This Valentine’s Day, don’t go it alone. 💕 Fiber-seq custom services pair you with an EpiCypher expert for hands-on assay setup, best practices, and bioinformatics support—so you get high-quality data with confidence. 👉 https://www.epicypher.com/services/cutana-fiber-seq-assay-services/

We recently welcomed Dr. Steve Henikoff to EpiCypher for a seminar on “Epigenomic profiling for personalized medicine.” From chromatin mapping advances to thoughtful team discussions, it was an energizing visit. Always grateful to learn alongside leaders in #Epigenetics 🔬

It’s International Day of Women and Girls in Science. 🔬 We’re celebrating the women whose research, mentorship, and leadership continue to move science forward and open doors for the next generation. #WomenInScience

New paper out in ACS Central Science from EpiCypher + the Kelleher lab: “Direct Readout of Multivalent Chromatin Reader-Nucleosome Interactions by Nuc-MS” (Lee et al., 2026). Love seeing intact nucleosomes used to capture multivalent reader behavior, plus the role of dNucs™ and Captify™🧬

Using EpiCypher reagents for DIY CUT&RUN or CUT&Tag? 🧪 Our updated DIY protocols are live with clearer handling guidance, optimized bead ratios, and the CUTANA™ Wash Buffer Enhancer Set to help reduce variability, especially for nuclei inputs. Take a look and tell us how it works in your lab.

Recently, our CSO Michael-Christopher Keogh, PhD shared a talk at New England Biolabs on multi-omic views of chromatin function. Thanks to NEB for hosting and for the ongoing scientific collaboration. 🧬🔬 #Epigenetics #Chromatin

We've got two exciting chromatin talks coming up on Wednesday next week: @epijenatics.bsky.social from @jbuenrostro.bsky.social's lab and @ambystoma22.bsky.social! register and join us: us06web.zoom.us/webinar/regi...

On #WorldCancerDay, we reflect on the impact of cancer and the progress we’re making together. EpiCypher is proud to support labs decoding chromatin dynamics in cancer—because understanding epigenetics changes the game. 🧬 Let’s keep pushing forward.

Punxsutawney Phil says winter’s sticking around ❄ But so are we—in the lab, at the bench, decoding chromatin one nucleosome at a time. What’s your go-to winter epigenetics workflow? #Epigenetics

Attention: Researchers in genomics, epigenetics, and single-cell biology! Watch our on-demand webinar to explore how Paired-Damage-seq integrates DNA damage mapping with transcriptomics to reveal cell-type-specific genome instability. Watch now 👉 https://ow.ly/kAUg50Y4Seu

Last Chance To Register! Learn how Paired-Damage-seq links DNA damage with transcriptomics in our webinar with Epigenome Technologies. Register Here: 👉 https://app.livestorm.co/epicypher/single-cell-dna-damage-analysis-reveals-selective-genome-vulnerability

See EpiCypher at the Festival of Genomics & Biodata (London), Jan 28 - 29, 2026. Poster: “Fiber-seq connects genetic variation to epigenomic function on single DNA molecules”. Not attending? Download the poster: https://explore.epicypher.com/posters/LRS-emily/FOG2026 #Epigenomics #Genomics

EpiCypher’s at #KeystoneSymposia this week! 🧬 Poster #2001: Fiber-seq connects genetic variation to epigenomic function on single DNA molecules 📍 Jan 28, 7:30 PM ET | Cary, NC Missed it in person? Download the full poster: https://explore.epicypher.com/posters/Keystone-Jan2026/fiber-seq

🥁 #FragileNucleosome is back on Jan 28! We are very excited to host @au-ho-yu.bsky.social and @gcloner.bsky.social as our first speakers of 2026! 📋Please don't forget to register for our 2026 seminar series: us06web.zoom.us/webinar/regi...

How can you profile chromatin accessibility, DNA methylation, and protein footprints in a single assay? 🔗 Read more: https://www.epicypher.com/resources/blog/fiber-seq-101/ #Epigenomics #Chromatin #ATACseq #Multiomics #Fiberseq #EpiCypher

Running into issues with CUT&RUN, CUT&Tag, or Fiber-seq? 🧬 You’re not alone. Our Tech Support Center has in-depth guides, from antibody selection to CUTANA™ Cloud analysis. Explore the help hub 👉 support.epicypher.com #Epigenetics #ChromatinMapping

Genomics & single-cell researchers—expand your toolkit. 👨‍🔬Learn how Paired-Damage-seq links DNA damage with transcriptomics in our webinar with Epigenome Technologies. Register Here: 👉 https://app.livestorm.co/epicypher/single-cell-dna-damage-analysis-reveals-selective-genome-vulnerability

CUTANA™ Cloud — the easiest way to analyze CUT&RUN and CUT&Tag data. No coding needed. Upload, analyze, and discover with just a few clicks. ☁️ www.epicypher.com/CUTANA-Cloud

A wonderful collaboration between Jess Tyler lab, @epicypher.bsky.social, @gcloner.bsky.social, James Kadonaga and our lab at PSU. In this article, we provide the significance of the nucleosome acidic patch.  doi.org/10.64898/202...

