New landscape of the diagnosis of Alzheimer's disease www.thelancet.com/journals/lan... by @thelancet.com #Alzheimers #dementia #biomarkers #neuroscience #NeuroSkyence

Grateful for the opportunity to present my research at the UCC College of Medicine and Health Research Day, and honoured to have received a reward for my talk!! A huge thanks to the organizers for making this day possible 🌟 It’s always inspiring to see the incredible research being done @ucc.ie

*cracks knuckles* okay so you know how the media has a problem with taking snippets of scientific studies out of context and writing articles which mislead the public? now imagine a computer program is doing that when you ask it questions about scientific literature but also it makes stuff up.

⚛️🧪 folks--how do you keep your directories organized and uncluttered? I've got a billion papers I want to read/reference, too many project directories in a few different places (GH repos and stashes Documents folder), and old versions of other people's codes I need, which all needs reorganizing...

A key thing worth knowing about the AI super intelligence claims is that scientists who study cognition are clear we don’t even have a model of human intelligence, so how can you look at an AI and say it’s the same or better? We confuse lots of metaphors for cognition with knowing how it happens.

Altered Cholesterol Uptake by Neurons in Alzheimer’s Disease Linked to APOE4 Variant www.recercasantpau.cat/en/now/alter... by @irsantpau.bsky.social #Alzheimers #dementia #health #science #neuroscience

Interesting paper from the Goodman Lab: Identification of medication–microbiome interactions that affect gut infection www.nature.com/articles/s41...

4 pathways Mental health: Psychiatric conditions leading to cognitive decline Encephalopathy: Brain dysfunction conditions that escalate over time Mild cognitive impairment: Gradual cognitive decline progression Vascular disease: Cardiovascular conditions that contribute to dementia risk

Exciting Senior Scientist 👩‍🔬 👨‍🔬 role available in my research group 🧠 🦠 - Closing date Tuesday 5th August 2025. Please Share @apcmicrobiomeirel.bsky.social @anatneuroucc.bsky.social Full details here my.corehr.com/pls/uccrecru...

{tinytable} is a dead simple, ultra-flexible, and dependency-free #Rstats 📦 to turn data frames into beautiful tables: html, word, pdf, latex, typst, markdown, etc. v0.10.0 has cool new features and important bug fixes. Check out the detailed tutorials at: vincentarelbundock.github.io/tinytable/

Proud to share my new review from my MSCA-INSPIRE @inspiremsca.bsky.social "Host-microbiome relationship in depression: can human induced pluripotent stem cells play a role in unravelling mechanisms?" www.nature.com/articles/s41... @jfcryan.bsky.social @apcmicrobiomeirel.bsky.social @ucc.ie

p-tau217, the breakthrough blood biomarker for Alzheimer's, picks up risk the earliest and its performance surpasses all other tau biomarkers, across ancestries www.nature.com/articles/s43... My review erictopol.substack.com/p/the-breakt...

This is wild! Engineering E. coli bacteria to turn plastic waste into paracetamol (Tylenol) www.nature.com/articles/s41... www.nature.com/articles/s41...

Why do some people who have mutations of familial Alzheimer's not get the disease? They have protective genomic variants. A first-rate review @thelancetneuro.bsky.social thelancet.com/journals/lan...

Metformin boosts mitochondria and neurogenesis via AMPK/mTOR/SIRT3 in POLG mutant organoids https://www.biorxiv.org/content/10.1101/2025.06.08.658480v1

📣 Happy to share our review on host-microbiome genomics! We synthesize the growing field exploring interactions between human genetics and the microbiome, building a roadmap for mapping the dialogue between our genes and microbes Out now in Nature Reviews Genetics👇 www.nature.com/articles/s41...

We rely on deep sleep to clear the brain's metabolic waste products (that can induce inflammation), which decreases with aging. Now there's a discovery of a non-invasive way method to augment waste clearance in aged mice @nature.com www.nature.com/articles/s41...

The gutting of US biomedical research with loss of ~2,500 grants affecting research for cancer, Alzheimer’s, infectious disease, global health and much more www.nytimes.com/interactive/...

Inkscape plugin to rescale figures without distorting the text, and other useful features! github.com/burghoff/Sci...

The remarkable benefit of exercise was just extended to improved survival after cancer in a randomized trial @nejm.org nejm.org/doi/full/10....

There's a lot happening for predicting and preventing Alzheimer's disease. Here's the latest. erictopol.substack.com/p/predicting...

☕MedSky☕ In a study published in April in Nature Communications Biology, a team of researchers from Université de Montréal shed new light on how caffeine can modify sleep and influence the brain’s recovery, both physical and cognitive, overnight.

Social isolation with aging is linked with reduced healthspan and lifespan. A new study addresses why do we reduce social interactions as we age? journals.plos.org/plosone/arti...

New @nataging.nature.com Our body-wide pace of aging predicts healthspan and lifespan: outcomes of mortality, morbidity, cognitive impairment, and disability in US and UK cohorts www.nature.com/articles/s43...

