Very saddened to learn that @wellcometrust.bsky.social has decided to no longer fund Irish researchers through their discovery grants. This is a major blow for those who do truly blue skies research in Ireland as the ecosystem (i.e. @researchireland.ie) only funds research with perceived "impact"!

Research Ireland’s 2026-2030 plan to distribute €4.55 billion public funds is structurally, rhetorically & materially focused on commercially translatable research rather than supporting bedrock, fundamental, discovery & public good research. Sign to demand reversal openletter.earth/concern-abou...

Great to host the @aicc-ireland.bsky.social symposium in @ucddublin.bsky.social yesterday! Super day and looking forward to next years event already! Thanks to all who made the trip and congrats to our prize winners!

Academia feels increasingly like playing Monkey Island, if you miss something as absurd as picking up a rubber chicken with a pulley in the first scene, you only realize much later that you’re stuck and can’t pass to the next stage (👇 see below 1/3) www.science.org/content/arti...

What should Europe do when demand for #ERC funding keeps rising? Restrict access or invest in excellence? Please read our open letter calling for reconsideration of the ERC 2027 resubmission restrictions & for constructive alternatives that preserve openness Consider to share & sign - see below 🧪

📅 Webinar reminder! Join us this Friday for @kjarmache.bsky.social webinar. More details below, or you can register here for free: us06web.zoom.us/webinar/regi... @activemotifusa.bsky.social

That is one way to get funding rates up, I guess. erc.europa.eu/news-events/...

Hands up if you love chromatin & structural biology 🙋‍♂️ On Friday April 24th we will be joined by @kjarmache.bsky.social from NYU for his webinar 'Chromatin-Modifying Complexes in Gene Activation and Silencing'. Register here: us06web.zoom.us/webinar/regi... @activemotifusa.bsky.social

Are you chromat-in or chromat-out? 🧬 Less than 2-weeks left to submit your abstract for this years @aicc-ireland.bsky.social symposium in @ucddublin.bsky.social ! We will be choosing talks & posters from these abstracts to present - with some fantastic prizes available. Registration link below 👇

Reminder about this exciting webinar from Karen Adelman on later today! 🍿 Registration details below 👇 @activemotifusa.bsky.social

Only 3 weeks left to get your abstract submitted for this years AICC symposium in @ucddublin.bsky.social Conway Institute! 🧬 We will be selecting speakers and posters from these abstracts with prizes up for grabs thanks to our generous sponsors! 🏆 allirelandchromatinconsortium.ie/annual-meeti...

Very excited for this webinar on Friday from Karen! Join us for the free @aicc-ireland.bsky.social webinar by following the registration details below.

⏰ Calling all chromatin aficionados! We we will be joined by @adelmanlab.bsky.social from @harvardmed.bsky.social for our March 27th webinar 📅 Karen will be sharing her groups work on 'Transcription & RNA Quality Control in Health & Disease' 😷🧬 Register here: us06web.zoom.us/webinar/regi...

1/ 🧵 In our new paper, we show that JARID2 and PALI1 mimic H3K27me3 to antagonise PRC2. www.cell.com/molecular-ce...

Webinar reminder ⏰ Next Friday join us for @brianstrahl.bsky.social - from @uncchapelhill.bsky.social - webinar on 'Chromatin at the Crossroads of Gene Regulation and Genome Integrity'. Don't miss out! See registration details below! us06web.zoom.us/webinar/regi... @activemotifusa.bsky.social

Please join us for this free @aicc-ireland.bsky.social event in @ucddublin.bsky.social, Dublin! Great chance to build the Irish nuclear and chromatin biology network and share your research! 🧬 allirelandchromatinconsortium.ie/annual-meeti...

We are excited to be bringing you two webinars from world leaders in epigenetics this month! 🧬 📅Feb 13th- Edith Heard from @crick.ac.uk 📅Feb 27th- @brianstrahl.bsky.social from @uncchapelhill.bsky.social Don't miss out! See registration details below! @activemotifusa.bsky.social

Just one week to go until Edith Heard will be joining us for the All-Ireland Chromatin Consortium webinar on 'The Epigenetic Dynamics of X Inactivation in Development and Disease' 🧬 Registration link: us06web.zoom.us/webinar/regi...

