The FDA sent 18 warning letters to websites that illegally market unapproved and misbranded botulinum toxin (Botox) products, the agency announced. Read more at: https://www.medpagetoday.com/publichealthpolicy/fdageneral/118329?trw=no

Physician groups were generally dissatisfied with the final 2026 Medicare Physician Fee Schedule rule released late last week by the Centers for Medicare & Medicaid Services (CMS). Read more at: https://www.medpagetoday.com/publichealthpolicy/medicare/118333?trw=no

Medicare will cover semaglutide (Wegovy) and tirzepatide (Zepbound) for their weight management indications for people with obesity, President Trump announced on Thursday. Read more at: https://www.medpagetoday.com/publichealthpolicy/medicare/118344?trw=no

Use of GLP-1 receptor agonists was associated with a lower risk of mortality for dialysis patients with type 2 diabetes, according to a retrospective cohort study of Medicare enrollees. Read more from our coverage of #OW2025: https://www.medpagetoday.com/meetingcoverage/obesityweek/118321?trw=no

For Inside Medicine, MedPage Today Editor-in-Chief Jeremy Faust, MD, MS, MA, examines the peer review system at the CDC and how it has been "quietly dismantled." Read more at: https://www.medpagetoday.com/opinion/faustfiles/118330?trw=no

Maine's largest health system sent letters to hundreds of patients about their deaths. Those patients were alive enough to read them. Read the full story at: https://www.medpagetoday.com/hospitalbasedmedicine/generalhospitalpractice/118305?trw=no

"Approximately 70 million people worldwide use sign language to communicate. However, many clinicians have limited understanding of ASL or deaf culture." Read the #OpEd from fourth-year medical student Annie Hutchinson at: https://www.medpagetoday.com/opinion/second-opinions/118309?trw=no

Moderate to severe obstructive sleep apnea (OSA) independently correlated with development of cerebral microbleeds seen on brain MRI that are linked to stroke and dementia risk, a longitudinal cohort study showed. Read more at: https://www.medpagetoday.com/pulmonology/sleepdisorders/118302?trw=no

Facility-based colorectal cancer screening among young adults has rapidly increased since U.S. guidelines started recommending that screening begin at an earlier age, according to a population-based cohort study. Read more at: https://www.medpagetoday.com/gastroenterology/coloncancer/118307?trw=no

Investigational gefurulimab met its primary efficacy endpoint in adults with anti-acetylcholine receptor (AChR) antibody-positive generalized myasthenia gravis (MG), topline data from the phase III PREVAIL trial showed. https://www.medpagetoday.com/meetingcoverage/aanem/118297

Canadian patients with spondyloarthropathies aren't being treated adequately, a registry study suggested, with something like half still showing active disease after spending a year on their most recent therapy. https://www.medpagetoday.com/rheumatology/arthritis/118300

Urinary albumin-creatinine ratio may be slightly better than urinary protein-creatinine ratio at predicting kidney failure-related clinical outcomes in chronic kidney disease, a patient-level meta-analysis suggested. https://www.medpagetoday.com/nephrology/generalnephrology/118295

The number of daily steps associated with slower Alzheimer's disease progression was a goal many older adults could reach, data from the Harvard Aging Brain Study suggested. Read more at: https://www.medpagetoday.com/neurology/alzheimersdisease/118292?trw=no

Givinostat (Duvyzat) had a manageable long-term safety profile in Duchenne muscular dystrophy, data from an open-label extension study suggested. https://www.medpagetoday.com/meetingcoverage/aanem/118270

Though the percentage of U.S. teenagers who vape nicotine has declined in recent years, daily vaping among those already doing so increased, as did unsuccessful quit attempts, a cross-sectional study suggested. https://www.medpagetoday.com/pediatrics/generalpediatrics/118294

State laws aimed at protecting the healthcare industry from corporate influence do not seem to be working, at least with regard to fertility clinics, an analysis of CDC data found. ⬇️

Public health workers must help deliver wins at the state level, educate the judiciary, and work to depoliticize health, experts and former HHS officials said during a panel discussion at the @apha.org annual meeting. Read more from #APHA2025 at: www.medpagetoday.com/meetingcover...

