Any suggestion for a particularly good anti-H3K4me3 antibody for immunostaining in Drosophila? Lately we have been using AB8580 (rabbit) that works well (i need to double check the batch number), but it is a bit dirty (punctuated staining in cytoplasm). Thanks!!!!

“Part of what happens with a lot of this stuff is it's sort of like being too early to the party," says Gustavson. "Because of their [Eastman Kodak's] research labs and innovative nature, they tended to create things that, were ahead of the curve, not behind it." www.bbc.com/future/artic...

Is there any Drosophila species known to naturally specify more than one oocyte per egg chamber? I’ve been looking through the literature but haven’t found any exceptions. Does an oddball species exist, or is the ‘one-oocyte-per-cyst’ rule truly universal across the genus?

C. elegans researchers were early adopters of open science: "The development of common resources and the belief that research findings and mutant strains should be freely shared has propelled worm research to the forefront" www.pnas.org/doi/10.1073/...

🦣🧬🦣🤯💥We are pleased to share our new paper about ancient RNA expression profiles from the Woolly Mammoth, now published in Cell @cellpress.bsky.social www.cell.com/cell/fulltex... If you want to know more, read the 🧵 below:

TT faculty job opening in #Neuroscience! We are looking for a colleague to join us in our fantastic Biology Department and Neuroscience Program at Brandeis. We are a group of *very* collaborative, supportive, and productive scientists (& humans!) so please apply academicjobsonline.org/ajo/jobs/30961

🪰 A new ‘Eyemap’ developed by a team led by Arthur Zhao & @michaelreiser.bsky.social reveals how visual information detected by the fly’s eye shows up in neurons deep in the brain. Remarkably, the eye’s shape determines how flies see motion.👁️ 🔗 hhmi.news/4kSZjou

Most migratory birds are gone but its still a gorgeous place do visit - Boquilobo Bog Natural Reserve.

Not today, parasitic #wasps!✋🚫 #Stinkbugs use a fungus-carrying organ on their hind legs to coat their eggs in #fungi🍄🦵 This provides a physical defense against #parasitic wasp oviposition🛡️ www.science.org/doi/10.1126/...

Faculty positions in animal morphogenesis that may be filled at the Assistant or Associate Professor level in one of my favorite Departments" Cell and Systems Biology at the University of Toronto. 1/n jobs.utoronto.ca/job/Toronto-... jobs.utoronto.ca/job/Toronto-...

Are you interested in a PhD in the area of "Mechanisms of translational control during embryogenesis?" Apply now for a PhD @mpi-cbg.de! Overview of all participating RGLs: imprs.mpi-cbg.de/5761/researc...

#FossilFriday ‘Black Beauty’, one of the smallest-known specimens of Tyrannosaurus rex, displayed at The Royal Tyrell Museum in Calgary, Alberta. wp.me/p3ihHu-1MX

Quick Drosophila question: I’m planning to integrate a construct on the second chromosome but would like to avoid the attP40 landing site. Any suggestion for a good alternative attP site on chromosome II? It’s for a skeletal-muscle–related project. Thanks! 🙂 Rui

Our latest issue is out!👇 www.cell.com/current-biol... On the cover: Nautilus ≈ 🐙+🐚 (Maybe — like the Nautilus — our journal is a living fossil, believing in the interest and inspiration our readers might draw from the diversity of biological systems, questions and approaches we try to feature🙏 )

Very excited to share an excellent review from @teresa-urli.bsky.social, published one week before her PhD defense! We did a deep dive into the fascinating biology of the variant Polycomb complex, PRC1.6 (1/5) journals.plos.org/plosgenetics...

Chart from last year... No big change in % of US applicants, or? . marie-sklodowska-curie-actions.ec.europa.eu/news/msca-po...

📰 New paper alert! In a collaborative project with the lab of Clemens Plaschka at the IMP, the lab of Julius Brennecke has revealed how PIWI proteins kickstart transposon silencing in reproductive cells. The findings are published in Molecular Cell: www.sciencedirect.com/science/arti...

Living organisms are assumed to produce same-species offspring. A study in Nature reports a shift from this norm in Messor ibericus, an ant that lays individuals from two distinct species. go.nature.com/3V68MP0 🧪

Microtubules in Asgard archaea (h/t @lanzen.bsky.social) www.cell.com/cell/fulltex... #jcampubs

I hope everyone on the other side of the Earth is enjoying the total lunar eclipse! Except for flat Earthers.

