ParasitesRule
@parasitesrule.org
📤 261
📥 190
📝 25
Profile picture: Toxoplasma image taken by Omar Harb Banner picture: Plasmodium from Volker Heussler
reposted by
ParasitesRule
Jon Boyle
6 days ago
Our work just came out today in print form in Nat Micro. Really a tour de force from Hisham Alrubaye on sexual development in Toxoplasma gondii. Well done!
rdcu.be/feOj6
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A single-cell atlas of Toxoplasma sexual development in the feline intestinal tract
Nature Microbiology - Single-cell RNA sequencing is used to study the sexual development of Toxoplasma gondii in cats, generating a transcriptional atlas and showing that the female-specific gene...
https://rdcu.be/feOj6
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ParasitesRule
Maryse Lebrun
about 1 month ago
Honored and proud to be elected EAM member. Huge thanks to mentors, my amazing team (past&present), the great parasitology community
@parasitesrule.org
@parafrap.bsky.social
for support throughout this journey
@inserm.fr
@cnrs.fr
@umontpellier.bsky.social
@erc.europa.eu
@frm-officiel.bsky.social
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Parasitology is as beautiful as it is complex! 🔬🧬 Share your striking scientific images with the global community. Submit your microscopy, field shots, structure or lab art to the ParasitesRule gallery: 📸 Submit:
forms.gle/DDLJKfkcsMWm...
#Parasitology
#SciArt
#Microscopy
26 days ago
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🌍 Attention LMIC parasitology trainees! Apply for the 2026
#ACMCIP
Travel Award to attend @ASTMH in National Harbor, MD 💰 Up to $2,000 for travel & registration. 🔬 Open to L/LMIC students & early post-docs. 📅 Award Deadline: April 6. Apply here:
tinyurl.com/4eeeckhm
27 days ago
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ParasitesRule
Paul Sigala
28 days ago
Thrilled to share a new collaborative preprint, joint with Sean Prigge
@johnshopkinssph.bsky.social
, on the apicoplast ACP in
#malaria
parasites.
@uofubiochem.bsky.social
@uuhsresearch.bsky.social
@parasitesrule.org
www.biorxiv.org/content/10.6...
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https://www.biorxiv.org/content/10.64898/2026.03.29.713301v1
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ParasitesRule
Paul Sigala
about 2 months ago
Happy to announce a new review article by MD/PhD student Kade Loveridge on iron metabolism in
#malaria
#parasites
.
@uofubiochem.bsky.social
@uuhsresearch.bsky.social
@uofutahcihd.bsky.social
@parasitesrule.org
journals.plos.org/plospathogen...
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Fifty shades of iron: Unorthodox mechanisms of iron acquisition and utilization in blood-stage Plasmodium parasites
Plasmodium falciparum parasites cause severe human malaria and depend on iron for essential metabolic processes during all phases of their complicated lifecycle, including when growing in human red bl...
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1014030#references
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🔬 Featured Image Trypanosoma cruzi amastigotes (red) infecting a cardiomyocyte (cyan) in a mouse heart, with CD4 (green) and CD8 (magenta) T cells revealing the immune response. 📸 Fernando Sanchez-Valdez, @CTEGD, University of Georgia
parasitesrule.com
about 2 months ago
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🚨🚨🚨Game changer for babesia research from the Mamoun lab: Continuous In Vitro Propagation of the Human Pathogen Babesia microti in Human Erythrocytes
@yalemedicine.bsky.social
@yalepress.bsky.social
www.biorxiv.org/content/10.6...
about 2 months ago
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🌍 Calling parasitologists from LMICs! Apply for the MPM XXXVII LMIC Travel Award to attend the Molecular Parasitology Meeting in Woods Hole, MA (September 13–17, 2026). Awards include full registration, travel, and accommodation. 🗓️ Deadline: March 1, 2026 🔗
www.parasitesrule.com/mpm-xxxvii/t...
