New: Trump admin moves to pull supercomputing center out of top weather and climate research center (NCAR) in Boulder, Colo. Part of its effort to "break up" the lab. www.cnn.com/2026/02/13/w...

RNA comes close to copying itself | Science www.science.org/doi/10.1126/...

So, so, honored by this award—it is daunting to know that my heroes have won this award! Thanks to my heroes and mentors, and my trainees, who are everything!!!!

it looks as shiny and wonderful as the day you made it!

another stunning piece by the amazing and uninimitable @bryanwelm.bsky.social . I would recognize his pieces anywhere!

No, DeepMind has not solved the protein folding problem. #Alphafold predictions are valuable hypotheses and accelerate but do not replace experimental structure determination.

Work hard — play hard 💪🧬🧫

Right now, the Government is starving medical research of full funding, even as it claims that science and research are national priorities. If our leaders truly value science as much as they say, then they must back their words with action—and fund it properly. Join the campaign!

Raven-Flóki & Eric the Red have a lot to answer regarding naming Iceland and Greenland, respectively. However, I don't they could have counted on the Chief of Vineland (Leif Eriksson's name for America) to mix them repeatedly up even if not drunk.

His work laid the foundation for quantum dot technology now used in solar panels, television screens and medical imaging.

The title of this paper is "Specificity of the stabilizing interaction between intrinsically disordered protein sequences and G-quadruplexes in RNA". We show a minimal RGG-rich peptide selectively (compared to other G-quads) stabilizes the structure of the human telomeric TERRA RNA G-quadruplex.

If you have cartoonists on your mind today, read this letter Charles Schulz wrote in 1970: "I believe that our greatest strength lies always in the protection of our smallest minorities." www.kqed.org/arts/1385272...

Powerful piece in STAT this morning from some NIH staff members who have resigned www.statnews.com/2026/01/10/n... 1/3

NIH staffers protest "an organization that has lost its integrity" www.statnews.com/2026/01/10/n...

Some people think science is just for nerds, but science is the foundation of the modern world and science is what made America great. Even though many of us don’t work directly in space science, we were inspired to become scientists by NASA. Destroying it makes zero sense.

If Martin Kettle would have read the great book Humankind by @rutgerbregman.com, this story would not have come as a surprise. Anyway, it is good he realises that journalists, including himself, are partially to blame for our skewed understanding of society. www.theguardian.com/commentisfre...

A new #ScienceAdvances study shows that commercial whaling in the Southern Ocean over the past century reduced the genetic diversity—and possibly the evolutionary fitness—of the region’s humpback whales. https://scim.ag/4anxPpM

YUM!!!

Australians: we don't like guns. This is excellent.

Here's our reporting on the proposed dismantling of the jewel of US atmospheric science, @ncar-ucar.bsky.social. The plan is to break NCAR apart and disburse some parts to other locations (like the research aircraft fleet) and eliminate others. www.nature.com/articles/d41... 🧪 #AGU25 #climate

Trump Announces 5,000% Increase In All Numbers

We are grateful to the National Health and Medical Research Council for granting four of our scientists highly sought after Ideas Grants. https://www.cmrijeansforgenes.org.au/news/cmri-researchers-awarded-four-nhmrc-grants Tony Cesare

3/ I’m relieved to have secured funding to sustain my lab, but am deeply concerned about the long-term health of Australia’s research sector. Our grant structures and peer review systems are in urgent need of reform.

If I may be allowed a moment of fatherly pride. Huge congratulations to Maddy Cesare on being selected for the New South Wales team competing at the Australian Youth Women’s Baseball Championship ⚾️🇦🇺 A big achievement, especially in her first year of eligibility. Baseball is awesome.

Letter from Congress to FDA re: undermining vaccines, page 1 of 6

The most dangerous

New @natcomms.nature.com paper today from Tracy Bryan's lab @cmri.bsky.social: "Nuclear actin and DNA replication stress regulate telomere maintenance by telomerase". Happy our lab could play a small part. Congrats Tracy, Ash Harman, Noa Lamm and the whole team. www.nature.com/articles/s41...