Too much protein in the diet appears to carry a risk of atherosclerotic heart disease secondary to leucine's effect. An important report considering recent advocacy for very high-protein diets. @natmetabolism.nature.com nature.com/articles/s42...

"Protein may be hot, but it’s fiber that Americans need to eat a lot more of." "To get the full health benefits of fiber, it’s important to eat a variety of naturally fiber-rich foods and not rely on supplements...could actually lead to health problems..." gift link www.wsj.com/health/welln...

Unravel the Connection Between Depression, Exercise, and Gut Bacteria!🧠🏃‍♂️ Our study is investigating how exercise and gut health affect mental well-being. Follow the link tinyurl.com/Move4Mood or email [email protected] to register your interest! #ExerciseForMind #Move4Mood

#Medsky🧪 #IDsky #publichealth The benefits of Covid 💉 out weigh the risk & substantially reduced the risk of several more severe COVID associated cardiovascular outcomes, underscoring the protective benefits of complete vaccination. academic.oup.com/eurheartj/ar...

Grateful and proud to be among the 6 candidates on the ballot for joining the ALBA Network Board of Directors. 🗳️ Please vote and advance ALBA's actions for equity and diversity in neuroscience. Details: www.alba.network/elections @ucc.ie @apcmicrobiomeirel.bsky.social @researchireland.ie

Our ability to accurately predict #Alzheimer's disease years in advance of any symptoms keeps getting better with plasma proteins and A.I. analytics @nataging.nature.com www.nature.com/articles/s43...

🧠✨ We're launching the NSI-ECRN Monthly Microscopy Spotlight! Each month, we’ll feature a stunning image from an early career neuro researcher in Ireland. 📸 Want to be featured? Submit via our google form: lnkd.in/emzMH6s5 #NeuroTwitter #SciArt #PhDlife #Microscopy

So excited for this!! We have some great talks lined up 🤩 (no bias of course…!)

My conversation with Vijay Pande on promoting healthy aging app.magellan.ai/listen_links...

Congratulations to APC's David Clarke, Siobhain O'Mahony, Niall Hyland and Olivia O'Leary who were recently promoted to Professor at @ucc.ie

The science of aging is making rapid advances, such as molecular clocks, that are potentiating our ability to extend healthspan The latest Ground Truths with a NYT op-ed erictopol.substack.com/p/how-the-sc...

Understanding the development of bacterial colony: Physiology, new technology, and modeling -in Quantitative Biology onlinelibrary.wiley.com/doi/pdf/10.1...

Protein Homeostasis Impairment Alters Phenotypic Heterogeneity of Biofilm Communities #MolMicrobiol by Judith Matavacas and Claes von Wachenfeldt onlinelibrary.wiley.com/doi/10.1111/...

I spoke with @nfidvaccines.bsky.social's William Schaffner and Marla Dalton www.nfid.org/podcast/tech...

Excited to share our preprint on the South American MicroBiome Archive (saMBA)! 🌎🦠. We analysed one of the regions with the fewest microbiome samples but some of the highest biodiversities. 📄: shorturl.at/Lmvp5 🧵: What did we find—and why? Find out 👇 #microbiome #gut-microbiome (1/8)

When you can accurately predict risk of Alzheimer's from blood biomarkers (p-tau217) and do something about it. www.cnn.com/2025/04/07/h...

Our gut microbiome and its metabolites play a critical role for our glucose regulation, as does diet and exercise for improving it, through modulating the gut microbiome @naturemedicine.bsky.social www.nature.com/articles/s41...

We've greatly underestimated the role of the gut microbiome in fatty liver disease (MASLD). This open-access outstanding review @jclinical-invest.bsky.social is illuminating www.jci.org/articles/vie...

The World Health Organisation (WHO) has launched the ‘Integrated care for older people handbook: Guidance for person-centred assessment and pathways in primary care (ICOPE), 2nd edition’. Read More: buff.ly/gKbTHrw

Study finds strongest evidence yet that shingles vaccine helps cut dementia risk Older adults in Wales who had the jab were 20% less likely to be diagnosed with dementia that those not vaccinated www.theguardian.com/society/2025...

A new blood biomarker for Alzheimer's disease accurately tracks Tau protein aggregate build up in the brain www.nature.com/articles/s41... @naturemedicine.bsky.social

More data for why p-tau 217 is a breakthrough biomarker in healthy, cognitively intact people —Prediction; guiding clinical trials of new drugs www.nature.com/articles/s43... —Exercise reduces the level www.thelancet.com/journals/lan... jamanetwork.com/journals/jam...

Predicting the risk of developing Alzheimer's disease in the next 10 years with blood biomarkers, such as p-Tau217 www.nature.com/articles/s41... @naturemedicine.bsky.social

Harnessing microglia-based cell therapies for the treatment of neurodegenerative diseases www.sciencedirect.com/science/arti...

Of >105,000 participants with 30-year follow-up, only 9.3% achieved healthy aging (age 70, w/o any chronic diseases). Their diet was significantly associated with this outcome. @naturemedicine.bsky.social