Proud of our new study out in @cp-cellreports.bsky.social! Using E. coli lacking all 8 endopeptidases, we provide direct evidence that peptidoglycan expansion during elongation requires ED-mediated insertion of one glycan strand at a time. This can be performed by MepS, MepM, MepH and PBP7 #microsky

Thrilled to announce our new paper with M. Ethève-Quelquejeu's lab @upcite.bsky.social published @chemistryeurope.bsky.social! We report on the synthesis, and testing by HRMS, of new β-lactam prodrugs, a proof of concept for designing drugs targetting specifically β-lactamase-producing pathogens.

Check out our study on combination of amox, imi and relebactam to treat M. abscessus! Our findings constitute the basis for a clinical consideration of this treatment. This could be consequential for treating infections in cystic fibrosis patients @vaincrelamuco.bsky.social doi.org/10.1093/jac/...