Children born to mothers with T1D are less likely to develop T1D than those with an affected father or sibling- linked to changes in DNA methylation at T1D risk genes

The interaction of GLP-1 medicines with the immune system is complex, enabled by direct and indirect actions, including neural inter organ communication. These studies have been led @SinaiHealth by CK Wong. His latest perspective here in the JCI www.jci.org/articles/vie...

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto. www.nature.com/naturecareer... Please repost!

💫NEW: @buszczaklab.bsky.social @jun-wu-lab.bsky.social & co use human #brain #organoids to dissect patient AIRIM variants associated with neurodevelopmental features. A subset of variants impaired #ribosome production and protein synthesis, and delayed radial glial cell specification. bit.ly/4lvVBBP

Amylin and calcitonin differentially affected AMYR subunit assembly and disassembly in a RAMP-specific manner www.science.org/doi/10.1126/...

Here Professor Schertzer and colleagues identify that microbial-derived D-lactate contributes to host glucose and lipid metabolism and can be trapped therapeutically to improve metabolic disease during #obesity www.cell.com/cell-metabol...

Smaller islets are preferentially lost during the development of T1D diabetesjournals.org/diabetes/art...

Happy Canada Day! 🇨🇦 I'm excited to be part of this special topic and thrilled to share our work with the public. Research matters, and we truly appreciate the support from everyone involved, including the government and funding agencies.

Breakthrough T1D Walk 2025 in Saskatoon 🩵💙🩵

Amylin returns to the metabolic stage with a more powerful story to tell #weightloss @natrevendo.nature.com www.nature.com/articles/s41...

The metabolic syndrome and young-onset dementia, from a nationwide cohort of ~2 million people www.neurology.org/doi/abs/10.1...

Check out our recent review describing the bidirectional regulation between the ER and mitochondria www.mdpi.com/3216548

It was a pleasure to co-author this article alongside amazing folks at Carleton. Please check out our EDI resources! Tools for transformation: a teaching toolkit and research pocket guide for advancing equity, diversity, and inclusion in science and engineering www.facetsjournal.com/doi/10.1139/...

More data highlighting insulin mRNA decay and the extent of ER stress in beta cells linked to the pathophysiology of #T1D #genetics @cellcellpress.bsky.social www.cell.com/cell/fulltex...

Excited to share our publication in @cp-iscience.bsky.social Islet single-cell transcriptomic profiling during obesity-induced beta cell expansion in female mice #IMM @uthealthhouston.bsky.social @bcmhouston.bsky.social 🧵 www.cell.com/iscience/ful...

WCVM is hiring a TT assistant/associate professor: wcvm.usask.ca/departments/... (Saskatoon is beautiful- even in the winter☺️)

Up front & free to read in our Jan issue #editorspicks: Targeting the NLRP3 inflammasome–IL-1β pathway in type 2 diabetes and obesity tinyurl.com/bdf9ec33

Saying goodbye to Vancouver 🥺

How to write a grant? 1. The application is for the reviewer, not you, the applicant. 2. Communicate in stories. 3. Make your story cohesive—leave no puzzling gaps. 4. Make your story resonate to keep the reviewer reading. 5. Accept chance and noise in peer-review. www.pnas.org/doi/epub/10....