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Time to share some data that might get buried in the supplement of our recent paper here rdcu.be/e91Kj Here you can see how cells intercalate in a coordinated fashion. They move from a double rowed organisation to a single row stalk. 🧵

Batch-22

Join us in Heidelberg for your PhD! If you are excited about CRISPR genome engineering and would like to develop and apply new methods to investigate Wnt signaling in different model systems, than this project is for you. More info here: my-hbigs.uni-heidelberg.de/site/index.p... 🧪🧬🔬

Surprisingly, a very good analogy😁

Want to know how histone marks regulate your favorite gene? Go single molecule with ChromSMF: integrated measure of chromatin accessibility and histone marks + DNA methylation, TF footprints and genotype for free! Very proud of @mpalamin.bsky.social ! @embl.org

Excited to share my PhD work! The question: How is genome organization established? Here, we developed a low-input Micro-C method, Pico-C, and used it to map chromatin architecture across early stages of fly development. Here’s a quick Blue-torial 🙂 (1/n) www.nature.com/articles/s41...

🔬 Recruiting a Postdoc!!!! I’m looking for a motivated postdoc to join my lab and work on characterizing the role of a heterochromatin protein involved in a sex-ratio meiotic drive system in Drosophila. If you know someone who might be interested, please share widely!

Postdoc positions available in my lab in Aarhus, Denmark on 'Mammalian Nuclear RNA Production and Turnover Systems'. Please get in touch for further information or simply apply here: mbg.au.dk/en/news-and-...

Can't wait to release a 10-year-old birthday version for SeqKit! - 10 years - 2 papers, 3500 citations - 20 contributors - 40 subcommands - 880 commits - 500 issues - 685.5K Bioconda total downloads Thank you all, dear contributors and users! I'll keep maintaining it. github.com/shenwei356/s...

"Nobody will care about your work about sugar metabolism and transporters in Neurospora crassa" Nobody can predict what can happen with your work. www.sciencedirect.com/science/arti...

#Drosophila calling. Delighted to share our new collection of ShineGAL4 drivers for CNS, FB, muscles, enterocytes, oenocytes and MTs made by @vgirard.bsky.social, @sebsorge.bsky.social and colleagues @crick.ac.uk. All at Bloomington @bdsc.bsky.social @dev-journal.bsky.social tinyurl.com/4jpw9jd6

You still have 3 days to apply to the postdoc positions available in my lab 😀 🔬Come and work with us 🔬

Not something you see in textbooks very often: tripolar mitosis.

This is a beautiful case of how real science happens & serious scientists work. Kudos to both set of authors: “This has been a humbling experience, but one that speaks to the self-correcting nature of the scientific endeavor.” www.science.org/doi/10.1126/...

One protein. One pathway. A whole germline fate. New paper from my postdoc @mpi-bio-fml.bsky.social out in PNAS: Germline fate determination by a single ARGONAUTE protein in Ectocarpus www.pnas.org/doi/10.1073/...

I'm sorry

I am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!

Ok, it's time to spill some tea🫖

It’s out! Using cryo-ET in Dicty cells, we take a fresh in situ look at vaults. Surprisingly, we uncover vaults associated with ER and NE membranes, and find that many vaults enclose ribosomes in defined orientations, opening new avenues to their cellular function! www.biorxiv.org/lookup/conte...

Make a Bond movie academic The World Is Not Enough: Increased frequency of microplastic clusters detection among Low Earth Orbit debris

Balanced polymorphism in a floral transcription factor underlies an ancient rhythm of daily sex alternation in avocado https://www.biorxiv.org/content/10.64898/2025.12.22.695989v1

RepeatMasker 4.2.3 released! Fixes a sensitivity issue affecting staged searches in Rodentia species and adds support for BGZIP input files without in-place decompression. More details www.repeatmasker.org

RNA decay via the nuclear exosome is essential for piwi-mediated transposon silencing https://www.biorxiv.org/content/10.64898/2025.12.16.694471v1

Can one map the genome-wide binding (1) and its protein partners (2) simultaneously from the same sample? Yes, one can. with CUT&ID ✂️🪪 Spearheaded — singlehandedly — by @annanordin.bsky.social No need of transgenesis, cloning and overexpression. Check it out, it's fast and its works.

