New publication in @insight.jci.org! 🎉 We uncover a key role for #Nectin-4 in #PancreaticCancer, opening the door to new therapeutic strategies. Read the full paper here: insight.jci.org/articles/vie... Stay tuned — our multicenter phase II clinical trial #NEC4NEOP is coming next year! 🔬✨

Excited to share our new publication in OncoImmunology! 🎉 We explore the association of intratumoral regulatory T cells with treatment response to neoadjuvant chemotherapy and prognosis in #GastroesophagealAdenocarcinoma. Read the full paper here: doi.org/10.1080/2162...

The Department of Visceral, Thoracic, and Vascular Surgery at the Carl Gustav Carus University Hospital is hosting a #WorldPancreaticCancerDay Symposium: 📅 Thursday 20 Nov | 5:00 - 8:00pm 📍 Albertinum ℹ️ Open to everyone with an interest in pancreatic cancer: weltpankreaskrebstag.de/veranstaltun...

Excited to announce a new publication from the @seifertlab.bsky.social identifying soluble TIM-3 and Galectin-9 as novel biomarkers in #GastricCancer and #GastroesophagealAdenocarcinoma. Out today in @cp-iscience.bsky.social: www.cell.com/iscience/ful...

Congratulations to Dr. David Digomann, research fellow in the @seifertlab.bsky.social , on receiving the AIO scholarship for #ESMO25. David will also present his latest work, showcasing a novel biomarker for #GastricCancer in a poster presentation - soon to be published.

Please join us at the Dresden Immunology Seminar Series

Celebrating the 10-year anniversary of the Seifert Lab at University Hospital Dresden and NCT Dresden with a fantastic lab retreat. Grateful for this remarkable team!

Join us at #GI26 to learn about the latest diagnostic and therapeutic strategies in GI cancers to transform your patient outcomes in a program planned by and featuring multidisciplinary experts. Register today: brnw.ch/21wV49s

#Cancer does not develop overnight. Researchers at the DKFZ have now developed a method that allows for the first time to reconstruct the evolution of cancerous cells from a single tissue sample. t1p.de/1jfo4

Are you looking to start your #lab in a fantastic scientific 🧪environment, with great colleagues, and in a spectacular place to live? Then check out our open #junior #faculty position at the Department of Oncology, University of Lausanne, Switzerland: www.unil.ch/dof/en/home/... ⏰ Deadline 27 June

www.aacr.org/meeting/aacr... Abstracts and award applications are due July 15. See you in Boston Sep 28 to Oct 1. @theaacr.bsky.social #PancreaticCancer #2025

MATTERHORN manuscript published today in the New England Journal of Medicine. #ASCO25 www.nejm.org/doi/full/10....

More news from #ASCO25 Plenary! MATTERHORN results: Perioperative durvalumab/FLOT shows superior EFS over placebo/FLOT in early-stage, resectable G/GEJ cancer: brnw.ch/21wT4R8 #ASCODailyNews #GICSM

Submit your abstract to #CICON25 in #Utrecht and present your research as poster or short talk: cancerimmunotherapyconference.org

#MedNews - First-line treatment with #anlotinib plus #penpulimab significantly improves the outcomes of patients with unresectable hepatocellular carcinoma relative to #sorafenib. Full story 👉 buff.ly/aA3W8IV #OncSky #HCC

🚨 FOLFIRINOX vs. GEM Nab Paclitaxel for LAPC @ascocancer.bsky.social 💉 171 pts median PFS 9 months better in FOLFIRINOX group 🎯 FOLFIRINOX improves PFS significantly compared with gemcitabine and is well tolerated in LAPC ascopubs.org/doi/10.1200/...

Pancreatic cancer, often linked to smoking, obesity and diabetes, is predicted to become the 2nd leading cause of cancer-related death by 2030. A recent Seminar discusses the need for novel therapies & future directions for research: tinyurl.com/ywue2nfs

Do you want to do your #postdoc in #cancerresearch with the most prestigious #fellowship in Europe? Apply to DKFZ Marie Skłodowska Curie MasterClasses by May 19. Projects in #cellandmolecularbiology #genomics #bioinformatics #immunology #medicaltechnology, #epidemiology. Apply here: t1p.de/nx6tu

🚨New publication! 🚨 A new method for evaluating CA19-9 during neoadjuvant therapy, and its role in predicting overall and disease-free survival in BR-PC. A way towards personalised prognostication! 💜💪🏻🙏🏼 doi.org/10.1097/SLA....

