Dvě vědkyně z @mbuavcr.bsky.social - Natalia Slonská a Lucie Najmanová, se zúčastnily soutěže Věda fotogenická, kterou pořádá @akademievedcr.bsky.social. Do soutěže přihlásily snímky, které propojují krásu květu fuchsie se světem půdních bakterií Streptomyces coelicolor.

New week, new tool: Find our Protein Domain Designer tool to generate publication-ready protein domain diagrams here: domaindesigner.farnunglab.com

Structural insights into YheS-mediated release of SecM-arrested ribosome. www.biorxiv.org/content/10.1... 🦠 #ribosome #rnasky

Here, we show that bacterial ribosomes—often viewed as conserved drug targets—actually vary across species due to extensive sequence variation in their drug-binding residues. In some cases, this divergence may lead to intrinsic drug resistance in certain bacterial clades: doi.org/10.1016/j.ce...

Happy to share a new paper from our lab with my little contribution! 🥳🥳🥳 We show that antibiotic resistance ABC-F proteins fine-tune responses to ribosome-binding antibiotics. Thanks to ABC-Fs, bacteria can differentiate between antibiotic classes and even concentrations for a tailored response. 🦠💊⬇️

New ABCF article from @balikovalab.bsky.social group! Even though ABCF proteins have the same shape and act on the ribosome E-site, they have very different role in bacteria physiology level. What an interesting topic!🤩 doi.org/10.1128/mbio...

#rnasky #microsky

''natural human tRNAAla variants generate mistranslation leading to defects in protein production that depend on the nature of the amino acid replacement.'' #rnasky Natural human tRNAAla anticodon variants mistranslate the genetic code m.rnajournal.cshlp.org/content/earl...

Preprint from our collaboration with the labs of Gerry Wright and Shura Mankin identifying the first translation inhibitor binding to the E-site of the bacterial ribosome… www.researchsquare.com/article/rs-6...

Insights on how ribosomal RNA modification distant from drug binding site can still affect drug binding, in mycobacterium 🦠 #rnasky #ribosome #microsky

Bye Bye "Ribosome2025", Pacific Grove, California!🌁🌊 It was a very nice conference with beautiful science and amazing people!!🤩👌

Paper alert: www.sciencedirect.com/science/arti...? Proud that we brought together researchers, clinicians and patient/carers to convey our point that it is important to bring novel treatments for bacterial pathogens to patients *also* if they are not on the WHO Bacterial Priority Pathogen list.

Happy to attend this new "Ribosome Conference" in California, Pacific Grove. Beautiful venue and amazing science !! #Ribo2025 #ribosome

Mechanism of release factor–mediated peptidyl-tRNA hydrolysis on the ribosome www.science.org/doi/10.1126/...

Marie Curie fellowship, post-doc hosting oppotunity in my lab. MSCA Post-doctoral Fellowship at IBPC Paris on RNA modifications in bacteria (FRANCE) 🦠💫 euraxess.ec.europa.eu/jobs/hosting...

Does your research revolve around protein synthesis? 👨‍🔬 Then submit your abstract by 1 June for a chance to be one of over 50 selected short talk speakers and share your findings at #EMBLProtein! 💻 https://s.embl.org/trc24-01-bl#EMBLProtein #proteinsynthesis #molecularbiology #translationbiology #mrna

Ok what? #RNASky #RNABiology 🧪

Bonjour, un poste d´IE (biochimie/BM) en mobilité interne (NOEMI) est disponible au Laboratoire de Biologie Structurale de la Cellule (bioc.ip-paris.fr), École polytechnique, Palaiseau. Rejoignez-nous!!! emploi.cnrs.fr/Offres/MOBIN... Merci de faire circuler l´information!

Small RNA pairing in coding sequences can locally slow translation elongation from Storz lab www.cell.com/molecular-ce... #microsky #rnasky

Huge thanks, I feel very honored, and congratulations to the other winners! Publication will hopefully follow soon, stay tuned! 🤘 Presented work done with @balikovalab.bsky.social & @innislab.bsky.social

Congratulation to authors of best student posters Veronika Klapšťová, Jakub Hrubý and Martin Sitte and best student talks Klára Kohoutová and Michaela Novotná @michaelanovotna.bsky.social

The latest discovery from the lab and great colleagues at McMaster and U Illinois, Chicago. Lariocidin, a new lasso peptide antibiotic that inhibits the ribosome. rdcu.be/efdha

🚨The triennial Ribosome Conference will be held June 22-June 27, 2025 in Pacific Grove, California. Registration is open - hope to see many #Ribosome #RNA aficionados there. #RNASky #AcademicSky 🧪 rna.ucsc.edu/rnacenter/ri...

Please spread the word! We have an opening in the Atkinson lab for a post-doc with a focus on the molecular mechanisms of microbial immune systems. Can be a fully computational or experimental or hybrid project. Read more and apply here: lu.varbi.com/en/what:job/... #phage #bioinformatics

Message to my 11 followers in Bluesky: We are pleased to announce that registrations for the International EMBO workshop Ribosome Synthesis: from Mechanisms to Therapy 13th Edition are now open! Details and registration: www.eventsforce.net/hg3/frontend... The Organizing Committee

Our study on translation initiation inhibitors now published after peer review at nature.com/articles/s4146…. Great collaboration with Pohl Milon and team. Data collected at @cssbhamburg.bsky.social

Please repost: Postdoc position in antibiotic discovery in a large multidisciplinary project combining high-throughput approaches, microscopy, AI, and hit-to-lead optimization at @umontreal.ca and @mila-quebec.bsky.social. Apply to [email protected]. See lnkd.in/dVVk4N3s. #microsky

Discussion from @dereklowe.bsky.social of the recent paper in Nature Chemistry from Liu, Polikanov, Myers et al. www.nature.com/articles/s41...

#tRNA #Ribosome #Asite #StopCodon #Readthrough #Scerevisiae www.nature.com/articles/s41...

We are down to 2.32A and 2.61A for these specific ribosome complexes using tandem purification using RAPPL and tagged protein enrichment. In this case it was and hour and 45 minutes prep and 20-50 ml bacterial culture. www.biorxiv.org/content/10.1...

Archaeal protein mediating 30S ribosomal subunit dimerization academic.oup.com/nar/article/...

Latest work of our lab published in Nature Chemistry

News on ribosome hibernation 🦠 #rnasky #microsky Ribosome-inactivation by a class of widely distributed C-tail anchored membrane proteins: Structure www.cell.com/structure/fu...

#cryoET of Mycoplasma pneumoniae Chloramphenicol-bound ribosomes at a global 3.0 Å resolution www.nature.com/articles/s41...

Do you want to work at the interface of molecular simulations, structural biology experiments and #AI? Come to Paris for a PhD at @pasteur.fr 1 PhD position is available in our lab funded by ERC_Research. Please repost!! #compchem #compbio Info 👇 research.pasteur.fr/b/15Hr

EfpL (YeiP) -one of the many rescue factors that relieves ribosome stalling at polyproline seq. 🧪 #Ribosome www.nature.com/articles/s41...

Happy to share the website of RiboMod2025, the "Conference on Ribosomal RNA modifications and snoRNAs" in Bologna June 12-13, 2025 is up at events.unibo.it/ribomod2025 Stay tune for more infos! #RNA #Ribosome #snoRNA #Eiptranscriptomics

Yeast ribosomes adapt to glucose starvation by tethering to mitochondria in hibernation. Prolonged depletion halts protein synthesis and remodels ribosomes to create protective ribosome arrays. #ribosomes #RNASky #RNABiology #translation rdcu.be/d1xqj