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Travelaward2026
MPM LMIC award details
https://www.parasitesrule.com/mpm-xxxvii/travelaward2026
2 months ago
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🔬 February image is live! Trypanosoma cruzi trypomastigote inside a host cell, captured using ultrastructure expansion microscopy. 📸 Ramiro Tomasina Institut Pasteur de Montevideo Share your parasite images at parasitesrule! 🔗https://www.parasitesrule.com/
3 months ago
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The deadline to apply to BoP is coming up quickly. Make sure to get your application in by February 5, 2026.
add a skeleton here at some point
3 months ago
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ParasitesRule
Victor Tobiasson
3 months ago
FYI were starting weird structure/evolution/biology stuff at Glasgow University! If you're interested let me know! Tell your friends! CRYO
www.jobs.gla.ac.uk/job/research...
BIOINFO
www.jobs.gla.ac.uk/job/research...
TECHNICIAN
www.jobs.gla.ac.uk/job/technici...
#science
#hiring
#evolution
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ParasitesRule
GadelhaLab
3 months ago
If you assume GPI insertion signals = surface destination, trypanosomes disagree. Tom’s work shows GPI-anchored protein sorting occurs independently of GPI insertion signals, hinting at alternative sorting logic at the parasite surface.
tinyurl.com/gpi-anchor
#MembraneBiology
#CellSurface
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Sorting of GPI-anchored proteins at the trypanosome surface is independent of GPI insertion signals
The segregation of glycosylphosphatidylinositol-anchored proteins (GPI-APs) to distinct domains on the plasma membrane of eukaryotic cells is importan…
https://tinyurl.com/gpi-anchor
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🔬 Our first community-contributed image is here! Stunning SEMs of two Trichomonas vaginalis parasites connected by cytonemes. Want to share your parasite images? Visit
parasitesrule.com
to contribute! 📸 Salas et al., eLife 2023 doi:10.7554/eLife.86067 @eLife
4 months ago
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🦠 Calling all parasitologists! New feature:
parasitesrule.com
showcase YOUR research images on our homepage. Whether it's a beautiful microscopy shot, field work, or lab research - share it with fellow parasitology enthusiasts! Submit here:
forms.gle/b3s8bJbQuTZc...
#Parasitology
#SciencePhotography
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Parasitesrule
Dr. Roland A. Cooper
https://parasitesrule.com
4 months ago
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ParasitesRule
Bloodsucking Parasites
4 months ago
Genetic characterization and identification of a recent discovered genotype of Theileria orientalis (Piroplasmida: Theileriidae) in water buffaloes (Bubalus bubalis) from the Amazon region, Brazil Ticks&TBD
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Genetic characterization and identification of a recent discovered genotype of Theileria orientalis (Piroplasmida: Theileriidae) in water buffaloes (Bubalus bubalis) from the Amazon region, Brazil
Publication date: January 2026 Source: #ticks and #tick-borne Diseases, Volume 17, Issue 1 Author(s): João Paulo S. Alves, Pedro H.C. Rodrigues, Anisleidy P. Castillo, Antônio A. Fonseca Junior, Cairo H.S. de Oliveira, Rômulo C. Leite, José D. Barbosa, Júlia A.G. Silveira
http://dlvr.it/TPsM0G
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ParasitesRule
Uni of Nomi
4 months ago
#Parasitologists
! Partake in this free
#training
offered by and for
#VEuPathDB
- an invaluable platform for -omics data and analytical tools centered around some of the most neglected fields of science!
#parasitology
#mycology
#fungus
#pathogen
#vector
#eukaryote
#protists
add a skeleton here at some point
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🦠 Grad students & postdocs in parasitology: Apply now for the Biology of Parasitism (BoP): Modern Approaches course at @MBLScience. Hands-on labs, expert lectures, and cutting-edge tools. 📅 Summer 2026 | ⏰ Deadline Feb 5 🔗
mbl.edu/courses
4 months ago
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ParasitesRule
Anthony Olszewski
5 months ago
"This interview with Dr. Emma H. Wilson details recent findings on how the chronic parasitic infection Toxoplasma gondii (*Toxo*) disrupts neurotransmission in the rodent brain. The study demonstrates ..."
www.youtube.com/watch?v=l6DP...
#Toxoplasma
#Toxoplasmosis
#Parasite
#Parasitology
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Professor Emma H Wilson discusses Toxoplasma gondii.
YouTube video by Anthony Olszewski
https://www.youtube.com/watch?v=l6DPivZN9Ys
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ParasitesRule
University of Glasgow School of Infection & Immunity
5 months ago
🎥 | WATCH | Dr Thomas Hollin (
@umontpellier.bsky.social
) discusses RNA-binding Proteins and Organellar Gene Regulation in Plasmodium falciparum. The full Centre for Parasitology seminar is now available for a limited period on our YouTube channel: 📺
youtu.be/aH9aZAbJaIs?...