Webinar reminder ⏰ Our first All-Ireland Chromatin Consortium webinar of the year, presented by Dr Lucas Farnung, is coming up this Friday at 4pm 📅 . Free registration details below, as well as links to download our new webinar calendar 👇

Super line-up of chromatin, epigenetics and gene regulation speakers coming your way from @aicc-ireland.bsky.social over the next 5 months!

🚨 Multiple #PhD opportunities for lab or computational applicants. Do you want to understand the molecular basis of #epigenetic dysfunction in human disease? Come work with our group at the fantastic, collaborative @uoe-igc.bsky.social in a beautiful, liveable city. 🧵 1/4 Please repost 🙏

RESEARCH PAPER: Dominant-negative effects of Weaver syndrome-associated EZH2 variants By Deevy et al., Eric Conway and Adrian Bracken ➡️ https://genesdev.cshlp.org/content/39/21-22/1355.full Eric Conway Adrian Bracken #weaversyndrome #ezh2 #polycomb #mutation #congenitaldisorder #onthecover

We are delighted that @genesdev.bsky.social have selected our (w/ @adrianbracken.bsky.social) Weaver syndrome paper artwork as the November cover! This piece was made by my incredibly talented niece, Gina 'Dna Vinci' Ronan. @ucddublin.bsky.social @tcddublin.bsky.social @ucd-sbbs.bsky.social

Paul Nurse describing the main job of a PI (From ‘The Thinking Game’, 2024)

1/ 🚀 AEBP2 isn’t what we thought. You were told that AEBP2 promotes PRC2 activity on chromatin. We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity. 👉 surl.li/cgwqcq A thread 🧵

Second annual Conway/ Coughlan lab pumpkin carving competition this morning with plenty of coffee and treats to keep us going! Skills getting better every year. Can anyone spot the nucleosomes? @coughlan-lab.bsky.social @ucddublin.bsky.social @ucd-sbbs.bsky.social

Absolutely delighted to share our preprint, using functional genomics to uncover a novel dependency in lymphoma that can overcome resistance to targeted therapy. Grateful to co-first author @jamesnolan.bsky.social and co-senior authors @conwayer1.bsky.social and @adrianbracken.bsky.social see👇

🧵1/Exciting news in cancer epigenetics! Our latest research, "AEBP2-Directed H3K27me2 Defines a Specific Vulnerability in EZH2-mutant Lymphoma", is now available on www.biorxiv.org/content/10.1.... Here's a thread summarizing our findings!👇 #CancerResearch #Epigenetics #Chromatin #Lymphoma

Our very own Evan Matthews, from @coughlan-lab.bsky.social, will be running the Dublin Marathon this month in aid of the Irish Cancer Society! If you want to show Evan and the ICS your support you can donate through the link below! eventmaster.ie/fundraising/... @ucddublin.bsky.social 🏃💨

There's a super line up next March for the Keystone meeting in Geneva for anyone interested in chromatin and epigenetics! Not a bad spot for a Spring trip! 🧬👇🇨🇭 #KSEpigenetics26 #epigenetics #chromatin #KeystoneSymposia

We are looking for a student to continue our work on chromatin evolution: www.nature.com/articles/s41... www.biorxiv.org/content/10.1... The project with @seanamontgomery.bsky.social will focus on chromatin state readers across eukaryotes. More info: recruitment.crg.eu/content/jobs...

👏 Congrats to @conwayer1.bsky.social on a major @genesdev.bsky.social‬ publication! In collab with @adrianbracken.bsky.social @tcddublin.bsky.social & Dr Orla Deevy @ucdscience.bsky.social, the team showed how EZH2 mutations disrupt PRC2, driving Weaver syndrome🧬 📖 Read more here ▶️bit.ly/3HL0YiI

Delighted that our work on EZH2 dominant negativity in Weaver syndrome is now out in Genes & Development! This exciting work on chromatinopathies 🧬 was in collab with @adrianbracken.bsky.social and spearheaded by Orla Deevy. @ucddublin.bsky.social @ucd-sbbs.bsky.social www.ucd.ie/newsandopini...

