Alexandra Dallaire
@alexdallaire.bsky.social
📤 188
📥 237
📝 35
Symbiotic fungi, genomes and transposons 🍄🧬 🇨🇦 → 🇬🇧 → 🇯🇵
reposted by
Alexandra Dallaire
Alejandro Montenegro
9 months ago
"The only kind of thinking that matters in science is structured thinking. The only way to give structure and substance to your thoughts is to write them down. Writing. Is. Thinking." Thinking about this in the context of AI tools....
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An open letter to graduate students and other procrastinators: it’s time to write - Nature Biotechnology
Nature Biotechnology - An open letter to graduate students and other procrastinators: it’s time to write
https://www.nature.com/articles/s41587-025-02584-1
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Alexandra Dallaire
Human Frontier Science Program
12 days ago
Attention scientists from all over the world🙃 The Call for Letters of Intent for
#HFSPResearchGrants
2027 is now open! 🧪 Get your international & interdisciplinary team. It's time to put your bold research idea into practice! 🔗https://bit.ly/48VsGCG 📅 15 Dec 2025–26 Mar 2026
#sts
#LifeSciences
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🌱 Why mutate when you can epimutate? A nice perspective on plants by
@thanvisrikant.bsky.social
&
@hajkdrost.bsky.social
add a skeleton here at some point
15 days ago
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Absolutely gorgeous microscopy and time-lapse imaging on this plant-mutualist-pathogen system! Insane in the membrane 🎶 Well done
@alexguyon.bsky.social
@dromius.bsky.social
and colleagues!
add a skeleton here at some point
16 days ago
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Alexandra Dallaire
Hagen Blix
about 1 month ago
In applying AI to material science, biology, etc, capitalism is trying to shed science. The point is to substitute the engineering of a machine that can generate what science has hitherto done, but without having people know things. Knowledge ultimately residing in private property is the dream.
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Jeff Bezos Creates A.I. Start-Up Where He Will Be Co-Chief Executive
https://www.nytimes.com/2025/11/17/technology/bezos-project-prometheus.html
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A phase oscillator model of cell cycles reveals nuclear density control in a branched fungal network
doi.org/10.1101/2025...
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A phase oscillator model of cell cycles reveals nuclear density control in a branched fungal network
Multinucleate cells are widespread in biology, from human skeletal muscle and placenta to many filamentous fungi, yet their basic cell biology remains poorly understood. Maintaining an appropriate nuc...
https://doi.org/10.1101/2025.11.26.690822
19 days ago
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Alexandra Dallaire
Cameron Thrash
24 days ago
Dated gene duplications elucidate the evolutionary assembly of eukaryotes
www.nature.com/articles/s41...
#jcampubs
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Dated gene duplications elucidate the evolutionary assembly of eukaryotes - Nature
Analysis of eukaryotic gene sequences using a relaxed molecular clock methodology indicate that eukaryotes emerged 3.0–2.25 billion years ago as a result of mitochondrial endosymbiosis with complex ar...
https://www.nature.com/articles/s41586-025-09808-z
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Alexandra Dallaire
Plantae.org
about 1 month ago
Plant Science Research Weekly -- How parasitic plants avoid being parasitized (Science)
@shirasulab.bsky.social
(Summary by Mary Williams
@PlantTeaching.bsky.social
)
buff.ly/KEgzFe5
#PlantaePSRW
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How parasitic plants avoid being parasitized | Plantae
It’s not too difficult to envision how a plant recognizes something very different from itself, like a bacterium, oomycete, or fungus. It’s a bit less obvious how a plant recognizes another plant as…
https://buff.ly/KEgzFe5
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Alexandra Dallaire
New Phytologist
about 1 month ago
New light on old stones: a fossil
#fungus
in
#symbiosis
with one of the oldest known land plants
@chistinesd.bsky.social
, et al.
nph.onlinelibrary.wiley.com/doi/10.1111/...
@dromius.bsky.social
@ffercoq.bsky.social
#PlantScience
Summary also available in French and Spanish.
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Alexandra Dallaire
Sarah Dellière
about 1 month ago
🔥 At conferences, who asks the questions shapes who gets seen. Across 24 ID&CM meetings, women were 55% of delegates but asked 36% of questions. 💬 When women moderate or speak first, others follow. Let’s change the pattern
bit.ly/47VL0eH
🙏
@maudsalmona.bsky.social
& MicroID EmpowHERment consortium
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Alexandra Dallaire
Toby Baril
about 2 months ago
TEs aren’t just genomic parasites, they’re also engines of genomic novelty. Our new study with ~2,000 Z. tritici genomes shows repeated TE mobilization waves during global expansion. With
@danielcroll.bsky.social
&
@guidopuccetti.bsky.social
🧬
www.nature.com/articles/s41...
