I am excited to announce that we have two open positions on our recently funded MYBstery M-WEAVE (NWO-DFG) project! 1) Postdoc in my team at Utrecht University (NL). www.uu.nl/en/organisat... 2) PhD in the team of @lauraragni.bsky.social at University of Freiburg (DE). (See thread)

FridayNight coding; a #ggplot2 extension that drops the boxplot when n is too low

"genAI can be used to create podcasts from a paper to teach st-" Let me stop you right there. Before you feed somebody's paper to a slop machine, invite that somebody to talk to your students about their paper. We're right here. We academics won't shut up about our work, man. 🧪

@synbio1.bsky.social is cooking again youtu.be/nHJKpC2GUsw?...

My in-terminal plasmid editor is ***actually*** coming together! Next big feature is a proper synbio module editor. Check back often; actively developing this! github.com/Binomica-Lab...

Thank you, @asimovpress.bsky.social open.substack.com/pub/cell/p/p...

🧬 Please repost 🧬 I was asked to organise a panel discussion for a SynBio Student Meetup in Hamburg in the middle of May and I'm still looking for panellist! If you know any researchers at the PhD/Postdoc who have expertise in metabolic/genome/multicellular organism engineering, please reach out!

New method paper from Alberto Caregnato and former PhD student @hohmannulrich.bsky.social. A tailored crystallisation screen for plant receptor kinase ectodomains, with examples from our lab and from @cellsensing.bsky.social. Check it out: www.biorxiv.org/content/10.6...

Scientific conferences can be a bore. Can jokes liven them up? Science Careers speaks with ecologist @stefanomammola.bsky.social about the power of humor to enhance science communication. https://scim.ag/4uCVf1N

Spectral multiplexing is typically limited to 4-5 channels. Our new preprint introduces a framework that utilizes DNA barcoding and signal tuning to enable robust spectral unmixing and ground-truth benchmarking to achieve 15-plex subcellular profiling without cycling www.biorxiv.org/content/10.6...

Would I have called it reverse translation? No. Do I think it is? Also no. Is it cool? Heck yes. www.nature.com/articles/s41...

Cool new preprint on cell wall charge and iron by @elkebarbez.bsky.social . Congrats to all involved.

🦖 The Plasmidsaurus Merch Store is officially OPEN! To celebrate, we’re launching Merch Madness, a 3-week tournament of challenges to win mystery merch. Round 1: In 5 words or emojis only, tell us: What are you currently sequencing? 🧬👇 🛒 Plus, grab your favorite gear: merch.plasmidsaurus.com

The 7th International Symposium on Plant Apoplastic Diffusion Barriers (PADiBa2026) will be held in Lausanne, Switzerland from August 31th to September 3rd 2026. We now have a website: wp.unil.ch/padiba2026/ Registrations will open on April 1st.

Is #AI hitting a plateau in structure prediction? Help us find out at CASP17! 🧪🧬 Calling for Targets: Immune Complexes, protein - ligand complexes, RNA/DNA, conformational ensembles, membrane proteins, viral origins, and large complexes. The Rule of Thumb: If AF3 can’t model it, we want it.

More lies from George Church's company. They cannot do what they claim. Perhaps not surprising from a scientist whose work was funded by Jeffrey Epstein www.theguardian.com/us-news/2026...

New Article! Quantitative imaging of apoplastic pH in plant roots via confocal microscopy

Something exciting for student across Africa. @Synbio4allA (SynBio4ALL) Lil Lab Innovation Program Micro-Grant 2026 is coming. • $50 micro-grant • Mentorship • Chance for a $100 follow-up grant 6 student teams from Africa. Applications opening soon Follow SynBio4ALL Africa.

Two papers on apoplastic pH visualisation coming out together – a nice double pack from @aroessling.bsky.social and @elkebarbez.bsky.social -> www.nature.com/articles/s41... -> link.springer.com/article/10.1... @dompsfr.bsky.social @biologyunifreiburg.bsky.social @cibss.bsky.social

Want to image apoplastic pH in plants? 🔬 Two new papers from our team offer a full workflow plus open access analysis tools. Congrats to @aroessling.bsky.social, Niklas Mayle and @lguerard.bsky.social Nature Protocols: rdcu.be/e7R2E BMC Methods: lnkd.in/dctpWJ3X Happy Imaging!

If you have the opportunity, apply for the TSL @thesainsburylab.bsky.social Summer Conference. An intense week with top experts in plant-microbe interactions. What you can learn here in a week would normally take months (or longer)!!! @kamounlab.bsky.social 🦠🔬🌱 www.tsl.ac.uk/tsl-summer-c...

