Sawhney et al. followed 52 infants from birth to age 8, uncovering how gut microbiomes shift, stabilize, and evolve. A key finding: the emergence and timing of Bacteroides- and Prevotella-dominated enterotypes. 👶🧬 1/n

🔥New Night Science paper!! Discovery happens when your initial plans fall apart but it requires you to have a particular mindset: it's not extraverted, orderly, neurotic or agreeable that's the most important – discovery requires an OPENNESS to new ideas and unexpected insights.

Not microbiome, but not less interesting: Cousins et al. introduce cobraa, a model revealing that all modern humans descend from two ancestral populations that split ~1.5 million years ago and later admixed ~300,000 years ago. This 80:20% ancestry mix challenges the idea of a panmictic origin 🌍🧬 1/n

Big news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers] openrxiv.org 1/n

👇Four days left to apply! (Friday 14th of March)👇

Excited to share our latest work on the gut microbiome in inflammatory bowel disease patients. This is the result of hard work across generations of trainees in the Donia Lab, in collaboration with amazing scientists (Nobuhiko Kamada and Lea Ann Chen). www.cell.com/cell-host-mi...

Tian et al. designed a synthetic microbiota that suppresses C. difficile infection. Using machine learning, they built a 37-strain synthetic fecal transplant (sFMT1) that successfully inhibited C. difficile in vitro and in animal models. 🦠🛠️ 1/n

Lab mice (domesticated for >100y) have kept gut bacterial strains that codiversified w/ rodents for >25My. Here, authors show genetic drift occured in the lab, leading to loss of microb diversity+more deleterious mutations, impacting microbial fitness in lab vs wt mice www.nature.com/articles/s41...

I proudly present a new review paper of my group that just came out in Trends in Microbiology @cp-trendsmicrobiol.bsky.social with Leonardo Ona and Shryli Shreekar Disentangling microbial interaction networks Open access link: authors.elsevier.com/sd/article/S...

Coming from a GWAS-lab, my research interest for IBD and host-microbe interactions started here: In this classic paper from 2012, Jostins et al. analyzed 75k+ individuals, identifying new IBD-associated genetic loci, many of which reveal deep evolutionary and microbial connections 🦠📊 1/n

Abdill et al. (@richabdill.com; @blekhman.bsky.social) from the University of Chicago compiled and analyzed 168,000 publicly available human gut microbiome samples to reveal global variation in microbiome composition. 🌎🦠 1/n

Diener @cdiener.com and colleagues from the Institute for Systems Biology (@isbscience.org) and @medunigraz.at introduce MEDI (Metagenomic Estimation of Dietary Intake), a novel method to quantify dietary intake by analyzing food-derived DNA in stool samples. 🧬🥗 1/n

(unsuccessfully) tried to use ChatGPT for scheduling the internal group talks for the next months giving it a few uncomplicated constraints. at least the naming is somewhat human-like...

The gut microbiome isn’t just a collection of species—it’s a network of evolving subspecies. Doran et al. from the University of Chicago introduce the Spectral Tree, a new way to map these hidden evolutionary relationships. 🌱🧬 1/n

Since beginning of last year, I am a #NewPI within the @dfg.de-funded Collaborative Research Center 1182 "Origin and Function of Metaorganisms", which now also made it's way to Bluesky. Welcome, @crc1182.bsky.social! #MicroSky #SciSky

We're hiring a postdoc!🚨 Study human-associated microbial communities in health & disease. 🔬Requirements: - PhD in bioinformatics, microbiology, or related field - Expertise in omics - Strong publication record Apply now!🌟 jobs.vib.be/j/69697/post... @vibmicrobes.bsky.social

Setting new boundaries of 16S rRNA gene identity for prokaryotic taxonomy www.biorxiv.org/content/10.1... #jcampubs

Auschwitz was at the end of a long process. It did not start from gas chambers. This hatred was gradually developed by humans. From ideas, words, stereotypes & prejudice through legal exclusion, dehumanization & escalating violence... to systematic and industrial murder. Auschwitz took time.

To mark #InternationalHolocaustRemembranceDay, you can help build the world’s largest digital memorial to the victims and survivors of Nazism. We want to digitize 27,000 prisoner registration cards from Auschwitz & other concentration camps. Join in and help! everynamecounts.arolsen-archives.org/en/

Combining 168k gut microbiome samples into a single analysis - what a great and important effort. Congrats!

We are looking for 2 #postdoctoral fellows on #gutmicrobiota, #diet and the #gut mucosal barrier in #health and #disease! Details & Application: umustipendie.varbi.com/en/what:job/... Please share!! #postdoc #postdocjob #academicjobs #MicroSky #GISky #Microbiome #MicroSky #AcademicSky #PhdSky

Hey #HiSciSky 👋. I'm a post-doc researcher with a background in scientific device dev. I have just released an open-source STEM-Education project for a $40, 3D-printed, DNA fluorometer with ng/uL levels of sensitivity. Follow for updates! GitHub Repo: github.com/traulab/DIYN... #DIYNAFLUOR #STEM

End-of-the-year-vibes with little sleep and lots of things to be done. www.youtube.com/watch?v=wNfK...

