Researchers have built a machine learning framework called MULTI-evolve that predicts how multiple amino acid changes interact — allowing scientists to identify high-performing proteins in just one round of experiments. https://www.sciencenews.org/article/machine-learning-better-proteins

Study shows SRS is worth it with 5-20 metastases. Stereotactic Radiation vs Hippocampal-Avoidance Whole Brain Radiation url: jamanetwork.com/journals/jam...

Disruptions in Medicare Advantage Coverage in 2026 url: jamanetwork.com/journals/jam...

Bucks County moves forward with backlash to Trump’s insane “Restoring Truth and Sanity to American History” executive order. Bucks Joins Regional Lawsuit Seeking To Restore Slavery Exhibit [in Philadelphia] patch.com/pennsylvania...

Today 2/6 at 4pm: Friday Cancer Center Seminar Series @ucsanfrancisco.bsky.social | Isaac Chan, MD, PhD from UT Southwestern Medical Center presents "Using innate barriers to treat metastatic breast cancer" Hosted by @andreigoga.bsky.social Info: cancer.ucsf.edu/seminars

A second and last genomic assay showed a BRCA1 mutation but tested negative in germline. That was several years ago. ascopubs.org/doi/abs/10.1...

Potential shift in clinical practice. Used this method for metastatic breast cancer in ‘07/‘08 for single 1 cm lung mets (brain met treated w/craniotomy/IMRT) Oligometastatic prostate cancer: time to integrate metastasis-directed therapy - The Lancet Oncology www.thelancet.com/journals/lan...

Antimicrobial resistance contributes to an estimated 4.71m deaths per year. This week, Crick group leader Ester Morreale hosted researchers from across Europe as part of a new initiative, END2AMR, which aims to tackle difficult-to-treat bacterial infections. www.crick.ac.uk/news/2026-01...

ASCENT-04/KEYNOTE-D19: In patients with previously untreated, PD-L1–positive, advanced triple-negative breast cancer, sacituzumab govitecan + pembrolizumab led to significantly longer progression-free survival than chemotherapy + pembrolizumab. Full phase 3 trial results: nej.md/49MoXaW

🚨 New American Cancer Society study: States that limit/don’t allow short-term health plans saw delays in timely cancer treatment initiation after diagnosis. Health insurance is a major factor in survival. #CancerCare ✍️ Jingxuan Zhao, PhD 🔗 https://ow.ly/kPMk50Y4UpZ

In patients with atrial fibrillation after successful ablation, rivaroxaban therapy did not lead to a significantly lower incidence of a composite of stroke, systemic embolism, or new covert embolic stroke than aspirin therapy. Full OCEAN trial results and Research Summary: nej.md/3LsRJ86

#ColorectalCancer is now the leading cause of cancer death in females and males younger than 50 years combined in the US, surpassing other cancer types over the past three decades. ️ 📽️ Watch the video and read the full article: ja.ma/4pRCZOH

The golden age of global health assistance, defined by a huge influx of resources and a centering of health progress, is over. Great risks lie ahead—but also powerful opportunities to build new, more sustainable systems, as I write in @sciencepolitics.bsky.social. sciencepolitics.org/2026/01/23/t...

New research at MSK shows how dormant #metastatic cancer cells prevent the immune system from eliminating them by changing their shape. The findings illuminate how cancer cells physically adapt to survive. Learn more ⬇️

These 103 abstracts spotlight innovative, real-world solutions to close gaps in cancer care, from addressing racial and genomic disparities to expanding access through telehealth, AI, and implementation science: buff.ly/WvquNQG

👍🏼👍🏼👍🏼👍🏼👍🏼👍🏼👍🏼👍🏼👍🏼👍🏼 #bcsm #mbc #oligometastatic

Today, we honor Dr. King’s legacy of justice, equity, and service. As a National Day of Service, it invites us to learn, reflect, and serve our communities. Learn more from The King Center: https://thekingcenter.org/about-tkc/

This #MLKDay, we reflect on the persistent health disparities in cancer affecting underserved communities. Join a passionate group of national leaders, including cancer care clinicians, patient advocates and policymakers to tackle cancer disparities #SCHD26: buff.ly/dLicRDO #HealthEquity #CancerCare

Our department is hiring!!! If you have research interests in cancer-focused bioinformatics and computational biology, apply to join us in the Department of Cancer & Cellular Biology at Temple University Lewis Katz School of Medicine👇

Canada's new front-of-package labels are a win for public health. Evidence-based warning symbols on foods high in sodium, sugar and fat help consumers make informed choices—and push manufacturers to reformulate unhealthy products.

Be informed about cardiac toxicity related to systemic treatment in oncology. jamanetwork.com/journals/jam...

