Matthias Flotho
@mflot.bsky.social
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📥 470
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PhD candidate at Helmholtz Institute for Pharmaceutical Research Saarland
pinned post!
ggdiceplot 1.2.0 is now on CRAN. It fixes the 1.1.0 bug where no pips were rendered. Lesson learned: we need better visual testing. Any recommendations for checking, in an automated way, that plots not only compile but also render as expected in R?
github.com/maflot/ggdic...
#CRAN
#Datavis
#testthat
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GitHub - maflot/ggdiceplot: R package for visualising high-dimensional categorical data. Fully ggplot compatible implementation for the diceplot plotting library
R package for visualising high-dimensional categorical data. Fully ggplot compatible implementation for the diceplot plotting library - maflot/ggdiceplot
https://github.com/maflot/ggdiceplot
2 months ago
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Ali Maximilian Erturk
4 days ago
Our recent work in @Nature, MouseMapper uses foundation-model AI, mapping perturbations in mouse body cell-by-cell, revealed unexpected facial nerve damage. Proud to see >75K accesses & >60 news stories in the first week. Paper->>
www.nature.com/articles/s41...
Next
www.biorxiv.org/content/10.6...
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github.com/FlowRegSuite...
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6 days ago
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MetJam
7 days ago
34.8ºC at Kew Gardens breaks its May AND June records by OVER 4ºC for its May record set in 1922 and by 0.2ºC for its June record set in 1976. Unprecedented heat for the UK in late May, and likely to be bettered tomorrow. A rounded 35ºC temperature should not happen in May.
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Nature Portfolio
21 days ago
Scientific figures can strongly influence how research findings are interpreted. This ‘How to’ Comment article in Nature Human Behaviour outlines a practical strategy for creating figures that communicate clearly across audiences and scientific contexts.
go.nature.com/3R00b1t
#Academicsky
🧪
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James Ferguson
25 days ago
kuva v0.2.0 Now over 60 plots! New plot types: Gantt, Network, Waffle, Horizon, PopulationPyramid, Joint, Clustermap, ROC, PR, Lollipop, Survival, Raincloud, Slope, Venn, Parallel, Mosaic, Streamgraph, Radar, Treemap, Sunburst, Bump, Funnel, Rose, Calendar, Legend, Text
github.com/Psy-Fer/kuva
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The Fromm Lab
27 days ago
Science has missed a real giant. Not uncontroversial, but inspiring nevertheless. Here is an interview which was recorded a few days before his death.
www.youtube.com/watch?v=Zxg3...
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He changed science forever. He spoke with us on that, AI, Trump and immortality just before he died.
YouTube video by Scientific American
https://www.youtube.com/watch?v=Zxg38eUL5IY
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Quite interesting read:
www.nature.com/articles/s41...
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Show us the evidence for the value of medical AI - Nature Medicine
Claims that medical AI is improving care must be backed by appropriate evidence.
https://www.nature.com/articles/s41591-026-04389-4#article-info
27 days ago
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Matthias Flotho
The New York Times
about 1 month ago
J. Craig Venter, a scientist and entrepreneur who decoded the human genome, has died at 79.
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J. Craig Venter, Scientist Who Decoded the Human Genome, Dies at 79
A risk-taking outsider, he brought speed, competition and controversy to one of science’s biggest races.
https://nyti.ms/49hkzRS
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de.NBI & ELIXIR Germany
about 1 month ago
🚀
#BioHackathon
Germany 2026: Call for Projects! 🧬 Submit your innovative life science project ideas! 📅 Deadline: 15 July 2026 📝 Max 500 words 🔗 Align with
#deNBI
(ELIXIR Germany) topics Join us to solve bioinformatics challenges! 💻✨ Read more:
www.denbi.de/de-nbi-event...
#Bioinformatics
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James Ferguson
about 1 month ago
Slowly going through all the checks for a new version of kuva to be releases. Probably going to take another few days. But i'm up to 59 plot types now (with lots more sub variants). There is one more plot in a PR, don't worry i'll make it an even 60
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Matthias Flotho
Helmholtz KLIMA
about 1 month ago
#HelmholtzKLIMA
-Datenbank - Expertise im Überblick: Digitalisierung für nachhaltige Wertschöpfungsketten Stefanie Kunkel beschäftigt sich am
@rifs-potsdam.bsky.social
mit der Frage, wie sich die globale Digitalisierung sozial-ökologisch und gerecht gestalten lässt. Zum Profil:
t1p.de/ojvod
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Stefanie Kunkel
https://t1p.de/ojvod
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Science Magazine
about 1 month ago
The genome of the hepatitis D virus, with just 1700 bases of RNA, was squeezed onto a quantum computer. Learn more:
https://scim.ag/4mCifuv
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Matthias Flotho
Helmholtz KLIMA
about 1 month ago
#EarthDay2026
: Wir haben es in der Hand, unseren Planeten zu gestalten! Ihr habt Interesse an neuesten Forschungsergebnisse & Lösungen für einen lebenswerten Planeten von
@helmholtz.de
? Dann schaut ins online Programm der Earth Week vom AK Forum Nachhaltigkeit! ▶️
t1p.de/vp7pm
#OurPowerOurPlanet
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Earth Week
Earth Week
https://t1p.de/vp7pm
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Matthias Flotho
Melanie I Stefan
about 1 month ago
So, OpenAI, whose entire business model relies on some overhyped dudebros using vast amounts of stolen data and stolen labour, is releasing a specialised GPT for the life sciences. And naming it, apparently without any sense of irony or self-awareness. Rosalind.