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ParasitesRule
Paul Sigala
6 months ago
Thrilled our study on heme crystal motion in
#malaria
@parasitesrule.org
is now published
@pnas.org
, support from NIH,
@bwfund.bsky.social
,
@uofutahcihd.bsky.social
, UofU 3i. With Fu and Bidone labs
@price.utah.edu
,
@uofubiochem.bsky.social
,
@uofuhealth.bsky.social
www.pnas.org/doi/10.1073/...
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Chemical propulsion of hemozoin crystal motion in malaria parasites | PNAS
Malaria parasites infect red blood cells where they digest host hemoglobin and release free heme inside a lysosome-like organelle called the food v...
https://www.pnas.org/doi/10.1073/pnas.2513845122
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Missed another parasitology webinar? 😩 I built a page to fix that — a community list of free online seminars anyone can add to! 🧫 Find and share virtual parasitology events here:
www.parasitesrule.com/seminars
6 months ago
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reposted by
ParasitesRule
Keith Matthews
6 months ago
We have a 3+ year post doc available in our lab to study trypanosome transmission and virulence. Combined wet lab and bioinformatics expertise preferred. Please apply via the HR link (
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
). Find out more about us in the link below.
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The Matthews Lab | Biology
The Matthews Lab
https://biology.ed.ac.uk/the-matthews-lab
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The parasitesrule site has an archive of abstract books from the Molecular Parasitology Meeting (MPM) & the Kinetoplastid Molecular Cell Biology Meeting (KMCB). The book from the first MPM (1990) is also there! 🔗
parasitesrule.com/archive
7 months ago
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Did you know that you can submit and view parasitology related jobs on the
#parasitesrule
site? Check out the new interface: 🔗https://www.parasitesrule.com/jobs
7 months ago
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Interested in Parasitology conferences in 2026? Look no further, check out the list of upcoming conferences on the parasitesrule website:
www.parasitesrule.com/conferences
7 months ago
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reposted by
ParasitesRule
Uni of Nomi
7 months ago
Why do we care? Because very little information is available for proteins found in
#parasites
, despite parasites causing a third of the total global burden of human
#disease
(!!!)
#MPM2025
@parasitesrule.org
2/2 More about this problem is explained nicely here:
www.sciencedirect.com/science/arti...
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Exploiting structural biology in the fight against parasitic diseases
Despite spectacular advances in structural biology over the past half-century, only approximately 2% of the structures in the Protein Data Bank are fr…
https://www.sciencedirect.com/science/article/abs/pii/S1471492212000153
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reposted by
ParasitesRule
7 months ago
You can explore the full scRNAseq data on the same gene page:
cryptodb.org/cryptodb/app...
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reposted by
ParasitesRule
7 months ago
The
@veupathdb.org
user comments campaign at
#MPM2025
yielded 200 user comments from 66 attendees! Thanks, contributors 💐 For example: a comment on gene cgd5_3570 on CryptoDB pointed out that GGC proteins exhibit male-specific expression according to single-cell RNA seq. Good to know!
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Recordings of the last 5 Keynote talks at the Molecular Parasitology Meeting MPM are available on the parasitesrule Youtube channel - check them out - ❤️ like and subscribe:
www.youtube.com/@Parasitesrule
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Parasitesrule
https://www.youtube.com/@Parasitesrule
7 months ago
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reposted by
ParasitesRule
Uni of Nomi
7 months ago
How? By inhibiting the uptake of metabolically essential amino acids and disrupting the parasite's lifecycle. You can learn more about some of their work here:
pmc.ncbi.nlm.nih.gov/articles/PMC...
#Parasitology
#MPMXXXVI
#MPM2025
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Computational approaches for drug discovery against trypanosomatid-caused diseases
During three decades, only about 20 new drugs have been developed for malaria, tuberculosis and all neglected tropical diseases (NTDs). This critical situation was reached because NTDs represent only ...
https://pmc.ncbi.nlm.nih.gov/articles/PMC10317681/
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ParasitesRule
Uni of Nomi
7 months ago
Highlights from
#MPMXXXVI
: Work by Melisa Sayé et al. explores repurposing benztropine - a Parkinson's disease drug - against infection by Trypanosome cruzi, a
#parasite
causing Chagas disease which affects >7 million people worldwide.
