1/3: What happens in the #brain when moving your eyes? Using closed-loop #EyeTracking with simultaneous intracranial #EEG in humans, we found that: *Saccades boost visual responses but reduce network connectivity. *Excitability changes and visual features are coded along the saccade–fixation cycle.

👁️🧠 New preprint: We demonstrate the first data-driven neural control framework for a visual cortical implant in a blind human! TL;DR Deep learning lets us synthesize efficient stimulation patterns that reliably evoke percepts, outperforming conventional calibration. www.biorxiv.org/content/10.1...

Really excited that our special collection generated from the last CPPC conference is in the Journal of Neuroscience. Check out this article for a preview of all the great work featured. w/ @erinlrich.bsky.social @narayananlab.bsky.social and Jeremy Seamans www.jneurosci.org/content/45/3...

🚨New preprint alert🚨 We used closed-loop optogenetics to causally test the importance of inhibitory spike timing in network function and found that manipulating PV+ cell theta phase locking in the dentate gyrus can shift seizure susceptibility (both ways!)

New preprint from the lab! 🧠 Led by Juliana Trach, w/ Sophia Ou Using fMRI, we discovered evidence for time-sensitive reward prediction errors (RPEs) in the human cerebellum. Builds on, and extends, recent work in both rodents and NHPs

Here’s some high desert happiness for your TL:

Check out @tifenpan.bsky.social 's just published paper! we demonstrate how to use RNNs to infer latent variables from cognitive models, even when standard methods don't work easily.

Thrilled to see our TinyRNN paper in @nature! We show how tiny RNNs predict choices of individual subjects accurately while staying fully interpretable. This approach can transform how we model cognitive processes in both healthy and disordered decisions. doi.org/10.1038/s415...

🚨We believe this is a major step forward in how we study hippocampus function in healthy humans. Using novel behavioral tasks, fMRI, RL & RNN modeling, and transcranial ultrasound stimulation (TUS), we demonstrate the causal role of hippocampus in relational structure learning.

“One way to fight a profit-driven system that treats people as disposable is to instead treat people as redeemable. Solidarity means not writing anyone off completely, not throwing anyone away. It holds out hope that systems & individuals can change." Officially out in paperback as of yesterday.

while I'm disappointed to not receive the @onemindorg.bsky.social rising star award again, I'm grateful that I don't have to listen to Train at their music festival... 😂 Congrats to the awardees!

Here’s some high alpine happiness (type II) for your TL

Delighted to share our work on replay and successor representations! We find replay during very short task pauses in human visual cortex that is linked to learning SRs & happens when learning is implicit. Study led by @lnnrtwttkhn.bsky.social #compneuro #neuroskyence www.pnas.org/doi/10.1073/...

May this portion of the dissent by Ketanji Brown Jackson haunt John Roberts forever and be the final word on his tenure as Chief Justice.

I've updated my literature review of studies of aperiodic neural activity in clinical disorders, adding ~30 papers, taking it to 177 reports across 38 disorders! It's got a review of results so far, discussion of themes & issues, & recommendations for future work! www.medrxiv.org/content/10.1...

Here's a revised preprint out of our lab detailing human neuron responses to theta burst MACROstimulation. Probably will be the version of record; who knows. eLife says it's "important" and "convincing." Who even needs an impact factor with that sort of testimonial! doi.org/10.7554/eLif...

Datasets like NSD & THINGS offer rich stimuli but often test a single task. After great conversations at #CCN2025 on multi-task studies & generalization in brains & models, I thought I would repost our perspective for those interested in this topic. We need multiple tasks!👉 doi.org/10.1038/s415...

CCN has been fantastic so far! Such a nice community and great science! Including two neurosmiths posters so far. Last one today: @ C89 Alex Price presenting on shared algorithms in human neurons and RNNs. #CCN25 #CCN2025

Seems as good a time as any to re-share the "OpenLists" collection - an openly accessible set of lists of available resources in / for Cognitive Neuroscience! Includes open M/EEG & iEEG datasets & open software / analysis tools, and resources for DSP, Python, git, etc: openlists.github.io

Excited to share our new paper on theta-phase locking of single neurons during human spatial memory: www.nature.com/articles/s41... With @lukaskunz.bsky.social, Joshua Jacobs, and our colleagues from the University of Freiburg

I'd argue that the complete story bullshit is not only slowing progress but is harming translational neuroscience Perfect stories on molecules and "circuits" that cause depression, addiction, PTSD and loneliness in mice using crude mouse behavioral phenotypes, have not been clinically translatable

Postdoc job alert! I’m looking for someone with a PhD in neuroscience/psychology, psychiatry, biomed engineering, computational modeling or a related field to join my NIH-funded team at UCLA studying the neural & computational mechanisms of #interoception in anorexia nervosa 1/2

Why? Our model suggests these patterns are baked into the architecture of social media. • We follow users based on posts we see. • We see posts based on others' reposts. • But reposts tend to be reactive, emotional, and partisan. This feedback loop constructs a network of outrage.