#TEworldwide
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Historic transposon mobilisation waves create distinct pools of adaptive variants in a major crop pathogen - Nature Communications
In this study, the authors analysed a large genomic dataset to trace how jumping genes shaped the global spread of a major wheat pathogen and reveal bursts of activity over decades that drove adaptati...
https://www.nature.com/articles/s41467-025-64944-4
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Alexandra Dallaire
Sebastian Schornack
about 2 months ago
Plz RP. Come join us at
@slcuplants.bsky.social
@cam.ac.uk
to study effector-targeted plant processes impacting plant cell biology and development.
www.cam.ac.uk/jobs/post-do...
www.schornacklab.net
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Alexandra Dallaire
Benjamin Buchfink
2 months ago
DIAMOND v2.1.15 now supports all taxonomy features for BLAST databases, and support for using BLAST databases has also been added to the Bioconda version
github.com/bbuchfink/di...
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GitHub - bbuchfink/diamond: Accelerated BLAST compatible local sequence aligner.
Accelerated BLAST compatible local sequence aligner. - bbuchfink/diamond
https://github.com/bbuchfink/diamond
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Alexandra Dallaire
Vasilis Kokkoris
about 2 months ago
I had such fun thinking, reading and writing this Tansley Review on
#arbuscular
#mycorrhizal
#fungal
mycelia. We need a more fungal-centric view to better understand not only the AM fungi, but also their many ecological roles.
@newphyt.bsky.social
🔗
nph.onlinelibrary.wiley.com/share/DHGB3S...
.
add a skeleton here at some point
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Alexandra Dallaire
Institut Jacques Monod
2 months ago
#JobOffer
💼 Un poste susceptible d’être vacant de Professeur en stabilité des génomes devrait s’ouvrir pour la rentrée 2026 au sein de l’Institut Jacques Monod ➡️ Informations concernant ce poste et la procédure de candidature 🔗
www.ijm.fr/poste-de-pro...
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Serial innovations, HGT and gene loss led to the formation of the replisome of the eukaryotic ancestor
add a skeleton here at some point
2 months ago
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Alexandra Dallaire
PLOS Biology
2 months ago
Fungal
#GenomeSize
variation is largely driven by TEs & lineage-specific genome defenses.
@tbadet.bsky.social
&
@danielcroll.bsky.social
show that presence/absence of RIP mutation systems influences
#genome
architecture, identifying a likely novel defense mechanism
@plosbiology.org
🧪
plos.io/4hcC5tx
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🇨🇦 My department is recruiting a new tenure-track professor! If you do computational work on microbes and can teach in French reasonably well, please consider applying! Dry-wet lab hybrids also welcome.
www.rh.ulaval.ca/emplois-disp...
@ulaval.ca
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Tenure-Track Faculty Position in Omics Data Analysis in the Field of Microbial Systems Biology | Ressources humaines | Université Laval
https://www.rh.ulaval.ca/emplois-disponibles/corps-professoral/professeures-et-professeurs/HCM/10478
3 months ago
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Alexandra Dallaire
Mia Levine
3 months ago
Check out this new Levine-Lampson collaboration, led by the talented Hyuk-Joon Jeon. We explored the consequences of inheriting long telomeres from dad and short telomeres from mom. Or the reciprocal. Turns out, parent-of-origin matters (in mice, at least).
authors.elsevier.com/c/1loW-3QW8S...
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https://authors.elsevier.com/c/1loW-3QW8SA47k
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Alexandra Dallaire
Lukas Fiedler
3 months ago
Previously on BioRxiv, and now a final version of our paper is out! What a great lesson in plant self-organization: Auxin targets its own transporter through a cell-surface kinase complex in a positive feedback loop
www.cell.com/cell/fulltex...
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ABP1/ABL3-TMK1 cell-surface auxin signaling targets PIN2-mediated auxin fluxes for root gravitropism
In gravistimulated roots, gravity perception in the columella redirects the flow of the plant hormone auxin toward the lower root side, where it inhibits cell elongation for downward root bending. Thi...
https://www.cell.com/cell/fulltext/S0092-8674(25)00981-X
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Alexandra Dallaire
Héctor Montero
3 months ago
Learn about loss and retention of arbuscular mycorrhizal symbiosis in carnivorous plants in our latest publication in
@newphyt.bsky.social
!
nph.onlinelibrary.wiley.com/doi/10.1111/...