Neoadjuvant chemo 🤜🤛 surgery for Resectable PDAC 🇯🇵 RCT 💉 Gemcitabine + S1 median OS 37 months vs. 26 💡 Is neoadjuvant chemo extending survival over upfront surgery?! 🤔 What are your thoughts?! 💭 journals.lww.com/annalsofsurg... #HPBSky #Surgsky

📌 Save the date: The next German #Cancer #Congress will take place from February 18 - 21, 2026. The website is now online: www.deutscher-krebskongress.de/english 200 #scholarships are available for students & certain professionals! All information can be found at: t1p.de/hi414 #DKK2026 #MedSky

Now online in Cancer Discovery: Cytosolic Phospholipase A2 Determines Intercellular Heterogeneity of Stress Granules and Chemotherapy Response - by Alexandra Redding, Elda Grabocka, and colleagues doi.org/10.1158/2159...

Congrats to Yelena Janjigian and team on their study in @naturemedicine.bsky.social, which presented biomarker analysis of nivolumab plus chemotherapy or ipilimumab in #gastroesophagealcancer. @mskcancercenter.bsky.social www.nature.com/articles/s41...

Single-cell multi-stage spatial evolutional map of esophageal carcinogenesis

👏 Congrats to Sarah Cronjaeger @seifertlab.bsky.social on receiving the Werner-Creutzfeldt-Stipend from #DeutscherPankreasclub. Sarah is investigating a novel therapeutic approach for #PancreaticCancer. Our multicenter NEC4NEOP trial will start to recruit this year.

Just announced! Seven new Cancer Grand Challenges – with awards of up to £20m – available for research teams around the world to tackle the biggest questions in cancer research. Read more: cruk.ink/4ha3LgZ 1/2

Great work from the VinodBalachandranLab! Vaccine targeting #PancreaticCancer shows promise in new study of clinical trial: www.cbsnews.com/news/pancrea...

🔥 Nature paper: RNA neoantigen vaccines prime long-lived CD8+T cells in pancreatic cancer www.nature.com/articles/s41...

Do T cells predict postoperative complications in #PancreaticCancer surgery? Check out our most recent paper: journals.lww.com/aosopen/full...

British Journal of Cancer Paper: Extracellular vesicles from pancreatic cancer and its tumour microenvironment promote increased Schwann cell migration www.nature.com/articles/s41...

Adjuvant Chemotherapy After Resection of Localized Pancreatic Adenocarcinoma Following Preoperative FOLFIRINOX jamanetwork.com/journals/jam...

Nature research paper: IL-33-activated ILC2s induce tertiary lymphoid structures in pancreatic cancer https://go.nature.com/4alg8Vz

Perioperative therapy for #Pancreas Cancer ⭐️ A stellar lecture by the great Matthew H Katz 🇺🇸 @mdanderson.bsky.social ⭐️ All you need to know, and future perspectives in the eyes of a true pioneer of neoadjuvant chemo #HPBSky #SurgSky #MedSky youtube.com/watch?v=kIlH...

💫New Article Ongoing replication stress pathways and T cell clonal responses differentiate liver and lung recurrence and are associated with different clinical outcomes in PDAC. ✏️by Jason Link & Rosalie Sears and team www.nature.com/articles/s43...

Registration and abstract submission for the 22nd CIMT Annual Meeting are now open! Submit your abstract and present your research at #Europe'sCancerImmunotherapyMeeting in Mainz, Germany, May 12-14, 2025. www.meeting.cimt.eu

@ucsdmedschool.bsky.social researchers have identified a key enzyme that promotes the growth and spread of the most common form of pancreatic cancer. @CR_AACR today.ucsd.edu/story/enzyme...

2️⃣0️⃣2️⃣4️⃣ Pancreas Wrapped🎄 🔟 October 🔥 Clinical and Financial Validation of the ISPGS definition of PPAP 🌍 Prospective International study on 3000 PD 🧪 POH 24% ⚡️ PPAP 7% 🏥 PPAP grading influence LOS, ICU, readmissions, costs journals.lww.com/annalsofsurg...

