During the last #WorldCup, I randomly found my long lost Mexico '86 #Panini sticker album. And with England at the Azteca next, I thought you might like to see it. It was the first World Cup I can remember, and I can hardly believe it was 40 years ago. Let's hop into the DeLorean, shall we?... 🧵

Don Quixote, Pedro Almodavar, Julio Iglesias, Francisco Goya, can you hear me? Your boys just took one hell of a drawing.

Yorkshire, indeed the world, has lost some of its colour today. Garrowby Hill, a Yorkshire landscape by David Hockney, 1998. So long, David.

OCEANIA HAS ALWAYS BEEN VERY CLOSE TO A DEAL WITH EURASIA

Everything you can expect from the World Cup Opening Ceremony. Music from #Uppbeat (free for Creators!): uppbeat.io/t/benjamin-b... License code: JVYDUZB9GVWKNVC5

Delighted that this is now out in its final form! 🥳 It's a fun story about an EF hand that doesn't bind Ca2+, but instead works as a ubiquitin-binding domain. Huge thanks to the rest of YK lab, the @mrcppu.bsky.social, and our collaborators (@sebastianglatt.bsky.social)!

"Let's say this Twinkie represents the outright racists in the UK when that BNP list got leaked in 2008. According to this morning's sample, it'll be a Twinkie....35 feet long and weighing approximately 600 lbs"

A fellow of the Royal Society slashed funding for disease prevention, leading directly to the deaths of uncounted children. He promotes white supremacy and is actively encouraging racist violence in the UK. But he's Elon Musk, a billionaire. So the Royal Society does nothing. @royalsociety.org

Violence on the streets of the U.K. incited and enabled by Elon Musk, a fellow of the @royalsociety.org. When will our national academy stand up for the values it claims to espouse?

I have to say, listening to the Today programme dedicate an entire (context free) section about whether migrants are more likely to be convicted criminals *the morning after* hundreds of non-migrants of my own ethnicity committed a pogrom is blood boiling.

Just need everyone to know that the Belgium men's soccer team has new jerseys based on the art of Rene Magritte and this is the official photo shoot

This just gets worse, and worse, and worse.

'Loot from the Rainbow' Arthur Ferrier, Tattler Magazine, 1928 Scottish artist, illustrator & cartoonist #Pride2026

Mammalian gene naming conventions and the potential for this kind of mistaken identity have long been a pet hate of mine. There will definitely be other examples of this out there.

Amazing lab, doing fantastic work. Highly recommend. And it's in Dundee, which is obviously a bonus. 😜

1/ Sharing my article in TIBS: "Science is always unfinished: rethinking the demand for complete stories." The cost of that demand: delayed dissemination, cherry-picked data, and an endless "one more experiment" loop. authors.elsevier.com/a/1n0XU3S6Gf...

The known protein universe just got a lot bigger. A newly released artificial-intelligence tool has generated an atlas of more than one billion predicted protein structures and billions more protein sequences. #AI #biotech

The arc of history is long, but it bends towards the Vatican including a LinkedIn clip art of a woman in a hijab under "The true human being"

@johanduchene.bsky.social @sholtodavid.bsky.social Spent the last hour looking, found ten more apparently manipulated Western blots in Thermo Fisher's antibody verification data (across eight different catalogued products). Thread below. www.thermofisher.com/antibody/pro...

By this point we need to make a list of what ubiquitin doesn’t do:

10 days left to register for the 2026 EMBO ubiquitin conference! Join us in coastal Puglia, for a jam packed schedule on all things ubiquitin (and friends). Fantastic line up of speakers and an impressive amount of opportunities for ECRs and networking. meetings.embo.org/event/26-ubi...

You know the most destructive molecule for my experiments is Air? ITC thermogram shifts? Bubble. Gel refuses to run properly? Bubble. Crystallization ruined? Bubble. Mysterious signal artifacts? Also bubble. My troubleshooting career = fighting microscopic air pockets with a pipette tip. #origichals

still not quite over the fact that i watched 15 year olds get sued for millions of dollars for downloading twelve songs and now we all have to accept AI slop because every tech company in the known universe decided that IP laws don't exist now that they're inconvenient for them

Excited to be in Edinburgh for the next few days at the pediEDI 2006 conference on Protein Evolution, Design & Informatics, organised by @biochemsoc.bsky.social. Looking forward to learning lots! #BiochemEvent

We lost Douglas Adams 25 years ago today. This has made a lot of people very sad and has been widely regarded as a bad move.

Our paper is now out in @natcellbio.nature.com! @craigmcrews.bsky.social www.nature.com/articles/s41... We identify a new regulator of the quality control system that protects one of nature's most important molecular machines: the ribosome. QC failure → unmitigated metabolic stress & cell death.

