Dichotomization is only one of the issues leading to the vicious circle of #ResearchWaste. Many reasons, one I'm finding deeply troubling, being the suboptimal (oh, I'm polite), suboptimal (quantity & quality) education in biostats & research methods in med schools. #MedEd has serious catch up to do

The stupidity, the criminal vandalism, the wanton destruction of information involved in dichotomisation statmodeling.stat.columbia.edu/2026/02/14/t...

If you missed my talk on Tuesday, you can now watch the video!👇🏼

Creatine & Cancer 'risk'😅 in NHANES: Food measured post cc Dx, survivors, reverse causation, residual confounding, overadjustment, collider bias, sparse upper tail data, model driven shape. Smooth looking noise. Yay for a great case study to show my students🚀🥳 www.frontiersin.org/journals/nut...

Disease surveillance capacity is very useful, particularly when integrated with decision making by design. We should build even more. www.bmj.com/content/392/...

New systemwide analysis shows trends in lipoprotein(a) testing are evolving and may significantly influence clinical decision-making and cardiovascular risk management. https://ow.ly/5nL150XZTaL #Lp(a) #CardiovascularCare #ClinicalPractice #CardioSky #MedSky

In the meantime, people who are specifically trained to provide evidence-based patient counseling services, are rarely incorporated into the proverbial 'multidisciplinary teams'. Because the 'system' is not built for that.

While authors use careful language, aficionados r already rejoicing. Massive threats to causal inference, res. confounding, colliders, etc...., most in direction of overestimation.To separate signal from noise we need serious causal thinking-driven research & edu. link.springer.com/article/10.1...

New PubPeer comments: @ioanaacristea.bsky.social on the post-hoc study registry = violation of the Helsinki declaration) @ianhussey.mmmdata.io with a full table of effect sizes (many impossibly large, d > 7) me just about the large SMD of the main result and what this means (shit vs. chocolate)

Abstract deadline extended to Jan 12. Everyone enjoying holidays will appreciate this :-) The Art and Science of SDM is the way to go for genuine patient-centered care and true personalized medicine. So much to learn. So much to translate to practice.

IFM in its best form is practicing off rodent studies &underpowered trials measuring non-validated surrogate risk factors. It centers provider enthusiasm abt their favorite mechanism & high risk of bias data over providing real patient centered care that communicatess honestly what we know/dont

We know the drivers of research waste in academia are ⚠️Pressure to maximize papers and PhD students ⚠️Endless demands on time due to poor management ⚠️Stakeholders don't insist on robust quality systems to underpin mission critical work Solutions that don't address these are pointless.

I chatted with Evan McLoughlin on The Giant's Shoulder podcast about the flaws that undermine claims of a link between autism and the microbiome cc @statsepi.bsky.social @deevybee.bsky.social www.youtube.com/watch?v=ie0S...

We did a thing. 😬

Europe's larges research info search engine/discovery platform LIVIVO, operated by the German National Library of Medicine, ZB-MED: now indexing preprints. Great filters and search functions. This alternative to PubMed is growing bold & fast 😍

A letter from myself and @jdwilko.bsky.social that expands on this a bit more. Thanks to Fertility and Sterility for the opportunity. doi.org/10.1016/j.fe...

i have this easy to use surgery cheatsheet for all you stats peeps who're missing out:

Eliminating barriers to #mentalhealth care for physicians is essential to prevent untreated conditions and suicides, improve well-being, and maintain high-quality patient care. ja.ma/4mH9myk

The 🆕 AHA/ACC/Multisociety #ClinicalGuideline on high blood pressure provides updated recommendations for clinicians on the prevention, detection, evaluation, and management of high blood pressure in adults. Get the details ➡️ https://bit.ly/47xv5o7 #Hypertension #JACC #CardioSky #MedSky

📌 The SPIRIT 2025 statement updates the guidelines for randomized trial protocols to enhance their completeness, transparency, and consistency, benefiting stakeholders involved in clinical research. ja.ma/4fzMVZS

View the DCI Network Conference Patient-Powered Progress: Revolutionary Digital Strategies for Optimal Patient Engagement and Healthcare Delivery Wednesday, June 25-27, 2025 | Harvard University Recordings: www.dcinetwork.org/collection/c... View Highlights at www.linkedin.com/pulse/view-r...

🆕 New in AJPC: High-Density Lipoproteins, Part 1 Explore HDL's role in CVD prevention—epidemiology, antiatherogenic effects & therapies to raise serum levels. 🔗 www.sciencedirect.com/science/arti... #HDL #Cardiology #LipidHealth #AJPC #PreventiveCardiology

Do beta blockers still belong among the contemporary therapies for ischemic heart disease? The latest episode of the Beyond Journal Club podcast from @coreimpodcast.bsky.social and NEJM Group explores the REDUCE-AMI trial. Full episode: nej.md/4ekdlxX  #MedSky #CardioSky

“We pay experts to examine important and influential scientific publications for errors ... We expect most published research to contain some errors ... our reward system pays bonuses to both authors and reviewers even when minor errors are found ..." statmodeling.stat.columbia.edu/2025/07/13/e...

