With these authors you know it’s a must-read

Archaea , archaea everywhere ☺️!

Always a pleasure to work with the @archaellum.bsky.social lab - diving into the regulation of cell motility & shape in Haloferax this time. On our side, @felixgrunberger.bsky.social was the RNAseq guru again. Shoutout also to Anita Marchfelder (giving a posttranscriptional twist to the story).

Come and join us in beautiful Regensburg - we also have a job opening in Plant Biology

FoldMason is out now in @science.org. It generates accurate multiple structure alignments for thousands of protein structures in seconds. Great work by Cameron L. M. Gilchrist and @milot.bsky.social. 📄 www.science.org/doi/10.1126/... 🌐 search.foldseek.com/foldmason 💾 github.com/steineggerla...

Excited to share our latest preprint: "SWARM: A Single-Molecule Workflow for High-Precision Profiling of RNA Modifications" www.biorxiv.org/content/10.6... Led by Stefan Prodic #RNA #Epitranscriptomics #Nanopore 1/6

Just out @natrevimmunol.nature.com RNA-binding proteins and ribonucleoproteins as determinants of immunity www.nature.com/articles/s41... gives our perspective on this growing area of research. Special thanks to the editor Alexandra, for streamlining the manuscript.

Important point by @evgenii-protasov.bsky.social ! Same applies for the recent taxonomic changes in the archaeal domain of life.

SAVE THE DATE! The next instalment of the long-running Bacterial and Archaeal Cell Division Conference will take place at www.marriott.com/en-us/hotels..., Italy from the 20th to 23rd of April 2027. Organisers: me, @s-lab.bsky.social, @awehenkel.bsky.social. More info soon. #MicroSky

I am a big admirer of Joan Steitz and her amazing work! Admirable scientist indeed!

Let’s get this started and on an RNA high 😅

Such a thoughtful and thought-provoking article. Excellent Sunday read. Especially today. Explore this gift article from The New York Times. You can read it for free without a subscription. www.nytimes.com/2026/01/25/o...

new paper from the Lai lab! Renfu Shang performs careful mechanistic dissection of miRNA cluster assistance and reveals many insights and surprises to this enigmatic regulatory strategy that gives suboptimal miRNAs a boost. if you love Northerns, you'll ♥️ this! 🧬 genesdev.cshlp.org/content/earl...

Our latest CRISPR ring nuclease paper focusses on Csx15 - which seems to act as of a sponge as well as a canonical phosphodiesterase. Great work led by @haotianchi.bsky.social www.biorxiv.org/content/10.6...

🌟 2026 Nucleic Acids Research Database issue 🧬 182 papers, 84 new databases, plus Breakthrough Articles on JoGo (global long‑read haplotypes) and So3D (3D spatial genomics). Browse the issue and Editorial: academic.oup.com/nar/issue/54... academic.oup.com/nar/article/... @danielrigden.bsky.social

#ECR save the dates! 🗓️ In der Reihe #PROSPECTS informiert unser Team #Karriereförderung auch 2026 regelmäßig über die Fördermöglichkeiten bei der DFG. Hier haben wir die Infotalks für die erste Jahreshälfte. Teilnahme ohne vorherige Registrierung möglich, Link erscheint hier. 👉 sohub.io/bvv0

I am very pleased to share that our database of prokaryotic and viral histones, ProHistoneDB, is now available online at prohistonedb.org. Please also see the accompanying article in J Mol Biol: doi.org/10.1016/j.jm...

Dominant contribution of Asgard archaea to eukaryogenesis www.nature.com/articles/s41...

Pleased to announce that I've joined the editorial board of the Biochemical Journal portlandpress.com/biochemj as an associate editor. I'd love to receive manuscripts focussed on CRISPR, anti-viral defence, archaean biochemistry and nucleic acid processing enzymes. @biochemsoc.bsky.social

Guided tour through the small protein landscape of Methanosarcina mazei using proteomics and biochemical approaches #microbiology #methanogens #methane @femsjournals.bsky.social @femsmicro.org doi.org/10.1093/fems...

The @zeitlingerlab.bsky.social is pleased to announce @sergio-gma91.bsky.social’s preprint “High-resolution binding data of TFIID and cofactors show promoter-specific differences in vivo” (www.biorxiv.org/content/10.6...). TLDR; TFIID behaves differently depending on promoter type. More below:

🚨We are looking for a coordinator located at @uni-wuerzburg.de for our new excellence cluster NUCLEATE - Cluster of Nucleic Acid Sciences and Technologies 👇 www.uni-wuerzburg.de/fileadmin/03... Deadline: Jan 31 st, 2026

Deep-learning dive into the antimicrobial potential of Archaea

Amazing work showing how TDMD plays out on the molecular level! Congrats!!