The American Nurses Association (ANA) applauded the Joint Commission's latest hospital performance goals, which elevated the issue of nurse staffing and linked it to patient safety. Read more at: https://www.medpagetoday.com/nursing/nursing/118290?trw=no

The Centers for Medicare & Medicaid Services on Friday finalized its annual physician fee schedule for 2026, giving doctors treating Medicare patients a 3.77% pay bump if participating in APMs and a 3.26% increase for those not participating in APMs. www.medpagetoday.com/publichealth...

"There are already enough barriers pushing marginalized students out of medicine. Let's make sure hunger isn't one of them." In an #OpEd, second-year MD-PhD student Naa Asheley Ashitey discusses the impact of SNAP benefit cuts. https://www.medpagetoday.com/opinion/second-opinions/118288?trw=no

The FDA approved doxecitine and doxribtimine powder (Kygevvi) for thymidine kinase 2 deficiency (TK2d), an ultra-rare mitochondrial depletion syndrome. https://www.medpagetoday.com/genetics/generalgenetics/118289

Two studies demonstrated the benefits of treating juvenile myasthenia gravis with newer drugs. #AANEM2025 https://www.medpagetoday.com/meetingcoverage/aanem/118275

The investigational complement-targeting agent claseprubart was safe and led to significant improvements in generalized myasthenia gravis (MG), the phase II MaGic trial showed. #AANEM2025 https://www.medpagetoday.com/meetingcoverage/aanem/118269

Egg donors may receive different treatment based on which commercial egg bank they're working with and if the eggs are intended for fresh or frozen transfer, according to two national data analyses. @asrmorg.bsky.social #ASRM2025 www.medpagetoday.com/meetingcover...

Thank you to MedPage Today for giving me a place to share this op-ed and important topic. @medpagetoday.com @gfriedman.bsky.social www.medpagetoday.com/opinion/seco...

An implantable autologous cell therapy led to higher remission rates compared with standard surgical care in patients with persistent Crohn's perianal fistulas who had failed prior treatments, the randomized phase II STOMP2 trial showed. https://www.medpagetoday.com/meetingcoverage/acg/118262

Despite previous concerns, a single infusion of the #NSAID ketorolac alongside standard analgesics was a safe and efficacious pain control option after egg retrieval, a double-blind randomized trial found. @asrmorg.bsky.social #ASRM2025 www.medpagetoday.com/meetingcover...

Fired members of the CDC's ACIP have given their replacements a failing grade. 🚨⬇️

In this week's #NursesStation, Northeastern University Dean of Nursing Amanda Choflet asks nurses about how their facilities have prepared for the presence of ICE agents. Join the conversation at: https://www.medpagetoday.com/nursing/nurses-station/118273?trw=no

Exposure to SARS-CoV-2 infection in utero was associated with an increased risk of neurodevelopmental diagnoses among children by age 3 years, according to a retrospective cohort study. Read more at: https://www.medpagetoday.com/infectiousdisease/covid19/118268?trw=no

What we heard this week ⬇️ #MedSky "It felt like that might be a shot across the bow." -- Aaron Carroll, MD, MS, president and CEO of @academyhealth.bsky.social, on a recent Fox News article that criticized the U.S. Preventive Services Task Force as too "woke." www.medpagetoday.com/primarycare/...

