Folks following the leucovorin & autism story should be aware of a ton of PubPeer activity on one of the major trials. Many inconsistencies, statistical concerns, etc raised. pubpeer.com/publications...

Great review on The Genetics of Human Handedness: Microtubules and Beyond www.cell.com/trends/genet... - handedness is such an interesting phenotype!

The nature of the relation between mental well-being and ill-being www.nature.com/articles/s41...

📣The National Institutes of Health (NIH) is accepting applications for Director of the National Institute of Mental Health (NIMH). Help us spread the word about this opportunity! 🔗Find more information here: hr.nih.gov/jobs/search/... #jobopportunity #NIMH

Confused writing is usually a symptom of confused thinking. As we struggle to clarify writing, we clarify our thoughts. AI writing aids rob us of that struggle, leaving clean-looking text and thoughts still confused for lack of inspection. Writing is not just a product; it is a diagnostic tool.

So that is why I receive 10 review invitations per month, and it takes -by now- *years* to publish. Discouraging!

If you want to know more about autism and the genetics of autism, feel free to visit: tinyurl.com/hjyyrjtr

(1/9) 📣 OUT NOW! 📣 So excited to share that our systematic review and meta-analysis on the autism polygenic score is now published in JAACAP Open @jaacapjournals.bsky.social. doi.org/10.1016/j.ja... A (long) thread of our main findings ⤵️

Thanks to all co-authors for collaborating, it was a true pleasure!

Extremely proud of @mmdewit.bsky.social for leading this comprehensive study on the #autism #polygenic score. Check out the interactive tool to easily find the association with your phenotype of interest!

We are currently looking for new collaborators with genotyping and autism data in order to increase our sample size for our next large-scale genome-wide meta-analyses of autism. Want to contribute? Contact us! 📩 pgc.unc.edu/for-research...

Our goal is to have 1000 SUFS Teach Ins across the US, by 9/30. *GASP* 😮 We know, it's a big goal. If you've received tax dollars for your science, you have a responsibility to inform *your* community what is at stake: public health, the economy, innovation, and America's global leadership.

The genetic basis of human height www.nature.com/articles/s41... (read free: rdcu.be/egGQf) 🧬🖥️🧪

Visit our website to read the latest Letter from the ISPG President, J9. ispg.net/about-us/mes...

In every civilization, people end up sorted into levels of socio-economic status (SES). We explore the history, present, and future of scientific research on the complicated relationship between SES and DNA in @naturehumbehav.bsky.social💰🧬🎓 Link: rdcu.be/efacK Thread below 👇🏽

What a missed chance for @TU Delft. Congrats dr. Rachel Los!

The overall silence of major professional scientific societies while all this goes on is also bewildering. By the time they forcefully speak up, much damage will already have been done. 🧪

Genetic counseling community - lots going on in the US that’s negatively impacting us, science/research, patients & communities. Genetic counseling support call Fri 3/14 at 1pm PT. Safe space (not affiliated w/ any org) to share and listen. If you need the link, DM me or @j9austin.bsky.social

On the 10th of April, Renata Androvicova, @joellepasman.bsky.social and Karin Verweij will host a workshop on the genetics of sexual violence. Join in person or online to discuss the results of the study on the genetic overlap between sexual violence, reproductive traits, and psychiatric traits!

The BGA meeting in Atlanta will now have a hybrid option! 🌍🎥 We've also reopened abstract submissions for 2 weeks, with a hard deadline of March 14, 2025. Join us in person or virtually for a fantastic meeting! Register here: auth.oxfordabstracts.com?redirect=/st... #BGA2025

Have you ever wondered about nonlinearity in bivariate genetic associations? Or wondered whether global estimators like genetic correlations tell the full story about the relationship between two phenotypes, then check out @michelnivard.bsky.social thread on some work we’ve been doing to model this.

