K99/R00 Diversity award and the study section for review is not listed on your eRA Commons page, please reach out to me. DM me, email [email protected], Signal jeremymberg.78 THANK YOU

Normalize pronouncing DOGE as DOUCHE.

Here's what that hallway looked like before at NIH. (h/t @ivancalcantara.bsky.social)

A Primer on Indirect Cost Rates

The Howard Hughes Medical Institute, the nation’s largest private funder of biomedical research, yesterday killed a $60 million program aimed at making universities’ STEM education more inclusive. scim.ag/3EtS0US

Spread the word #AcademicSky if you or someone you know is being impacted by the fed funding freeze, @motherjones.com wants to hear from you!

Some of the EPA science advisory boards are being fired and the websites scrubbed of names tonight. Just putting this here as it seems likely the Board of Scientific Counselors is next - it's been a wonderful honor to serve the past few years.

Excellent article by colleague and mirror biology expert Michael Kay about the promises of mirror peptides and the perils of synthesizing mirror bacteria. undark.org/2025/01/16/o...

1/n So, this is out in NAR, finally. The longest, the most expensive and the most challenging project in the lab. Sparked by controversy concerning mammalian antiviral RNAi and our identification of Dicer variant, which is sufficient to increase RNAi. doi.org/10.1093/nar/...

One of my favorite traditions - we give each other really terrible hints that won't actually help you guess their gift K1's hint for her little sister: one of your gifts is covered in microbes Her hint for me: one of your gifts is made up of molecules

My colleague Dr. Helena Safavi has a postdoc opening--a chance to apply your machine learning/bioinformatic skills to the study of bioactive peptides (of cone snail fame). Check it out on linked in: www.linkedin.com/posts/helena...