Balanced polymorphism in a floral transcription factor underlies an ancient rhythm of daily sex alternation in avocado https://www.biorxiv.org/content/10.64898/2025.12.22.695989v1

RepeatMasker 4.2.3 released! Fixes a sensitivity issue affecting staged searches in Rodentia species and adds support for BGZIP input files without in-place decompression. More details www.repeatmasker.org

RNA decay via the nuclear exosome is essential for piwi-mediated transposon silencing https://www.biorxiv.org/content/10.64898/2025.12.16.694471v1

Oh to be a little Tardigrade walking across a microscopic slide. 🫧🐻🧪

Can one map the genome-wide binding (1) and its protein partners (2) simultaneously from the same sample? Yes, one can. with CUT&ID ✂️🪪 Spearheaded — singlehandedly — by @annanordin.bsky.social No need of transgenesis, cloning and overexpression. Check it out, it's fast and its works.

The first paper of my PhD is now available as a preprint! 🎉 Transposable elements (TEs) don't just jump within fungal genomes, they also move extensively between species. In this study, we screened over 1,300 fungal genomes and found a conservative estimate of 5,500+ horizontal transfer events.

The story of how multiple RBPs cooperate to repress translation is now out in @cp-cellreports.bsky.social by @marcopayr.bsky.social and in a great collaboration with @hennig-lab.bsky.social! www.cell.com/cell-reports...

It's great to see Radiohead live for the first time after listening to them since middle school. Too bad we didn't hear Everything in its Right Place and Karma Police today, but the setlist was still very good😊

Not a huge fan of gtf and gff, because I had to deal with these formats and face the repercussions, but still a very nice thread!

It's insane that my hobby drives me up the freaking wall.

Great culture can save lives. Literally. Amazing letter in today’s @thetimes.com about Tom Stoppard

R: We might as well be dead. Do you think death could possibly be a boat? G: No, no, no... Death is...not. Death isn't. You take my meaning. Death is the ultimate negative. Not-being. You can't not-be on a boat. R: I've frequently not been on boats. G: No, no, no--what you've been is...not on boats

Coexistence of piRNA and KZFP Defense Systems: Evolutionary Dynamics of Layered Defense against Transposable Elements https://www.biorxiv.org/content/10.1101/2025.11.27.690821v1

Entire creation of new data that has no bearing upon any histological relevance. Remember LLM models are not open and we have no understanding of what NeuN, GFAP, or DAPI means in biological space within the LLM. This is nonsense. But it looks at first blush as "real" to the uninformed. Scary.

Another AI cover art. Sigh

🧬 PhD Position: Evolutionary & Comparative Genomics 🕷️ Join us at @uni-goettingen.de for a 3-year PhD (65% TV-L E13). We will investigate the genomic & phenotypic impact of gene duplication across 233 arthropod genomes! More infos 👇 and s.gwdg.de/eDrAAY #Evolution #Genomics #Bioinformatics

Why are some reviewers so confidently nasty? Is it necessary to be like that?! Don’t they understand how much work goes into each manuscript and how damaging it can be for some people to read the vitriol? Or even consider that they might be wrong?!

A bittersweet acceptance: Between a manuscript and grief Stefanie Williams @sillysciencelady.bsky.social shares the story behind her paper on the synaptonemal complex, including a tribute to her supervisor Scott Hawley, who passed away while Stefanie was completing the research.

Feed for posts about drosophila. Tag #Drosophila or #FruitFly to be included. bsky.app/profile/did:...

WE ARE RECRUITING PHD STUDENTS!!! We have three(!) funded PhD studentships advertising presently. If any of these are of interest, please reach out! Thread below with links to more information on each project. #Drosophila #Evolution #Immunity #SelfishGene #Aphids Thread with links below 🧵 1/4

Awesome paper from Kathy Collins' lab Different repair pathways support intact or truncated insertions by R2 retrotransposon protein | Science www.science.org/doi/10.1126/...

.DS_Store👻😘🥳

TEs aren’t just genomic parasites, they’re also engines of genomic novelty. Our new study with ~2,000 Z. tritici genomes shows repeated TE mobilization waves during global expansion. With @danielcroll.bsky.social & @guidopuccetti.bsky.social 🧬 www.nature.com/articles/s41... #TEworldwide

Extremely important effort and call for action for researchers everywhere! Bravo, Mark and co!

