ParasitesRule
@parasitesrule.org
📤 258
📥 187
📝 23
Profile picture: Toxoplasma image taken by Omar Harb Banner picture: Plasmodium from Volker Heussler
🔬 Featured Image Trypanosoma cruzi amastigotes (red) infecting a cardiomyocyte (cyan) in a mouse heart, with CD4 (green) and CD8 (magenta) T cells revealing the immune response. 📸 Fernando Sanchez-Valdez, @CTEGD, University of Georgia
parasitesrule.com
5 days ago
1
1
0
🚨🚨🚨Game changer for babesia research from the Mamoun lab: Continuous In Vitro Propagation of the Human Pathogen Babesia microti in Human Erythrocytes
@yalemedicine.bsky.social
@yalepress.bsky.social
www.biorxiv.org/content/10.6...
6 days ago
1
7
2
🌍 Calling parasitologists from LMICs! Apply for the MPM XXXVII LMIC Travel Award to attend the Molecular Parasitology Meeting in Woods Hole, MA (September 13–17, 2026). Awards include full registration, travel, and accommodation. 🗓️ Deadline: March 1, 2026 🔗
www.parasitesrule.com/mpm-xxxvii/t...
loading . . .
Travelaward2026
MPM LMIC award details
https://www.parasitesrule.com/mpm-xxxvii/travelaward2026
21 days ago
1
7
9
🔬 February image is live! Trypanosoma cruzi trypomastigote inside a host cell, captured using ultrastructure expansion microscopy. 📸 Ramiro Tomasina Institut Pasteur de Montevideo Share your parasite images at parasitesrule! 🔗https://www.parasitesrule.com/
about 1 month ago
0
3
0
The deadline to apply to BoP is coming up quickly. Make sure to get your application in by February 5, 2026.
add a skeleton here at some point
about 1 month ago
0
1
0
reposted by
ParasitesRule
Victor Tobiasson
about 2 months ago
FYI were starting weird structure/evolution/biology stuff at Glasgow University! If you're interested let me know! Tell your friends! CRYO
www.jobs.gla.ac.uk/job/research...
BIOINFO
www.jobs.gla.ac.uk/job/research...
TECHNICIAN
www.jobs.gla.ac.uk/job/technici...
#science
#hiring
#evolution
0
7
6
reposted by
ParasitesRule
GadelhaLab
about 2 months ago
If you assume GPI insertion signals = surface destination, trypanosomes disagree. Tom’s work shows GPI-anchored protein sorting occurs independently of GPI insertion signals, hinting at alternative sorting logic at the parasite surface.
tinyurl.com/gpi-anchor
#MembraneBiology
#CellSurface
loading . . .
Sorting of GPI-anchored proteins at the trypanosome surface is independent of GPI insertion signals
The segregation of glycosylphosphatidylinositol-anchored proteins (GPI-APs) to distinct domains on the plasma membrane of eukaryotic cells is importan…
https://tinyurl.com/gpi-anchor
0
9
3
🔬 Our first community-contributed image is here! Stunning SEMs of two Trichomonas vaginalis parasites connected by cytonemes. Want to share your parasite images? Visit
parasitesrule.com
to contribute! 📸 Salas et al., eLife 2023 doi:10.7554/eLife.86067 @eLife
2 months ago
0
6
2
🦠 Calling all parasitologists! New feature:
parasitesrule.com
showcase YOUR research images on our homepage. Whether it's a beautiful microscopy shot, field work, or lab research - share it with fellow parasitology enthusiasts! Submit here:
forms.gle/b3s8bJbQuTZc...
#Parasitology
#SciencePhotography
loading . . .
Parasitesrule
Dr. Roland A. Cooper
https://parasitesrule.com
3 months ago
0
3
0
reposted by
ParasitesRule
Bloodsucking Parasites
3 months ago
Genetic characterization and identification of a recent discovered genotype of Theileria orientalis (Piroplasmida: Theileriidae) in water buffaloes (Bubalus bubalis) from the Amazon region, Brazil Ticks&TBD
loading . . .