We recently published a preprint with the protocol & pilot data from 𝐀𝐭𝐡𝐞𝐫𝐎𝐌𝐈𝐂𝐒. AtherOMICS is a biobanking project built in our lab over the past 3 years aiming to provide access to multi-omics/multi-modal data from human atherosclerotic tissue❗ Some innovations of AtherOMICS👇

www.sciencedirect.com/science/arti... Medicalisation of public health: a narrative review Yep This stuff matters enormously The medicalization of population health policy is a significant risk to, well, health Read alongside Lantz pubmed.ncbi.nlm.nih.gov/37096631/

🔵 European #PublicHealth on BlueSky, including: 🔵 EuroHealthNet @eurohealthnet.bsky.social 🔵 European Public Health Association @eupha.bsky.social 🔵 European Health Forum @gasteinforum.bsky.social 🔵 European Observatory on Health Systems & Policies @obshealth.bsky.social go.bsky.app/K2JB6CN

The 2025 KER Unit’s Care that Fits conference is outside US for 1st time. See you in Paris Oct 7-10, 2025. Register here ce.mayo.edu/ctf2025 See you all - researchers, clinicians, patients, care activists!!! For info re KER Unit and prior Care that Fits conferences visit carethatfits.org

We need a sustainable and independent medical literature repository. @zbmed.bsky.social ‬ embarked on this mission. Timely, thoughtful, forward-looking. @hildabast.bsky.social describes it here absolutelymaybe.plos.org/2025/05/14/g...

ZB MED invites you! 🧬 We’re planning an open, reliable alternative to PubMed – and want to share our vision. 📅 12 June | 5pm CEST | Online Let’s talk about resilient life sciences infrastructure in Europe. Info + sign up: eveeno.com/informati... #OpenScience #LifeSciences

Poorly worded questions in nutrition will never die because they facilitate people talking past one another. When your question violates all the first principles of nutrition science, it will never get answered

The stethoscope is now an app. Developed by a ingenious 14-yr old teen, tinkering with AI. There are good news in the world. www.smithsonianmag.com/innovation/t...

Pairing this w/ #LifestyleMedicine and all things Prevention :--) Invite your neighbors over Eat in moderation Drink tea Keep it simple Smile

As scientists it is difficult to stay in love with the questions once you fall in love with the answers

Feel this pain. statsepi.substack.com/p/the-review...

As grant money starts drying up, it's more important than ever not to waste it on paying publishers' open access "article processing fees" when we can host PDFs for free. Tom Morgan and I wrote a paper on this, forthcoming at Science and Public Policy. Accepted draft here: osf.io/preprints/os...

📢Call for Submissions! #CircOutcomes Special Issue on Cardiovascular Epidemiology: From Findings to Impact ⏰Submit by: August 15 🔗Learn More: ahajournals.org/circoutcomes... #AHAJournals #Cardiosky

Germany's central medical library, ZBMed, is building an alternative to PubMed. It will be open source, based on MeSH & associated data standards, built to be sustainable in case PubMed becomes unreliable - with APIs & MeSH maintenance. Open meeting called! 1/2 www.heise.de/news/Wegen-T... #MedLibs

WHI gone, DPP gone. Landmarks in chronic disease epidemiology, which informed and inspired. What are they going to be replaced with? What is the vision going forward?

To protect our mental health, we all need a break from doomscrolling, but what should we do instead? In my new Psychology Today piece I share the science behind how creative pursuits quiet the noise of stress and can even help with depression. www.psychologytoday.com/us/blog/shri...

Profit motives absolutely generate a great deal of societal value. However, the societal value of a university is completely rooted in the fact that they *aren't* profit driven. This is what allows universities to pursue new knowledge for the public good....

Excellent tool for RCT enrollment- patients in the EU can locate an 'RCT near me'.

Headline: Drinking green tea can CUT YOUR RISK OF DEMENTIA. Study: Japanese people who drink at least 600ml (~3-5 cups) of green tea a day have 1.5% fewer brain lesions than people who drink little/no green tea. Study funded by Suntory beverages.

Thrilled to share our state of art review led by extraordinary @sophieclaudel.bsky.social “Albuminuria in Cardiovascular, Kidney, and Metabolic Disorders: A State-of-the-Art Review" www.ahajournals.org/eprint/SXXGK... @ahascience.bsky.social @ahajournals.bsky.social @asnkidney.bsky.social

Timely for #IWD2025 is the investigation of #stress due to #caregiving & development of #hypertension in younger Black women: The Jackson Heart Study Dr Milla Arabadjian ahajrnls.org/3XulyIz

Pilot & feasibility studies are important for 1) design of future, larger studies, 2) translation of research to practice. Yet, so often, they do not get the recognition/admin support, funding support they deserve. They are also the first steps for budding clinical researchers. Great read--->

More hits to #NIH: "The Trump administration has imposed a new restriction on employment that could push out thousands of NIH’s senior scientists: The agency cannot retain scientists in 1-year to 4-year positions that have long been routinely renewed." 🧪 @jocelynkaiser.bsky.social at @science.org