My theory that AI maximalists don’t know how to use a computer remains undefeated so far

forgive me, for I have Hobbesposted

I listened to and largely appreciated this conversation. One notable moment was when Roberts talked about how everyone falls victim to bias, and he and Hobbes agreed that it's largely a collective responsibility to call out and dig into these situations. Which is true! But...

I just remembered that Square renamed itself to Block a while back. An all-time rebranding blunder, right next to Meta.

I’m so tired of fighting for my life against this long list of lies 😩

there's a reason why collaborations are forming between longevity, regenerative medicine, and infection-associated chronic condition researchers.

The CDC says it's fine to resume normal activities 24 hrs after Covid symptoms are improving. A new, large prospective study with digital tracking shows recovery takes much longer than that www.thelancet.com/journals/lan...

always a good sign when you jolt awake saturday morning with a headache and a pile of stress

This weird world we live where people want to live in pretend times where a novel corona viruses isn’t still absolutely destroying people (just not in active hospitalizations in the same numbers as before), but then people have to unpretend when their health is part of their job.

Generational political talent. Epochal even.

nightmare scenario

There will never be fewer reasons to get off Substack.

The transcript of the MN hearing where an AUSA said “This job sucks” is remarkable for more reasons than that. It’s a searing portrait of a crisis perpetrated by depraved & oblivious high-level officials. Read it all. ... 1/7 www.documentcloud.org/documents/26...

WHAT'S up me hearties it be thy boy Ahab, with the biggest ounce of gold giveaway ever hath ye seen on the channel. Swerve not thy fixed purpose to attend this one, guys! But first I must tell ye the tale of SQUARESPACE, who be thy sponsor today

"We know enough." Watch this.

I just thought everyone should see this

For people with tech background concerned about the Clipper 2 upgrade/migration, check out the Cubic slides being presented today at Clipper Executive Board. Many of the problems are failures of basic scaling and QA missing predictable corner cases. mtc.legistar.com/LegislationD...

I asked Kevin about VNS use in POTS, Long Covid, what may be considered an ideal use case This is part of his reponse. Then there's the ear access.....

This is finally out. Very short take home. All the variation in spike that produced the immune escape characteristics of Omicron can occur in one single persistently infected individual over the period of a year. This is why persistent infections matter www.cell.com/cell-reports...

DOCTOR: I told him he needed to get out to a show, that was how he would cure his depression. CHOTINER: So you learned this technique in school? DR: No, not— listen it was good advice. Pagliacci was in town. C: Right. Is it standard to give advice before learning a patient’s name? DR: Now look

uh

we absolutely need to know who he sent this to. how is this something the public is being kept in the dark on???

“A growing body of research continues to reveal information about the virus and its ability to cause harm long after initial infections resolve, even in some cases when symptoms were mild. “The discoveries raise fresh concerns about the Trump administration's COVID policies.”

Good time to remember that Bernie Sanders is the most popular politician in America www.gelliottmorris.com/p/who-is-the...

Damn. Tuberculosis cases are occasionally reported in the U.S., but an outbreak of 50 cases in San Francisco is extraordinary. There's no good TB vaccine -- BCG is used in some countries, but it's not very effective. www.sfgate.com/bayarea/arti...

What drives immunosenescence—the degradation of function our immune system with aging that increases the risk of age-related diseases? Today's report: B cells are identified as the bad actors because they induce T cell (CD4) dysfunction and inflammaging science.org/doi/10.1126/...

happy won-my-state-board-of-health-appeal-against-my-health-insurance-company day to me

Our epidemiologists looking at measles trends across the US

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1. The spread of #measles in the US shows no sign of abating. As of 1/29 there have been 588 confirmed cases so far in 2026, #CDC reports. The tally for January is higher than the total year tallies for all but 4 years since 1992. The cases were reported from 17 jurisdictions. Only 3 were imports.

There’s a terrific documentary (premiered at Sundance, shortlisted for an Oscar) that vividly depicts what you’re in for from the medical establishment if you get a disease like Long Covid. MANY people imagine they’ll be able to find a Dr. House to sort them out. Reality…is very far from that.

I wish healthy people understood that if you develop a medical condition that doctors don’t understand, you’re gonna be TREATED BADLY BY DOCTORS. And there’s a widely circulating virus that leaves people with incurable medical conditions that doctors don’t understand.

memo to all my friends who say that their allergists are baffled by new onset allergies

Hey sincere post for a sec, I'm involved in union organizing around AI and my media employer is planning layoffs. If you know people especially in nonprofit newsrooms who have dealt with this kind of thing @ me or DM me

NEW: Liam Conejo Ramos, the 5-year-old who ICE agents in Minneapolis nabbed last week and shipped off to a Texas detention facility with his dad, is now in poor health, his school superintendent told me today www.huffpost.com/entry/liam-c...

“are you scared of a fucking whistle dawg” has been knocking around my head all day

English translation of statement from Ecuadorian Consulate regarding ICE’s attempt to enter their building in Minneapolis today:

really glad to see this piece by @brittashoot.com in @thesicktimes.org about the abrupt closing of Metrodora Institute. I'm still left with more questions than answers but I'm glad that the stakes for patients were so clearly described. thesicktimes.org/2026/01/27/m...

people are in disbelief when i explain to them that as a 90s kid in portland i swished fluoride pills every morning in my elementary school classrooms

jfc

Well now.

This is the coolest fucking form of solidarity I have ever seen. Bravo.

Demand the prosecution of Greg Bovino, Kristi Noem, and everyone in ICE and CBP who committed crimes on their orders.

if bovino is out and conservatives are turning on noem then there is a real opportunity to demand that miller resign too.

Normal thing for a major urban American newspaper to have to post.

Totally normal for the local newspaper of record to publish information on the types of chemical munitions the government is deploying against the people.

terrific new Ben Taub piece — it cracks a long-cold case of infanticide; it's a bombshell for maternal health, child protection & opiate toxicology protocols; it exposes the Lancet’s scandalous indifference to validity of what it publishes — it should make noise www.newyorker.com/magazine/202...

Hey it's me, your favorite Social Media Cryptid! I'm running a flash fundraiser for our local anti-ICE community network in Ventura County. These postcards are going out for $5 a pop. I'm @Lucy-Bellwood on Venmo. DM me with how many you'd like and a good mailing address and we'll make it happen 💛