Colorado Blue Columbine on Clear Creek today #nativeplants 🌿

Excellent NYT opinion piece highlighting the past scientific contributions of something many Americans know – the Lewis & Clark expedition – to parallels in modern day science, including the need for proper support of long-term, ambitious aims. Free link: www.nytimes.com/2026/06/28/o...

Out today in Molecular Cell! Lead by Mariia Mikhova and in collaboration with Kefei Yu’s lab @msumgi.bsky.social we dug into the molecular mechanism of class switch recombination in B cells using simultaneous RNA and protein single-molecule imaging. 1/n www.cell.com/molecular-ce...

Two of the most important biomedical breakthroughs came from science of the Gila lizard venom (GLP-1s) and yogurt (CRISPR genome editing). "The system that turned that lizard into a medicine is now being dismantled." gift link nytimes.com/2026/06/20/o...

Please share this gift article from The New York Times with friends, family, sceptics, and People who think that studying weird things is a waste of money. Then follow up with meaningful discussion about what I call 'free range science'. Free without subscription. www.nytimes.com/2026/06/20/o...

When I head to Washington, I will be the first woman in Congress with a science PhD. That matters. At a time when science is under attack, Congress needs more leaders who understand the value of evidence-based decision-making.

Always a thrill to be back at Molecular Horizons Institute (University of Wollongong) to image my Lovely on Captain Krios.

An unapologetically angry post about what’s being done to US science:

While BioNtech & Moderna become household names because of their Covid vaccines, those emerged from different projects: finding ways to treat the most challenging cancers. They hypothesized that we could vaccinate patients against their own tumors, & evidence is mounting that they were right! 1/n 🧪

From Joelle Pelletier and Rebecca Buller in the Perspective "...seven engineered and three auxiliary enzymes, including industrially atypical enzyme classes...which each required extensive engineering (more than 50 mutations per enzyme on average)" www.science.org/doi/10.1126/...

Biocatalysts can build big molecules. A team at Merck & Co. developed a suite of enzymes that stitch together their oral PCSK9 inhibitor enlicitide. My latest for @cenmag.bsky.social cen.acs.org/pharmaceutic... #chemsky

Did you know that Pierre Chambon's laboratory was the first to use the term "nucleosome" in 1975 ? www.cell.com/cell/fulltex...

The turning point for rare diseases, which affect >300 million people around the world. A call to get rid of its many structural obstacles, to consider it as molecular surgery unlike drug treatments gift link: www.nytimes.com/2026/04/09/o...

i am sick and tired of dumb old white men with reptilian brains (three examples below) making bad decisions that impact all of us.

Nobel Laureate Jack Szostak “This country has given me endless opportunities…: The America we inhabit today bears almost no resemblance to the country I chose all those years ago” newsletter.ofthebrave.org/p/im-a-nobel...

"All of these things frighten me, and they should frighten you as well. I made the decision to create a life for myself here, because I viewed this as a place that rewarded determination, hard work, and integrity. It still has a chance to be that place again." open.substack.com/pub/ofthebra...

Waking up to the awe-inspiring images from NASA at the same time the US President is implying that he will commit genocide, I can't think of a better quote for the times than this one from Apollo astronaut Edgar Mitchell. I added it to today's Earthset image:

Sorry, Science chemistry desk is closed today while I watch this video over and over again www.ncaa.com/video/basket...

Have you heard the story of Barkley’s good friend Lin, a Chinese immigrant scientist in Iowa? www.wbur.org/onlyagame/20...

Indulged in a distraction from it all… Just once or twice a year one can experience the massive organ in the Sydney Opera House. Organist ANNA LAPWOOD.

An important seasonal installation in the Cesare lab. March Madness bracket is up. Go Tar Heels! 🏀

More than 60% of Australian medical researchers left active research roles between 2019 & 2024 because they could not make ends meet - while my costings from the PBO suggest the govt could more than double annual spending from the MRFF without any effect on its base level of funding.

And the Lancet's editorial that goes with it www.thelancet.com/journals/lan...

New: Trump admin moves to pull supercomputing center out of top weather and climate research center (NCAR) in Boulder, Colo. Part of its effort to "break up" the lab. www.cnn.com/2026/02/13/w...

RNA comes close to copying itself | Science www.science.org/doi/10.1126/...

So, so, honored by this award—it is daunting to know that my heroes have won this award! Thanks to my heroes and mentors, and my trainees, who are everything!!!!

it looks as shiny and wonderful as the day you made it!

another stunning piece by the amazing and uninimitable @bryanwelm.bsky.social . I would recognize his pieces anywhere!

No, DeepMind has not solved the protein folding problem. #Alphafold predictions are valuable hypotheses and accelerate but do not replace experimental structure determination.

Work hard — play hard 💪🧬🧫

Right now, the Government is starving medical research of full funding, even as it claims that science and research are national priorities. If our leaders truly value science as much as they say, then they must back their words with action—and fund it properly. Join the campaign!

Raven-Flóki & Eric the Red have a lot to answer regarding naming Iceland and Greenland, respectively. However, I don't they could have counted on the Chief of Vineland (Leif Eriksson's name for America) to mix them repeatedly up even if not drunk.

His work laid the foundation for quantum dot technology now used in solar panels, television screens and medical imaging.

The title of this paper is "Specificity of the stabilizing interaction between intrinsically disordered protein sequences and G-quadruplexes in RNA". We show a minimal RGG-rich peptide selectively (compared to other G-quads) stabilizes the structure of the human telomeric TERRA RNA G-quadruplex.

If you have cartoonists on your mind today, read this letter Charles Schulz wrote in 1970: "I believe that our greatest strength lies always in the protection of our smallest minorities." www.kqed.org/arts/1385272...

Powerful piece in STAT this morning from some NIH staff members who have resigned www.statnews.com/2026/01/10/n... 1/3

NIH staffers protest "an organization that has lost its integrity" www.statnews.com/2026/01/10/n...

Some people think science is just for nerds, but science is the foundation of the modern world and science is what made America great. Even though many of us don’t work directly in space science, we were inspired to become scientists by NASA. Destroying it makes zero sense.

If Martin Kettle would have read the great book Humankind by @rutgerbregman.com, this story would not have come as a surprise. Anyway, it is good he realises that journalists, including himself, are partially to blame for our skewed understanding of society. www.theguardian.com/commentisfre...

A new #ScienceAdvances study shows that commercial whaling in the Southern Ocean over the past century reduced the genetic diversity—and possibly the evolutionary fitness—of the region’s humpback whales. https://scim.ag/4anxPpM

YUM!!!

Australians: we don't like guns. This is excellent.

Here's our reporting on the proposed dismantling of the jewel of US atmospheric science, @ncar-ucar.bsky.social. The plan is to break NCAR apart and disburse some parts to other locations (like the research aircraft fleet) and eliminate others. www.nature.com/articles/d41... 🧪 #AGU25 #climate

Trump Announces 5,000% Increase In All Numbers

We are grateful to the National Health and Medical Research Council for granting four of our scientists highly sought after Ideas Grants. https://www.cmrijeansforgenes.org.au/news/cmri-researchers-awarded-four-nhmrc-grants Tony Cesare