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Matthias Flotho
Deutsche Umwelthilfe
about 2 months ago
Bezahlbarer ÖPNV statt Tankrabatt – 29-Euro-Ticket jetzt! EU-Kommission empfiehlt günstigere Tickets, um sofort Sprit zu sparen. Tankrabatte dagegen verschärfen die Krise. Bei geringerem Preis nutzen mehr Menschen den ÖPNV und lassen dafür das Auto stehen.
mitmachen.duh.de/deutschlandt...
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Petition: 29-Euro-Ticket statt Verbrenner-Subventionen!
Setz dich mit uns für ein günstigeres Deutschlandticket ein. Jetzt Petition unterschreiben!
https://mitmachen.duh.de/deutschlandticket/
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Matthias Flotho
about 2 months ago
⭐️PhD Cognitive/Computational Psychology ⭐️ Use Reinforcement Learning + computational modelling to study how we form beliefs in the face of unreliable information (with me +Tali Sharot). Full funding for those eligible for UK home fees. Deadline 18/5. Please share!
@queenmarycbb.bsky.social
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Retraction Watch
about 2 months ago
Weekend reads: Half of social science ‘doesn’t replicate’; ‘Scientific ghosts: Life after retraction’; multisensory learning paper retracted
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Weekend reads: Half of social science ‘doesn’t replicate’; ‘Scientific ghosts: Life after retraction’; multisensory learning paper retracted
If your week flew by — we know ours did — catch up here with what you might have missed. The week at Retraction Watch featured: A citation alert led researchers to a network of fake articles. But w…
https://retractionwatch.com/2026/04/04/weekend-reads-half-social-science-doesnt-replicate-scientific-ghosts-multisensory-learning-paper-retracted/
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Matthias Flotho
Megan Fox
about 2 months ago
So you're telling me Claude functions by screaming at itself "WRITE GOOD CODE NO BUGS SECURE VERY STABLE", mashes compile button, reads back the error and yells ONLY GOOD CODE NO BUGS at itself again while crying and copying random things from Stack Overflow until it compiles? it just like me fr fr
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Matthias Flotho
Helmholtz Institute Würzburg
2 months ago
In March, we had the pleasure of welcoming the Universitätsbund to HIRI for one of their board meetings. In addition to their own agenda, our guests received a brief introduction to the institute & joined a tour of our construction site.🧬👷 Thanks for visiting! 👉
www.helmholtz-hiri.de/en/newsroom/...
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First-hand insights into cutting-edge RNA research
The board of the Universitätsbund met at the Helmholtz Institute Würzburg
https://www.helmholtz-hiri.de/en/newsroom/news/detail/news/first-hand-insights-into-cutting-edge-rna-research/
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Matthias Flotho
bioRxiv Bioinfo
3 months ago
stMCP: Spatial Transcriptomics with a Model Context Protocol Server
https://www.biorxiv.org/content/10.64898/2026.03.11.710153v1
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ggdiceplot 1.2.0 is now on CRAN. It fixes the 1.1.0 bug where no pips were rendered. Lesson learned: we need better visual testing. Any recommendations for checking, in an automated way, that plots not only compile but also render as expected in R?
github.com/maflot/ggdic...
#CRAN
#Datavis
#testthat
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GitHub - maflot/ggdiceplot: R package for visualising high-dimensional categorical data. Fully ggplot compatible implementation for the diceplot plotting library
R package for visualising high-dimensional categorical data. Fully ggplot compatible implementation for the diceplot plotting library - maflot/ggdiceplot
https://github.com/maflot/ggdiceplot
2 months ago
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Matthias Flotho
PharmaScienceHub
2 months ago
🔬 PSH Core Facility Tech Talks Recap: High-Resolution Microscopy Core Facility Last week, we got an in-depth look at imaging techniques, access procedures & a Pretubulysin research project. More TechTalks to follow! 👉
https://psh.digital/xwgcl
Photo: PSH
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Built a small open-source template to manage multiple SSH nodes with tmux, track Claude Code/Codex sessions, and keep context in sync. Hope this helps someone else building across multiple machines.
github.com/maflot/multi...