"This one-two punch of executive branch rhetoric coupled with state-level litigation is not a coincidence." Read the full #Oped from attorney and advisor in the biopharma sector Richard Hughes IV, JD, MPH at: https://www.medpagetoday.com/opinion/second-opinions/118266?trw=no

Immunization against COVID-19, respiratory syncytial virus (RSV), and influenza effectively and safely reduced the risk of severe outcomes in people of all ages, according to a systematic review of 511 studies. Read more at: https://www.medpagetoday.com/infectiousdisease/vaccines/118239?trw=no

Use of hormonal contraceptives was associated with an increased risk of breast cancer, but the risk varied by progestin content, according to a large Swedish cohort study. https://www.medpagetoday.com/hematologyoncology/breastcancer/118243

A sustained reduction in deaths from prostate cancer was observed with prostate-specific antigen (PSA) testing in long-term follow-up results from the European Randomized Study of Screening for Prostate Cancer. https://www.medpagetoday.com/hematologyoncology/prostatecancer/118218

Regular "moderate-level" exercise appeared to achieve optimal risk reduction for digestive system cancers, according to a new analysis of three large prospective cohorts. https://www.medpagetoday.com/primarycare/exercisefitness/118232

An investigational live attenuated vaccine led to protection against Salmonella enterica serovar Paratyphi A infection, according to a phase IIb randomized trial using a controlled human infection model. https://www.medpagetoday.com/infectiousdisease/vaccines/118257

Combining in-clinic physical therapy with home exercise did not lead to greater reductions in knee pain for patients with degenerative meniscal tear, a randomized trial showed. https://www.medpagetoday.com/painmanagement/painmanagement/118217

Disparities in insurance coverage for fertility preservation may explain racial differences in egg freezing rates, a retrospective cohort study found. Read more from our coverage of the @asrm_org annual congress at: https://www.medpagetoday.com/meetingcoverage/asrm/118240?trw=no

Young men tolerated the anal administration of a liquid with a high capacity for oxygenation -- good news for researchers who are developing a rectal ventilation system for patients in respiratory failure. Read more at: https://www.medpagetoday.com/criticalcare/generalcriticalcare/118231?trw=no

Intravenous efgartigimod (Vyvgart) met its primary endpoint in adults with acetylcholine receptor antibody-negative myasthenia gravis, the ADAPT SERON trial showed. https://www.medpagetoday.com/meetingcoverage/aanem/118255

Descartes-08, an autologous, B-cell maturation antigen (BCMA)-directed mRNA chimeric antigen receptor (CAR) T-cell therapy, led to sustained responses in generalized myasthenia gravis, a phase IIb trial showed. https://www.medpagetoday.com/meetingcoverage/aanem/118230

"Ultimately, the employment shift is not the end of physician community -- it's a call to redesign it." In an #OpEd, the authors argue that it's time to adapt to the employed physician era. Read more: https://www.medpagetoday.com/opinion/second-opinions/118254

Gutting funding for key health agencies & terminating thousands of workers does nothing to ensure the future of the biotech industry, experts & Democratic lawmakers argued during a Senate health committee hearing on Wednesday. @akesselheim.bsky.social Read more: www.medpagetoday.com/washington-w...

Self-reported symptoms from eating gluten or wheat are common around the world in individuals without celiac disease or wheat allergy, a meta-analysis showed. Read more at: https://www.medpagetoday.com/allergyimmunology/allergy/118183?trw=no

Estetrol (E4) -- one of four natural estrogens -- significantly reduced the weighted weekly score of moderate-to-severe vasomotor symptoms in postmenopausal women, according to an analysis of two phase III trials. Read more at: https://www.medpagetoday.com/meetingcoverage/tms/118172?trw=no

HHS scrapped yet another meeting of the U.S. Preventive Services Task Force (USPSTF), sources told MedPage Today. ⬇️

For women over 35 considering #fertility preservation, freezing their eggs as soon as possible may be vital for increasing the probability of having at least one live birth, a retrospective cohort study found. #ASRM2025 @asrmorg.bsky.social www.medpagetoday.com/meetingcover...

What should researchers do about "junk science"? @drkatiesuleta.bsky.social has spent the past 15 months trying to have a flawed autism case study retracted -- revealing how junk science continues to persist in the scientific record. Read the #OpEd: www.medpagetoday.com/opinion/seco...

Hitting rheumatoid arthritis early and hard, with targeted therapies as first-line treatment, appears to reduce the likelihood that it will reach the dreaded "difficult-to-treat" stage, according to studies. https://www.medpagetoday.com/meetingcoverage/acr/118195