🙏 @inserm.fr de promouvoir nos travaux récemment publiés dans EMBO Mol. Med doi.org/10.1038/s443... www.inserm.fr/actualite/to...

Zeus had his Hydra ⚔️, now Toxoplasma has its own. Meet Hydra: not a monster, but a brand-new protein domain. It multimerizes like crazy & rewrites the chromatin landscape 🧬 in Toxoplasma. Our team and colleagues from @embl.org #Grenoble just dropped the preprint 👉 www.biorxiv.org/content/10.1...

Thrilled to share our latest review! 🎉 It captures the ideas and discussions that have shaped our work in recent years. Big shoutout to the amazing authors 👏 @hakimi.bsky.social www.sciencedirect.com/science/arti...

Toxoplasma facing career options: 🏃 Tachyzoite (fast life) 😴 Bradyzoite (chronic sleeper) 🙀 Pre-sexual (cat-ready) Spoiler: epigenetics makes the call. Our recent review in Current Opinion in Microbiology decodes how chromatin remodelers, TFs& AP2s orchestrate these fates 👇🏽 doi.org/10.1016/j.mi...

Our July issue is online 👉 www.embopress.org/toc/17574684... The cover highlights the article by M Robert, C Swale, MP Brenier-Pinchart, @hakimi.bsky.social‬ & al. that identifies BSM & BCLA as #biomarkers for chronic #ToxoplasmaGondii infection Scientific image by @hakimi.bsky.social @inserm.fr

Thrilled to see our work featured on the cover of @embomolmed.org 🎉We identify new biomarkers to track chronic toxoplasmosis—paving the way for improved diagnosis and patient care. doi.org/10.1038/s443... It’s time to bring such tools to the clinic—let’s encourage biotech to take it from here.

Huge congrats @belenpachano.bsky.social on your PhD! Honored to have shared the journey. Your brilliance shines through your articles — past and future. You’ll be missed, but my lab will always be your home. Come back anytime. You’ve earned every success!

I hear you, brother. Loud and clear. Your courage speaks volumes. Standing strong with you—and with Palestine. You're not alone.

🙏🏽the editors, and the reviewers for their warm reception of our manuscript. @embomolmed.org is clearly an excellent journal to highlight—especially to the industrial sector—the importance of incorporating these markers into the portfolio of toxoplasmosis detection tests.

🧵 Ever wondered what Toxoplasma is doing in your brain years after that undercooked steak 🥩 or a sip of contaminated water? Turns out, it's been hiding in your brain 🧠and we finally have a way to spot it. New study just dropped in EMBO Molecular Medicine 👇 doi.org/10.1038/s443...

“In the meantime, the world’s richest man (Musk) has been involved in the deaths of the world’s poorest children” www.theguardian.com/us-news/2025...

An ISWI-related chromatin remodeller regulates stage-specific gene expression in #Toxoplasma gondii. By Belen Pachano (ParaFrap PhD student) et al., team @hakimi.bsky.social. In @natmicrobiol.nature.com www.nature.com/articles/s41...

🚨 Out now! Toxoplasma gondii ISWI remodeller TgSNF2h forms a complex that insulates active genes, regulates MORC-driven sexual commitment and ensures precise gene expression, safeguarding the parasite’s developmental program. #MicroSky 🦠 www.nature.com/articles/s41...

In the silence of chromatin, Toxoplasma whispers change. TgSNF2h sculpts the genome - MORC in the backseat. Some genes wake. Others sleep. A dance of nucleosomes shaping space for life parasite stages to unfold. Now in Nature Microbiology: rdcu.be/ehkWp

Thrilled to share my first paper, now out in @natmicrobiol.nature.com! Huge thanks to my amazing supervisor @hakimi.bsky.social and everyone who contributed to this work! www.nature.com/articles/s41...

A humorous reflection on the first article from my stellar PhD student, Belen Pachano. communities.springernature.com/posts/open-s...

In the silence of chromatin, Toxoplasma whispers change. TgSNF2h sculpts the genome - MORC in the backseat. Some genes wake. Others sleep. A dance of nucleosomes shaping space for life parasite stages to unfold. Now in Nature Microbiology: rdcu.be/ehkWp

@inserm.fr presse.inserm.fr/cest-dans-la... Science must not be damaged, as it takes too long to repair.