Congrats to the 2025 PacBio Epigenetics SMRT Grant awardees! 🧬🎊 Excited to see their work with Fiber-seq in epigenomics. 🔬🧪 Learn more here: https://www.pacb.com/blog/2025-epigenetics-smrt-grant-awardees/

PAG 33 wrap-up ✅ Thanks to everyone who kept booth 329 busy and shared great questions about Fiber-seq and beyond. Also, shoutout to everyone who stopped by Keith and Hannah’s posters. What was your favorite session or takeaway from PAG this year? 🧬🔬 #PAG2026 #Epigenomics

Genomics & single-cell researchers—expand your toolkit. 👨‍🔬Learn how Paired-Damage-seq links DNA damage with transcriptomics in our webinar with Epigenome Technologies. Register Here: 👉 https://app.livestorm.co/epicypher/single-cell-dna-damage-analysis-reveals-selective-genome-vulnerability

Great poster session at #PAG33. We were proud to have two EpiCypher presenters on the floor. Thanks to everyone who stopped by! Download the posters here: • Keith: https://explore.epicypher.com/posters/LRS-keith/pag2025 • Hannah: https://explore.epicypher.com/posters/DNAme/pag2025#PAG33

Fiber-seq just earned Tech of the Month in Trends in Plant Science! It overlays chromatin accessibility, methylation, & protein binding on long DNA fibers, unlocking repeat-rich plant regions. Come chat if you’re at #PAG33! 🔗 https://www.cell.com/trends/plant-science/abstract/S1360-1385(25)00358-9

Day 1 at #PAG2026 is done ✅ Thanks to everyone who stopped by (and kept our booth busy!) to talk Fiber-seq and beyond. Come see us at booth 329 today, and be sure to catch Keith and Hannah’s posters in the poster sessions. What are you most excited to see at PAG today? 🔬

PAG 33 friends: Hannah Devens, PhD presents poster P343 on direct multiomic mapping of DNA methylation and chromatin features in agricultural epigenetics (Jan 12, 3PM to 4:30 PM). Poster download: https://explore.epicypher.com/posters/DNAme/pag2025

🧬 How can you study DNA damage and gene expression in the same single cell? Join our upcoming webinar with Epigenome Technologies to learn how Paired-Damage-seq reveals cell-type-specific genome instability and disease-relevant insights. Learn More & Register Today! 👉 https://ow.ly/Hjtz50XU2aW

PAG 33 folks: catch Keith Maier, PhD, poster P324 on multiomic long-read sequencing of chromatin state and genetic variation (Jan 12, 10:00 AM to 11:30 AM). Not onsite? Poster download: https://explore.epicypher.com/posters/LRS-keith/pag2025 What multiomic question are you chasing right now? 🧬🔬

Coming to #PAG2026? Drop by booth 329 to chat with EpiCypher about Fiber-seq – a powerful new way to see chromatin architecture at the single-molecule level. Ask us how it works (and get some swag). #Fiberseq #Chromatin

Happy New Year from all of us at EpiCypher! 🧬 Here’s to fresh experiments, better data, and bold chromatin discoveries in 2026. We’re excited to keep advancing epigenetics together. #Epigenetics #ChromatinBiology #LabLife

Science travel plans? 🧬 We’ve refreshed our Conference Page with 2026 booths, posters & symposia. Start planning here: https://www.epicypher.com/resources/epigenetics-conferences/ #Epigenetics #Chromatin

Looking to boost your drug discovery & development pipelines? Next-generation chromatin profiling can help uncover drug mechanism of action and discover biomarkers. Learn more: https://www.epicypher.com/resources/blog/looking-to-boost-your-drug-discovery-and-development-pipelines-heres-how

Cheers to a season of rest and discovery 🎉 We’re closing Dec 25 through Jan 1 for the holiday season and will be back Jan 2. Thanks for growing the field with us this year! #Epigenetics #LabLife

Understanding a drug’s mechanism of action is critical for streamlining development and improving clinical success. Dave Lahr, PhD, shares how Foghorn Therapeutics uses EpiCypher's CUT&RUN Services to uncover drug MOA and accelerate development. Read here: https://ow.ly/PCQW50XGva5