Genetic characterization and identification of a recent discovered genotype of Theileria orientalis (Piroplasmida: Theileriidae) in water buffaloes (Bubalus bubalis) from the Amazon region, Brazil
Publication date: January 2026 Source: #ticks and #tick-borne Diseases, Volume 17, Issue 1 Author(s): João Paulo S. Alves, Pedro H.C. Rodrigues, Anisleidy P. Castillo, Antônio A. Fonseca Junior, Cairo H.S. de Oliveira, Rômulo C. Leite, José D. Barbosa, Júlia A.G. Silveira
http://dlvr.it/TPsM0G
0
1
1
reposted by
ParasitesRule
Uni of Nomi
3 months ago
#Parasitologists
! Partake in this free
#training
offered by and for
#VEuPathDB
- an invaluable platform for -omics data and analytical tools centered around some of the most neglected fields of science!
#parasitology
#mycology
#fungus
#pathogen
#vector
#eukaryote
#protists
add a skeleton here at some point
0
4
2
🦠 Grad students & postdocs in parasitology: Apply now for the Biology of Parasitism (BoP): Modern Approaches course at @MBLScience. Hands-on labs, expert lectures, and cutting-edge tools. 📅 Summer 2026 | ⏰ Deadline Feb 5 🔗
mbl.edu/courses
3 months ago
0
14
18
reposted by
ParasitesRule
Anthony Olszewski
3 months ago
"This interview with Dr. Emma H. Wilson details recent findings on how the chronic parasitic infection Toxoplasma gondii (*Toxo*) disrupts neurotransmission in the rodent brain. The study demonstrates ..."
www.youtube.com/watch?v=l6DP...
#Toxoplasma
#Toxoplasmosis
#Parasite
#Parasitology
loading . . .
Professor Emma H Wilson discusses Toxoplasma gondii.
YouTube video by Anthony Olszewski
https://www.youtube.com/watch?v=l6DPivZN9Ys
0
1
1
reposted by
ParasitesRule
University of Glasgow School of Infection & Immunity
3 months ago
🎥 | WATCH | Dr Thomas Hollin (
@umontpellier.bsky.social
) discusses RNA-binding Proteins and Organellar Gene Regulation in Plasmodium falciparum. The full Centre for Parasitology seminar is now available for a limited period on our YouTube channel: 📺
youtu.be/aH9aZAbJaIs?...
loading . . .
0
3
2
reposted by
ParasitesRule
Paul Sigala
4 months ago
Thrilled our study on heme crystal motion in
#malaria
@parasitesrule.org
is now published
@pnas.org
, support from NIH,
@bwfund.bsky.social
,
@uofutahcihd.bsky.social
, UofU 3i. With Fu and Bidone labs
@price.utah.edu
,
@uofubiochem.bsky.social
,
@uofuhealth.bsky.social
www.pnas.org/doi/10.1073/...
loading . . .
Chemical propulsion of hemozoin crystal motion in malaria parasites | PNAS
Malaria parasites infect red blood cells where they digest host hemoglobin and release free heme inside a lysosome-like organelle called the food v...
https://www.pnas.org/doi/10.1073/pnas.2513845122
1
7
4
Missed another parasitology webinar? 😩 I built a page to fix that — a community list of free online seminars anyone can add to! 🧫 Find and share virtual parasitology events here:
www.parasitesrule.com/seminars
5 months ago
1
7
3
reposted by
ParasitesRule
Keith Matthews
5 months ago
We have a 3+ year post doc available in our lab to study trypanosome transmission and virulence. Combined wet lab and bioinformatics expertise preferred. Please apply via the HR link (
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
). Find out more about us in the link below.
loading . . .
The Matthews Lab | Biology
The Matthews Lab
https://biology.ed.ac.uk/the-matthews-lab
0
15
21
The parasitesrule site has an archive of abstract books from the Molecular Parasitology Meeting (MPM) & the Kinetoplastid Molecular Cell Biology Meeting (KMCB). The book from the first MPM (1990) is also there! 🔗
parasitesrule.com/archive
5 months ago
0
6
2
Did you know that you can submit and view parasitology related jobs on the
#parasitesrule
site? Check out the new interface: 🔗https://www.parasitesrule.com/jobs
5 months ago
0
7
1
Interested in Parasitology conferences in 2026? Look no further, check out the list of upcoming conferences on the parasitesrule website:
www.parasitesrule.com/conferences
5 months ago
0
7
1
reposted by
ParasitesRule
Uni of Nomi
5 months ago
Why do we care? Because very little information is available for proteins found in
#parasites
, despite parasites causing a third of the total global burden of human
#disease
(!!!)