#opensource
#ssh
#tmux
#claudecode
#codex
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GitHub - maflot/multi-clone-code: Easy setup for a multi claude code session across working nodes
Easy setup for a multi claude code session across working nodes - maflot/multi-clone-code
https://github.com/maflot/multi-clone-code
2 months ago
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Matthias Flotho
Helmholtz Institute Würzburg
2 months ago
Applications close today. ⌛👇
add a skeleton here at some point
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Joseph Guhlin
2 months ago
Coconuts
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ggdiceplot v1.1.0 is now on CRAN 🎲 New pip_scale controls pip size: less white space, clearer plots, adjustable layout.
github.com/maflot/ggdic...
cran.r-project.org/web/packages...
#CRAN
#Datavis
#diceplot
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GitHub - maflot/ggdiceplot: R package for visualising high-dimensional categorical data. Fully ggplot compatible implementation for the diceplot plotting library
R package for visualising high-dimensional categorical data. Fully ggplot compatible implementation for the diceplot plotting library - maflot/ggdiceplot
https://github.com/maflot/ggdiceplot/tree/main
2 months ago
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Matthias Flotho
Helmholtz Metadata Collaboration
2 months ago
Don’t miss our next
#HMC
Open Office Hour! Talk directly to metadata experts and get tailored advice. Participation is free and open to everyone. 📅 When: 19/03/2026 🔗 Registration:
helmholtz-metadaten.de/events/hmc-o...
We look forward to welcoming you!
#HMC_OpenOffice
@helmholtz.de
@kit.edu
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Matthias Flotho
Stegle Lab
3 months ago
We’re excited to announce the 2nd edition of the Health Privacy Challenge. 🍅🫐 What started last year as a CAMDA community challenge has grown into a benchmarking study of generative models for biologically useful and privacy-preserving synthetic omics, focusing on trade-offs across evaluation axes.👇
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Matthias Flotho
de.NBI & ELIXIR Germany
3 months ago
🧬 5th BioHackathon Germany – Save the Date! 📍 Göttingen | 📅 Dec 7–11, 2026 Mark your calendars! We’re bringing together life scientists, bioinformaticians, and data stewards for an intense week of hacking. 💻✨ 🚀 Mid-April: Project applications open 🔗
www.denbi.de/de-nbi-event...
#BioHackathon
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Matthias Flotho
Matthias Stahl
3 months ago
You might have noted that we visualize constituencies and their winners as cartogram. We do this with a similar technique that
@driven-by-data.net
has already used last year. The method is based on centroids, Delaunay tessellation and a force directed graph layout.
add a skeleton here at some point
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McSweeney's
3 months ago
In a competitive field like academia, everyone feels like a fraud sometimes, whether it’s a scathing peer review, a bad comment from a student, or being shooed away by campus security when you get caught eating apple cores and chicken bones out of the dining hall dumpster at 3 a.m.
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How to Overcome Imposter Syndrome in Academia When You’re Six Raccoons Living in a Fjällräven Parka
Imposter syndrome is real. In a competitive field like academia, everybody feels like a fraud sometimes, whether it’s a scathing peer review, a nas...
https://buff.ly/zixoNTS
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scverse
4 months ago
We will have our next community meeting on Tue, Feb 17, 2026, 11AM CST/ 9AM PST ! Kexin Huang, will be presenting on Biomni: a general-purpose biomedical agent. Details in 🧵
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Matthias Flotho
allen institute
4 months ago
Giving science a boost. ⚡🔬 We're partnering with
@anthropic.com
to design and deploy custom AI agents that will help scientists turn big data into scientific discoveries faster. 🔗
https://alleninstitute.org/news/partnering-with-anthropic-to-supercharge-research-to-help-cure-disease/
🧠📈
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Partnering with Anthropic to supercharge research and help cure disease
From months to hours, autonomous AI agents will accelerate research in the quest for cures.
https://alleninstitute.org/news/partnering-with-anthropic-to-supercharge-research-to-help-cure-disease/
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Matthias Flotho
4 months ago
At the start of January, Johanna,
@rorak.bsky.social
and Sven traveled to Vancouver where Johanna presented our paper "Smaller and More Flexible Cuckoo Filters"(
epubs.siam.org/doi/abs/10.1...
) at the ALENEX 2026. (1/4)
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Jens Hör
4 months ago
Great opportunity to join the lab of
@patrick-pausch.bsky.social
!
www.linkedin.com/feed/update/...