1/3 🌍 We're hiring! The Medical Systems Biology Lab at Kiel University is looking for a passionate #PostDoc in #Metabolic #Microbiome #Modeling. Join us at one of Europe’s microbiome research hubs and push the boundaries of microbiome science! @kieluni @UKSH_KI_HL 🔗 jobs.uksh.de/job/Kiel-Pos...

Returning after a first month of parental leave, I am thrilled to see many reasearchers moving to this place. A good timepoint to re-introduce myself: I am a PostDoc at @mmmicrobiomelab.bsky.social interested in how the human microbiome is shaped by lifestyle, disease, genetics and evolution.

Our paper together with @typaslab.bsky.social is out now! doi.org/10.1016/j.ce... Previously available on bioRxiv, it has now been accepted in Cell. 🎉 @sarsarela.bsky.social and @biocs.bsky.social show that bacteria can be protected from & sensitized to drugs in community; ... (1/2)

Bioinformatics, but the other way around 🤯

For the first time in the role of project PI, I presented our planned work and early results as part of the @dfgpublic.bsky.social|-funded #CRC1182. I have been part of the consortium as PhD candidate and PostDoc and I'm happy to continue and expand this work now with my 'own' project!

Celebrating 10 years at IKMB Kiel this month. DALL-E generated a nice image for the occasion!

“Togetherland” — diversity makes us strong. Hollow populism? No thanks! “Remigration”? Absolutely not. Fascism? Never again. We have learned from history. Newspaper ad by German universities and non-university research organizations such as @maxplanck.bsky.social

I've never been a fan of #MDPI, but needing to sign up for an account to receive the reviewer comments of a rejected manuscript I co-authored also really doesn't make things any better

Welcome to #bluesky, Groussin & Poyet lab @mmmicrobiomelab.bsky.social ! Follow for exciting microbiome science 🦠, updates from the lab and the Global Microbiome Conservancy! #MicroSky #Science

Seeing the BASALT bin refiner out in Nat Comms, I just want to advertise our bin-refinement tool "MAGScoT" again: github.com/ikmb/MAGScoT MAGScoT is fast, easy to use and ressource friendly, outperforming DASTool and metaWRAP. Comparison to BASALT not easy, as no intermediate files are provided.

Looking for a postdoc in Europe? Check out the KiTE fellowships at Kiel University. 67-75K (Euro) salary and you would get to work with some great faculty (including the amazing Mathieu Groussin and Mathilde Poyet). Learn more here: www.uni-kiel.de/en/research/...

Our latest preprint is @cdiener.com's magnum opus. Basically, it's a method for inferring dietary and nutritional intake from food-related DNA present in human stool. Metagenomic Estimation of Dietary Intake (MEDI) 💩🧬▶️🌽🍊🥩🍤 t.co/8rlfzBU52U

German coffee culture in a nutshell

Through homology search & pLMs, we identified an effective kynureninase that degrades a key immunosuppressor in cancer, reducing tumor weight in mice by 3.4x. 📄 www.biorxiv.org/content/10.1... Seek & rank your own protein based on only a handful of measures. ⛵ seekrank.steineggerlab.com

Community-scale models of microbiomes: Articulating metabolic modelling and metagenome sequencing Microbial Biotechnol review from Clémence Frioux ami-journals.onlinelibrary.wiley.com/doi/full/10....

Happy to offer 2 PhD positions on sponge-microbe interactions (deadline Feb 16th, 2024) that are funded within the CRC 1182 Origin and Function of Metaorganisms. The link is now live: www.geomar.de/en/karriere/... www.metaorganism-research.com/about/

Happy new year! And I'm glad to start it off with good news, our article 'Functional host-specific adaptation of the intestinal microbiome in hominids' has been published over the weekend in Nature Communications #microsky

We recently uploaded a pre-print on the gut microbiota in inflammatory bowel disease performing meta-analysis across cohorts from Germany, Sweden and the US

A reminder for ECRs who are looking for an opportunity to form their own group to study contemporary questions in marine sciences in Germany with 5-years of support: hifmb.de/focus-group-...

...and more great news recently: the CRC1182 Origin and Function of Metaorganisms was renewed for a third funding phase and I will be part of it as a PI. Looking forward to the next four years of metaorganism science!

Very happy having been chosen to receive the Bruhn Foundation award for the promotion of early career researchers 🍾 www.uni-kiel.de/de/detailans...

Excited to share our new technique for studying IgA binding in the microbiome! Fascinated by IgA since joining the Sonnenburg Lab, this work beautifully leverages Dr. Sean Spencers's immunology & my metagenomics expertise to make fundamental discoveries about IgA in the gut doi.org/10.1101/2023...

I now left twitter for good. Hoping to see many more scientists move over to this site!

Last day of Horizons in Metaorganism Research. The weather in Kiel doesn't keep up with the quality of the science.

And today in #ClosedAcess irony

Conferencing with a view. Horizons in Metaorganism Research hosted by the CRC1182 (metaorganism-research.com)

Interesting and important paper by Petra Bacher and her team at IKMB Kiel on the role of yeasts as drivers of aberrant CD4+ T cell reactivity in patients with Crohn's Disease www.nature.com/articles/s41...