#MPM2025
@parasitesrule.org
2/2 More about this problem is explained nicely here:
www.sciencedirect.com/science/arti...
loading . . .
Exploiting structural biology in the fight against parasitic diseases
Despite spectacular advances in structural biology over the past half-century, only approximately 2% of the structures in the Protein Data Bank are fr…
https://www.sciencedirect.com/science/article/abs/pii/S1471492212000153
0
4
3
reposted by
ParasitesRule
6 months ago
You can explore the full scRNAseq data on the same gene page:
cryptodb.org/cryptodb/app...
0
3
2
reposted by
ParasitesRule
6 months ago
The
@veupathdb.org
user comments campaign at
#MPM2025
yielded 200 user comments from 66 attendees! Thanks, contributors 💐 For example: a comment on gene cgd5_3570 on CryptoDB pointed out that GGC proteins exhibit male-specific expression according to single-cell RNA seq. Good to know!
1
6
3
Recordings of the last 5 Keynote talks at the Molecular Parasitology Meeting MPM are available on the parasitesrule Youtube channel - check them out - ❤️ like and subscribe:
www.youtube.com/@Parasitesrule
loading . . .
Parasitesrule
https://www.youtube.com/@Parasitesrule
6 months ago
0
6
1
reposted by
ParasitesRule
Uni of Nomi
6 months ago
How? By inhibiting the uptake of metabolically essential amino acids and disrupting the parasite's lifecycle. You can learn more about some of their work here:
pmc.ncbi.nlm.nih.gov/articles/PMC...
#Parasitology
#MPMXXXVI
#MPM2025
2/2
loading . . .
Computational approaches for drug discovery against trypanosomatid-caused diseases
During three decades, only about 20 new drugs have been developed for malaria, tuberculosis and all neglected tropical diseases (NTDs). This critical situation was reached because NTDs represent only ...
https://pmc.ncbi.nlm.nih.gov/articles/PMC10317681/
0
1
1
reposted by
ParasitesRule
Uni of Nomi
6 months ago
Highlights from
#MPMXXXVI
: Work by Melisa Sayé et al. explores repurposing benztropine - a Parkinson's disease drug - against infection by Trypanosome cruzi, a
#parasite
causing Chagas disease which affects >7 million people worldwide.
@parasitesrule.org
#MPM2025
#Parasitology
1/2
1
1
1
reposted by
ParasitesRule
Uni of Nomi
6 months ago
Learn more about some of their work here:
pmc.ncbi.nlm.nih.gov/articles/PMC...
(Although ginger extract is used in this paper^. If anyone can point me towards publications of their studies using thyme extract please do!)
@parasitesrule.org
#MPM2025
#Parasitology
#MPM2025
#botany
2/2
loading . . .
Efficacy of green synthesized silver nanoparticles via ginger rhizome extract against Leishmania major in vitro
Leishmaniasis is a major public health problem that causes by parasite of the genus Leishmania. The pentavalent antimonial compounds that used for treatment are not safe or effective enough. The aim o...
https://pmc.ncbi.nlm.nih.gov/articles/PMC8372886/
0
1
1
reposted by
ParasitesRule
Uni of Nomi
6 months ago
Highlights from
#MPMXXXVI
: Work by Atena Hesami et al. shows the efficacy of thyme extract incorporated into silver
#nanoparticles
for use against Leishmania major - a
#parasite
causing flesh-eating disease - showing the value of naturally sourced compounds as augmentative antiparasitic agents. 1/2
1
2
1
reposted by
ParasitesRule
Uni of Nomi
6 months ago
Highlights from
#MPMXXXVI
:
#Ticks
! (woot!) Work by Isaac A. Hinne et al. identified stage-specific gene expression profiles in developing
#tick
embryos (Ixodes scapularis). Targeting embryonic development in ticks offers a unique point of
#vector
control.
@parasitesrule.org
#MPM2025
#Parasitology
0
2
1
reposted by
ParasitesRule
Uni of Nomi
6 months ago
Hey,
#MPMXXXVI
attendees! Just a reminder today is the last day to vote for your favourite talks and posters from this year's meeting. I've highlighted a few in my posts below!
@parasitesrule.org
#MPM2025
#Parasitology
0
1
1
reposted by
ParasitesRule
Henrico Langeveld
6 months ago
Honoured & grateful to have received an MPM Travel Grant and have the opportunity to present my PhD research at my first MPM 🇺🇸 Amazing science, inspiring discussions & a fantastic community of parasitologists – what a milestone in my journey.
