👇 our newest preprint. A tour de force by Valeria to bring OOPS into primary T cells. With new MS analysis pipeline PROMOGEB from Koos allowing for multivariate comparisons. AND interesting biological outcomes. Enjoy! #Tcells #RNA #Immunology #RBP @oncodeinstitute.bsky.social @erc.europa.eu, LSBR

👇See our newest study: What was supposed to be a control experiment uncovered a new function of mTOR: 3’mediated translation control in primary human T cells, mediated through DDX21. AU-rich elements are required for this effect. Happy reading! authors.elsevier.com/a/1mDFf3vVUP...

Very concerning. New research coordinated by the European Broadcasting Union (EBU) and led by the BBC has found that AI assistants – already a daily information gateway for millions of people – routinely misrepresent news content no matter which language, territory, or AI platform is tested.

T-cell smFISH: @anilevetu.bsky.social, @monikawolkers.bsky.social et al present an optimized workflow for simultaneously quantifying nascent and mature mRNA, and its localization with single-cell resolution in human T-cells #RefereedPreprint c/o @reviewcommons.org www.embopress.org/doi/full/10....

I am super proud that this paper is now out in EMBO Journal lnkd.in/ev843k7P What did we do? we optimized imaging of single molecules, in our case cytokine mRNAs with smFISH in primary human T cells.

Somehow we don't talk about this enough.

our study on #gdTcells in pediatric neuroblastoma is out! In contrast to adult tumors, it is the gdTcells that not only expand, but that are the most tumor reactive #TILs. #immunology #tumorimmunology funded by KIKA, Sanquin and supported by Oncode www.life-science-alliance.org/content/8/11...

our study on #gdTcells in pediatric neuroblastoma is now out in

Unvaccinated citizens in the 50s

Kharkiv right now. Moscovia bombs sleeping families. 4 victims including kids. Don’t tell me about peace that Putin wants. Do not dare.

Can you boost the protein expression in specific cell types? That is what we asked in our study published a week ago in @scienceadvances We used machine learning (AI) to learn the code for protein expression in immune cells. www.science.org/doi/10.1126/...

👇New preprint: Proximity labeling in human T cells uncovers ZFP36L1 as central hub for post-transcriptional gene regulation. We found known and unknown ZFP36L1 interactors, their interaction dynamics and RNA (in)dependency, elucidating ZFP36L1's multifaceted role. www.biorxiv.org/content/10.1...

it is finally out! 👇 our #ML pipeline SONAR, which can predict the protein abundance in #immune cells. Using sequence features present in the #RNA. With @bnicolet.bsky.social Supported by the @erc.europa.eu [email protected] www.science.org/doi/epdf/10....

super proud of Kaspar for receiving the VENI grant from NWO-ZonMW. And I am very excited to see what he will find! www.linkedin.com/posts/sanqui...

When birds saw humans give an injured bird special treatment.😅

Bekijk Stop de asielwetten op groenlinkspvda.nl/petitie/stop...

The unparalleled @bsilvasantos.bsky.social concludes the amazing #gammadeltatoronto with the keynote talk. A moment I've waited for since may2022 inaugural #gdtcellclub talk. Super excited to see the wrap up for the unbelievable conf thanks to JC and the other fellow organizers. Let's go!!

Job opportunity at our institute at the University of Amsterdam: www.academictransfer.com/en/jobs/3519...

👇super nice work on TCR-pMHC prediction by the Schumacher lab. Congrats!

happy #dayofimmunology! It also happens to be my birthday and guess what my profession is - could not be better fitting, no?!

The myth that the childhood vaccine against measles, mumps, and rubella (MMR) causes autism is based on a discredited study falsely linking the vaccine to autism. Find out more: ow.ly/EqeC50VlKva. #ImmunologyExplained #Measles #MedSky #MMR

And yet Joe Rogan puts guests on who say "Vaccines aren't actually responsible for the reduction in infectious diseases.”

🇬🇧 UK #scicomm community, I need you! We've rebuilt a small community here for @pintofscience.uk , but it's nothing like what we had on Twitter 🫠 🙏If you feel like it, please share yesterday's post, follow the account, spread the word, etc.. It would help us A LOT to launch #pint25!! THANK YOU 🫶✨️

Ahead of Germany’s election, with anti-immigrant sentiment rising, they released viral videos showing life without immigrants. History proves that when a country starts erasing certain people, it doesn’t end well. 🧵

🚨 New EJI-EFIS Prize for ECRs! 🚨 🏆 €5,000 award for the best research article in EJI by an Early Career Researcher! 🎤 Winner presents at ECI + receives an EFIS–EJI travel grant! 🔗 Apply now: onlinelibrary.wiley.com/page/journal... #ECR #Immunology #EJI #EFIS #ScienceFunding

Learn about our new research uncovering #fungi and plant trade systems, and hear from 3 of the authors. Watch the video: youtu.be/tOUhu2tXIWg?...

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.

If you're a non-UK scientist who wants to come to the UK for a postdoc, this year's Newton Fellowships are now open. You'll need a lab to host you (which could be me, but truly, could be any PI, so get in touch with someone you'd like to work with!) royalsociety.org/grants/newto...

👇 new preprint from our lab What did we find? it is gd T cells that display anti-tumoral activity in pediatric neuroblastoma. ab T cells don't do so much. www.biorxiv.org/content/10.1... a great collaboration between Judith Wienke, David Vermijlen, and us, with support from KIKA and @Sanquin

day 16 #books #bookChallenge #booksky

day 13 #books #booksky #bookChallenge Kleiner Mann- was nun?

wanted to keep this free of politics - but i cannot. HOW DARE HE. We have enough fascists in power, and don't need more of them. So i of course signed. secure.avaaz.org/campaign/de/...

Bring Light back to Ukrainian Schools Christmas Fundraiser: Power generators to keep 112 Ukrainian schools light and warm. u24.gov.ua/bring-light-...?

👇our newest pre-print by Nordin Zandhuis. Depleting the sister proteins ZFP36L1 + ZFP36L2 from effector T cells results in super cytokine producers, even when continuously activated. Yet, it's detrimental for the cells, resulting in poor in vivo survival. Proteomics provides some mechanistic clues.

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers. #2

We are looking for new group leaders. If RNA is your thing, and/or computational biology and you want to start your own group, check out these links. Feel free to contact me about these! And, please help me spread this. Thanks! www.imb.de/jobs/jobdeta... www.imb.de/jobs/jobdeta...

A very rare position for an immunology professorship at Cambridge. Something to think about! www.jobs.cam.ac.uk/job/49381/

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers.

time to try this platform and see whether we can rebuild the scientific community we had and I so cherished here. looking forward to reconnect!