Today. "Or they simply don't know what they are doing" wapo.st/4rE11ib

Science’s 2024 Breakthrough of the Year was lenacapavir, an injectable drug that demonstrated remarkable success at preventing HIV infection with one shot every 6 months. Learn more about last year's #BOTY on #WorldAIDSDay: https://scim.ag/48pk7zZ

The success rate for NHMRC Ideas Grants announced yesterday was just over 8%. That means 11 of every 12 people who applied got rejected. This is a culture changing level of rejection and frankly a point of national shame. This is a crisis for research. I will not rest until we see this resolved.

Thankful for breakthroughs! t.co/Khbj4npOP1

Thank you @cmri.bsky.social for the nomination; @sydney.edu.au for this recognition; and our team for making this research possible.

A Moon Halo So Perfect Last night over New York, a flawless 22° ice-crystal halo formed around the full Moon — a radiant circle shining above the Statue of Liberty.

Neoliberalism's toll: "a weakened public school system, financially stressed universities, and a #CSIRO repeatedly stripped of long-term capability." We have lost "depth, continuity, and trust, conditions that science requires but markets cannot provide." #auspol johnmenadue.com/post/2025/11...

Australia’s algal bloom catastrophe has left more than 87,000 animals dead. What will happen this summer? Six researchers in this space, including myself, have lost their positions at Flinders University in a restructure. theconversation.com/australias-a...

This is why for a long time I've found the Prime Minister's Prizes for Science a rather insulting propaganda exercise www.abc.net.au/news/science... CSIRO funding as a percentage of GDP: 1982-83 = 0.17 2024-25 = 0.03 ... Scientific extinction event imminent?

Over the last century, research has helped improve the early detection and treatment of serious diseases. But future progress is at risk unless we continue federal funding for medical research. #AmericansForMedicalResearch

“CSIRO has announced it will slash up to 350 jobs as the national science agency grapples with long-term financial challenges … with current funding failing to keep pace with the rising costs of running a modern science agency.” Not “challenges”. They’re choices. 😡

My latest for @science.org: A remarkable set of high-resolution climate model runs, computed over 900 (!) days of supercomputing time, are revealing how warming-induced changes to Earth's wind patterns due can prime huge spikes in extreme rainfall. But the MESACLIP runs also do much more than that.

My quote of the day In a world where everyone is behaving honestly, any dishonesty constitutes a big infraction. But, in a world where many people are behaving dishonestly, and the news is filled with stories of their infractions, even big infractions can feel small to the perpetrator. Dan Ariely

Finally! We have a FANCM:RMI inhibitor that is cell active and specifically kills ALT+ cancer cells 🎯 @yuhenglau.bsky.social + my labs just published the first cell-active peptide inhibitors of this critical target in 10-15% of cancers. doi.org/10.1021/acs....

🧵 Our latest preprint is available. It describes an extraordinary case of a boy with two very rare genetic conditions: Fanconi anaemia (FANCB, with a deep intronic pathogenic variant) and embryonic triploid–diploid mosaicism. Read more here 👉 www.medrxiv.org/content/10.1...

Thanks Barb, I guess many folks haven't heard. We lost Bill on October 7, 2025 to cancer. news.ucsc.edu/2025/10/in-m...

The study reveals how actin filaments form at PML nuclear bodies during replication stress and how this nuclear actin assembly protect the genome. A summary of all manuscript details and the study participants can be found here: www.linkedin.com/posts/noa-la...

The first preprint from Noa Lamm’s team @cmri.bsky.social is now available: Anillin-dependent actin assembly at PML nuclear bodies protects genome stability www.biorxiv.org/content/10.1... Delighted our lab could play a role supporting Noa’s vision on this project.

Our paper in Science is out! @souravagrawal.bsky.social, @rlynn.bsky.social, @susvirkar.bsky.social, and the rest of the team show human RPA is a telomerase processivity factor essential for telomere maintenance. This reshapes our thinking about telomerase regulation. www.science.org/doi/10.1126/...