This paper marks our trilogy on H2AK119Ub mechanisms. We have now characterized: PRC1 (the Writer), BAP1/ASXL1 (the Eraser) and DNMT3A1 (the Reader) of H2AK119Ub in collaboration with the amazing labs of Chao Lu, JP Armache, Diego Pasini, Mike Keogh and the Epicypher and Evgeny Nudler.
10 months ago