Excited to share our new preprint on BioRxiv! A collaborative effort spanning many years and several labs to uncover what the germline chromosomes of Paramecium really look like. 🔗 www.biorxiv.org/content/10.1... 1/5

2-factor authentication required ⬇️ 😊

My awesome grad student Shashank and I wrote this paper trying to look at broader patterns of HT in TEs. HT is happening everywhere! DNA transposons jump further than other classes! www.biorxiv.org/content/10.1...

Happy Halloween 🎃👻💀 from the crypt-keeper wasp, who lays its eggs into a crypt created by its host, then manipulates the host’s behavior for its own benefit, before devouring it from the inside out and emerging through its face! en.wikipedia.org/wiki/Euderus...

I've been asked about this paper (www.nature.com/articles/s41...) enough times that I finally had to read it. The basic claim is that mRNA vaccines had huge synergistic benefit with checkpoint blockade against lung cancer melanoma. tl;dr it's glam-slop & everyone involved should be embarrassed

Behold, my new favorite type of plot: roadkill

Funders must recognise that great discoveries often come from studies that seeks to advance knowledge for its own sake go.nature.com/47zrzYZ

Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️ Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...

🚨Hiring a 2yr postdoc in the lab work on muscle biology, genomics & ALS. Expertise in the above advantageous, but work ethic, desire to learn/develop and being a good scientist/person more important Good collab with @droch.bsky.social so travel to CPH involved as well www.kcl.ac.uk/jobs/126245-...

if you see this post, your actions are: - if you have a spare buck, give it to Wikipedia, then repost this - if you don't have a spare buck, just repost your action is mandatory for the world's best source of information to survive

Please share/repost widely: I have a postdoc position available. Please see ad below and reach out to apply. academicpositions.harvard.edu/postings/15449

Not today, parasitic #wasps!✋🚫 #Stinkbugs use a fungus-carrying organ on their hind legs to coat their eggs in #fungi🍄🦵 This provides a physical defense against #parasitic wasp oviposition🛡️ www.science.org/doi/10.1126/...

A lot of pressure on the different grant schemes, and pretty much independent of career stage.

Many questions remain about how these patterns emerge and how the right piRNA precursors are selected, but that's a story for another day ;-). For now, check out the story and explore the genome yourself. We'd love to get your feedback! (11/12) www.biorxiv.org/content/10.1...

Hi bioinformatics, genomics and CS friends! Please help me spread the word. I'm hiring a postdoc! Come work on cutting edge method development in algorithmic genomics with me and my group at @umdscience.bsky.social! 🖥️🧬

PREACH! www.nature.com/articles/s41...

I maintain that the most important is the coffee machine

My HPLC was definitely overlooked www.nature.com/articles/d41...

I've heard some bizarre takes, but this one takes the prize (apparently, together with the word processor that was used to write it) www.nature.com/articles/d41...

🚀 New on the Bioconductor Blog: GPU Support in Bioconductor Bioconductor is building better support for GPU-accelerated package development for faster and more scalable analysis workflows Learn how package maintainers can leverage this new GPU infrastructure: blog.bioconductor.org/posts/2025-1...

We’re excited to report work led by postdoc Jennifer Porat in the lab, finding that DNA accumulates on the surface of living cells and that the secreted extracellular protein DNASE1L3 can modulate its levels on B and T cells. With a new twist for ATAC-seq as well www.biorxiv.org/content/10.1...

Nowadays, too many institutions thinking ‘if we build it they will come’ combined with a shortsighted research funding model, a saturated Phd training sector, bloated admin load, and a general decline in creativity. Tough times indeed!

Today I am so pleased to present our work on how chromatin remodelers affect mesoscale chromatin organization. www.science.org/doi/10.1126/...

Yes, yes, Europe has its benefits. Walkable cities. Cultural heritage. Amazing food. Little gun violence. Healthcare. Governments that are not shut down. But the number of website pop-ups asking one to accept cookies renders the continent pretty much unlivable.

It feels great to close 3 powerpoints, 10 word documents and 57 browser tabs after submitting the grant😌