@parasitesrule.org
#MPM2025
#Parasitology
0
12
3
reposted by
ParasitesRule
Rohit Satyam
6 months ago
Join me on 16 Sept 8-9 AM (Boston time Zone i.e. 3 PM KSA) as I present my R package on how to access VEuPathDB component databases and several other database virtually in MPM XXXVI conference.
rohit-satyam.github.io/plasmoRUtils...
#plasmodium
#pathogen
@veupathdb.org
@parasitesrule.org
0
7
3
Did you submit an abstract to
#mpm2025
? Notifications went out this week. Check you spam folders if you don't see an email in your inbox.
@rmc9z.bsky.social
@mjgubbels.bsky.social
@omarharb.org
7 months ago
0
5
4
reposted by
ParasitesRule
9 months ago
🚀Big News! We’re now offering AI-powered summaries of expression data on gene pages in
@veupathdb.org
See expression patterns and get insights with a single click! 🧬🔎 Go to your favorite gene pages and look for “AI Expression Summary” under Transcriptomics.
loading . . .
0
4
3
reposted by
ParasitesRule
Geoff McFadden
9 months ago
We are developing a simple, very cheap, low tech way to reduce malaria transmission. Instead of giving the antimalarials to people, we give them to the mosquitoes that spread the parasite. How do we drug a mosquito? Read on.
www.sciencedirect.com/science/arti...
loading . . .
Identifying antimalarials that disrupt malaria parasite transmission when fed to the mosquito
A decade-long decline in malaria cases has plateaued, primarily due to parasite drug resistance and mosquito resistance to insecticides used in bed ne…
https://www.sciencedirect.com/science/article/pii/S0020751925000967?CMX_ID=&SIS_ID=&dgcid=STMJ_220042_AUTH_SERV_PA&utm_acid=96694420&utm_campaign=STMJ_220042_AUTH_SERV_PA&utm_in=DM572707&utm_medium=email&utm_source=AC_#f0025
1
20
9
reposted by
ParasitesRule
Bloodsucking Parasites
9 months ago
Three Hungry Tryps: the efficient endocytic pathway of pathogenic trypanosomatids Trends_Parasitol
loading . . .
Three Hungry Tryps: the efficient endocytic pathway of pathogenic trypanosomatids
Eukaryotic cells incorporate various molecules through a process known as endocytosis, which is crucial for the cell's survival and reproduction. While this process has been extensively studied in mammalian and yeast cells, significant contributions have also been made by researchers studying pathogenic protists. This review aims to present the most relevant information about the endocytic process in three important trypanosomatids: Trypanosoma cruzi, Trypanosoma brucei, and Leishmania. Many protozoa exhibit strong endocytic activity across their entire surface. However, in trypanosomatids, this activity is highly polarized and occurs exclusively in the flagellar pocket. In the case of T. cruzi, endocytosis primarily takes place through the cytostome–cytopharynx complex. This process involves an entry site organization of the cytoskeleton, including the participation of specialized microtubules.
http://dlvr.it/TLDqx7
0
2
2
Registration and Abstract submission for MPMXXXVI are now open! Abstract submission deadline is June 27th, get yours in quickly.
@rmc9z.bsky.social
@mjgubbels.bsky.social
@omarharb.org
🔗https://www.parasitesrule.com/mpm-xxxvi
9 months ago
0
21
19
reposted by
ParasitesRule
9 months ago
Make open access to tools and data part of your annual giving by making a tax deductible donation to
@veupathdb.org
. 💙This resource simplifies and supercharges global infectious disease research. Need more reasons to support VEuPathDB? Here's a short list:
veupathdb.org/veupathdb/ap...
0
6
7
reposted by
ParasitesRule
9 months ago
Today, we're highlighting a section of the gene page in
@veupathdb.org
data platforms that allows you to use RNA seq evidence to 🔎🧬examine gene models- making it easy to spot splice variants or incorrect annotation. Take a look!
www.youtube.com/shorts/T0Jis...
loading . . .