@parasitesrule.org
#MPM2025
#Parasitology
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ParasitesRule
Uni of Nomi
7 months ago
Learn more about some of their work here:
pmc.ncbi.nlm.nih.gov/articles/PMC...
(Although ginger extract is used in this paper^. If anyone can point me towards publications of their studies using thyme extract please do!)
@parasitesrule.org
#MPM2025
#Parasitology
#MPM2025
#botany
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Efficacy of green synthesized silver nanoparticles via ginger rhizome extract against Leishmania major in vitro
Leishmaniasis is a major public health problem that causes by parasite of the genus Leishmania. The pentavalent antimonial compounds that used for treatment are not safe or effective enough. The aim o...
https://pmc.ncbi.nlm.nih.gov/articles/PMC8372886/
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ParasitesRule
Uni of Nomi
7 months ago
Highlights from
#MPMXXXVI
: Work by Atena Hesami et al. shows the efficacy of thyme extract incorporated into silver
#nanoparticles
for use against Leishmania major - a
#parasite
causing flesh-eating disease - showing the value of naturally sourced compounds as augmentative antiparasitic agents. 1/2
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ParasitesRule
Uni of Nomi
7 months ago
Highlights from
#MPMXXXVI
:
#Ticks
! (woot!) Work by Isaac A. Hinne et al. identified stage-specific gene expression profiles in developing
#tick
embryos (Ixodes scapularis). Targeting embryonic development in ticks offers a unique point of
#vector
control.
@parasitesrule.org
#MPM2025
#Parasitology
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ParasitesRule
Uni of Nomi
7 months ago
Hey,
#MPMXXXVI
attendees! Just a reminder today is the last day to vote for your favourite talks and posters from this year's meeting. I've highlighted a few in my posts below!
@parasitesrule.org
#MPM2025
#Parasitology
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ParasitesRule
Henrico Langeveld
7 months ago
Honoured & grateful to have received an MPM Travel Grant and have the opportunity to present my PhD research at my first MPM 🇺🇸 Amazing science, inspiring discussions & a fantastic community of parasitologists – what a milestone in my journey.
@parasitesrule.org
#MPM2025
#Parasitology
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ParasitesRule
Rohit Satyam
7 months ago
Join me on 16 Sept 8-9 AM (Boston time Zone i.e. 3 PM KSA) as I present my R package on how to access VEuPathDB component databases and several other database virtually in MPM XXXVI conference.
rohit-satyam.github.io/plasmoRUtils...
#plasmodium
#pathogen
@veupathdb.org
@parasitesrule.org
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Did you submit an abstract to
#mpm2025
? Notifications went out this week. Check you spam folders if you don't see an email in your inbox.
@rmc9z.bsky.social
@mjgubbels.bsky.social
@omarharb.org
9 months ago
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reposted by
ParasitesRule
11 months ago
🚀Big News! We’re now offering AI-powered summaries of expression data on gene pages in
@veupathdb.org
See expression patterns and get insights with a single click! 🧬🔎 Go to your favorite gene pages and look for “AI Expression Summary” under Transcriptomics.
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ParasitesRule
Geoff McFadden
11 months ago
We are developing a simple, very cheap, low tech way to reduce malaria transmission. Instead of giving the antimalarials to people, we give them to the mosquitoes that spread the parasite. How do we drug a mosquito? Read on.
www.sciencedirect.com/science/arti...
