Way to call out these thieves, perfect line.

My overview of MSI-H colorectal cancer management post ASCO and ESMO, aka “the ATOMIC diss track,” is up on VuMedi: www.vumedi.com/video/manage...

Next week LinkedIn will use your personal data for AI training by automatically enabling permissions. To manually turn off go to: Settings ➡️ Data Privacy ➡️ under “How LinkedIn uses your data” click “Data for Generative AI improvement” ➡️ toggle off

Join us as we take a step back in time and celebrate all we have accomplished in immuno-oncology over the past 40 years! We will be remembering all our IO milestones as we lead up to our 40th Anniversary Annual Meeting! sitcancer.org/2025/home

Extremely useful for spectral flow cytometry enthusiasts- thanks @labliston.bsky.social I will share with our core too

Finally read the paper and it's worth the buzz. mRNA vaccines saved 20 million lives in a global pandemic and the technology is opening up new avenues for the treatment of deadly cancers. This is really one of the most impactful scientific developments of our time. www.nature.com/articles/s41...

YAP is a tough drug target with implications in resistance to immunotherapy and other treatments, these are some very encouraging results www.nature.com/articles/s41...

The tumor immunology and immunotherapy lecture "Know the System Know the Drug,” that Dan Schrum and I recorded for trainees, is up on YouTube! If you are interested in tumor immune evasion and immunotherapeutic mechanisms of action, check out our talk. m.youtube.com/watch?v=atiS...

No words

Tumor NLRP3 Amplification Promotes Immunotherapy Resistance by Suppressing MHC Class I Expression https://www.medrxiv.org/content/10.1101/2025.10.06.25337175v1

Lactate impairs TLS formation - nice pre print www.biorxiv.org/content/10.1...

A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine

“Chris wasn’t even 10 and government funding was already working toward his cure. So, what are we risking in 30 years by cutting NIH funding? …that progress gave us the tools we needed to treat Chris the right way, up front, with the standard of care, since the science and trials had been done.”

One of my amazing patients who is in remission from MSI-H colorectal cancer after immunotherapy is featured!! I am so proud 🥹

It’s the difference between life & death. The wellness industry profits by creating distrust of medicine, falsely claiming “real” cancer cures are being hidden so doctors can keep patients sick & poison them with chemotherapy. They are lying to you. With fatal consequences. While making money. 3/

One of my amazing patients who is in remission from MSI-H colorectal cancer after immunotherapy is featured!! I am so proud 🥹

Former NCI official’s nonprofit seeks to tell the stories of cancer patients Patient Action for Cancer Research aims to show impact of federal research https://cancerletter.com/the-cancer-letter/20251003_1/

Early-onset gastrointestinal cancer is currently the most rapidly increasing early-onset cancer in the US. This JAMA Patient Page describes early-onset GI cancer and its risk factors, signs and symptoms, management, prognosis, and prevention measures. ja.ma/46BERoo

The Damage Done: @marianneguenot.bsky.social tells the story of clinical trials derailed by the administration's reckless science policy, across kidney disease, HIV, Alzheimer's disease, and cancer. Years of work and money thrown away, at times just short of a cure. www.nature.com/articles/s41...

Out now in #Science #Immunology: Zhenghai Tang (U of Macau) & André Veillette (@ircm.bsky.social / @mcgill.ca / @umontreal.ca) review the latest research on inhibitory #ImmuneCheckpoints in #cancer #immunotherapy. Check it out!

Screens not genes Such a good ad for colorectal cancer screening! www.usatoday.com/story/entert...

ICYMI: New online! Food as medicine in gastrointestinal cancer therapy

Early-onset colorectal cancer is expected to become the leading cause of #cancer death in ages 20 to 49 in the U.S. by 2030. Research is urgently needed to better detect and treat patients, argues this #SciencePerspective: https://scim.ag/3IfUgBA #WorldCancerResearchDay

We're thrilled to be here on BlueSky to bring you the latest practice-changing oncology research from all six JCO Journals! Follow-us for great content from #JCO, #JCOOP, #JCOGO, #JCOPO, #JCOCCI, & #JCOOA.

🧪🧪 Just a reminder, a 2024 study published in JAMA that included over 2 million children found that using acetaminophen, the active ingredient in Tylenol, during pregnancy was not associated with increased risk of autism, ADHD, or intellectual disability in children. jamanetwork.com/journals/jam...

