We are delighted that @genesdev.bsky.social have selected our (w/ @adrianbracken.bsky.social) Weaver syndrome paper artwork as the November cover! This piece was made by my incredibly talented niece, Gina 'Dna Vinci' Ronan. @ucddublin.bsky.social @tcddublin.bsky.social @ucd-sbbs.bsky.social

Paul Nurse describing the main job of a PI (From ‘The Thinking Game’, 2024)

1/ 🚀 AEBP2 isn’t what we thought. You were told that AEBP2 promotes PRC2 activity on chromatin. We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity. 👉 surl.li/cgwqcq A thread 🧵

Second annual Conway/ Coughlan lab pumpkin carving competition this morning with plenty of coffee and treats to keep us going! Skills getting better every year. Can anyone spot the nucleosomes? @coughlan-lab.bsky.social @ucddublin.bsky.social @ucd-sbbs.bsky.social

Absolutely delighted to share our preprint, using functional genomics to uncover a novel dependency in lymphoma that can overcome resistance to targeted therapy. Grateful to co-first author @jamesnolan.bsky.social and co-senior authors @conwayer1.bsky.social and @adrianbracken.bsky.social see👇

🧵1/Exciting news in cancer epigenetics! Our latest research, "AEBP2-Directed H3K27me2 Defines a Specific Vulnerability in EZH2-mutant Lymphoma", is now available on www.biorxiv.org/content/10.1.... Here's a thread summarizing our findings!👇 #CancerResearch #Epigenetics #Chromatin #Lymphoma

Our very own Evan Matthews, from @coughlan-lab.bsky.social, will be running the Dublin Marathon this month in aid of the Irish Cancer Society! If you want to show Evan and the ICS your support you can donate through the link below! eventmaster.ie/fundraising/... @ucddublin.bsky.social 🏃💨

There's a super line up next March for the Keystone meeting in Geneva for anyone interested in chromatin and epigenetics! Not a bad spot for a Spring trip! 🧬👇🇨🇭 #KSEpigenetics26 #epigenetics #chromatin #KeystoneSymposia

We are looking for a student to continue our work on chromatin evolution: www.nature.com/articles/s41... www.biorxiv.org/content/10.1... The project with @seanamontgomery.bsky.social will focus on chromatin state readers across eukaryotes. More info: recruitment.crg.eu/content/jobs...

👏 Congrats to @conwayer1.bsky.social on a major @genesdev.bsky.social‬ publication! In collab with @adrianbracken.bsky.social @tcddublin.bsky.social & Dr Orla Deevy @ucdscience.bsky.social, the team showed how EZH2 mutations disrupt PRC2, driving Weaver syndrome🧬 📖 Read more here ▶️bit.ly/3HL0YiI

Delighted that our work on EZH2 dominant negativity in Weaver syndrome is now out in Genes & Development! This exciting work on chromatinopathies 🧬 was in collab with @adrianbracken.bsky.social and spearheaded by Orla Deevy. @ucddublin.bsky.social @ucd-sbbs.bsky.social www.ucd.ie/newsandopini...

Really excited to share the line up for this years @arrefoundation.bsky.social research symposium. It was a pleasure to contribute to putting the program together this year. Looking forward to seeing everyone in Boston in October! More details can be found here: asxlconference.org

Amazing new initiative with a seriously impressive budget (€2.25M to 3.25M) to attract researchers to Ireland! Would be great to get some more chromatin biologists here! 👀🧬

Great to enjoy the last of the Irish summer with a lab BBQ to celebrate paper acceptance 🎉 and individual grant/ travel/ poster prizes over the last few months! ☀️ 🍖 🍻 @coughlan-lab.bsky.social

I am looking for a new postdoc to join the lab. Interested in pluripotency, germ cells, and in investigating these in a genetically tractable cnidarian? Get in touch! We offer a long-term contract, excellent research environment, and a lovely city #Galway. www.urifranklab.org

Big congratulations to best poster and best talk award winners @samrustichelli.bsky.social (Diego Pasini lab,IEO) and Mike Rainey (Corrado Santocanale lab) @uniofgalway.bsky.social 🏆🏆

Looking back on a super day at the AICC symposium one week on 🤩 many thanks to @tcddublin.bsky.social micro department for hosting and to our sponsors @epicypher.bsky.social & @novogene-europe.bsky.social. Thanks to all attendees, we hope to see again in May next year🌞

New Novogene freebies 🥰 I am going to be at the All-Ireland Chromatin Consortium #AICC25 in Trinity College Dublin this Wednesday. @tcddublin.bsky.social Please come by and say hi, and pick up some of these new freebies. @aicc-ireland.bsky.social @novogene-europe.bsky.social

Only 5 days to go until our flagship event of the year!

🎉 Huge congrats to our 3 #PhD students ⭐Grace Ruddin ⭐ ⭐Rhys Orimaco⭐ ⭐Molly Davies⭐ who each won a prize for their presentations at yesterday’s SBBS Research Day 2025 🏆🧪 🔗 lnkd.in/e2-WFaug @ucdscience.bsky.social @ucdresearch.bsky.social @ucddublin.bsky.social #SBBSRD2025 #UCDResearch

Awesome to be able to share our work on PAX8 in high-grade serous ovarian cancer, super job @daviesmolly13.bsky.social! Thanks for the opportunity to share @gensocuk.bsky.social @ucd-sbbs.bsky.social @ucdresearch.bsky.social

We are very excited to launch the registration for our 2025 symposium on 'Chromatin, Epigenetics and Transcription' today! Join us at @tcddublin.bsky.social on May 28th for this event featuring keynote, new PI and PhD/postdoc talks and posters! allirelandchromatinconsortium.ie/annual-meeti...