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Identifying antimalarials that disrupt malaria parasite transmission when fed to the mosquito
A decade-long decline in malaria cases has plateaued, primarily due to parasite drug resistance and mosquito resistance to insecticides used in bed ne…
https://www.sciencedirect.com/science/article/pii/S0020751925000967?CMX_ID=&SIS_ID=&dgcid=STMJ_220042_AUTH_SERV_PA&utm_acid=96694420&utm_campaign=STMJ_220042_AUTH_SERV_PA&utm_in=DM572707&utm_medium=email&utm_source=AC_#f0025
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reposted by
ParasitesRule
Bloodsucking Parasites
11 months ago
Three Hungry Tryps: the efficient endocytic pathway of pathogenic trypanosomatids Trends_Parasitol
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Three Hungry Tryps: the efficient endocytic pathway of pathogenic trypanosomatids
Eukaryotic cells incorporate various molecules through a process known as endocytosis, which is crucial for the cell's survival and reproduction. While this process has been extensively studied in mammalian and yeast cells, significant contributions have also been made by researchers studying pathogenic protists. This review aims to present the most relevant information about the endocytic process in three important trypanosomatids: Trypanosoma cruzi, Trypanosoma brucei, and Leishmania. Many protozoa exhibit strong endocytic activity across their entire surface. However, in trypanosomatids, this activity is highly polarized and occurs exclusively in the flagellar pocket. In the case of T. cruzi, endocytosis primarily takes place through the cytostome–cytopharynx complex. This process involves an entry site organization of the cytoskeleton, including the participation of specialized microtubules.
http://dlvr.it/TLDqx7
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Registration and Abstract submission for MPMXXXVI are now open! Abstract submission deadline is June 27th, get yours in quickly.
@rmc9z.bsky.social
@mjgubbels.bsky.social
@omarharb.org
🔗https://www.parasitesrule.com/mpm-xxxvi
11 months ago
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reposted by
ParasitesRule
11 months ago
Make open access to tools and data part of your annual giving by making a tax deductible donation to
@veupathdb.org
. 💙This resource simplifies and supercharges global infectious disease research. Need more reasons to support VEuPathDB? Here's a short list:
veupathdb.org/veupathdb/ap...
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reposted by
ParasitesRule
11 months ago
Today, we're highlighting a section of the gene page in
@veupathdb.org
data platforms that allows you to use RNA seq evidence to 🔎🧬examine gene models- making it easy to spot splice variants or incorrect annotation. Take a look!
www.youtube.com/shorts/T0Jis...
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Intron spanning reads and gene models
YouTube video by VEuPathDB
https://www.youtube.com/shorts/T0JisZ8aRjw
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reposted by
ParasitesRule
11 months ago
Today's short video features the proteomics section of our encyclopedic gene pages. 🧬 Quickly find mass spec evidence, post-translational mods, and more for your favorite gene in
@veupathdb.org
and all of our component databases. Watch it now!
www.youtube.com/shorts/o0s-D...
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Proteomics data on gene pages
YouTube video by VEuPathDB
https://www.youtube.com/shorts/o0s-DwUbVnQ
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ParasitesRule
Author Bill Sullivan
11 months ago
A common parasite can decapitate human sperm − with implications for male fertility
theconversation.com/a-common-par...
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A common parasite can decapitate human sperm − with implications for male fertility
If you’ve handled cat litter or eaten raw meat or unwashed produce, there’s a chance you might have a permanent toxoplasmosis infection spread throughout your body.
https://theconversation.com/a-common-parasite-can-decapitate-human-sperm-with-implications-for-male-fertility-256892
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reposted by
ParasitesRule
11 months ago
📹We've made more short videos to highlight features on
@veupathdb.org
💫 This one walks you thro' the section on gene pages called the RNAseq transcriptomic summary. Get an overview of datasets where your favorite gene is doing something interesting. Watch it now!
www.youtube.com/shorts/V2eZi...
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Gene Page RNAseq Transcriptomic Summary
YouTube video by VEuPathDB
https://www.youtube.com/shorts/V2eZiwFFoJA
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ParasitesRule
Faria Tryps Lab
11 months ago
So happy to share the first preprint from our lab on post-transcriptional regulation at the VSG expression-site body in trypanosomes.
@ybri-uoy.bsky.social
@york.ac.uk
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Specialised RNA decay fine-tunes monogenic antigen expression in African trypanosomes
Antigenic variation is a sophisticated immune evasion strategy employed by many pathogens. Trypanosoma brucei expresses a single Variant-Surface-Glycoprotein (VSG) from a large genetic repertoire, whi...
https://www.biorxiv.org/content/10.1101/2025.05.24.654301v1
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ParasitesRule
Faria Tryps Lab
11 months ago
We identified 3 novel proteins at the ESB that negatively regulate genes co-transcribed with the active-VSG through specialised and spatially regulated RNA decay.
#RNA
#condensates
#3Dgenome
#RNAdecay
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