Huge congrats to colleagues & friends for uncovering PfSnf2L, the chromatin remodeler that Plasmodium relies on to shape its gene expression. A new inhibitor wrecks the blueprint, blocking parasite growth & transmission. Next up: Toxoplasma SNF2L/h—stay tuned! t.co/IqO4O3tWQX

Thrilled to announce the creation of the @elisabethbik.bsky.social Science Integrity Fund to provide "funding for training programs, grants, or awards for science integrity advocates." Thanks to @science.org for covering this. Help us grow the fund with a tax-deductible donation.

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Solving 25 years of frustration, Daniel Abbühl managed to tag trypanosome tubulin and to express it in an inducible manner, hence revealing flagellum assembly! A tour-de-force! Preprint here: www.biorxiv.org/content/10.1...

Fungus fight just leveled up! @jeromegovin.bsky.social and coll. found a new way to take down drug-resistant Candida by targeting the Bdf1 bromodomain. 🦠🔥👏 Bravo for this epic study using epi-drugs !

Bravo to the authors for this tour de force 🥳👏🏽

Our assessment of a person's epigenetic ("biological") age has been centered on DNA methylation. A new report shows that a set of 7 histone markers has comparable accuracy and also uncovers new pathways of aging biology www.science.org/doi/10.1126/...

Cuba’s Center for Genetic Engineering and Biotechnology has continued to shepherd the development of drugs and vaccines for cancer, infectious disease and other conditions and to date has obtained regulatory approvals in more than 50 countries go.nature.com/4gxkhYt rdcu.be/d4Z0N

👌🏽 perfect way to end 2024 👏🏽

1/ We are excited to share our new paper in @jexpmed.bsky.social about humans with autosomal dominant IFNAR1 deficiency (doi.org/10.1084/jem....).

what a 'tour de force' ! 👏🏽👏🏽 to the authors !

Malaria – the world’s most deadly vector-borne disease – is particularly sensitive to variations in climate and weather. (...) Investment in climate-resilient health systems and paradigm-shifting new tools is critical to accelerate progress towards eradication. malariaatlas.org/project-reso...

Please join us Friday 12th at noon EST for Dr. @zamanian.bsky.social seminar at Parasite hour with #PeersInParasitology where he will share his recent work on new targets and strategies for helminth control. Need a zoom link? Register here: iu.zoom.us/webinar/regi....

We've been awarded a UKRI MRC grant to examine the causes and consequences of #heterochromatin hypomethylation in cancer 🥳. #postdoc opportunity coming in the near future. #epigenetics. Please share with anyone who might be interested.

Great mentees make a proud PI.😊

Apicomplexan parasites (#Toxoplasma #Plasmodium) showcase remarkable phenotypic plasticity and a compact genome. MORC might be the maestro, topologically orchestrating gene expression! 🎻

Please RS/RT. #GordonConference on "Histone and DNA Modifications" #epigenetics #chromatin 20-25. July 2025. Il Ciocco, Italy. Great speaker lineup. ➡️Register now www.grc.org/histone-and-...

Real (Time) Tango of Transcription and Translation. 👏🏽👏🏽👏🏽 to Nusrat Shahin Qureshi & Olivier Duss 👇🏽

A new 'crypto' story where the authors KO every single human gene to uncover #Cryptosporidium 's survival secrets. Dive into the preprint for the inside scoop ! 👏🏽👏🏽👏🏽Bravo to Bishara and colleagues for this new Opus from @saterialelab.bsky.social team. 👇🏽

Here comes the SUN1! ☀️ A bright discovery in parasite cell division! 👏🏽👏🏽👏🏽👇🏽

Exciting news! 🇫🇷 network ParaFrap is now on Bluesky! Calling all parasitologists (and beyond) to join us at 👉 @parafrap.bsky.social Let’s connect and share! 🦠 #Parasitology

From my office window, a stunning sight: blue sky and snow-dusted mountains, the first of the season. #Grenoble

Okay Bluesky people- there is now an account here for the British Society for Parasitology (BSP) at @bspparasitology.bsky.social!! BSP also has a Facebook group, LinkedIn (private group), X (for the moment), and a webpage at bsp.uk.net/Home! We have so many updates to come- #BSP2025 is coming! 🦠

👏🏽 @thibautbrunet.bsky.social

The 2nd edition of the Paris-Munich Epigenetics meeting will be held April 9-11, 2025 in Paris. Attendance is free of charge. Please visit the website www.sfb1064.med.uni-muenchen.de/paris_munich... to find out more about the program and to register. #epigenetics

🚨New COMMENT in Nature Microbiology: Microbial solutions must be deployed against climate catastrophe🚨 @gilbertjacka.bsky.social www.nature.com/articles/s41...