Results show that the combo significantly improves PFS in people with advanced NSCLC. onlinelibrary.wiley.com/doi/10.1111/...

Roughly three-quarters reported encountering misinformation, but there was no clinically significant association with fear of recurrence. #bcsm jamanetwork.com/journals/jam...

Happy New Year to all our followers. Mark your calendars for our first meeting of 2026, next Tuesday, with @linda-e-carlson.bsky.social and Sarah Bokovitz. DM for link and to be added to our mailing list. @realbowtiedoc.bsky.social @darcyburbage.bsky.social @ascocancer.bsky.social #pallsky

@crisbergerot.bsky.social @tingtingzhang.bsky.social @fionnualacrowley.bsky.social @ericroeland.bsky.social @mazietsangmd.bsky.social @joanmancusombc.bsky.social @coffeemommy.bsky.social @jillfeldman4.bsky.social

Scientists study why some people get Grades 3/4 toxicities from docetaxel. #bcsm ascopubs.org/doi/10.1200/...

Diagnostic performance of MRI in predicting pathological response in patients with triple-negative breast carcinomas undergoing neoadjuvant chemotherapy and immunotherapy link.springer.com/article/10.1...

Racial and ethnic differences persist in breast cancer. academic.oup.com/jncics/advan...

www.modernpathology.org/article/S089... Excellent @CancerResrch project w/top scientists to develop a digital HER2 assay w/inclusion of low/ultra-low. TY for including me and hearing comments about potential impact of diversity-no data available and noted as a limitation. @nlinmd @stolaney1 …

Applications to our 2026 Summer Student Training Programme are now open. We’re looking for undergrad students to join us for nine weeks this summer. See the projects on offer and check the participation eligibility requirements on our website. ⬇️ www.crick.ac.uk/careers-and-...

Lung cancer patients who received an mRNA COVID-19 vaccine within a few months of immunotherapy lived nearly twice as long as unvaccinated patients. https://www.sciencenews.org/article/cancer-immunotherapy-mrna-covid-vaccines

Important to see the acknowledgement of cancer dormancy & that top journals continue to highlight & publish on this topic. This problem is now studied in major Institutions worldwide. Congrats to all who work in this space! It is making & will make a difference! www.nature.com/articles/d41...

Lab-grown lung models have traditionally been grown from a mixture of cells, making it hard to tell how a disease or treatment will affect an individual person. These new models by @maxgg.bsky.social’s team and AlveoliX are grown from a single person’s stem cells ⤵️ www.crick.ac.uk/news/2026-01...

Amid federal funding cuts- and often controversial changes in guidance, 15 state and territorial leaders have come together to create the Governor’s Public Health Alliance. Here’s what to know about the new coalition. ja.ma/4smyVbH

Researchers at the Crick have uncovered how certain proteins that become exposed on dying tumour cells can be detected by the immune system, alerting it to the cancer’s presence and prompting an immune response. www.crick.ac.uk/news/2025-12...

New research adds to growing evidence that the nervous system plays a role in cancer growth. https://www.sciencenews.org/article/lung-cancer-brain-neuron

Makes a difference. A Lay Health Worker–Led Symptom Intervention and Acute Care Use in Older Adults With Cancer url: jamanetwork.com/journals/jam...

Radiotherapy With a 12-Gene Expression Assay for Ductal Carcinoma In Situ url: jamanetwork.com/journals/jam... #DCIS

Immune Checkpoint Inhibitor–Induced Diabetes Across Trials That Included PD-1 or PD-L1 Agents url: jamanetwork.com/journals/jam...

A 🆕 ACC Scientific Statement on the management of #cvPAD in adults w/ diabetes adds context to the 2024 ACC/AHA Lower Extremity PAD Guideline & "emphasizes a modern, evidence-based approach to care" starting w/ screening & advancing through treatment. More: 🔗 https://bit.ly/3YxYJDU #CardioSky

Natural daylight during office hours improves glucose control and whole-body substrate metabolism "Natural daylight exposure has a positive metabolic impact on individuals with type 2 diabetes and could support the treatment of metabolic diseases." www.cell.com/cell-metabol...

ICYMI: Watch Joseph A. Sparano, MD, FACP discuss initial findings from a public-private partnership between ECOG-ACRIN & Caris Life Sciences to improve recurrence risk assessment in early-stage #BreastCancer using #ArtificialIntelligence. Video via MedPage Today: bit.ly/48R3uNN #bcsm #AI #SABCS25

Inspired by a @nejm.org piece by Drs Brian Garibaldi and Steven Russell, I add my two cents on the physical examination. Because limitations notwithstanding, it still matters. blogs.nejm.org/hiv-id-obser...