Wie digitaler Hass und Ressentiment geschürt und geschützt werden, lässt sich hier exemplarisch sehen....wer noch nicht weiß, wohin zum Jahresende spenden: einfach an @hateaid.org www.sueddeutsche.de/politik/usa-...

Calling all archaeal enthusiasts! 🔬🔥 From molecular machines to microbial communities, Archaea never fail to surprise us! We are excited to announce the 2026 EMBO Workshop on the Molecular Biology of Archaea, 6–10 July in Cambridge, UK! Sign up here: meetings.embo.org/event/26-arc... #ArchaeaSky

Bacterial genomes encode a rich repertoire of antiphage systems, but we still know surprisingly little about when these systems are actually expressed. In this preprint, Lucas Paoli et al, ask what shapes antiphage systems expression in native contexts. www.biorxiv.org/content/10.6...

So true 🙈! And some of those changes are just not acceptable … changing the name of the ASGARD archaea superphylum? Not a good idea 😠!

Who invented non-reflective glass? American physicist & chemist Katharine Burr Blodgett in 1938. It revolutionized optics--& led to the coatings used today in everything from eyeglasses to phone screens. She was the first woman to earn a PhD in #physics from Cambridge, 1926. #WomenInSTEM #inventor

Uh, nice 🤩! One of our favourite archaea in stylish colours ☺️!

Delighted to share our latest preprint on reverse gyrase, a unique topoisomerase found exclusively in thermophiles! www.biorxiv.org/content/10.6...

A day of celebration @ the Grohmann Lab: since 10 years we are a fantastic team with lots of passion for science & teaching & #Archaea, #single-molecules and the many facets of #RNAbiology. I am endlessly grateful to all who are and were part of the lab and built a strong team - truly special 🫶!

Lol what is this.

Nice! Full attention to RNA polymerase - one of the most exciting molecular machineries (ok, ribosomes are cool too 😉)!

Dynamic protrusions mediate unique crawling motility in Asgard Archaea (Promethearchaeota) www.biorxiv.org/content/10.1... #jcampubs

The epitranscriptome formed by the growing number of modifications occurring within mRNA transcripts. We have been mapping mRNA modifications for over a decade. => Characterizing their functions -- especially on translation -- is a research frontier.

Big thank you to @katjapetzold.bsky.social for the invitation to the Chemical Mechanisms of Life Symposium in Uppsala … I love these kind of interdisciplinary symposia. Great place, great science, great people. And I got chocolate too! What a happy day ☺️!

🧬🛡️How are new immune mechanisms created? We show how Lamassu antiphage system, originated from a DNA-repair complex and evolved into a compact and modular immune machine, wt Dinshaw Patel lab in @pnas.org. 👏 @matthieu-haudiquet.bsky.social, Arpita Chakravarti & all authors! doi.org/10.1073/pnas...

An archaeal genetic code with all TAG codons as pyrrolysine www.science.org/doi/abs/10.1... #jcampubs

I like to show the evolution of this classification to the students to highlight the fantastic bioinformatics work of Kira and Eugene and co-authors but also to illustrate the rapid development in the field ☺️.

True!

Heute noch mal

Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️ Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...

How to become a "hot RNA" 🌡️? The answers were kindly provided by hyperthermophilic archaea: rRNA modifications are key! Check out this new publication presenting pan-modification profiling of the epitranscriptome. www.cell.com/cell/fulltex.... (1/3)

We are hiring…position suitable for PhD student with interest in ribosomes, antibiotics and cryoEM… www.uni-hamburg.de/en/stellenan...

ribosomologists take note 👇 archaeal ribosome hibernation factors aRDF, Dri, ...and now: Hib (see ALT) #Archaea #ArchaeaSky

Are you interested in Biomolecular Condensates and looking for a PhD training? Check out the 12 (!) open PhD positions (also 1 on smFRET & condensates 🙃) in Dresden @rtg3120.bsky.social @tudresden.bsky.social starting April 2026. Apply latest by 24 Oct 2025 here: dresdencondensates.org/join-us/

You can get MSAs directly from AlphaFold DB now (alphafold.ebi.ac.uk). I also missed the FoldSeek implementation, which lets you search for structurally similar proteins direktly. This saves some clicking around. Neat!

Thank you Jane Goodall for EVERY SINGLE SENTENCE in this interview to remind us of what is important and to encourage us to never loose hope and to try to make a difference everyday of our life 🤝🫶!!!

