Natalie hauglund
@nataliehauglund.bsky.social
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Curious about sleep 💤
reposted by
Natalie hauglund
Leon Smyth
7 months ago
Our News and Views on
@nataliehauglund.bsky.social
and Maiken Nedergaard's recent study showing how sleep drives brain waste clearance
@cp-trendsimmuno.bsky.social
www.cell.com/trends/immun...
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Rest and rinse: sleeping rhythms drive brain detox
Sleep is a major driver of waste clearance from the brain, but the mechanisms underpinning brain cleansing during sleep, which are also important for immunological functions, are poorly understood. Re...
https://www.cell.com/trends/immunology/fulltext/S1471-4906(25)00034-1
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reposted by
Natalie hauglund
Yuki Mori
7 months ago
Fantastic 'Banana' Voyage! 🚀🍌 I'm practicing
@napari.fosstodon.org.ap.brid.gy
for my 'real' future scientific presentation. It's truly a fruitful software, and I'm excited to explore more of what I can do with it! :)
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New preprint now online!
www.biorxiv.org/content/10.1...
We created an algorithm to detect NREM sleep micro-arousals and used it to re-analyze LFP data from the motor cortex of sleeping mice 💤 This is what we found:
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https://www.biorxiv.org/content/10.1101/2025.01.29.635246v1.full.pdf
8 months ago
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reposted by
Natalie hauglund
Giulio Bernardi
8 months ago
New preprint from our lab, in collaboration with Jeff Duyn's group at NIH!! 🚨Bergamo et al., "Thalamic involvement defines distinct slow-wave subtypes in NREM sleep." Link:
www.biorxiv.org/content/10.1...
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Thalamic involvement defines distinct slow-wave subtypes in NREM sleep
Slow waves (0.5-4 Hz) are a key feature of non-rapid-eye-movement (NREM) sleep, traditionally believed to arise from neocortical circuits. However, growing evidence suggests that subcortical structure...
https://www.biorxiv.org/content/10.1101/2025.01.16.633402v1
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Great write about our study in
@nature.com
🧠
add a skeleton here at some point
8 months ago
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Out in
@cellcellpress.bsky.social
! We show that oscillations in norepinephrine and cerebral blood volume are the missing pieces that link NREM sleep to clearance of waste from the brain 🧠💤
www.cell.com/cell/fulltex...
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Norepinephrine-mediated slow vasomotion drives glymphatic clearance during sleep
Norepinephrine oscillations during NREM sleep drive synchronized changes in cerebral blood volume and cerebrospinal fluid, promoting glymphatic clearance. Optogenetic and pharmacological manipulations confirm that vasomotion, regulated by norepinephrine, acts as a pump for brain fluid transport.
https://www.cell.com/cell/fulltext/S0092-8674(24)01343-6
9 months ago
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