Fiber-seq: one giant leap for sequencing 🪐 A new Fierce Biotech whitepaper breaks down Fiber-seq’s origins, adoption, and the insights now within reach. 📄 Read the whitepaper: https://fb-resources.fiercebiotech.com/free/w_defa9801/?pk=LS-WP-EpiCypher-112525-listing

🚨Holiday Shipping PSA🚨 Our last ship date for 2025 is Dec 22 Shipping resumes Jan 5, 2026 Place your orders soon—we’re here to help with planning 📦 #Epigenetics #ChromatinTools

When your data quality matters, small workflow improvements can make a big difference. That’s why we’ve released CUTANA™ CUT&RUN Kit Version 6 — with updates designed to improve reproducibility and streamline handling. See what’s new in v6: https://www.epicypher.com/product/cutana-chic-cutrun-kit/

Cheers to another year of science, teamwork, and innovation 🧬 Our 2025 holiday party reminded us how lucky we are to work with such an amazing group of scientists. Thanks for making this journey meaningful. #Epigenetics #LabLife

Researchers face a tough choice for DNA methylation sequencing: expensive and destructive bisulfite-seq, or limited insights from arrays, panels, and RRBS. Read our blog to learn how meCUT&RUN avoids these pitfalls: https://www.epicypher.com/resources/blog/dna-methylation-profiling-mecutrun/

💡 The Scientist spotlights how long-read sequencing is reshaping research of complex diseases. In a Q&A, Dr. Bryan Venters of EpiCypher explains how Fiber-seq technology is advancing the field. 📄 https://www.the-scientist.com/advances-in-long-read-sequencing-boost-epigenomic-research-73818

🧬🎉Join us on Dec 17th for our last session of 2025! 🎉🧬Two fantastic talks on transcriptional regulation: 🔬JB Lalanne on developmental enhancers (and starting a lab in 2025?) 🔬 @rberrens.bsky.social on transposable elements in development 📋Register here: us06web.zoom.us/webinar/regi...

Couldn’t make it live? 🎥 The replay is now available! Watch Zach Freeman, DVM, PhD & Emily Madden, PhD discuss how Fiber-seq + PureTarget™ uncover hidden transgene alterations. 👉 https://app.livestorm.co/epicypher/combining-fiber-seq-and-puretarget #Epigenetics #WebinarReplay

CUTANA™ Cloud — the easiest way to analyze CUT&RUN and CUT&Tag data. No coding needed. Upload, analyze, and discover with just a few clicks. ☁️ www.epicypher.com/CUTANA-Cloud

One experiment. Multiomic insights. CUTANA™ Fiber-seq captures chromatin accessibility, protein footprints, DNA methylation, and more in ONE assay—saving time, samples, & budget. Interested in Fiber-seq Services? Start here: https://www.epicypher.com/services/cutana-fiber-seq-assay-services/

🎥 The webinar recording is now live! Catch up on insights from Zach Freeman, DVM, PhD and Emily Madden, PhD on how Fiber-seq + PureTarget™ reveal hidden integration and expression issues. Replay here: https://app.livestorm.co/epicypher/combining-fiber-seq-and-puretarget #Epigenetics #Chromatin

It’s webinar day! 🎉 Join us at 3PM EST for a deep dive into Fiber-seq + PureTarget™ with Zach Freeman, DVM, PhD and Emily Madden, PhD. Still time to register: https://app.livestorm.co/epicypher/combining-fiber-seq-and-puretarget #Epigenetics #GenomeEngineering

The wait is almost over ⏳ Our webinar on Fiber-seq + PureTarget™ goes live tomorrow! Zach Freeman, DVM, PhD and Emily Madden, PhD will share new insights + tips for transgene analysis. Grab your spot: https://app.livestorm.co/epicypher/combining-fiber-seq-and-puretarget #Epigenetics #CRISPR

🔔Join us next Wednesday for #FragileNucleosome! 2 fantastic talks on chromatin regulation:🔬 @mariamafau.bsky.social on ZIC2's dual role in neural induction 🔬 @jhenninger.bsky.social on how RNA-binding proteins drive transcription 📋Register here for the entire series: us06web.zoom.us/webinar/regi...

Grateful for every scientist mapping the epigenome, sharing data, or troubleshooting at midnight. Whether you’re celebrating Thanksgiving or not, thanks for being part of our community 🧬💡 #Epigenetics #ScienceLife

🚨 One-week countdown! Don’t miss this free webinar on Fiber-seq + PureTarget™ for uncovering transgene integration and regulation issues. 📆 Dec 3 @ 3PM EST – sign up here: https://app.livestorm.co/epicypher/combining-fiber-seq-and-puretarget #Epigenetics #CRISPR