The first paper of my PhD is now available as a preprint! 🎉 Transposable elements (TEs) don't just jump within fungal genomes, they also move extensively between species. In this study, we screened over 1,300 fungal genomes and found a conservative estimate of 5,500+ horizontal transfer events.

The story of how multiple RBPs cooperate to repress translation is now out in @cp-cellreports.bsky.social by @marcopayr.bsky.social and in a great collaboration with @hennig-lab.bsky.social! www.cell.com/cell-reports...

It's great to see Radiohead live for the first time after listening to them since middle school. Too bad we didn't hear Everything in its Right Place and Karma Police today, but the setlist was still very good😊

Not a huge fan of gtf and gff, because I had to deal with these formats and face the repercussions, but still a very nice thread!

It's insane that my hobby drives me up the freaking wall.

Great culture can save lives. Literally. Amazing letter in today’s @thetimes.com about Tom Stoppard

R: We might as well be dead. Do you think death could possibly be a boat? G: No, no, no... Death is...not. Death isn't. You take my meaning. Death is the ultimate negative. Not-being. You can't not-be on a boat. R: I've frequently not been on boats. G: No, no, no--what you've been is...not on boats

Coexistence of piRNA and KZFP Defense Systems: Evolutionary Dynamics of Layered Defense against Transposable Elements https://www.biorxiv.org/content/10.1101/2025.11.27.690821v1

Entire creation of new data that has no bearing upon any histological relevance. Remember LLM models are not open and we have no understanding of what NeuN, GFAP, or DAPI means in biological space within the LLM. This is nonsense. But it looks at first blush as "real" to the uninformed. Scary.

Another AI cover art. Sigh

🧬 PhD Position: Evolutionary & Comparative Genomics 🕷️ Join us at @uni-goettingen.de for a 3-year PhD (65% TV-L E13). We will investigate the genomic & phenotypic impact of gene duplication across 233 arthropod genomes! More infos 👇 and s.gwdg.de/eDrAAY #Evolution #Genomics #Bioinformatics

Why are some reviewers so confidently nasty? Is it necessary to be like that?! Don’t they understand how much work goes into each manuscript and how damaging it can be for some people to read the vitriol? Or even consider that they might be wrong?!

A bittersweet acceptance: Between a manuscript and grief Stefanie Williams @sillysciencelady.bsky.social shares the story behind her paper on the synaptonemal complex, including a tribute to her supervisor Scott Hawley, who passed away while Stefanie was completing the research.

Feed for posts about drosophila. Tag #Drosophila or #FruitFly to be included. bsky.app/profile/did:...

WE ARE RECRUITING PHD STUDENTS!!! We have three(!) funded PhD studentships advertising presently. If any of these are of interest, please reach out! Thread below with links to more information on each project. #Drosophila #Evolution #Immunity #SelfishGene #Aphids Thread with links below 🧵 1/4

Awesome paper from Kathy Collins' lab Different repair pathways support intact or truncated insertions by R2 retrotransposon protein | Science www.science.org/doi/10.1126/...

.DS_Store👻😘🥳

TEs aren’t just genomic parasites, they’re also engines of genomic novelty. Our new study with ~2,000 Z. tritici genomes shows repeated TE mobilization waves during global expansion. With @danielcroll.bsky.social & @guidopuccetti.bsky.social 🧬 www.nature.com/articles/s41... #TEworldwide

Extremely important effort and call for action for researchers everywhere! Bravo, Mark and co!

Excited to share our new preprint on BioRxiv! A collaborative effort spanning many years and several labs to uncover what the germline chromosomes of Paramecium really look like. 🔗 www.biorxiv.org/content/10.1... 1/5

2-factor authentication required ⬇️ 😊

My awesome grad student Shashank and I wrote this paper trying to look at broader patterns of HT in TEs. HT is happening everywhere! DNA transposons jump further than other classes! www.biorxiv.org/content/10.1...

Happy Halloween 🎃👻💀 from the crypt-keeper wasp, who lays its eggs into a crypt created by its host, then manipulates the host’s behavior for its own benefit, before devouring it from the inside out and emerging through its face! en.wikipedia.org/wiki/Euderus...

I've been asked about this paper (www.nature.com/articles/s41...) enough times that I finally had to read it. The basic claim is that mRNA vaccines had huge synergistic benefit with checkpoint blockade against lung cancer melanoma. tl;dr it's glam-slop & everyone involved should be embarrassed