I was on NPR last week talking about a new publication that is really important to me - part of our larger effort to change the way we think and talk about both mental and physical health, and how they relate to each other, after stress and trauma. www.knkx.org/2026-01-28/u...

#IDSky First person with H5N5 has died :(

10/ After 14 years of working on this topic, I tell you this with confidence: Highly invasive mercenary spyware is a power abuse machine. It's incompatible with Americans constitutional rights and freedoms. And our legal system and civil society is not prepared for the next chapter.

1. The DOJ has sent threatening letters to several medical journals, focused around whether these journals are spreading misinformation that harms the American people and suppressing alternative viewpoints. I study how the norms and institutions of science facilitate discovery and self-correction.

We opted to join Bainbridge Island’s rally, which had well over 1K+ protestors. One of the speakers we heard was a Japanese American internee who, in 1942, was removed from Bainbridge Island to an internment camp with her family. Her closing words: “Never again is now.”

Defensive gun use is rare but gun violence exposure is far too common. Check out this interview re: our new study in @jama.com Open from @mikeanestis.bsky.social. Watch the full interview for important thoughts on very real threats to our work @ the GVRC. www.njspotlightnews.org/video/rutger...

I’m am adaptation scientist and here’s what I had to say about this—many years ago already.

Mandatory high school civics class that isn’t just like “how a bill becomes law” or whatever but also “how NOAA powers your phone’s weather app” and “NIH helped make your asthma inhaler”

Trump is LYING about Social Security right now. Elon Musk called Social Security a "Ponzi scheme." They are cutting staff drastically at Social Security to make it harder for seniors to get their benefits. These corrupt billionaires need to keep their HANDS OFF Social Security!

On climate, did you know that only 11% of people in the US (and even smaller percentages in Canada, the UK, Australia and beyond) are dismissive? Yet because their voices are so loud and persistent, people often think they’re 50%. This is why I advocate so strongly for using YOUR voice!

Researchers found 15 people in Kansas City who had changed their mind about climate change, and asked them why. Fascinating! link.springer.com/article/10.1...

Mechanosensation of the heart and gut elicits hypometabolism and vigilance in mice | Nature Metabolism www.nature.com/articles/s42...

Exciting new data on psilocybin effects on hypothalamic CRH neurons @gergelyturi.bsky.social Tamas Füzesi & @stressynomics.bsky.social www.biorxiv.org/content/10.1...

Dirty air, dementia, and other adverse brain effects www.nature.com/articles/d41... new Feature @nature.com open-access

New study out now in SS&M from our team @njgvrc.bsky.social! Both frequency + recency of gun violence exposure influence mental health and suicide. More national evidence of the extensive toll that gun violence takes on our collective health and well-being. www.sciencedirect.com/science/arti...

My new year's resolution was to work through the pile of almost-finished papers so... #PrePrintAlert #NeuroSkyence. This is an update to one we put out late 2021, which got delayed with Lilya (lead author) going on maternity leave (yay, lab baby! 🥰). A brief 🧵 1/ www.biorxiv.org/content/10.1...

We've uncovered sex-specific effects of early-life stress (ELS) exposure on fear memory, HPA-axis regulation, and brain metabolism🧠. Unsupervised clustering shows that fear responses are more than only freezing. @mathiasvschmidt.bsky.social nature.com/articles/s42... Highlights in thread👇

All surface temperature products for 2024 are now live. All show 2024 is the warmest year (very clearly). The estimates of the change since the pre-industrial (1850-1900) are more uncertain but range from 1.46 to 1.62ºC. It is therefore *likely* this was the first year that exceeded 1.5ºC.

The Conversation asked me to share my thoughts on the new U.S. Surgeon General Advisory around alcohol and cancer & to break down some of the science in an accessible way. Check it out here: theconversation.com/even-1-drink...

Out in @cellcellpress.bsky.social ! We show that oscillations in norepinephrine and cerebral blood volume are the missing pieces that link NREM sleep to clearance of waste from the brain 🧠💤 www.cell.com/cell/fulltex...

I define hope as the belief that our actions can make a difference. For me, it's not an emotion but rather a daily practice. Every week I share good news of climate solutions, not-so-good news on how climate change is affecting our lives, and something concrete we can do about it. Subscribe here:

Norepinephrine-mediated slow vasomotion drives glymphatic clearance during sleep @cellcellpress.bsky.social @nataliehauglund.bsky.social www.cell.com/cell/fulltex...

Climate change is creating warmer, drier conditions that cause fire seasons in some regions like western North America to last longer and be more active. Read more:

Occasional reminder that there’s no, “it’s too late, its over” for anthropogenic climate change. Every molecule of CO2 that doesn’t go into the atmosphere makes a difference. Preventing 0.1 degree of warming makes a difference. Every bit of climate resilience we build together makes a difference.

To everyone's surprise, it turns out that attaching a money-sucking machine to a hospital system makes it worse.