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Alexandra Dallaire
Nick Talbot
3 months ago
The great Claudio Scazzocchio- fungal geneticist and polymath - giving keynote first talk in Chania - on the evolution of nitrogen utilization in eukaryotes
#IFBC25
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Alexandra Dallaire
Frances Pitsillides
3 months ago
Very excited to share that my first 1st author publication is available at the journal of
#NewPhytologist
! Congratulations to the entire team that worked on this project including the
#KewFungarium
Team. 👏 🍄🟫 If you are interested in the topic, feel free to read it here:
doi.org/10.1111/nph....
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Whole genome sequencing of historical specimens from the world's largest fungal collection yields high‐quality assemblies
High-throughput molecular studies of museum specimens (museomics) have great potential in biodiversity research, but fungal historical collections have scarcely been examined, leading to no comprehe...
https://doi.org/10.1111/nph.70472
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Alexandra Dallaire
Christian Landry
4 months ago
Really excited to share our latest paper led by
@simonaube.bsky.social
. Fascinating results examining whether regulatory mutations can lead to adaptation as fast as coding mutations do.
#mevosky
#evobio
#evoSky
www.biorxiv.org/content/10.1...
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Adaptation is less accessible through mutations in promoters than in coding sequences when large effect sizes are needed
Mutations within promoters and coding sequences are both involved in adaptation, but their relative contributions remain to be compared directly. Using the fungal enzyme cytosine deaminase, we examine...
https://www.biorxiv.org/content/10.1101/2025.09.09.675213v1
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Alexandra Dallaire
Navin B. Ramakrishna
4 months ago
Excited to share our Review on human PGC development covering the latest in vivo observations & in vitro developments, esp. in the last 5 years. Have a read!
journals.biologists.com/dev/article/...
From:
@astar-gis.bsky.social
@ki.se
Warwick University,
@gurdoninstitute.bsky.social
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Emerging principles and models of human primordial germ cell development
Summary: This Review examines recent insights into early human germ cell development and how these regulatory principles guide stem cell-derived models aiming to reconstitute human gametogenesis in vi...
https://journals.biologists.com/dev/article/152/17/dev204968/369135/Emerging-principles-and-models-of-human-primordial
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reposted by
Alexandra Dallaire
Maite Saura
4 months ago
New preprint! 🐛 Root-knot nematodes hijack root cells, turning them into feeding sites and making plants very sick. Using a cross-species scRNA-seq approach we mapped this process and show how this knowledge can be used to engineer resistant crops.🌱 A summary🧵 :
www.biorxiv.org/content/10.1...
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I’m super happy to present the first discoveries of the RIKEN-Cambridge Joint Crop Symbiosis Research Team, based in Japan 🇯🇵
doi.org/10.1101/2025...
A thread 👇
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Reductive evolution of the DNA replication machinery in endosymbiotic fungi
The molecular machinery for replicating and repairing DNA accurately is critically important for life and highly conserved across the Tree of Life. Here we show that two major lineages of fungi, Glome...
https://doi.org/10.1101/2025.09.02.673565
4 months ago
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Alexandra Dallaire
ICOM2026
4 months ago
The call for
#ICOM2026
Symposia applications is now open until October 15. Please see:
icom2026.org/symposia/
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ICOM2026 – Call for Symposia
Call for Symposia The Call for Symposia at ICOM2026 is open! Download Application Form below Deadline for submission: 15 October 2025 Decision: 1 November 2025 ICOM2026 will host a series of sympos…
https://icom2026.org/symposia/
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Alexandra Dallaire
Society for Molecular Biology and Evolution
5 months ago
We are excited to announce the SMBE Fellows Program! ✍️ Designed to provide networking and mentorship opportunities to early-career researchers through scientific writing in evolutionary biology for
@molbioevol.bsky.social
and
@genomebiolevol.bsky.social
📆 Aug. 31 🔗
smbe.org/smbe-fellows-program
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Alexandra Dallaire
Matthias C. Rillig
5 months ago
Very happy to share this paper, out in Nature, written with Henning, whom I met during my sabbatical at
@oistedu.bsky.social
From bench to big boss: mitigating the widening gap between PI and lab An important topic....would be curious to hear your thoughts...
www.nature.com/articles/d41...