🎉ENGAGE Finalist Spotlight! ⭐ 📢Introducing Finalist #4: Emma Doyle 🧬 🔬 Emma explains CRISPR gene editing and how it’s unlocking powerful discoveries in biomedical research 📅 Catch her live in UCD or online at 5pm Wed April 16👇 www.ucd.ie/sbbs/newsand... #AccessibleScience @conwayer1.bsky.social

🎉ENGAGE Finalist Spotlight!⭐ 📢Introducing Finalist #3: Molly Davies 🎗️ 🧬 Molly investigates how ovarian cancer rewires DNA structure—giving new insights into tumour behaviour🧫 📅 Don’t miss her talk at the ENGAGE Final, 5pm April 16 at UCD or online👇 www.ucd.ie/sbbs/newsand... #AccessibleScience

My group is hiring a new Postdoc to work on gene regulation and chromatin in Nematostella. Please RT! For more information see here: gahanlab.com tinyurl.com/34xke35d

Great opportunity for a post-doc to join the University of Galway in the research team of our committee member @jgahan.bsky.social!

We have a postdoc position in my group in collaboration with EMBL Rome; join us to make important discoveries in this exciting project. Please apply or share. hrwebapp.qub.ac.uk/tlive_webrec...

Just under 3 hours until this months @aicc-ireland.bsky.social webinar from Peter Lewis!

Awesome to have two of the lab make it to the final of this @ucd-sbbs.bsky.social #scicomm initiative. 🧬 Now to bring home the 🏆 @daviesmolly13.bsky.social and Emma!

🧬🧪Exciting chromatin research conference hosted by @aicc-ireland.bsky.social in May! The deadline for poster/talk abstracts is April 28, see details in the post below.

A big thank you to our generous sponsors for this event- @epicypher.bsky.social, @activemotifusa.bsky.social and @novogene-europe.bsky.social

Really looking forward to this event, quickly becoming a highlight of the year- and venue is in very close proximity to the Pav! 👀

📣 We are advertising for a postdoc to join our team at the University of Edinburgh! Our lab studies gene regulatory mechanisms in development, and how genetic changes may impact these processes to alter development and shape human craniofacial form and function 🧬🧪

Looking forward to welcoming @peterlewislab.bsky.social from @uwmadison.bsky.social for our March webinar on 'Dissecting the Biochemical Complexes Governing Gene Silencing' on March 28th! Register here: us06web.zoom.us/webinar/regi... @activemotifusa.bsky.social

Anyone looking to Europe for research & interested in chromatin biology then we have opportunities in UCD, Ireland. Welcoming & diverse group & we would love to add thanksgiving to our seasonal celebrations! Postdoc: conwaychromatinlab.com/team PhD (MSc not required): www.coughlan-lab.com/team

Anyone looking for a PhD position in chromatin biology and gene regulation look no further! Great chance to join a new lab at the University of Exeter.

Anyone looking to Europe for research & interested in chromatin biology then we have opportunities in UCD, Ireland. Welcoming & diverse group & we would love to add thanksgiving to our seasonal celebrations! Postdoc: conwaychromatinlab.com/team PhD (MSc not required): www.coughlan-lab.com/team

Great chance to join our close collaborators here in UCD! If you are looking for a PhD position and are interested in cancer and/or chromatin biology here's your chance! @coughlan-lab.bsky.social

🚨🚨 New PhD position available in my research group @ucddublin.bsky.social ! If you are interested in enhancer biology, functional genomics and cancer get in touch! Position starts Sep 2025. More details at the link below. www.coughlan-lab.com/team Please share with anyone who may interested!

Our February webinar is coming up this Friday from @arnausebe.bsky.social at the @crg.eu. Join us for his talk on 'The origin and early evolution of animal regulatory genome architecture' Registration details below! @activemotifusa.bsky.social

PhD positions on yeast available in my lab in science-friendly Ireland! www.findaphd.com/phds/project...

🎉And we’re now on BlueSky!🎉 Launching with #ENGAGE2025 our school's public science comms event where PhD students showcase their cutting-edge research in a clear & accessible way🧬 📅 5pm Wed April 16 |📍UCD & Online Open to general public. Don't miss out! Learn more & register here👉 bit.ly/3EUekHj

Coming up this month on Feb 28th- we will be joined by @arnausebe.bsky.social from the @crg.eu for his webinar on 'The origin and early evolution of animal regulatory genome architecture'. Registration details here: us06web.zoom.us/webinar/regi... @activemotifusa.bsky.social

Happy international day of women and girls in science! Shout out to the amazing women in our lab working every day to better understand ovarian cancer, leukemia and Bohring-Opitz syndrome! 👩‍🔬🧬

First webinar of the year for the All-Ireland Chromatin Consortium coming up this Friday! Registration details for Yael Davids webinar below. @activemotifusa.bsky.social

2-year computational postdoc position available to join our growing team to work on super-enhancers & transcription factors in AML @ucddublin.bsky.social. This project will use patient biopsies to identify 'epigenomic' sensitivities for this devastating cancer. conwaychromatinlab.com/team

Great chance to join our close collaborators here in UCD! If you are looking for a PhD position and are interested in cancer and/or chromatin biology here's your chance! @coughlan-lab.bsky.social

First webinar of the year from Dr Yael David is coming up on January 31st! 🧬🔬 Registration details below 👇

Please see 🧵by @evhealy.bsky.social about our new paper exploring the role of PRC1 and PRC2 in non-dividing cells 👇