Our new non-denaturing nanoscale 3D DNA tracing technology provides single-cell (and sister-chromatid specific!) readout of chromatin structure with 10kb genomic resolution - Check it out! www.nature.com/articles/s41... Congratulations to Kai and Oyvind!!

We’re very excited about the potential of IACS for advancing infectious disease research and believe this review from the Goda lab and its collaborators in @natrevbioeng.nature.com highlights its many powerful applications. Check out the full paper here: www.nature.com/articles/s44...

We found a new asymmetry in the large-scale chromosome structure: sister chromatids are systematically shifted by hundreds of kb in the 5′→3′ direction of their inherited strands! The work was led by Flavia Corsi, in close collaboration with the Daniel Gerlich lab. www.biorxiv.org/content/10.1... 1/

We’re excited to share our review: "Next-generation genetic screens in kinetoplastids", now published in NAR! It covers a range of perturbation methods—from RNAi to prime editing—as well as emerging assay technologies like scRNA-seq and image-activated cell sorting. academic.oup.com/nar/article/...

Are you based in the U.S. 🇺🇸 or Canada 🇨🇦 and thinking of doing research in Europe? ERC grants offer up to €4.5 million to support groundbreaking, investigator-driven frontier research in all fields. Watch the dedicated info session for researchers in your region👉 youtu.be/92QYink1Lik #ChooseEurope

New online! RNA splicing — a central layer of gene regulation

Nature research paper: Chromatin loops are an ancestral hallmark of the animal regulatory genome https://go.nature.com/4kcNObU

These boxes are not moving. A mind-bending optical illusion by Japanese artist Jagarikin.

Our latest collaborative work with Keith Matthews’ lab using synthetic DNA binding proteins to explore the chromatin protein contexts of repetitive sequences in Trypanosoma brucei in now on bioRxiv - thanks to all involved! 2025.04.22.649942; doi: doi.org/10.1101/2025...

Very much looking forward to it.

Register for the excellent Epigenetics Gordon Research Conference Barcelona 10-15 Aug25. Theme: Epigenetic Variation: Mechanisms & Impact Across Systems. **FUNDING AVAILABLE to support attendance** ~15 talks to be chosen from submitted abstracts, so upload yours ASAP: www.grc.org/epigenetics-...

In the silence of chromatin, Toxoplasma whispers change. TgSNF2h sculpts the genome - MORC in the backseat. Some genes wake. Others sleep. A dance of nucleosomes shaping space for life parasite stages to unfold. Now in Nature Microbiology: rdcu.be/ehkWp

Here is-🥳🥳😇 tremendous effort by @palmrinmoy.bsky.social brilliantly supported by @tamas-schauer.bsky.social &super help by federico,iliya,tsune,adam,@mamartirenom.bsky.social Very happy to see this come to fruition- Look forward to feedback from colleagues ! More 👉 www.cell.com/cell/fulltex...

Great work.

If you are interested in antigenic variation, you may have wondered how parasites ‘select’ which antigen to express next. Our manuscript, just published in Nature, provides some answers! www.nature.com/articles/s41... @lmumuenchen.bsky.social @erc.europa.eu a.eu @nature.com

#AidJobs: We are hiring, here is your chance to work with us. International Secretary General: bit.ly/42VhaWN Deputy Logistics Coordinator: bit.ly/4gIVDUf Tembo Support Officer: bit.ly/4gJ9WIK 5 Nutritionists- bit.ly/3CVtzPW Finance and Human Resources Manager: bit.ly/3QjZLzo

Hope we can join this meeting again this year.

Save The Date : The Next EMBO Workshop « Host-parasite relationship: from mechanisms to control strategies », organized by @ParaFrap, will be held October 5-8, 2025 @EMBOevents #Science #Parasite #France

How is transport directionality achieved through the #trypanosome nuclear pore complex? The current model is symmetrical, but this study reveals that the trypanosome #NuclearPore has an asymmetrical architecture, with conserved hubs that direct mRNA transport 🧪 @plosbiology.org plos.io/3Q36QV2

Please RS/RT. #GordonConference "Histone and DNA Modifications" Program is now online 🍾 #epigenetics #chromatin #histones 20.-25. July. Il Ciocco 🇮🇹 Register now: ➡️ shorturl.at/AtAjz Exciting speaker lineup, many slots for talks selected from abstracts

I’m very much looking forward to attending the symposium and to celebrate the career of Mark Carrington.

We have a feeling you'll be interested in this one. Nature is keen to find out how scientists are using Bluesky and whether it has become their go-to social-media platform. Take the survey! 🧪

That is why we left.

🚨 Final abstract submission by tomorrow for #BSP2025 in Würzburg! 🚨 - Abstract submission by 𝟏𝟓𝐭𝐡 𝐉𝐚𝐧𝐮𝐚𝐫𝐲 𝟐𝟎𝟐𝟓 at tinyurl.com/5c2jn5zs - You can register (early bird registration until the 10th February) at tinyurl.com/3x32vycr

Have you finished your #PhD and are interested in exploring how #parasites cross the vasculature to colonize tissues? Do you fancy catching some #waves in the Atlantic? Or eating grilled fish by the beach? Join us in #Lisbon at GIMM, where science meets quality of life. @parasitesrule.bsky.social

It is a great honour to invite you to a symposium to celebrate the career of Mark Carrington. An exciting set of talks, particularly if you are fascinated by trypanosomes.

Our paper is out! We used Micro-C to study the 3D genome organization at high resolution in trypanosomes and revealed an extensive network of inter-chromosomal transcription hubs. read more at doi.org/10.1038/s414... 🧬 Great work from @claudiarabu.bsky.social @naturecomms.bsky.social

Great work

Genes linked to deadly parasites’ spread beyond Africa identified. Parasites that cause the deadly illness known as sleeping sickness can spread beyond their native Africa as a result of mutations to key genes. @keithrmatthews.bsky.social @goldrieve.bsky.social Full article: shorturl.at/9jlGS

Final version of paper n1 is out 🎉 so many pooled CRISPR screens are done worldwide, on the host and on pathogens, and we wondered whether interactions between KOs mask phenotypes: they do! We found out that for Toxo a lot of efforts are spent on fine tuning the environment in a paracrine way

Congratulations to Maria-Elena Torres-Padilla for being awarded the Leibniz Research Prize by the German Research Foundation. www.helmholtz-munich.de/en/newsroom/... @dfgpublic.bsky.social @metorrespadilla.bsky.social @www.helmholtz.de

Have you ever wondered how knocking out every single gene in the human genome, one by one, might affect your intracellular pathogen of interest? We did, & boy was it a wild ride! Happy to share our preprint discovering the essential host genome for Cryptosporidium - www.biorxiv.org/content/10.1...

First paper of our lab today @natureportfolio.bsky.social by Nussi! We provide a real-time movie on how #transcription and #translation cooperate using #single-molecule FM: we find long-range #ribosome/ RNAP communication mediated by #RNA looping! @embl.org #RNAbiology #RNASky t.co/a24Xxcxdo0

Please RS/RT. #GordonConference on "Histone and DNA Modifications" #epigenetics #chromatin 20-25. July 2025. Il Ciocco, Italy. Great speaker lineup. ➡️Register now www.grc.org/histone-and-...

The 2nd edition of the Paris-Munich Epigenetics meeting will be held April 9-11, 2025 in Paris. Attendance is free of charge. Please visit the website www.sfb1064.med.uni-muenchen.de/paris_munich... to find out more about the program and to register. #epigenetics

A great line-up of parasitologists ready to Rumble in the Bluesky Jungle!