#proteostasis The atypical E3 ligase HOIL-1 safeguards the ribosome during cellular stress www.nature.com/articles/s41...

Join us! TENOVUS funded 3-year PhD studentship available in the De Cesare lab www.dundee.ac.uk/phds/opportu... #ubiquitylation #PhD 🎓

🎯🎯

Interested in non-proteinaceous ubiquitination, induced proximity or glycogen? Then you should have a look at our newest article, “Ubiquitination of glycogen and metabolites in cells and tissues”, just published in Nature: www.nature.com/articles/s41...

We found that TIR domains in animal immune proteins, including the human TLR4, are enzymes that cleave NAD+ to produce the signaling molecule cADPR Read our new preprint by talented Bohdana Hurieva: “Conserved catalytic activity of immune TIR domains in animals” www.biorxiv.org/content/10.6...

🎉Excited to share our new preprint! TIR domains from diverse animals, including human TLR4, are catalytically active and produce cyclic ADP-ribose (cADPR). This enzymatic activity is widespread in animals and conserved across the tree of life. www.biorxiv.org/content/10.6...

The oldest known image of Keith Richards, published around 1140 AD ...

Don't be shy to take on a little two-week side project. These five months will be the most precious three years of your academic journey.

I’m looking for an automated way to read others’s scientific data without giving credit or acknowledgement, and also claim full credit for insights from it. And I want it to have a fitting name OAI: say no more

As day breaks, the extent of the scene is revealed; numerous icebergs of all sizes are scattered across the whole area, and stretching to the northwest is an enormous icefield. The lifeboats themselves could be seen scattered over an area of four or five miles. #Titanic

From then until 4am, the Carpathia altered its course very often to avoid half a dozen icebergs, with many more being passed and some falling astern on either side. #Titanic

Afterwards, Eva Hart and her mother talked about the terrible screams of the people in the water. Esther recalled the terrible silence that followed, saying that it was as if the world was standing still.

Twenty minutes after the Titanic had foundered, most of the people in the water are now either unconscious from exposure or dead. The survivors are left in silence and in the dark, apart from occasional green flashes of the Northern Lights on the horizon and the dying embers of meteors overhead.

To those in the nearby boats, the shrill cry of those in the water begging for help is unforgettable. In later life, Frank Goldsmith Jr. in boat C lived near Navin Field baseball stadium in Detroit and the roar of the crowd reminded him of the desperate yells of the dying.

Over 1500 people, buoyed up by cork lined life jackets, are now struggling in the frigid water for life. With a lifespan of less than 20 minutes and with hypothermia starting to affect most people, the aim is to get out of the cold water before they perish of exposure. #Titanic

Attaining the perpendicular, the severed stern hangs in the air for a little time before plunging down out of sight to the ocean floor 12,500 feet below at 2.20am. In boat 13, the occupants whisper, 'She's gone. That's the last of her.' #Titanic

As the ship disintegrates, the rearmost funnel collapses aft and the lights flicker out leaving everyone in near darkness except for a canopy of dazzling stars, leaving those in the boats to gaze upon the silhouette of the broken vessel. #Titanic

With the stresses on the hull increasing, a buckling sound is heard. Those in the water swim for the two collapsible boats, 'B' having now drifted to starboard. Moments later the forward funnel falls, killing many in the water and producing a wave that pushes 'B' clear.

As water comes trickling over the forward bulkhead on the boat deck and up the access stairs from A deck, the bridge takes a sudden dip underwater, briefly rises out of the swell and then submerges again. #Titanic

As the crew toil, Captain Smith walks by to the bridge with his megaphone in hand and says, 'Well, boys, do your best for the women and children, and look out for yourselves.' Accounts exist that he also exhorted his men to 'Be British' and towards the end, 'Each man for himself.' #Titanic

A little later, Captain Smith comes to the wireless cabin and releases Bride and Phillips from their toil, but the men continue with their work. As Phillips resumes, his power reduced, a stoker comes into the cabin and tries to quietly slip his lifejacket off his back. #Titanic

At 1.57am, the last verified signal from the Titanic is heard by the Carpathia; it is another mention that the engine room was full up to the boilers. Cottam is listening intently but hears nothing further, while the SS Caronia only picks up unreadable signals. #Titanic

Realising that the end is imminent and there are only a few lifeboats left, people on the ship prepare for their own escape by throwing barrels, chairs and anything else that will float overboard. #Titanic

Colonel John Jacob Astor, the richest man on the ship asks if he can accompany his pregnant wife Madeleine but he is refused. With the boat again underoccupied (about 30 out of 65 spaces utilised), the boat is lowered and is found to only have one crewman aboard. #Titanic