Kicked off a series on #Drosophila TE discovery and naming. The first post covers elements that predate the term "mobile element", and more. artemilin.dev/posts/te_nam...

A ring of cells deforms into a triangular keyhole in just 15 minutes. Meet the hindgut, a model for boundary-driven morphogenesis! Out now in @pnas.org at doi.org/10.1073/pnas... with @zhaoshh.bsky.social, Alex Jacinto, Eric Wieschaus, Stas Shvartsman, @lepuslapis.bsky.social (1/8)

Hi! We are looking for a PhD to work on the cross talk between transposable elements, insects and intracellular bacteria on the bioinformatics side. The PhD would be supervised by @mariefablet.bsky.social and myself along with @nicolasparisot.bsky.social Deadline December 2025! Please share! #tesky

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The papers that I enjoyed reading this week, especially the second one: artemilin.dev/posts/202509...

This gorgeous fella landed on my knee last week when I was in Vienna, chilled for a bit, didn't mind me touching him at all and then disappeared. Can anyone help identify? I would say that his length wasn't exceeding 6-7 mm. #entomology

Living organisms are assumed to produce same-species offspring. A study in Nature reports a shift from this norm in Messor ibericus, an ant that lays individuals from two distinct species. go.nature.com/3V68MP0 🧪

Together with @soreklab.bsky.social, our labs discovered that the human cGAS-STING pathway evolved from ancient bacterial proteins in CBASS anti-phage defense www.nature.com/articles/s41... www.nature.com/articles/s41... www.nature.com/articles/s41...

Hoher Dachstein, 2997 m, no sherpas, no oxygen. (Don't mind the cable car)

In all my obsession with RNA silencing, I realized I became blind to the significance of autoregulation of DNA transposons. Which is funny, because it was characterized in many ways by my Ph.D. advisor. From 2013: elifesciences.org/articles/00668

Translational research is digging for gold. Basic research is learning where and what to dig. The more funding is diverted to translation, the more we deplete the research ecosystem, driving the supplies of "gold" - immediately translatable findings and innovations - to unsustainably low levels.

DNMT3Beauty

#TEsky #RNAsky #RNAbiology

Climate models since the 1970s nailed it—most predicted global warming almost exactly as it happened.

I don't know the exact number of Nobel Prize laureates who wrote cooking books, but here's a rösti recipe from Christiane Nüsslein-Volhard: artemilin.neocities.org/post/250817_nv

We are hiring a lab technician! Join our group studying signaling networks in #Drosophila, with a possibility to carry out a research project. Please RT. Job posting: employmentopportunities.umb.edu/boston/en-us... Veraksa lab website: www.faculty.umb.edu/alexey_verak...

I'm starting to think that conda isn't the best option for isolated environments. I have just 7 envs, some of which run a couple of dedicated tools and the number of files required to run them is gigantic. Mind you, today, the large file number exerts much harder strain on storage than the file size

🔬 From our August issue (rupress.org/jcb/issue/22...): A confocal image of a #Drosophila egg chamber where #actin filaments are labelled with rhodamine phalloidin and color-coded to represent different depths within nurse cells. From Ghosh et al.: rupress.org/jcb/article/...

Did you know #fruitflies ovulate roughly 70 times a day? This makes #Drosophila a powerful model for studying the #genetics behind #ovulation in humans. Here's a stunning look at fly ovaries under a #fluorescent microscope. Each blue dot is a cell nucleus. The beauty of #DrosophilaOogenesis!

It's so much easier to destroy than to build, and the U.S. admin once again proves it has firmly stepped onto the path of total scientific destruction

Casual reminder that you can use spring to compress your raw basecalled sequencing data even more than by using gzip or bz2. Save some space for bams!

piRNAs are essential for transposon silencing in the animal germline. But how do hosts trap transposon sequences in genomic loci that help establish a piRNA response? Looking at a natural transposon invasion, Baptiste Rafanel and Kirsten Senti made some remarkable observations.

Previous studies of extrachromosomal circular DNA #eccDNA in #plants are based on short-read seq. @vanderschuren-lab.bsky.social uses long-read seq to obtain a map of full-length eccDNAs from #Arabidopsis, identifying their genomic origins & epigenetic regulation @plosbiology.org 🧪 plos.io/44Mq3RI

Colossal BS is getting even shadier

1/4 Okay, this is actually crazy. Let's deconstruct the paper. 1. Authors showed that mites feeding on fly eggs and larvae "acquired" P-element DNA. The same mites assoc. w/ flies lacking P, did not have P. 2) They ruled out the contamination with medium and showed that common mites,

My full gallery of turtle ants is here:

I need you, and I can't stress this enough, to read this paper by Margaret Kidwell et al. on horizontal transfer of P elements from mites to flies and back...from *1991*: www.science.org/doi/10.1126/...