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From bench to big boss: mitigating the widening gap between PI and lab
Laboratory dynamics can change as the age and experience of the principal investigator increase. But there are ways to combat this.
https://www.nature.com/articles/d41586-025-01912-4
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Guess the ggplot colour palette!
5 months ago
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Alexandra Dallaire
IFBC_2025
6 months ago
🚨 Final days to register! ⌛️ Don’t wait until the last minute ⏰ —secure your spot and get ready to connect with scientists from around the world in stunning Crete! 🌍🧫 Let’s advance fungal biology together! 🔗
ifbc2025.maich.gr
📣 REGISTER NOW! 🔁 Share to reach the whole myco-community!
#IFBC25
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Alexandra Dallaire
Héctor Montero
6 months ago
Great article. The evolution of symbiotic nitrogen fixation is fascinating and complicated 🎢
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One versus many independent assemblies of symbiotic nitrogen fixation in flowering plants - Nature Communications
Symbiosis of nitrogen-fixing bacteria in evolutionarily novel “nodules” of diverse flowering plants including legume crops was assembled from pre-existing functions. Testing hypotheses of single vs. m...
https://doi.org/10.1038/s41467-025-60433-w
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So happy I had a chance to contribute to this review! Nice summary and thoughts on past, present and future attempts to transform
#arbuscular
#mycorrhizal
#fungi
🍄🧬
add a skeleton here at some point
6 months ago
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Alexandra Dallaire
Inside Higher Ed
6 months ago
Opinion | Beyond ‘Grit’ and ‘Growth Mindsets’ Focusing on internal traits distracts us from the work of encouraging behaviors that support student success, Jarek Janio writes.
#HigherEd
#EDUSky
#AcademicSky
bit.ly/442Suug
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Beyond “Grit” and “Growth Mindsets” (opinion)
Focusing on internal traits distracts us from the work of encouraging behaviors that support student success, Jarek Janio writes.
https://bit.ly/442Suug
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Alexandra Dallaire
Ryohei Thomas Nakano (Hokudai)
7 months ago
Hey my fellow Germans! I wasn't aware, but there is an AvH-JSPP postdoc fellowship, dedicated to German citizens aiming to do their postdoc in Japan. It covers salary + travel to Japan + startup for your life in Japan. Let me know if you are interested!
www.humboldt-foundation.de/en/apply/spo...
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JSPS Research Fellowship
The Japan Society for the Promotion of Science (JSPS) Research Fellowship supports you as a highly qualified postdoc from Germany in conducting your research in Japan – regardless of discipline.
https://www.humboldt-foundation.de/en/apply/sponsorship-programmes/japan-society-for-the-promotion-of-science-jsps-research-fellowship
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Alexandra Dallaire
Elise A. Lucotte
7 months ago
Our new paper is out! We observed a loss of function in mating compatibility for HD genes for the first time in basidiomycete fungi, and new evolutionary strata in the absence of sexually antagonistic selection!
@tatianagiraud.bsky.social
More details here 👉
www.nature.com/articles/s41...
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Repeated loss of function at HD mating-type genes and of recombination in anther-smut fungi - Nature Communications
Basidiomycete fungi typically have two mating-type loci located on different chromosomes. Here, Lucotte et al. report the convergent loss-of-function of mating-type genes across several species of phy...
https://www.nature.com/articles/s41467-025-60222-5
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Nice concept! Single-Allele Chromatin Tracing Reveals Genomic Clustering of Paralogous Transcription Factors as a Mechanism for Developmental Robustness in T Cells
www.biorxiv.org/content/10.1...
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https://www.biorxiv.org/content/10.1101/2025.05.30.656885v1
7 months ago
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Clade-wide fungal proteome analysis reveals structure-function conservation in divergent Dicer proteins 🍄
www.biorxiv.org/content/10.1...
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Clade-wide fungal proteome analysis reveals structure-function conservation in divergent Dicer proteins
Dicers (Dcrs) are central proteins involved in the biogenesis of small RNAs (sRNAs) in eukaryotes. Most of the knowledge on Dcr structure, function and evolution comes from studies conducted in animal...
https://www.biorxiv.org/content/10.1101/2025.04.28.651110v2
7 months ago
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Alexandra Dallaire
Kenichi Tsuda
8 months ago
This is wild. Chromosome distributions into different nuclei! Distribution of haploid chromosomes into separate nuclei in two pathogenic fungi
www.science.org/doi/10.1126/...