Reading papers is a basic skill (and dare I say duty?) of scientists, and I include medical doctors in that group. Keeping abreast of the literature is a foundational part of our professions. There aren’t good shortcuts. In any case, reading papers regularly is fun. arstechnica.com/ai/2025/09/s...

Online now: A TLR4-dependent fibroblast-monocyte axis in tumor-draining lymph nodes contributes to metastasis in triple-negative breast cancer

Seriously one of my favorite characters in any show ever

Thanks Medscape for the opportunity to further the conversation on young onset gastrointestinal cancers by exploring possible causes, barriers to screening, and symptoms of concern. www.medscape.com/viewarticle/...

Just like there are good and bad macrophages..., there are good and bad NK cells!! This has profound therapeutic implications, far beyond oncology! Thanks to CD for highlighting both papers and the superb and efficient editorial work! Thanks to our collaborators (especially Zihai Li) and funders!

Online now: Oxidative-stress-induced telomere instability drives T cell dysfunction in cancer

As national medical, scientific, public health and patient organizations, we call for the resignation of HHS Secretary Robert F. Kennedy Jr. to ensure the health of the American people. Read our statement: asm.org/press-releas...

An ounce of prevention is worth a pound of something something

About this Florida vaccine story: When they were little - 1 yr and 3 1/2 - my two older boys, who’d had all their shots, got whooping cough. We asked their pediatrician what would’ve happened if they hadn’t been vaccinated. “Oh, they’d have died.”

Azelastine nasal spray shows promise as COVID prophylaxis, nice study of an over the counter agent. Still need vaccines, to be clear. jamanetwork.com/journals/jam...

Prasad has only been showing up at the FDA 3 days every 2 weeks. Prasad is commuting from CALIFORNIA. Notably the FDA is *paying for his travel* to and from California. In-person work for thee but not for me. www.wsj.com/politics/pol...

💯

What an incredible story of perseverance, this is the epitome of taking agency over one’s health. I hope she is able to continue her work. www.science.org/content/arti...

Action items: call your congressional reps and demand: 1) Kennedy needs to resign 2) Congress needs to investigate what’s happening at C.D.C. 3) ACIP (vaccinated advisory committee) cannot meet until expertise restored. Please reply with other important action items that you know about.

RFK jr must be removed (he shouldnt have been there in the first place) www.standupforscience.net/rfk-impeachm...

“‘She uncovered the social experience of women in science’ — the lab assistants who never became managers, the geologists poring over data in government offices while their male peers were doing fieldwork, those who despite their advanced degrees didn’t get hired or promoted, or who were sidelined…”

We are sadly going down the road of American Lysenkoism. www.nytimes.com/2025/08/30/o...

PSA: According to a pharmacist I know: If you live in one of the 34 states where a prescription for the COVID vaccine is NOT needed, you can just attest that you qualify to get it. The pharmacist will give it to you without investigation.

Some of the remarkably awful health effects of ultraprocessed food are clearly shown in this randomized trial: www.cell.com/cell-metabol...

I will never understand how American elites managed to convince themselves that uncivil debate — not fascism, not impunity and not widespread indifference to facts — is the defining problem of our time. www.nytimes.com/2025/08/26/o...

IDSA calls on insurers to cover COVID vaccines consistent with medical recommendations and evidence, and urges Congress to conduct strong oversight of the Administration’s decision restricting Americans’ freedom to choose vaccination. Our statement: https://bit.ly/3JBFPb6

I will be speaking and present for Q&A during Agenus’ webcast at 4pm EST. Log on soon and learn more about BOT/BAL in MSS Colorectal cancer #CRC Immunotherapy is finally making progress here, and now is time to push the envelope to bring about a brighter future, faster. lnkd.in/eZ-M8jA7

I don’t think non physicians realize how for real physicians, vaccines is a controversy like flat earth or creationism or birds aren’t real "No true Scotsman" actually holds here it's hard to really describe how baffling this is, how frustrating its been to see grow and how high the price will be

Americans consume more than half of their calories from ultra-processed foods. Children consumed more calories from ultra-processed foods than adults. abcnews.go.com/Health/ameri...

“Patriotism is not enough. I must have no hatred or bitterness for anyone.” A dose of wisdom from Edith Dawn over a hundred years ago #London