Intron spanning reads and gene models
YouTube video by VEuPathDB
https://www.youtube.com/shorts/T0JisZ8aRjw
0
2
2
reposted by
ParasitesRule
9 months ago
Today's short video features the proteomics section of our encyclopedic gene pages. 🧬 Quickly find mass spec evidence, post-translational mods, and more for your favorite gene in
@veupathdb.org
and all of our component databases. Watch it now!
www.youtube.com/shorts/o0s-D...
loading . . .
Proteomics data on gene pages
YouTube video by VEuPathDB
https://www.youtube.com/shorts/o0s-DwUbVnQ
0
2
2
reposted by
ParasitesRule
Author Bill Sullivan
10 months ago
A common parasite can decapitate human sperm − with implications for male fertility
theconversation.com/a-common-par...
loading . . .
A common parasite can decapitate human sperm − with implications for male fertility
If you’ve handled cat litter or eaten raw meat or unwashed produce, there’s a chance you might have a permanent toxoplasmosis infection spread throughout your body.
https://theconversation.com/a-common-parasite-can-decapitate-human-sperm-with-implications-for-male-fertility-256892
0
6
2
reposted by
ParasitesRule
10 months ago
📹We've made more short videos to highlight features on
@veupathdb.org
💫 This one walks you thro' the section on gene pages called the RNAseq transcriptomic summary. Get an overview of datasets where your favorite gene is doing something interesting. Watch it now!
www.youtube.com/shorts/V2eZi...
loading . . .
Gene Page RNAseq Transcriptomic Summary
YouTube video by VEuPathDB
https://www.youtube.com/shorts/V2eZiwFFoJA
0
5
4
reposted by
ParasitesRule
Faria Tryps Lab
10 months ago
So happy to share the first preprint from our lab on post-transcriptional regulation at the VSG expression-site body in trypanosomes.
@ybri-uoy.bsky.social
@york.ac.uk
loading . . .
Specialised RNA decay fine-tunes monogenic antigen expression in African trypanosomes
Antigenic variation is a sophisticated immune evasion strategy employed by many pathogens. Trypanosoma brucei expresses a single Variant-Surface-Glycoprotein (VSG) from a large genetic repertoire, whi...
https://www.biorxiv.org/content/10.1101/2025.05.24.654301v1
2
32
13
reposted by
ParasitesRule
Faria Tryps Lab
10 months ago
We identified 3 novel proteins at the ESB that negatively regulate genes co-transcribed with the active-VSG through specialised and spatially regulated RNA decay.
#RNA
#condensates
#3Dgenome
#RNAdecay
1
5
2
reposted by
ParasitesRule
Faria Tryps Lab
10 months ago
Thanks to all involved, particularly
@liannelansink.bsky.social
who worked really hard in the past 3 years &
@trypsleon.bsky.social
and our funders
@wellcometrust.bsky.social
@royalsociety.org
@parasitesrule.org
0
3
1
reposted by
ParasitesRule
11 months ago
Do you have questions about
@veupathdb.org
's funding status and prospects for the future, or about our newly implemented subscription service? Please take a look at our Frequently Asked Questions for answers to these questions and more!
veupathdb.org/veupathdb/ap...
#fungi
#Parasites
0
2
2
reposted by
ParasitesRule
10 months ago
Did you miss our
@veupathdb.org
OrthoMCL-7 webinar on Tuesday? Not to worry - the recorded webinar is now available for on-demand learning!
#orthology
#data
📹 Check it out here:
www.youtube.com/watch?v=htZq...
0
2
1
reposted by
ParasitesRule
10 months ago
Thanks to all lab heads and group leaders who have filled out and paid invoices for a
@veupathdb.org
subscription! Your contributions keep our data resources open access.
#data
#parasites
#fungi
#vectors
If you haven’t done so already, this is an URGENT need!
veupathdb.org/veupathdb/ap...
0
6
3
reposted by
ParasitesRule
10 months ago
New data alert! 📂ToxoDB now includes data from functional profiling of the entire T. gondii genome during cell culture & murine infection using a CRISPR-based screen (Guiliano et al. 2024). 🔎 Explore the data here
toxodb.org/toxo/app/sea...
2
5
3
It is time to put in your nominations for the prestigous Alice and CC Wang Award in Molecular Parasitology. Nominations must originate from ASBMB members but the nominee need not be a member. Nominations are due by June 4, 2025. @ASBMB 🔗https://www.asbmb.org/career-resources/awards-grants/wang
10 months ago
0
0
0
Load more
feeds!
log in