Light can influence metabolism independent of the circadian clock, according to a new #ScienceAdvances study in mice. Learn more: scim.ag/3DIu7bP

Just published: FDA puts out new guidelines, include testing on more subjects with all ranges of skin colors, to improve the accuracy of pulse oximeters in people with darker skin. Said one source: FDA is now really clearly addressing the issue of racial bias. www.statnews.com/2025/01/06/p...

The idea that we need to shift from assuming pharmacotherapies have effects that are separable from the context in which they're taken is one I agree with. In fact, the significant majority of the medications I prescribe there is evidence to suggest important drug-context interactions.

I encourage everyone to read through Compass' latest description of their "psychological support" model. If this is not in fact psychotherapy, then nothing is. Ironically, this is most evident whenever the authors apparently aim to differentiate their model from (their idea of) psychotherapy, e.g.:

🚨 Breaking #Physiology news: Spinal arteries dilate in response to #noradrenaline! Our new study (www.thespinejournalonline.com/article/S152... ) shows increased spinal cord blood flow in-vivo via β-adrenergic receptor–mediated vasodilation, as spinal arteries lack α1-adrenergic receptors.

"A study of federally funded research projects in the United States estimated that principal investigators spend on average about 45% of their time on administrative activities related to applying for and managing projects rather than conducting active research" www.pnas.org/doi/10.1073/...

Sex or survival—what’s more important? Excited to share our @Nature paper on how flies resolve this conflict. We found a dopamine-based filter that reduces threat perception, helping flies focus on courtship when close to mating. www.nature.com/articles/s41...

“Women are asked more questions during a seminar and the questions asked of women presenters are more likely to be patronizing or hostile. These effects are not due to women presenting in different fields, different seminar series, or different topics…” www.nber.org/papers/w28494

Local Seattle folks - a way you can hold close the memory of a teen who died trying to protect a classmate, support his family, and care for our community.

A key takeaway was that each of 3 cities who implemented public dashboards with data on gun violence (& more!) had unique characteristics (eg, size of city, proportion of vacant homes, concentration of violence) but all of them benefitted from the data. 📊 Data is a powerful tool for change!

Exactly this. Devastating, infuriating, and preventable. Re-upping (yet again) this piece that @proflou.bsky.social, Charlie Branas, and I wrote in the wake of the Uvalde mass shooting. We have many solutions that we know work - it's far past time to implement them: www.latimes.com/opinion/stor...

I am thrilled to serve with my friend Millie on the @acnporg.bsky.social council! If you are an associate member & have ideas or questions about ACNP that you want to share, please contact me. I may not have answers (likely) but it would be great to get a sense of what is on folks’ minds.

Dr. Avishek Adhikari just ended his (very nice) talk with a Negative Acknowledgments slide: "People who refused to give us money". Fantastic. #ACNP2024

Now thinking about applying a strengths based approach with clients with psychotic experiences and digging into the relevant literature… …Thank you to #ACNP2024 for a thoughtful and stimulating Diversity and Inclusion Committee luncheon! Such an important lens shift.

If you’re still around #ACNP2024, stop by poster 82 to chat about the roles of the salience and default mode networks in antidepressant placebo response! Or stop by to chat about rock climbing or family vacations or whatever else you feel like on the final day of the conference. 😃

If you are still at #ACNP2024 and are interested in the locus coeruleus and/or the amygdala, please stop by my poster from the @mbruchas lab examining how both nodes of this circuit mediate stress-induced anxiety-like behavior tonight (W169)!

Love this!

Overheard at #ACNP2024: Person A: "Why do you think we got stuck presenting our posters on the last day?" Person B: "Well, my poster isn't great. Yours isn't that interesting either." For the record - that's not how the order is decided 😬

If you’re still hanging around at #ACNP2024 tonight and you’re interested in the insular cortex, interoception, food intake or single-cell seq, stop by my poster (170)!

Good morning #ACNP2024! Had enough neuroscience yet? Time to learn a little cardiology (as performed by neuroscientist. @Devineffinger.Bsky.social). Specifically, does chronic microdosing of LSD pose a cardiovascular risk by chronically activating 5HT2B receptors? Find out at poster W234 today!!

Immunologists, time to embrace your inner neuroscientist 🧠🧪 Macrophages (yes, #macrophages) release glutamate (yes, #glutamate) to sensory neurons engaging in the muscle stretch reflex. Very cool paper! #neuroscience #immunology www.nature.com/articles/s41...

Delighted to share an update to our preprint, reviewed at @elife.bsky.social, and now sent back for re-review. Colossal work by the team and driven home by @mathiasgua.bsky.social Quick 🧵 of what's new - www.biorxiv.org/content/10.1...

Negar Fani brandishing humor and truth at the women’s luncheon #ACNP2024

Using mass spec @cate-cholamine.bsky.social finds early life stress alters H3K4 methylation which corresponds with changes in open chromatin. Experimental upregulation of an enzyme targeting this change increases susceptibility to adult stress #ACNP20204 doi.org/10.1101/2024...