Kilian is just crazy... www.youtube.com/watch?v=CTlk...

#Chemchat, take a look at this.

An Ultraresponsive Green Biosensor for Robust in Vivo Imaging of Synaptic Zinc Dynamics pubs.acs.org/doi/full/10....

The science is as over-hyped and borderline fraudulent as the ethics are thorny (and that doesn't even count the George Church, friend of Epstein angle)

🧬 Just pushed new updates to #OpenCloning Assembler based on user feedback! ✍️ Now supports #GoldenBraid and Plant #MoClo 🚀 You can edit assembly product names, view a full syntax overview, and enjoy cleaner visuals. 👉 Try it out (link in comments) — feedback welcome!

Since people are liking the Bocchi colors, I have a whole collection of color palettes on my GitHub: github.com/cxli233/Colo... You will find the hex code, the preview, and the inspiration for each color palette. I hope some of them will be used. #DataVis

The OpenPlant kit is finally available from Addgene as... a kit :) www.addgene.org/kits/haselof... @addgene.bsky.social #marchantia #synbio

“...the old conferences did not care about diversity. I suggest you not either,” Epstein wrote to Brockman. “The women are all weak, and a distraction sorry.” 😡👩🏻‍🔬 #AcademicSky

New Ed Yong book in April 2027 let's gooooo

We teamed up with OpenFlower (@nickdesnoyer.bsky.social), a nonprofit creating designer flowers for art & education, to release 3 limited edition postcards! These flowers were powered by Whole Plasmid Sequencing from Plasmidsaurus. Want one? Just fill out the form! tinyurl.com/plasmidsauru...

🚀 Excited to launch the #OpenCloning Assembler! 🧬 Built to demystify Golden Gate for beginners and save time for experts -> MoClo assembly blazing fast ⚡ ✍️ Use existing syntaxes or design your own! #SynBio #GoldenGate #MoClo #OpenSource #Biotech 👉 Try it: app.opencloning.org Feedback welcome!

Our work now on its final version. We mapped the mechanical properties of roots at tissue and single cell levels using Brillouin microscopy and molecular rotors. Additional mutants and stress measurements from what we previously showed in the preprint are included. www.science.org/doi/10.1126/...

DeepL seems to have updated and has removed the "thesaurus" feature. Does anybody know a good alternative to DeepL?

Interesting paper: Metabolic enzyme PAL can go into the nucleus in response to high product build up and sequester an activating TF of the pathway, thus acting as a feedback inhibition loop. From: www.science.org/doi/full/10.... #PlantScience

Very nice genetic dissection of the roles of BSK kinases in brassinosteroid signaling by Wenqiang Tang's lab. bsk-u (ko for BSK1 1, 2, 3, 4, 5, 6, 7, 8, 10, 11 & 12) really looks like a bri1 null mutant and can be rescued by over-expressing BSK3. nph.onlinelibrary.wiley.com/doi/epdf/10....

And save >80% on the cost by pooling 6 or more plasmids into a single sample using our free SAVEMONEY algorithm! elifesciences.org/articles/88794 colab.research.google.com/github/Masaa...

Transcription terminators can be strong promoters https://www.biorxiv.org/content/10.64898/2026.02.12.705533v1

Does anybody have access to this article? link.springer.com/article/10.1...

does anyone know what kind of beetle this is? inaturalist is just suggesting some kind of scarab. I saw it in the adirondacks by tupper lake in july

Why hasn't this paper gotten more attention?

🔵mTurquoise2-based glucose biosensors TINGL and THINGL from @joachimgoedhart.bsky.social and the Teusink Lab! Find the plasmids here: www.addgene.org/browse/artic...

PhD opening Join a collaborative, interdisciplinary project the Excellence Cluster Future Forests @uni-freiburg.de, working on CRISPR/Cas in poplar to understand how trees cope with climate stress. Apply here: uni-freiburg.de/en/job/00004... @dompsfr.bsky.social @biologyunifreiburg.bsky.social

We're recruiting a PhD student to try and understand stress memory and gene function, using gene editing, in trees! #plantscience

OpenAI fired a VP who opposed their erotica rollout (and had started a company-wide peer mentorship program for women), allegedly telling her it was because she discriminated against a man 🤔 www.wsj.com/tech/ai/open...

Why do some scientists say "Bluesky is dead. I have no engagement. I have more engagement on X"? My TL is full of cool science, queer art, weird history facts, politics and whimsy. You're just not doing it right, man. Plus the fascism

Anyone ever tried super glue (cyanoacrylate) for mounting coverslips with stained mammalian cells, to be used for fluorescence microscopy? I'm looking for ways to conserve microscopy samples for a looooooong time...