Curious new paper entitled "miRNA modules for precise, tunable control of gene expression": Molecular Cell www.cell.com/molecular-ce...

This is such a beautiful paper.

Just arrived in Florence for CETAF59 @eurotaxonomy.cetaf.org and I am looking forward to present The Arctic University Museum of Norway as a new member! cetaf.org/cetaf59-gene...

Our latest work is now online in NSMB: maternal yolk carries microRNAs from the intestine to embryos, shaping gene regulation and stress resilience in the next generation. rdcu.be/fj8Er #Epigenetics #microRNA #Inheritance @pasteur.fr @devstempasteur.bsky.social @erc.europa.eu

0/ 💡💡💡Had one of those slightly weird moments reading something today. Two seemingly very different research traditions—starting from opposite directions—appear to be converging on almost the same conclusion about one of biology’s biggest questions: How do genomes generate phenotypes? 👇🧵

Very happy that my article „A renaissance of microRNAs as taxonomic and phylogenetic markers in animals“ is among the top 10% read articles in 2024 of Zoologica Scripta @wiley.com onlinelibrary.wiley.com/doi/full/10....

🔥🔥🔥PREPRINT OUT🔥🔥🔥 microRNA annotation gets much easier!!! MirMachine 2 is out! Preprint: doi.org/10.64898/202...

Your time will come. 🗃️🎓

From tunicate microRNAs to museum specimen, from organisms that should not have microRNAs to pills that might. Wetlab and drylab - he can do it all! Thank you also this time for your visit @pedromartinezserra.bsky.social - I am very grateful for your interest and help on these cool projects!

Cool hypothesis on the evolution of complexity: the genome as the original germline (or, the proteome as the original soma)!

Science has missed a real giant. Not uncontroversial, but inspiring nevertheless. Here is an interview which was recorded a few days before his death. www.youtube.com/watch?v=Zxg3...

Topple the system! www.nature.com/articles/d41...

#Biocuration2026 day 4 ended with this beautiful group picture being released and an amazing conference dinner

Given the experience with MirGeneDB we can fully support this list of traits required to become a biocurator by Frederique Lisacek‘s presentation remembering Amos Bairoch at #Biocuration2026.

Third day of #Biocuration2026 kicks off after two days with very inspiring workshops. 140 delegates from >20 countries come together for the 19th annual Biocuration conference (fist time in Africa)!

🚨New course alert! Discover how to go from raw small RNA-seq data to high-quality microRNA annotations in our hands-on online course with @frommlab.bsky.social (6–9 Oct). www.physalia-courses.org/courses-work... #Bioinformatics #RNAseq #MicroRNA #Genomics

Second day of #Biocuration2026 started with workshop on data commons, meshes and Hubs with Gen3

@pedromartinezserra.bsky.social presenting cool work on tunicate phylogeny and more during the annual seminar in Natural Sciences at the Museum here in Tromsø

Come join us in Stockholm as a PhD student for the next 4 years!

after much deliberation and giving AI the benefit of the doubt, Wikipedia editors have had enough of AI slop. New policy bans LLM generated content, periodt www.404media.co/wikipedia-ba...

Very nice tthat the invited review 'A renaissance of microRNAs as taxonomic and phylogenetic markers in animals' by B. Fromm met the interest of our readers and is among the top downloaded papers 2024/2025. onlinelibrary.wiley.com/doi/full/10.... @frommlab.bsky.social @wileyecology.bsky.social

Back in the noughties when I was an academic, my lab did quite a bit of work on (conserved) alternative transcripts. This study in @plosbiology.org presents compelling evidence that most alternative transcripts are deleterious noise journals.plos.org/plosbiology/...

🔥 New Paper out 🔥 How do genomes give rise to the diversity of life we see around us? #EvolutionaryBiology #Genomics #EvoDevo #microRNA #Evolution #SystemsBiology www.journals.uchicago.edu/doi/full/10....

Nature research paper: The E3 ubiquitin ligase mechanism specifying targeted microRNA degradation go.nature.com/4seIEQN

Our work on the E3 ligase mechanism of target-directed microRNA degradation is now published! Amazing collaboration with Brenda Schulman’s lab led by @jakobfarnung.bsky.social and @elenaslo.bsky.social, with special thanks to @wyppeter.bsky.social, Lianne Blodgett, and Daniel Lin! tinyurl.com/Z8TDMD

The E3 ubiquitin ligase mechanism specifying target-directed microRNA degradation (TDMD) is now published! 🎉🍾 We, @bartellab.bsky.social and Schulman lab, describe how 2-RNA factors control protein degradation by recruiting an E3 ligase. @mpibiochem.bsky.social www.nature.com/articles/s41...