"Jane" (2017), directed by Brett Morgen, with music by Philip Glass, and based on unseen footage discovered shortly before, is one of the most enchanting films I've ever seen. Goodbye Jane Goodall, and thank you. www.youtube.com/watch?v=FRlU...

Our story describing the Panoptes bacterial immune defense system is now finally peer-reviewed and published today! www.nature.com/articles/s41...

Become my colleague @oxfordbiochemistry.bsky.social ! 2 Associate Professorships in the areas of - prokaryotic/eukaryotic microbiology - metabolism my.corehr.com/pls/uoxrecru...

Biogenesis and function of archaeal lipoproteins. This takes me back. The first papers I published from my new group were on lipoprotein biogenesis in Streptomyces with @proftracypalmer.bsky.social about 15y ago. www.nature.com/articles/s41...

Find up to date links to the Farnung lab's cloning, experiment designer, and buffer preparation software tools here: www.farnunglab.com/tools

Interested in removing particle-associated microbes from particles for eg flow cytometry, culturing, or other single-cell microbiology purposes? Led by graduating PhD stdnt Jordan Coelho: Detergent-based separation of microbes from marine particles journals.asm.org/doi/10.1128/... #jcampubs 🌊

To maintain genome integrity, extreme organisms like archaea rely heavily on repair pathways. This #FEMSmicroBlog explains how the halophile model organism Haloferax volcanii repairs DNA double strand breaks quickly and efficiently. #FascinatingMicrobes

new Lai lab #miRNA paper alert!! happy to share Renfu Shang's mechanistic insights into the mysteries of miRNA cluster assistance. wonderful collab with Niko Popitsch and @ameressl.bsky.social 🧵 later, but if you don't know this process, my daughter illustrated it.🧬 www.biorxiv.org/content/10.1...

Thank you for finding me here! I try to post new art every couple of days. My original works are temporary street art, but you can buy prints, books, calendars and postcards of their images at zinnart.com/store. Cheers!

Another great story from the Albers lab @archaellum.bsky.social 👍!! Congrats to all authors … exciting science ☺️!!! But how shall we name the motility structures now that archaellum is not exclusively reserved for Archaea any longer 😳??

Archaeal Virus Ph.D. project! (With Tessa Quax) www.rug.nl/about-ug/wor...

Looking for a new approach to studying or eliminating phages? Check out our study introducing anti-phage ASOs (antisense oligos) out in @Nature today. nature.com/articles/s4158…

What is single-molecule FRET? Watch @timcraggs.bsky.social explain how this technique measures nanometer-scale distances and captures single-molecule conformations - youtu.be/BpCsTVJkQyE #structuralbiology #moleculardynamics #discovery #smFRET

Please re-post: Interested in chromatin and its evolution? Good news! There's still time to join us in beautiful Catalonia (9-12 Dec) to discuss eukaryotic, bacterial, archaeal, and viral chromatin and how it all hangs together meetings.embo.org/event/24-evo... Abstract deadline: 30 September

Read more: argonautes.ngo/en/news/3rd-...

The Argonaute band rocked big time and indeed brought a lot of joy 🤩 ☺️! Thanks again guys!!

"m6A in the coding sequence: linking deposition, translation and decay" by Kathi Zarnack (@zarnack-group.bsky.social) & colleagues "This review explores [m6A in] mRNA decay, with a focus on the newly discovered CDS–m6A decay (CMD) pathway..." Read it here: authors.elsevier.com/sd/article/S...

Next stop: Cambridge for the Next Generation Biophysics Symposium ☺️. Seeing the „first generation DNA model“ combined with fantastic new biophysics at MRC LMB makes me joyful and happy 🙃.

#argonautes2025 day3 with amazing talks spanning widely over generegulation to evolution and parasitic interaction (via AGO). A presentation by the Argonautes Syndrom family alliance reminded how relevant research on Argonautes and related mechanisms is

🧬 Transcription elongation by RNA polymerase II relies on a web of elongation factors. Our new work shows how IWS1 acts as a modular scaffold to stabilize & stimulate elongation. Fantastic work by Della Syau! www.biorxiv.org/content/10.1...

Kicking off our third day of #argonautes2025 with a talk by Nobel Prize winner and all around amazing person, scientist, and mentor, Victor Ambros! 🐙

Conference season part II: one of my favourites, the Argonaute conference #Argonaute2025. As always with some specials: Ago playing cards ♠️♥️♣️♦️ & Ago gin (a favourite since the first meeting). Such fun to have co-organized this @svobodalab.bsky.social ❗️, @farmgirlphd.bsky.social & Gunter Meister.