“It's supernatural Extraterrestrial I know a bar out in Mars Where they drivin' spaceships instead of cars” #KatyPerry #halloween

@ninaluong.bsky.social is really upping her costume game this year. And she can still work in it!

We lost an icon today! Activist, scientist, and a difficult woman! #JaneGoodall

Our final contribution to this collaboration is now online. We obtained electrophysiological recordings of DRG/TG neurons and Fos+ neurons of spinal dorsal horn & vlPAG in 2 models of neuropathic pain to study the actions of a humanized P2X4R scFv #PainResearch www.sciencedirect.com/science/arti...

⚡We are finally electrocuting DRG neurons in the @alleslab.bsky.social since moving to @cincychildrens.bsky.social! #PainResearch #ephys #NeuroSkyence

🧪Biomarkers in a clinical setting for Alzheimer’s! Scientific work in identifying biomarkers for all sorts of health conditions leads to faster diagnosis, informs treatment, and improves health!

🧪Word of the Week: Biomarker A measurable signal in the body, like a molecule in the blood, that tells us something about health, disease, or response to treatment. For pain, biomarkers could help make the invisible visible, giving us ways to track or predict pain. #SciComm #PainResearch

A blood test for pain? New work in Nature identifies circulating biomarkers that distinguish chronic pain states—offering a path toward objective, biologically grounded diagnostics. #PainResearch #Neuroskyence #Biomarkers #ScienceWatch #SciComm #ScienceInTranslation #ChronicPain

Doing my best to get better at this! You will see more and more from me as I try to communicate what we do, how we do it, and what it all means! Hoping to reach not just the science folks here on BS but non-scientists as well!

1/ Word of the Week: Dorsal Root Ganglia (DRG) Clusters of nerve cell bodies (soma) near the spinal cord that relay sensory signals - including pain - from the body to the brain. Curious what they look like in real human tissue? See thread below #NeuroSkyence #PainResearch #ChronicPain #SciComm

One of our final papers from this collaborative effort involving collaborators at UNM, Mayo Clinic, & McGill. Here we validate a humanized scFv targeting hP2XR. Kudos to first-author @docnessmonster.bsky.social & former lab member Mark S. for making this happen! journals.sagepub.com/doi/10.1177/...

🧠From Lab To Life Why do peripheral nerves suffer axonal loss in diabetes? A study led by @dianatavf.bsky.social from the @tedpricethepainguy.bsky.social lab showed how inflammation leads to neural fibrosis in diabetic peripheral neuropathy! #PainResearch #Neuroskyence #FromLabToLife 1/

📸 Big day in the lab! Our new electrophysiology rig is officially up and running — huge thanks to everyone who helped make this happen. Excited for the science ahead! 🧠⚡️ @alleslab.bsky.social @cincychildrens.bsky.social #PainResearch

This work is finally online as in-press preview! JCI - Cell and molecular profiles in peripheral nerves shift toward inflammatory phenotypes in diabetic peripheral neuropathy www.jci.org/articles/vie...

FlyBase, a Drosophila database, will lose a third of its team in early October because the Harvard grant that covered the employees’ salaries was canceled. Scientists warn that losing FlyBase could devastate fly research. By @claudia-lopez.bsky.social www.thetransmitter.org/community/ha...

🔬 Very cool work from @aubinmoutal.bsky.social, @khannalabuf.bsky.social, and team! These studies reveal how auto-antibodies—like those seen in autoimmune diseases—can directly target sensory neurons in the dorsal root ganglia, driving painful neuropathies. #PainResearch

Gabapentin is widely prescribed for nerve pain, but it doesn’t work the same for everyone. We studied actual human sensory neurons from donors and found that some responded strongly - and others hardly at all. #fromlabtolife #neuroskyence #PainResearch 1/4

🧠 From Lab to Life New research shows Tylenol may quiet pain at its source by blocking Nav1.7 and Nav1.8, sodium channels critical for pain signaling. That’s a big deal for the most common active ingredient in U.S. meds. 1/4 #FromLabToLife #PainResearch #NeuroSkyence

Now online - our studies of mouse and human sensory neurons in the context of visceral pain! #PainResearch journals.sagepub.com/doi/10.1177/...

Our collaborative study with the de la Peña lab is now online! Here we analyzed ephys & transcriptomic actions of gabapentin on hDRG neurons. Kudos to co-first authors Jenna & @docnessmonster.bsky.social. Special thks to our donors & their families #PainResearch journals.sagepub.com/doi/10.1177/...