This is a step forwards into the world of accurate complex models by AI m, at scale, openly distributed. Excellent work by the consortium here !

Some of the main components of Nucleic acids found on asteroids.

Wow! Beautiful story on the serial homologous origin of fins

Head of Engineering, DiSSCo UK based at @nhm-london.bsky.social "This is a rare opportunity to shape the national digital platform that will underpin the UK’s contribution to DiSSCo and unlock the potential of over 140 million natural science collection items." jobs.nhm.ac.uk/Job/JobDetai...

ArcEcoGen making headlines! Our researchers drilled sediment cores from the bottom of Lake Asklundvatnet to read a natural archive of the past ~3000 years www.frostingen.no/overraskende...

this seems to be a very interesting paper on the (reality) and the significance of 5'G micorRNAs for Dicer processing www.nature.com/articles/s41...

Curious paper! „Accessory microRNA byproducts expand RNA interference via microprocessor-mediated cleavage activation“ I was thinking offset reads first, but this does not look like it? Thoughts? www.science.org/doi/10.1126/...

One of the biggest questions in biology is how complex cells evolved about 2 billion years ago. Here's my new story on how scientists are solving the mystery of eukaryotes like us. Gift link: nyti.ms/4qMbo22

Trying to sort out a vexing issue: What a Gene Regulatory Network Is — and What It Is Not ! thenode.biologists.com/what-a-gene-...

See who is back!! @pedromartinezserra.bsky.social

new paper from the Lai lab! Renfu Shang performs careful mechanistic dissection of miRNA cluster assistance and reveals many insights and surprises to this enigmatic regulatory strategy that gives suboptimal miRNAs a boost. if you love Northerns, you'll ♥️ this! 🧬 genesdev.cshlp.org/content/earl...

Happy to see our study out! We define the sequence determinants for miRNA-target interactions in flies and provide a foundation for improving computational prediction of miRNA-mediated regulation in Drosophila. www.nature.com/articles/s41... #miRNA, @natcomms.nature.com, @rti-umasschan.bsky.social

A #parasitic wasp suppresses host pupation by #microRNA-mediated transcriptional silencing of OfE93 onlinelibrary.wiley.com/doi/10.1111/...

Symbiotic (and genomic) entrenchment! www.cell.com/cell/abstrac...

‘Science journals retract 500 papers a month. This is why it matters. A small team of volunteers is tracking thousands of falsified studies, including cases of bribery, fraud and plagiarism’ Ivan Oransky @retractionwatch.com, @alicedreger.bsky.social @thetimes.com www.thetimes.com/uk/science/a...

If you are interested in electron microscopy, registration is still open for the "Electron Microscopy Hands-On Course: sample preparation and imaging of marine environmental samples" at Stazione Zoologica in Naples. WIth great teachers from Naples […] [Original post on biologists.social]

Wow! 167.2 Gb HiFi yield from a PacBio SMRT cell🎉 Are we getting close the record? This run was for the “Genome of Sweden” project, where we're building a national reference dataset from 10 year old biobanked DNA samples🧬🧪

Dreaming of a de novo assembly of your pesky short ancient sequences? 🧬 A new tool, CarpeDeam, may just help your dreams come true. 🧬🖥️ link.springer.com/article/10.1... #MetagenomicsMonday #ancientDNA #aDNA #paleogenomics #bioinformatics

!!!

I can only second this. BUT, what people often are not aware of: Frontiers in Zoology does NOT belong to the rest of the Frontiers in journals. It is the official journal of the German Zoological Society, a BMC journal and founded BEFORE the other Front in. We suffer a lot from this hijacking.

Latest RNAcentral update out! academic.oup.com/nar/advance-...

Permanent Research Group Leader Position, Crete, Greece: Interested to assume long-term responsibilities for the Biodiversity Computing Group www.biocomp.gr I have set up in Crete? Apply now via apella.minedu.gov.gr/en/node/5998 (PDF also in English) - for questions email to [email protected]

Awesome two day course on microRNA annotation and differential expression analysis done in Oslo last week (#OsloBioinformaticsweek2025) done. Participants (and tutors!) were so committed that this turned out a microRNA hackathon and we are drafting a paper!!!! Thanks for the invite!!

Peracarid crustaceans contain multitudes - at least 26000 species. In the open ocean, some have transparent eyes up to half the body size (they see more contrast but less precision). In caves, they lose eyes and enhance their smell processing. Papers next #Crustmas 🧪🦑