Grateful to @mannerviklab.bsky.social and @biologsp.bsky.social for hosting a nano-scCUT&Tag workshop for all @scentinel.bsky.social partners. Amazing tour at @scilifelab.se and wonderful hospitality by the Sweds...they did spoil us! missing the cool summer weather and the calmness of Stockholm...

It's interesting that other Bel/Pao family TE, Copia, forms full fledge viral particles (also, a LOT of them) but here I saw nothing about gag function of 3S18. Is it dispensable? Do any particles form at all?🤔

Second call for postdoc positions in the lab. Please follow the link below to apply or get in touch for further information. mbg.au.dk/aktuelt/ledi...

🖥️🧬 The University of Innsbruck is offering PostDoc fellowships for women: www.uibk.ac.at/en/research/... Do you have a strong plan for a bioinformatics project (e.g. spatial/single-cell/multiomic data analysis, AI for oncology, immunogenomics)? I would be happy to support you with your application!

Very happy to share our protocols paper for CELLO-seq. This will make single cell long read RNA-seq more accessible and provides analysis guidelines. We hope this helps the #transposon #TEsky community and folks working on #singleCell isoform and allelic #gene expression. doi.org/10.1038/s415...

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Hi, if you are looking to come to Canada for a post-doc or a PhD, consider my lab to study the genetic basis of social interactions, using the fruit fly! My university (Western University) has a new program to welcome you! See below! #drosophila #postdoc #canada #PhD #social #behaviouralneurogenetic

I can't believe this only ended up getting 3,590 supporters when it needed 10,000; it was a sad day. This has unlocked a new fixation, and I will campaign to get this reopened... #Drosophila #Tribolium #CoolScience #FruitFlies beta.ideas.lego.com/product-idea...

The irony was not lost on me

Grundtvigs kirke left me speechless

You think P-element was the latest TE invasion in #Drosophila melanogaster? Think again! #TEsky

Latest in #G3journal: Cytological studies revealed that ELYS, a conserved nuclear pore complex subunit in #Drosophila, is involved in the apposition of female and male pronuclei, affecting the parental genome configuration of the first mitotic spindle during fertilization. buff.ly/68yqGrg

To be or not to be 🤴💀: read how hamlet orchestrates the assembly of adult male reproductive system in #Drosophila in a new paper from our colleagues! Led by Huazhen Wang, a PhD student in Qi Dai group, the study explores how this protein mediates the fusion of testis and supportive gonadal tissue

Sometimes, I have wicked thoughts about piRNA field being exhausted at this point, but then I see papers like this and am proven that it's alive and kicking. Kudos to authors for not naming a new factor Obelix or Pumpkin. www.pnas.org/doi/10.1073/...

We wrote a review on Transposable Elements (TEs) and almost all aspects of TE silencing and their roles in biological processes & disease. www.nature.com/articles/s41...

About half of C. elegans genes have unknown functions. There isn’t even an agreement on how many genes humans have and I believe most human genes remain uncharacterised with only anecdotal evidence for a specific function. So yeah, go play with your virtual cell and all.

I love this figure. The outer circle of dots represents TE insertions shared with the drosophila reference genome and all the three circles below show the non-reference insertions. No hot spots (on average for all TE families, though), no preference for heterochromatin. Amazing.

The Chromatin And Development lab are hiring a postdoc! Come join us; we are a happy and hard working team @mrc-lms.bsky.social in London UK. Projects span the intersection of chromatin and transposon biology in dev't and disease. Email/DM for more info. Pls RT! lms.mrc.ac.uk/work/vacanci...

I am looking for a new postdoc to join the lab. Interested in pluripotency, germ cells, and in investigating these in a genetically tractable cnidarian? Get in touch! We offer a long-term contract, excellent research environment, and a lovely city #Galway. www.urifranklab.org

Postdoc positions open in my lab (Francis Crick Institute) to study 1. initiation of DNA replication. 2. chromatin replication/epigenetic inheritance. Great for biochemists, biophysicists and cryo-EM/cryo-tomography scientists. Deadline 3 August 2025. crick.wd3.myworkdayjobs.com/External/job...

Postdoc🚨! Come join our HFSP team to uncover how chromatin moves in cells and what this means for genome function! Great opportunity to combine single-cell genomics, live imaging and polymer physics in the unique mammalian retina with @andersshansen.bsky.social, Davide Michieletto & Sandra Tenreiro

Come join us in beautiful Stockholm! You'll have a chance to experience good pastry🧁🍰 and great science 🧪🧬! Share, repost, spread the word!