Slightly overdue article highlight! In PNAS, we use smFRET to reveal how polypeptide release factor 2 (RF2) undergoes a cascade of structural changes to catalyze polypeptide release during translation termination and ArfA-mediated ribosome rescue. 🧵⬇️ doi.org/10.1073/pnas...

A new year brings new opportunities: we are looking to fill a permanent professorship position with a Microbiologist preferably with expertise on archaeal biology, RNA biology or imaging techniques to unravel cell biology in prokaryotes! Please share and/or apply :)! www.nature.com/naturecareer...

A (belated!) highlight from an excellent collaboration with @dunhamlab.bsky.social and #HouLabTJU. In this Nat Commun paper, we combine smFRET and cryo-EM to show how the tRNA modification m¹G37 stabilizes the reading frame—and what happens when it’s missing.

The Human Archaeome: Commensals, Opportunists, or Emerging Pathogens? #microbiology #archaea #GutMicrobiota #MicroSky #ArchaeaSky www.mdpi.com/2076-0817/14...

jede*r kann etwas tun

Wie recht @meta-bene.bsky.social doch hatte:

Troubleshooting common errors in assemblies of long-read metagenomes www.nature.com/articles/s41... #jcampubs

Marine archaea and their functional networks in oceanic biogeochemical cycling link.springer.com/article/10.1...

The final edition of our “New Microbes Discovered in 2025” series is here. After exploring new viruses, bacteria, and fungi, this last #FEMSmicroBlog highlights the archaea identified in 2025: buff.ly/pJpA0Ax #NewMicrobes

Thanks to all who provide these illustrations for free - it helps so much for teaching etc! It’s like a Christmas present again and again ☺️

A free, open-access library of high-quality organism illustrations for science communication

Wie digitaler Hass und Ressentiment geschürt und geschützt werden, lässt sich hier exemplarisch sehen....wer noch nicht weiß, wohin zum Jahresende spenden: einfach an @hateaid.org www.sueddeutsche.de/politik/usa-...

Calling all archaeal enthusiasts! 🔬🔥 From molecular machines to microbial communities, Archaea never fail to surprise us! We are excited to announce the 2026 EMBO Workshop on the Molecular Biology of Archaea, 6–10 July in Cambridge, UK! Sign up here: meetings.embo.org/event/26-arc... #ArchaeaSky

Bacterial genomes encode a rich repertoire of antiphage systems, but we still know surprisingly little about when these systems are actually expressed. In this preprint, Lucas Paoli et al, ask what shapes antiphage systems expression in native contexts. www.biorxiv.org/content/10.6...

So true 🙈! And some of those changes are just not acceptable … changing the name of the ASGARD archaea superphylum? Not a good idea 😠!

Who invented non-reflective glass? American physicist & chemist Katharine Burr Blodgett in 1938. It revolutionized optics--& led to the coatings used today in everything from eyeglasses to phone screens. She was the first woman to earn a PhD in #physics from Cambridge, 1926. #WomenInSTEM #inventor

Uh, nice 🤩! One of our favourite archaea in stylish colours ☺️!

Delighted to share our latest preprint on reverse gyrase, a unique topoisomerase found exclusively in thermophiles! www.biorxiv.org/content/10.6...

A day of celebration @ the Grohmann Lab: since 10 years we are a fantastic team with lots of passion for science & teaching & #Archaea, #single-molecules and the many facets of #RNAbiology. I am endlessly grateful to all who are and were part of the lab and built a strong team - truly special 🫶!

Lol what is this.

Nice! Full attention to RNA polymerase - one of the most exciting molecular machineries (ok, ribosomes are cool too 😉)!

Dynamic protrusions mediate unique crawling motility in Asgard Archaea (Promethearchaeota) www.biorxiv.org/content/10.1... #jcampubs

The epitranscriptome formed by the growing number of modifications occurring within mRNA transcripts. We have been mapping mRNA modifications for over a decade. => Characterizing their functions -- especially on translation -- is a research frontier.

Big thank you to @katjapetzold.bsky.social for the invitation to the Chemical Mechanisms of Life Symposium in Uppsala … I love these kind of interdisciplinary symposia. Great place, great science, great people. And I got chocolate too! What a happy day ☺️!

🧬🛡️How are new immune mechanisms created? We show how Lamassu antiphage system, originated from a DNA-repair complex and evolved into a compact and modular immune machine, wt Dinshaw Patel lab in @pnas.org. 👏 @matthieu-haudiquet.bsky.social, Arpita Chakravarti & all authors! doi.org/10.1073/pnas...