📃 New paper alert! The Zychlinsky Lab and @raunser-lab.bsky.social identified the first protein that converts chromatin into an immune effector: Myeloperoxidase transforms chromatin into neutrophil extracellular traps. Now published in @nature.com: www.nature.com/articles/s41...

Excited to share our new publication, out today in Nature! www.nature.com/articles/s41.... @kanchanj.bsky.social led this fascinating fungal-bacterial interaction project. We are grateful for our wonderful collaborators Brian Peters and David Underhill.

Check out our new preprint Metabolic imprinting drives epithelial memory during mucosal #fungal infection. Thanks to all collaborators www.biorxiv.org/content/10.1...

CDC employees standing up and walking out in light of the mass shootings, firings, and *waves hands in the air* everything else. #USAnotRFK Lets gooooo

New: In 7 months, Kennedy has broken the CDC, perhaps irreparably. For all he’s done with mass firings, gutting expertise, and attacking vaccines, Wednesday’s loss of its most senior and competent leaders—truly the CDC’s backbone—is the most consequential attack yet. www.msnbc.com/msnbc/news/c...

Vaccines do not cause autism.

As with other coronaviruses, immunity to SARS-CoV-2 is short-lived. Prioritizing older persons for vaccination saves more lives, while targeting younger persons decreases the number of infections. Banning the vaccine will predictably result in more infections, hospitalizations and deaths from COVID.

If RFK Jr. had any interest in regulating big pharma or helping americans eat better or reducing chronic illness he would not have gutted the agencies he is in charge of. *Every* story about his alleged policy ideas should lead with this extremely elementary reality.

TL;DR: 5 justices say Trump doesn't have to immediately restore the funding, but 5 *also* signal that the underlying directives are unlawful. That sends a fairly strong (if mixed) message that Trump will lose these cases *eventually,* but only once they're brought in the Court of Federal Claims.

This is scant comfort to NIH-funded researchers. It would take many months or more than a year to re-file cases in Federal Claims Court, win them, and get grant money back. It's also expensive. Lawyers fees add up. The practical result is that all of this research is gone. What a waste.

Not just endangering US public health but global health www.thetimes.com/us/news-toda...

So glad to finally have this out with co-author @mallerybreban.bsky.social and very thankful for the many amazing people who contributed to this study and provided materials and input! 🦟🦠1/12 www.nature.com/articles/s41...

🧪 Senate appropriators say: NIH's budget gets a... boost! Rather than 40% cut, NIH gets a $400M *increase* in the Senate committee bill for FY26 (about +1%). "Congress has your back," said @murray.senate.gov. ADVOCACY MATTERS! There's still a long road (esp in the House), so keep up pressure.

📣The @aai.org allocated $8M RESTORE Grants Program, an initiative that will focus on providing financial support to researchers whose grants were abruptly terminated or frozen in 2025 for reasons unrelated to their scientific merit! 👏 Check the details 👇 #SupportResearch #Immunology

Wait, sometimes there are surprises. Apparently some Republicans have now grasped the immense damage to their communities caused by massive cuts to NIH funding. We told them this beforehand, yet they still thoroughly enjoyed seeing the massive cuts…until it affected them directly.

The assault on higher education is not just about coastal elite schools. "Federal agencies terminated or were attempting to terminate more than 4,000 grants across over 600 institutions. These grants are worth between $6.9 billion and $8.2 billion combined." www.insidehighered.com/news/faculty...

📜 A host organelle integrates stolen chloroplasts for animal photosynthesis 🧑‍🔬 Corey A.H. Allard, Amy S.Y. Lee, @nbellono.bsky.social, et al. 📔 @cellpress.bsky.social 🔗 www.cell.com/cell/abstrac... #️⃣ #PlantScience #Kleptosomes #Sacoglossan #SeaSlug #Photosynthesis

Not just Americans.....children around the world Cutting off support of the organization that has saved the lives of 17 million children around the world in the past 2 decades Front page @nytimes.com www.nytimes.com/2025/06/25/h...

This is a travesty & a nightmare. The US was a founder of @gavi.org. It lowers global vaccine costs, has vaccinated 1B children, & averted 19M deaths. This pull out will cost 100s of thousands of children's lives a year - and RFK Jr will be personally responsible. www.politico.com/news/2025/06...

Before the vaccine, close to 10% of measles infections resulted in deafness. It currently causes 100K children/yr to become blind. 1/1000 who recover completely will later develop a fatal encephalitis. Every infection disrupts the immune system, and can cause loss of all immunity to other infections

What happens when NIH is under threat? 📉 Fewer clinical trials. 💔 No new treatments for cancer, rare diseases. And long-term? We surrender our global leadership in biomedical research. NIHers risked everything to speak out, b/c the stakes are life and death. Stand with them here⬇️ zurl.co/OArEE

How innate immunity starts? Early embryos eliminate bacterial infections by epithelial phagocytosis, a conserved process from zebrafish to human embryos. Check our story: www.cell.com/cell-host-mi...

@bmoore-beth.bsky.social We are delighted to announce that Dr. Teresa O'Meara ‪was awarded the Henry Russel award at U-M. Our highest honor for an early-mid career faculty member for her outstanding research and teaching! @teresaomeara.bsky.social ‬ @umichmicroimmuno.bsky.social

I'm also excited to share some recent observations with @teresaomeara.bsky.social about how the growth phase of the emerging fungal pathogen Candida auris influences its pathogenesis: www.biorxiv.org/content/10.1...

I finally decided to be more active here after missing the science side of twitter. Please check out my paper, "IRE1α promotes phagosomal calcium flux to enhance macrophage fungicidal activity" with @drbadbug.bsky.social and @teresaomeara.bsky.social! www.cell.com/cell-reports...

Look at downtown LA right now

Our new work: ZIKV infection induces autophagy which mediates the downregulation of host entry factors TIM-1 and AXL. This, in turn, promotes sustained ZIKV infection by preventing superinfection and dampening the host innate immunity. www.pnas.org/doi/10.1073/...

Holy shit, New York! Here’s the full view. #NoKings #50501Movement

www.sciencedirect.com/science/arti... @drbadbug.bsky.social @teresaomeara.bsky.social Overall, our findings illustrate non-canonical IRE1α activation during infection and a function for IRE1α in supporting organelle contact sites to safeguard against rapidly growing microbes.