Did you know Elon Musk was a Fellow of the Royal Society? Yes, that Elon Musk. Respect to Profs @deevybee.bsky.social & Andrew Millar who have resigned over his continuing membership. And @scurry.bsky.social who has 1300+ scientists signing his open letter to the Society's President (link below)

PhD students in social sciences studying "metascience" and AI: This looks like an *AMAZING* opportunity. Fully funded research postdoc that can be housed at whatever university you can find an appropriate mentor. sloan.org/programs/dig...

Latest blogpost on Musk/Royal Society debacle: deevybee.blogspot.com/2025/02/seve... I look at the reasons that have been given for inaction, and find them wanting. @royalsociety.org

Thanks to the more than *1100* members of the scientific community who have signed the letter to insist that the Royal Society remains true to values that we all hold dear but that Musk FRS has ridden roughshod over. Please keep signing & sharing. docs.google.com/forms/d/e/1F...

Let’s buy California: denmarkification.com

Ireland is now at 84.91% of it's threshold to count as one of the seven #EU countries to get this initiave to ban LGBT conversion "therapy" which means we need 1,383 more signatures here.....#Spéirgorm

‘The health community has overcome huge obstacles many times before to make enormous contributions to humanity’s wellbeing’. On the current (chaotic) status of health research and service, and how we should respond: www.thelancet.com/journals/lan... www.thelancet.com/journals/lan...

Hear hear!! www.bmj.com/content/388/...

Outreach about #autism. With @mmdewit.bsky.social

#ADHD Women’s life expectancy minus 8.64 years (men 6.78 yrs) while, according to the authors, risk factors are likely modifiable. www.cambridge.org/core/journal...

Do people trust scientists? Focus for me: outreach, co-creation, and science communication 📣 www.nature.com/articles/s41...

Promoting healthy aging in women. Prolonging ovarian life. Slowing the onset of menopause. A feature @nature.com www.nature.com/articles/d41... open-access @lynnpeebles.bsky.social

So you got a null result? Welcome to the club! www.nature.com/articles/d41...

Briljant!

Nice work! @mmdewit.bsky.social for your EnWAS. @dr-appie.bsky.social in general 🙂

New preprint investigating how urban-rural living is related to mental health 🏠 led by @adamfinnemann.bsky.social

A permanent job lecturing stats in Psychology at University of Edinburgh (we're a lovely bunch!): elxw.fa.em3.oraclecloud.com/hcmUI/Candid... @schoolofppls.bsky.social

In a @currentbiology.bsky.social paper earlier this year, led by @laurawesseldijk.bsky.social, we analysed Beethoven’s genome with a polygenic index related to musicality, as a way to communicate limits of genetic predictions at the individual level & the complexity of links between DNA & behaviour:

"Women full professors are 19% more likely than men at the same career stage to leave academia, as compared with 6% for women assistant professors and 10% for associates."

BROADEN WHO YOU CITE. IT MATTERS.

Outreach in psychiatric genetics - What is it? Why do we need it? How can we do it well? Join me, Niamh Ryan, and Cindy Bulik this Friday (6th) at 10am EST / 4pm CET / 3pm UTC where we'll discuss all of this for the PGC (@pgcgenetics.bsky.social) World Wide Lab 🌎 🔗 us02web.zoom.us/j/88690327502

Worrisome problem, nicely illustrated

A growing problem --- fake papers polluting systematic reviews. And interesting point that the gold-standard protocols that Cochrane is developing to weed out untrustworthy studies, are too much of an effort for systematic-review authors looking at 100s of papers. www.science.org/content/arti...

Solid empirical data on mental disorder trends 👇🏼

A hugely important study for women by (mostly!) women ❤️https://www.nature.com/articles/s41586-024-08035-2

WHO just released the new principles for ethical collection and sharing of genomics data www.who.int/news/item/20...

I am co-leading a very hands on short course (5 days spread over 2 weeks) on Genetic Epidemiology through the Bristol Medical School. There is a discounted rate for students from for lower and middle income countries. direct link to sign up: www.bristol.ac.uk/medical-scho...

FinnGen continues to be one of the best genetic datasets in the world with some of the best phenotype data, and now they've reached their goal of 500k (same size as UK BioBank)! Truly, the gift that keeps on giving www.finngen.fi/en/results-b...