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Distribution of haploid chromosomes into separate nuclei in two pathogenic fungi
Nuclei define eukaryotes, enabling macromolecular compartmentalization and cellular regulation. Each nucleus is believed to contain one or more haploid sets of chromosomes (1N). However, we discovered...
https://www.science.org/doi/10.1126/science.abn7811
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Alexandra Dallaire
Justine Karst 🇨🇦
8 months ago
'Genome sequences provide evidence for ancient fungal assault on the ancestors of land plants' -->Does this mean that mycorrhizas evolved from an antagonistic relationship between plants and fungi? Is this a correct interpretation?
www.annualreviews.org/content/jour...
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Early Diverging Fungi: Diversity and Impact at the Dawn of Terrestrial Life | Annual Reviews
As decomposers or plant pathogens, fungi deploy invasive growth and powerful carbohydrate active enzymes to reduce multicellular plant tissues to humus and simple sugars. Fungi are perhaps also the mo...
https://www.annualreviews.org/content/journals/10.1146/annurev-micro-030117-020324
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Weehee! 🎈
add a skeleton here at some point
8 months ago
0
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Alexandra Dallaire
IFBC_2025
8 months ago
PhD student from a low or middle-income country? 🌎 You may qualify for a Registration Fee Waiver to attend IFBC 2025 in Chania, Greece! 🇬🇷🏛️ ➡️All the info:
ifbc2025.maich.gr/registration...
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Alexandra Dallaire
Andrew Alverson
9 months ago
Sigh.
academic.oup.com/ismej/articl...
add a skeleton here at some point
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Alexandra Dallaire
Ahilya Sawh
9 months ago
🍁🚨 WE'RE HIRING!🚨🍁 Our baby lab at the University of Toronto is expanding, many many thanks to funding from
#CIHR
and
@hfspo.bsky.social
. We are in search of a technician, postdoc, and PhD students! Further details on our website (
sawhlab.netlify.app/people/
), please share!
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Alexandra Dallaire
Molly Schumer
9 months ago
With
@hybridzones.bsky.social
&
@jenncoughlan.bsky.social
, we have been working on an update to Daven Presgraves' influential 2010 review on hybrid incompatibilities (
shorturl.at/cJndf
). The preprint is available here (
shorturl.at/DTC48
) with an updated table of almost 100 incompatibilities!
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The molecular evolutionary basis of species formation - Nature Reviews Genetics
Recently, several new speciation genes have been identified that have contributed to our understanding of the molecular details of the evolution of hybrid dysfunction. This Progress article describes ...
https://shorturl.at/cJndf
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Alexandra Dallaire
Andrej Spiridonov
9 months ago
Common cause vs sampling intensity variation in the earliest eukaryote diversity dynamics in the Proterozoic Eon: "...we favor the explanation that the pattern of early eukaryote diversity is driven by variations in paleontological sampling."
doi.org/10.1017/pab....
🧪
#Paleobio
⚒️
#Geology
#EvoBio
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Alexandra Dallaire
Francis Sedgemore
9 months ago
Canada joins Horizon Europe programme
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Canada joins Horizon Europe programme
Canada is joining the growing group of non-EU countries who have associated to the EU's research and innovation programme, Horizon Europe, and will work jointly on large-scale projects tackling our bi...
https://luxembourg.representation.ec.europa.eu/actualites-et-evenements/actualites/canada-joins-horizon-europe-programme-2024-07-03_en
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Bruno Ngou
9 months ago
First post on Bluesky!! ☀️ Very happy to share that my main postdoc work ‘Systematic Discovery and Design of Synthetic Immune Receptors in Plants’ is finally out on Biorxiv!
www.biorxiv.org/content/10.1...
The full story is summarized here:
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Systematic Discovery and Design of Synthetic Immune Receptors in Plants
Plants deploy a diverse array of pattern recognition receptors (PRRs) that perceive microbe-associated molecular patterns (MAMPs) to activate immune responses. Leucine-rich repeat receptor-like kinase...
https://www.biorxiv.org/content/10.1101/2025.03.17.642524v1
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Alexandra Dallaire
Gitta Coaker
11 months ago
www.cell.com/current-biol...
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Evolution of a vascular plant pathogen is associated with the loss of CRISPR-Cas and an increase in genome plasticity and virulence genes
Paauw et al. report on the evolution of a plant pathogenic Xanthomonas pathovar and show that the gain of mobile genetic elements and virulence factors coincided with the loss of the CRISPR-Cas genome...
https://www.cell.com/current-biology/fulltext/S0960-9822(25)00003-X
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