Really excited to share the line up for this years @arrefoundation.bsky.social research symposium. It was a pleasure to contribute to putting the program together this year. Looking forward to seeing everyone in Boston in October! More details can be found here: asxlconference.org

Amazing new initiative with a seriously impressive budget (€2.25M to 3.25M) to attract researchers to Ireland! Would be great to get some more chromatin biologists here! 👀🧬

Great to enjoy the last of the Irish summer with a lab BBQ to celebrate paper acceptance 🎉 and individual grant/ travel/ poster prizes over the last few months! ☀️ 🍖 🍻 @coughlan-lab.bsky.social

I am looking for a new postdoc to join the lab. Interested in pluripotency, germ cells, and in investigating these in a genetically tractable cnidarian? Get in touch! We offer a long-term contract, excellent research environment, and a lovely city #Galway. www.urifranklab.org

Big congratulations to best poster and best talk award winners @samrustichelli.bsky.social (Diego Pasini lab,IEO) and Mike Rainey (Corrado Santocanale lab) @uniofgalway.bsky.social 🏆🏆

Looking back on a super day at the AICC symposium one week on 🤩 many thanks to @tcddublin.bsky.social micro department for hosting and to our sponsors @epicypher.bsky.social & @novogene-europe.bsky.social. Thanks to all attendees, we hope to see again in May next year🌞

New Novogene freebies 🥰 I am going to be at the All-Ireland Chromatin Consortium #AICC25 in Trinity College Dublin this Wednesday. @tcddublin.bsky.social Please come by and say hi, and pick up some of these new freebies. @aicc-ireland.bsky.social @novogene-europe.bsky.social

Only 5 days to go until our flagship event of the year!

🎉 Huge congrats to our 3 #PhD students ⭐Grace Ruddin ⭐ ⭐Rhys Orimaco⭐ ⭐Molly Davies⭐ who each won a prize for their presentations at yesterday’s SBBS Research Day 2025 🏆🧪 🔗 lnkd.in/e2-WFaug @ucdscience.bsky.social @ucdresearch.bsky.social @ucddublin.bsky.social #SBBSRD2025 #UCDResearch

Awesome to be able to share our work on PAX8 in high-grade serous ovarian cancer, super job @daviesmolly13.bsky.social! Thanks for the opportunity to share @gensocuk.bsky.social @ucd-sbbs.bsky.social @ucdresearch.bsky.social

We are very excited to launch the registration for our 2025 symposium on 'Chromatin, Epigenetics and Transcription' today! Join us at @tcddublin.bsky.social on May 28th for this event featuring keynote, new PI and PhD/postdoc talks and posters! allirelandchromatinconsortium.ie/annual-meeti...

🎉ENGAGE Finalist Spotlight! ⭐ 📢Introducing Finalist #4: Emma Doyle 🧬 🔬 Emma explains CRISPR gene editing and how it’s unlocking powerful discoveries in biomedical research 📅 Catch her live in UCD or online at 5pm Wed April 16👇 www.ucd.ie/sbbs/newsand... #AccessibleScience @conwayer1.bsky.social

🎉ENGAGE Finalist Spotlight!⭐ 📢Introducing Finalist #3: Molly Davies 🎗️ 🧬 Molly investigates how ovarian cancer rewires DNA structure—giving new insights into tumour behaviour🧫 📅 Don’t miss her talk at the ENGAGE Final, 5pm April 16 at UCD or online👇 www.ucd.ie/sbbs/newsand... #AccessibleScience

My group is hiring a new Postdoc to work on gene regulation and chromatin in Nematostella. Please RT! For more information see here: gahanlab.com tinyurl.com/34xke35d

Great opportunity for a post-doc to join the University of Galway in the research team of our committee member @jgahan.bsky.social!

We have a postdoc position in my group in collaboration with EMBL Rome; join us to make important discoveries in this exciting project. Please apply or share. hrwebapp.qub.ac.uk/tlive_webrec...

Just under 3 hours until this months @aicc-ireland.bsky.social webinar from Peter Lewis!