Yesterday me and my lab celebrated #20years @mpi-cbg.de. There is a lot to say about that but the pictures from the event tell it better. Thanks city of #Dresden for the nice fireworks. That was unexpected. 10 more years or so? #LoPaTs 💕

We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)

🚨 New from our lab: Here we explored how aging contributes to harmful protein aggregation in diseases like Huntington’s & ALS. The culprit? An overlooked aging factor — EPS8 and RAC signaling. #Aging #Longevity #Proteostasis #ALSResearch 🧵 www.nature.com/articles/s43...

Private tour of the Louvre is a special treat. They were vacuuming the Sphinx. You may not have seen a Sphinx being brushed, so I am sharing.

Our new preprint is out ! We uncover how adult Drosophila muscles respond to injury through a coordinated dialogue between hemocytes, tracheal cells, and muscles. Check it out and please share @igdrennes.bsky.social

The chromatin remodeller CHD4 controls both nucleosome integrity and transcription factor binding to promote activity of active regulatory elements and to prevent activation of silent enhancers https://www.biorxiv.org/content/10.1101/2025.08.29.672645v1

Excited to see this published with additional data following our preprint a while back. Cool combination (in our biased view) of controlled TF expression and machine learning to decode chromatin sensitivity. www.sciencedirect.com/science/arti....

Land of Port wine (Alto Douro Vinhateiro)

Our department is advertising two academic positions. Come join us in beautiful Reykjavík. I can promise a very positive collegial atmosphere! #assistant_professor #physiology #cell_biology #physiology #neuroscience euraxess.ec.europa.eu/jobs/368529

"And it wouldn’t matter if CO2 were higher or lower than it is today, or whether the Earth was warmer or cooler as a result. It’s the rate of change in CO2 that gets you to Armageddon." www.theguardian.com/environment/...

Drosophila COMPASS Complex Subunits Set1 and Ash2 Are Required for Oocyte Determination and Maintenance of the Synaptonemal Complex www.mdpi.com/2221-3759/13...

Sex-reversal in birds (genetically male/female but appear female/male) is surprisingly common. Best detail: A genetically male bird called a laughing kookaburra had recently laid an egg. (1/2) By @phiejacobs.bsky.social on @science.org

Evolution is more like a tinkerer than an engineer. New things happen not by perfect engineering but by working with what's already available and repurposing existing objects through recombinations and modifications. This is a classic lesson for any kind of innovation, including that of new ideas..

I just got the notice that all the FlyBase people at Harvard, including me, will be laid off on October 12. I'm devastated.

Interested in pursuing a PhD to study the epigenetic functions of the meiotic synaptonemal complex? This research position offers an excellent entry point! The application deadline is 15 September. euraxess.ec.europa.eu/jobs/365827

To have this paper appear the same day that RFK Jr is canceling all mRNA vaccine funding is further indication that irony is not dead, even though we might all be soon.

A remarkable paper. Davisson and colleagues describe an in vitro reaction running under plausible prebiotic conditions that efficiently and stereoselectively aminoacylates a model tRNA. This suggests a path through which nature may have chosen L vs. D amino acids! www.biorxiv.org/content/10.1...

“Sleep, like ageing, may be an inescapable consequence of aerobic metabolism.” www.nature.com/articles/s41...

To better treat cancer, we need to understand its underlying biology. Despite decades of research, some fundamental questions remain unanswered. One is why certain key tumor suppressor or oncogenes lead to cancer predominantly in single tissue: e.g. Rb in the retina, or APC in the colon 1/n 🧪

🆕🧪‼️ New lab preprint! We study how germ cells (the cells that give rise to gametes, in this case sperm) are supported by somatic (non-germ) cells of the gonad. This matters for our understanding of reproduction - without germ cell development, animals are sterile. www.biorxiv.org/content/10.1...

pYtags - our in vivo biosensors for receptor tyrosine kinases - in all their beauty on the cover of Cell Reports! Read more here: www.cell.com/cell-reports...

A huge project has analysed more than 1,000 claims about the immunity of Drosophila fruit flies in scientific papers published over some 50 years go.nature.com/4lxhwJB

The Angel of Death (a winged skeletal creature) drops some deadly substances into a river near a town, symbolizing typhoid. Watercolor, 1912, by Richard Tennant Cooper. Typhoid was prevalent in the 19th and early 20th centuries, before people had regular access to clean water.