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PhD advertisement - Pausch lab | Patrick Pausch | 15 comments
Please share! 📤 The Pausch lab at Vilniaus universitetas / Vilnius University is looking to recruit PhD students to work on: ⚔️ 🛡️: Bacterial Immune Systems (CRISPR, retrons, & beyond) 🧬 ✂️: De...
https://www.linkedin.com/feed/update/urn:li:activity:7419288162033836032/
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Sholto David
4 months ago
Figure 5. Sudden quarrelling of spouse due to misuse of wireless sensor technology:
doi.org/10.5539/jpl....
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scverse
4 months ago
We will have our first community meeting of 2026 on Tue, Jan 20, 2026, 11AM CST/ 9AM PST ! Ian Ferenc Diks (
@ianfd.bsky.social
) will be presenting on SingleRust: A High-Performance Toolkit for Single-Cell Data Analysis at Scale.
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Onisillos
4 months ago
"The target was numbers, and quality was mentioned only in terms of a journal’s prestige, never the work itself."
www.nature.com/articles/d41...
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I’m going to halve my publication output. You should consider slow science, too
If we don’t slow down, the research enterprise is going to crash, argues Adrian Barnett.
https://www.nature.com/articles/d41586-025-04061-w
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Pretty cool visualization tool for inspecting read alignments!
#datavis
#bioinformatics
#openscience
add a skeleton here at some point
5 months ago
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Matthias Flotho
Helmholtz Institute Würzburg
5 months ago
Check out the latest paper by
@carmen-aguilar.bsky.social
, which also involved our
#HIRI
group leader
@emmanuel-saliba.bsky.social
and his lab. It was recently published in
@natmicrobiol.nature.com
:
doi.org/10.1038/s415...
Congratulations to all authors! 👏🎉
add a skeleton here at some point
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The Parkinson's Disease Drug Tolcapone and Analogues are Potent Glycomimetic Lectin Inhibitors of Pseudomonas aeruginosa LecA
doi.org/10.1002/anie...
5 months ago
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Matthias Flotho
allen institute
5 months ago
Every brain tells a story. What will we learn when we listen? Together with
@uwmedicine.bsky.social
, we're embarking on an ambitious mission - building a functional, cellular map of the human brain.
https://alleninstitute.org/news/mapping-the-brain-to-improve-lives/
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Mapping the brain to improve lives
A collaborative effort between UW and the Allen Institute is creating a first-of-its-kind brain atlas, paving the way for breakthroughs in brain health.
https://alleninstitute.org/news/mapping-the-brain-to-improve-lives/
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Aligning Science Across Parkinson's
5 months ago
🧠 CRN Team Kordower developed a co-pathology mouse model combining tau, amyloid-β, & α-synuclein. They show co-pathologies synergistically trigger an amplified neuroimmune response, with expanded CD4+/CD8+ T cells & increased CD68+ microglia. 🔗 Check out the full
#preprint
:
https://bit.ly/4jAHzzl
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Matthias Flotho
ggdiceplot 1.0.1 is out now! From today, {diceplot} is deprecated and treated as the legacy implementation, all new development and features will go into {ggdiceplot}. Repo:
github.com/maflot/ggdic...
Docs:
dice-and-domino-plot.readthedocs.io/en/latest/
Paper:
tinyurl.com/ggdiceplot
#rstats
#ggplot2
6 months ago
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For anybody working on thermal imaging of faces: The thermal-face-alignment TFAN package has just dropped on pip.
github.com/openscivisio...
#computer-vision
#thermal-imaging
#thermal-recognition
#thermal-landmarks
#face-alignment
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5 months ago
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Matthias Flotho
bioRxiv Bioinfo
6 months ago
Copula modeling of gene coexpression in single-cell RNA sequencing data
https://www.biorxiv.org/content/10.64898/2025.12.04.692380v1
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Chuan Wang
6 months ago
How does a bacterial small RNA evolve new functions? Our new study reveals the stepwise evolutionary journey of UhpU, a 3′UTR-derived sRNA in E. coli and relatives. It evolved from a metabolically-focused regulator to one with expanded targets and biogenesis manner.
www.pnas.org/doi/10.1073/...
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ggdiceplot 1.0.1 is out now! From today, {diceplot} is deprecated and treated as the legacy implementation, all new development and features will go into {ggdiceplot}. Repo:
github.com/maflot/ggdic...
Docs:
dice-and-domino-plot.readthedocs.io/en/latest/
Paper:
tinyurl.com/ggdiceplot
#rstats
#ggplot2
6 months ago
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Matthias Flotho
Nature Portfolio
6 months ago
Approximately 96% of the images from some space observatories in low Earth orbit could be tainted over the next decade due to light contamination from satellites, according to an analysis in Nature.
go.nature.com/3Y7eTUA
🔭 🧪
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