2️⃣0️⃣2️⃣4️⃣ Pancreas Wrapped 🎄 9️⃣ September 😱 Pancreatic Cysts on the @nejm.org !!! 🍇 A comprehensive review of a NOT rare disease … 🚀 It’s time to increase the evidence and ameliorate patients’ treatments www.nejm.org/doi/full/10.... #HPBSky #PancreasSky

2️⃣0️⃣2️⃣4️⃣ Pancreas Wrapped🎄 8️⃣ August @bjsopen.bsky.social Surgery for non functioning pancreatic neuroendocrine tumors 🍇 Are we harming our patients !? 🤔 🔎 Almost 400 resected P-NET with path and FU analysis 4⃣0⃣% Inadequate treatment (34% potential overtreatment) academic.oup.com/bjsopen/arti...

2️⃣0️⃣2️⃣4️⃣ Pancreas Wrapped 🎄 7️⃣ July 🇯🇵 Mastering the dissection of the first jejunal branches during pancreatoduodenctomy 🏣 Japanese surgeons secret weapon: sketching the anatomy of each case before surgery! 🥷 🫵 How do you preop plan your surgery?! #HPBSky #SurgSky #PancreasSky

2️⃣0️⃣2️⃣4️⃣ Pancreas Wrapped 🎄 6️⃣ June 🍇 How to prevent IPMN progression to cancer?! 🫸 🚬 Quit smoking is THE answer! Smoke correlates with HGD and invasive cancer 🚨 www.dldjournalonline.com/article/S159... #HPBSky #PancreasSky #SurgSky

2️⃣0️⃣2️⃣4️⃣ Pancreas Wrapped 🎄 5️⃣ May: Left side pancreatectomy 🙊 do we speak the same language?! 🌍 International Delphi consensus 4️⃣ resection categories based on anatomy + additional procedures / technique 🔪🤖 👉 Distal is not just “distal” in @bjsurgery.bsky.social academic.oup.com/bjs/article-...

Happy Holidays from the @seifertlab.bsky.social!🎄

2️⃣0️⃣2️⃣4️⃣ Pancreas Wrapped!🎄 4️⃣ April 🍇 When to STOP surveillance for IPMN?! 👴🏻 Age 75 and CACI > 3 predict malignancy BUT ... death for any cause is 15% 😱 👗 Tailored approach needed! (and what does "surgically fit mean?"...) Read it on GUT @bmj.com #HPBSky #PancreasSky gut.bmj.com/content/73/8...

2️⃣0️⃣2️⃣4️⃣ Pancreas Wrapped!🎄 3️⃣ March The Pandorina RCT on @thelancet.bsky.social Do you drain 💦 a distal pancreatectomy?! 🧐 🚨 Practice changing RCT 🇳🇱 🇮🇹 282 pts ✋ NO drain better outcomes! ⬇️ POPF 12% vs. 27% 👉Drainless DP new standard! 👈 www.sciencedirect.com/science/arti...

2️⃣0️⃣2️⃣4️⃣ Pancreas Wrapped 🎄 2️⃣ February : the EUROPA RCT 🇩🇪 Robotic 🤜🤛 open PD @thelancet.bsky.social 🥇 Primary endpoint CCI no difference 🟰 90 days mortality 4.8 % 🟰 blood loss 🤖 Higher complications (60% vs. 30%) and DGE 🙅‍♂️ Conversion rate 23% 🫵 Comments?! #HPBSky thelancet.com/pdfs/journals/…

2⃣0⃣2⃣4⃣ Wrapped Pancreas! 🎄 1⃣ January The NORPACT-1 trial released on @thelancet.bsky.social Gastroenterology and Hepatology Neoadjuvant FOLFIRINOX 🤜🤛 Upfront surgery for resectable pancreatic cancer 🫵 What is your practice now !? 🫵 www.thelancet.com/journals/lan... #HPBSky #PancreasSky

Tremendous resource paper from NCI-PSRC member Nina Steele on collating a single cell RNA SEQ dataset in #PancreaticCancer The dataset is now housed with the PSRC. aacrjournals.org/clincancerre...

Join us today for World Pancreatic Cancer Day #WPCD2024. We are dedicated to fight #PancreaticCancer. We need more attention, awareness, and progress to help patients fight and survive this disease.