Thank you for highlighting our work! CD4 T cell differentiation is a dynamic process, shaped by interaction with different antigen-presenting cells rather than fixed early programming. If you want to know more about it, please see below 👇🏼

TCF1 is a master regulator of T cell stemness – but can it make exhausted cells go backwards? We setup a CRISPR KI system to ask this question, and the answer was unexpected. www.nature.com/articles/s41...

Ever wondered what happens if you remove Tfh cells from established germinal centres?

What a joy to host Michelle @linterman.bsky.social at the LUMC and spend more time together at the #NVVI!! She shared wonderful work on ectopic Germinal Centers in the lung (www.pnas.org/doi/10.1073/...) and a new exciting story that I can't wait to see published soon!!

mTOR regulates translation of cytokines through AU-rich elements within their 3′UTR! Great new work from the @monikawolkers.bsky.social lab!

Germinal center B cells rely on ZFP36L1 and ZFP36L2 to control cell division and avoid replication stress that leads to apoptosis @sciimmunology.bsky.social @martint-babraham.bsky.social www.science.org/doi/10.1126/... @babrahaminst.bsky.social

🚨 New paper alert!! RNA-binding proteins ZFP36L1 & ZFP36L2 act as guardians of genome stability in fast-dividing germinal center B cells. A new mechanism showing how post-transcriptional control keeps our immune cells in check! #RNA #Bcells #GenomeStability www.science.org/doi/10.1126/...

This is great!

I am deeply honored and humbled to receive the 2025 KNAW Early Career Award from the Royal Netherlands Academy of Arts and Sciences! 🌟 This recognition means a lot, especially as a scientist working on fundamental immunology. Grateful to everyone who has supported and inspired me along the way! 🙏🏼

Happy to share the first pre-print of the lab! 📢 💡Do you want to know how CD4 T cells decide their fate? We used a mouse vaccination model to trace endogenous polyclonal CD4 T cells on their journey towards Th1 or Tfh differentiation. www.biorxiv.org/content/10.1...

@biorxivpreprint.bsky.social Requirements for development of T-helper1 and T-follicular helper cells from a common precursor @unileiden.bsky.social www.biorxiv.org/content/10.1...

Thrilled to have our latest research @wehi-research.bsky.social published in @natimmunol.nature.com www.nature.com/articles/s41... This work was an outstanding partnership between talented PhD student Len Dalit (now postdoc, no 🦋) and bioinformatician @chinweetan.bsky.social Thread below...

it is finally out! 👇 our #ML pipeline SONAR, which can predict the protein abundance in #immune cells. Using sequence features present in the #RNA. With @bnicolet.bsky.social Supported by the @erc.europa.eu [email protected] www.science.org/doi/epdf/10....

Congratulations to you all! It's a pleasure to see this beautiful work online 🎉 ZFP36-family of RNA-binding proteins enables Treg cells to enforce immune homeostasis. www.nature.com/articles/s41...

We celebrate the first birthday of the lab! 🎂 Stay tuned for the great science we have in the pipeline 🎉

Always great to be at the EMBL! Looking forward to a full day of exciting science! #EMBLRBP

Amazing stuff from @marvintanenbaum.bsky.social! Long-term imaging of individual ribosomes reveals ribosome cooperativity in mRNA translation: Cell www.cell.com/cell/fulltex... #RNAsky #RNABiology