In case anyone tells you “you aren’t worth anything,” your genetic data is worth $17 million. #23andMe #Regeneron #DNA #IAmNotForSale

Cool history of #LLMs told by the experts! #ai

We are officially in Cincy! #neuroskyence #painresearch

We made it to St. Louis!!! #DogIsMyCopilot #STL #GatewayArch

In Oklahoma City we stayed at the Fordson Hotel. It used to be a Model T Assembly plant! Gorgeous hotel in a nice neighborhood west of downtown! Pierre and I finally felt like we could relax and breathe for the first time in days! #DogIsMyCopilot #Ford #ModelT #OKC #MovingOnUp

Hasta Luego Albuquerque! We are off on a new adventure to Cincinnati #NewBeginnings #CincinnatiBound

Our book chapter is online! #painresearch #neuroskyence

NIH announces that it will move all grant reviews to Center for Scientific Review (CSR) and terminate about half of its review staff. This comes as there is already a building backlog from cancelled review meetings and layoffs. "We're already massively behind schedule," a review officer tells me.

Congrats to Dr. @goinsyeah.bsky.social for defending her thesis today 🎉🥂

BIG NEWS for @standupforscience.bsky.social New Mexico! The Governor of New Mexico officially signed a proclamation declaring Friday March 7th, 2025 as Stand Up For Science Day!! @govmlg.bsky.social I stand for science, New Mexico stands for science. I'd like to know, what do you stand for?

Yes, there is an injunction, but... "In an unprecedented move, the US National Institutes of Health (NIH) has begun mass terminations of research grants that fund active scientific projects because they no longer meet “agency priorities”. www.nature.com/articles/d41...

Got to hang with the amazing @tedpricethepainguy.bsky.social today in NM! Talked some pain research and of course the terrible Luka trade! @goinsyeah.bsky.social

Though the cause of death has not been announced, this sounds like carbon monoxide. As I almost lost my life last year to carbon monoxide poisoning, this is a reminder to have alarms at home and travel with an alarm. This is a tragedy that can be prevented. My thoughts go out to their families 💔

In case anyone needs to understand what’s happening to science in the USA, this episode did a great summary!

I just reached out to my senators about the NIH situation. If you need to find out how much impact NIH has in your state in terms of dollars in and their economic impact here's a link: www.unitedformedicalresearch.org/nih-in-your-...

5,562 proteins were found to have tissue-specific enrichment across 32 human tissues. The majority of them (3,088) are enriched at the protein but not RNA level. The brain hosts the largest number of proteins that are only enriched at the protein level but not RNA level.

Many things to be concerned or upset about right now, but almost eradicating cervical cancer for kids growing up today is a huge win for the future.

Missed this initially, but it's anyways a good time to start the 2025 reading list! 🐭 #PainResearch pmc.ncbi.nlm.nih.gov/articles/PMC...

Totally worth a watch! Reading the book ‘Behave’ right now and this talk really highlighted that we have more control than we think #neuroskyence

New publication alert from our lab! 🚨 Could circadian clock genes like BMAL1 and PER2 hold the key pain chronification? Read our latest review: BMAL1 and PER2: Mechanistic insights into osteoarthritis-associated pa... www.sciencedirect.com/science/arti... #ChronicPain #ClockGenes

I’ve written about my journey with chronic pain and why I’m so passionate about #PainResearch. Instead of letting pain define me, I’ve used it as fuel to drive my research and productivity. Read my story and join me in the mission to advance the understanding and treatment of chronic pain!

Very cool work on ER/PM junctions in neurons and how they regulate VGCCs. #neuroskyence

Check out my analysis of #PainResearch posts and engagement on BlueSky since the #Xodus in November 2024. Hoping as more scientists join the platform we can spark more interesting discussions and foster new collaborations. #neuroskyence

Now that I have more followers I would love to add more artists to this starter pack! I have included several neuroscientists that are artists as well as artists that create neuro inspired art! All mediums are welcome! Podcasts, Visual Art, Authors, etc! Comment to be added and feel free to share!

Is capitalism completely antithetical to the public good or just mostly?

The #neuroscience behind art therapy reveals how creative expression naturally activates healing. It's not about talent – it's about engaging your brain's remarkable capacity for growth and adaptation through art-making. 🎨 🧠 #ArtTherapy #Healing arttherapywithnicole.substack.com/p/the-scienc...

Exciting news! Our latest preprint on neuroimmune mechanisms in a murine chronic back pain model is available. Congratulations to @goinsyeah.bsky.social on your first author publication! A big thanks to @alleslab.bsky.social and the entire team for their hard work! #neuroskyence #painresearch

Looks like all members of the @alleslab.bsky.social will be moving! Most of us to Cincy & one of us for a great postdoc opportunity elsewhere. Excited to see great things from each of you! 💪👩‍🔬🔬 #PainResearch @docnessmonster.bsky.social @goinsyeah.bsky.social @drjones26.bsky.social

New year, new notebooks! I designed these based on some images I took of some sensory neurons. Seemed like an appropriate lab holiday gift! #neuroskyence #PainResearch #SciArt

I am hoping my #neuroskyence network can help my friend! Many of you study ketamine therapy for mental health so you know how effective this treatment can be for PTSD. Anything helps!