Excited to back in the NL next week for my fav conf of the year. We have 3 posters on 1) anatomical gradients of optimism/pessimism across the brain, 2) comparing ai & bio computations around risk & 3) human brain network control of creativity. 🧠🤖

Looks like the neurosmiths have two nanosymposium presentations this year:

🚨 New Preprint 🚨 Targeting intracranial electrical stimulation (ES) to network regions defined within individuals causes network-level effects By Cyr et al. *** Q: Can we use individualized network maps from precision fMRI to modulate a targeted network via intracranial ES? A: Yes! 🧵:

IYKYK 🤣

Check out our new review/perspective (w/ @juangallego.bsky.social & Devika Narain) on neural manifolds in the brain! It was a lot of fun to think through these ideas over the past couple of years, and I'm excited it's finally out in the world! 🔗: www.nature.com/articles/s41... 📄: rdcu.be/ex8hW

We're thrilled to resume our monthly seminar on neural traveling waves next week with Michael Wenzel! Join us on August 5th at 12-1p ET!

Learn about & be aware of power dynamics and don't be a bully

We put out this preprint a couple months ago, but I really wanted to replicate our findings before we went to publication. At first, what we found was very confusing! But when we dug in, it revealed a fascinating neural strategy for how we switch between tasks doi.org/10.1101/2024.09.29.615736 🧵

Unita mountains timeline cleanse: Happy Friday!

This summer my lab's journal club somewhat unintentionally ended up reading papers on a theme of "more naturalistic computational neuroscience". I figured I'd share the list of papers here 🧵:

This study establishes how aperiodic activity, a ubiquitous signal linked to neural noise, develops in localized brain regions and illuminates the development of prefrontal control during adolescence in the development of attention and memory.

This preprint is now out @braistimjournal.bsky.social www.sciencedirect.com/science/arti...

We @smfleming.bsky.social, Marion Rouault and @seowxft.bsky.social and I) have posted a reply osf.io/preprints/ps... to a preprint that recently raised concerns about the validity of associations between mental health and metacognition from online studies. I hope you can take the time to read it.

APHA is gathering grants by TOMORROW NOON for Phase 2 of their lawsuit vs. NIH which regards NIH **applications** that were unfairly pulled from review, mishandled, or delayed from being awarded due to DEI issues. To add your grant to this lawsuit, become an APHA member & submit this survey:

Check out Justin's presentation on his innovative work from our lab characterizing single human neuron responses to theta burst stimulation of the basolateral amygdala, in collaboration with his home lab in the psych department. www.youtube.com/watch?v=xhSJ...

New preprint from the team at BCM Neurosurgery, led by superstar neuroscientist / neurosurgeon Vigi Katlowitz! “Attention is all you need (in the brain): semantic contextualization in human hippocampus” 🧵 www.biorxiv.org/content/10.1...

Happy Juneteenth🤎✨️

Anti-ICE protesters march through downtown Salt Lake City FULL STORY: bit.ly/4kWPBlE

I taught a graduate course on executive function (EF) in the spring. Before I forget, I thought I'd tell you about the readings students liked the best (at the end of the semester, I asked students to vote for their favorite papers, excl. any of mine). Here are the top vote getters. 🧵 (1/6)

👀 The whole brain 7T "natural scenes dataset" now has mental imagery data! NSD-Imagery: A Benchmark Dataset for Extending fMRI Vision Decoding Methods to Mental Imagery Conference paper: goo.gl/scholar/wPx1HJ Dataset: naturalscenesdataset.org

neuroscience and eng friends, I’m hiring for science’s nascent BCI team! come work with me 🧠🧪👩‍🔬 science.xyz/careers/bci-...

Best overall slide from Dr. Ikeda at #ictals2025

The President's Budget request as released yesterday will gut scientific research. Why should you care? 1) Science is fundamentally a jobs program. Many 100,000s are employed to do science and work for you, the US taxpayer.

Here’s a little desert happiness for your TL. Have a great Friday!

I'm very pleased to share our latest study: ‘Emergence of Language in the Developing Brain’, by L Evanson, P Bourdillon et al: - Paper: ai.meta.com/research/pub... - Blog: ai.meta.com/blog/meta-fa... - Thread below 👇

Please RT🙏 Reach out if you want to help understand cognition by modelling, analyzing and/or collect large scale intracortical data from 👩🐒🐁 We're a friendly, diverse group (n>25) w/ this terrace 😎 in the center of Paris! See👇 for + info about the lab We have funding to support your application!