New online: AlphaSync is an enhanced AlphaFold structure database synchronized with UniProt

The stringent response does not influence ribosome pausing in Bacillus subtilis @narjournal.bsky.social from Leendert Hamoen academic.oup.com/nar/article/...

🦠🔬🤖🧑‍💻 #mAIcrobe is out! With @pinholab.bsky.social's lab, we launched an open-source framework for high-throughput bacterial image analysis. By rockstars A. Brito & B. Saraiva et al, making #DeepLearning for phenotyping accessible! Easy to use, plus model training 📜 www.biorxiv.org/content/10.1...

A global view of morphogenetic peptidoglycan synthases across the domain Bacteria Open Access @femsjournals.bsky.social microLife by Francisco García-del Portillo et al academic.oup.com/microlife/ad...

This work is finally published! 🥳🧬 Plasmids are associated with very variable fitness costs in their different bacterial hosts. But, what is the contribution of each of the plasmid-genes in these host-specific effects? Study led by @jorgesastred.bsky.social, @sanmillan.bsky.social and myself! 1/14

Our paper on the Bacteroidota BAM complex is out in @natmicrobiol.nature.com! With @madejmar.bsky.social We found that BAM in Bacteroides and Porphyromonas gingivalis has a distinct architecture from BAM in Proteobacteria. doi.org/10.1038/s415...

Proud of our new study out in @cp-cellreports.bsky.social! Using E. coli lacking all 8 endopeptidases, we provide direct evidence that peptidoglycan expansion during elongation requires ED-mediated insertion of one glycan strand at a time. This can be performed by MepS, MepM, MepH and PBP7 #microsky

(p)ppGpp-dependent activation of gene expression during nutrient limitation #mBio from Jonathan Dworkin journals.asm.org/doi/10.1128/...

Congrats @herailquentin.bsky.social

Excited to present our new study on the mechanism of lateral peptidoglycan expansion in B. subtilis. We combined microscopy visualisation with clickable D-Ala-D-Ala analogues and stable-isotope peptidoglycan labelling to describe an inside-to-outside expansion model @natcomms.nature.com.

Very excited to share our work on (p)ppGpp-mediated resistance to beta-lactam antibiotics published in Nature Microbiology!! A great outcome for a project we started working on 5 years ago. A big thank you to all authors that participated in this study! www.nature.com/articles/s41...