people keep voluntarily impaling themselves on the "you should all stop being mean to AI because it is BIG and STRONG and my FRIEND" stake, and I'm politely asking them to stop because it's embarrassing

"Did you see what Mark Cuban posted? Oh did you see the clapb—" You shake yourself awake in the cold North Atlantic water. You are not online. It is July of 1858. You are a baleen whale, and you have changed your mind. The future most not come to pass. The telegraph cable must break.

Cannot wait for my annual rewatch for Arthur Christmas. Complete with hot Santa Steve Claus voiced by Hugh Laurie and his elf assistant who is down extremely bad

Updated with a pristine, HD copy courtesy of Leon Thomas @renegadecut.bsky.social Watch Inside CECOT now

60 minutes CECOT segment. Recorded through my browser. HD quality. Not phone. Spread it around. If you're press, it's yours. Go nuts. It's streaming on a Canadian website, but there is no telling for how long. www.filemail.com/d/wkcdttnacp...

Workshopping mnemonics for teaching the orgo 2 crowd 13cnmr shift regions. Current fave: "Keys to the car aren't there, Alfonso, you bastard!" For ketone/ald, other carbonyls, Arene/alkene, triple, alpha to F, O, N, S, boring #chemed

i just called the DC office of Sen Dick Durbin who is generally terrible and cannot be relied upon 202-224-2152 his staffer answered after the first ring and was unfamiliar with the bill. he has not taken a position on it. if you live in Illinois, please give him a call.

Gift link, probably the funniest thing the Wall Street Journal has done this year.

this has exactly as much scientific basis as their antivax garbage and is somehow even more directly aimed at killing people fuck this absolute monster

this really needs to be viewed as at the same level of science-rejection as getting rid of all the child vaccines

"I didn’t have the courage to come out until I was 21, and that means 21 years of pain, 21 years of unwavering homesickness that only went away when I was able to get the care that I needed. And my biggest regret in life is that I never had a childhood without that pain.”

Question for the phys org people out there: Are there estimates of rel. electrophilicity of say an acylium ion on the Mayr scale? My searching has come up dry #ChemSky #AskChemSky

Super interesting. Seems plausible to me that as people believe they are benefiting from collective action regulation (rent controls) they are more supportive of other public interest action. This is also Berlin, so the policy feedback processes may be different there than the US or elsewhere.

Jarry for Skinner?! Kyle Dubas what on earth are you doing, mama? Do we need to trade places with the new mayor and give him a whirl as GM? The cosmic horrors of being a pens fan. #penguins

If they pretend they haven’t heard about the story of the day, end the interview right there. “I’m sorry, Senator, we wanted to get your perspective on this story, but it seems you’re not fully aware of what’s going on.”

I mean, we are 100% all the way back to the original debate with Derek's 2015 "The End of Synthesis" post | it was a "'synthesis requires expertise' versus 'let us democratize synthesis'" debate back then, and now it is "the computers/robots will help us de-artisanize synthesis" in 2025

And here it is – Annulative Editing – aka The Monster Mash. What a super collab #PfizerChemistry & @sarponggroup.bsky.social In 1 pot, activated pyrimidines with bis-nucleophiles like amino-pyrazoles & other small hets to deliver 6/5 hets and other useful products #MyFirstJACS #ChemSky #ChemChat

Obsessed with this man ordering ketchup on Amazon at the coffee shop. He's had like 12 different varieties of ketchup up

UNCW's Dept of Chem and Biochem is looking for four (4!) new members this cycle including: Asst Professor Analytical Chem Asst Professor Physical Chem Lecturer - Bio- and general Chem Lecturer - General Chem Our dept is a great place to work and Wilmington's a blast! #ChemSky #ChemJobs Links ⬇️

Just hear me out: maybe the Democratic Party’s problem is that the party leadership is full of people incapable of realizing that Matt Yglesias has terrible political instincts.

Imagine posing for a photographer friend who sells your image to iStock and a year later, you see this is what The Washington Post has done with the image of you walking on a beautiful fall day

UNCW's Dept of Chem and Biochem is looking for four (4!) new members this cycle including: Asst Professor Analytical Chem Asst Professor Physical Chem Lecturer - Bio- and general Chem Lecturer - General Chem Our dept is a great place to work and Wilmington's a blast! #ChemSky #ChemJobs Links ⬇️

Reposting this jobs threads bc 4 sep ones was a stupid idea lol.

AU where everything is the same but tbqh means "to be queer and honest"

Used book store coming in STRONG today with a whole cadre of desk refs for my students as they write their papers and theses.

Happy LGBTQ+ in STEM Day! I’m celebrating with the dapper Invisible Enby, who is a queer fashion metaphor for the way dark matter shapes visible matter in the cosmos. Want to learn more? Preorder my new book, where they appear! 🧪 www.penguinrandomhouse.com/books/746817...

Alice Wong taught us that disabled people don’t just leave memories behind—they leave infrastructure. Lineages of care. Methods of collectivity, survival. She named the connective tissue that holds our communities together, even across death, even across the losses that come too fast and too often.

"Alice supported and took many people with Long COVID under her wing — I was honored to call her a colleague and friend." @mileswgriffis.bsky.social in @thesicktimes.org's obituary for the great Alice Wong: thesicktimes.org/2025/11/15/a...

I love a good complex natural product. This one has two α-tropolones, 10 asymmetric stereocenters, and a a labile hemiketal. After a longstanding effort, chemists in Seth Herzon's lab have made (–)-gukulenin A. My latest for @cenmag.bsky.social cen.acs.org/synthesis/me...

The bigger fight? Buddy, I die without health care and your pals in the Senate — none of whom will ever go without access to lifesaving medical care — told me they were gonna fight so my premiums don't go up 50%. And then they folded.

"Frankenstein’s failure was not ambition but abandonment—a pattern that science repeats whenever discovery outpaces reflection. Contemporary biotech institutionalizes this dynamic... Scientists do the initial work, whereas the moral labor is subcontracted to ethicists, policy-makers, or the public."

Her sister wrote my favorite essay about her. She points out that RF would have been famous even if she'd never looked at DNA www.thelancet.com/journals/lan...

My ask of any science enthusiasts who tell the story of Rosalind Franklin: Don't make her life be about the DNA debacle. She died far too young, but she was a promising scientist in her own right, a mentor and scientific author. Not for Watson or Crick, but for her legacy.

Truly generational levels of hatred. Remarkable.

Tonight's exam night joke: What did the Wicked Witch of the West say to the alkene? I'll get you my pretty, and your little sp, too!

i have said this before but when “getting rid of race in admissions” for the administration means “you can’t even try to reach out to underrepresented communities and encourage them to apply and if you do it is illegal discrimination against white people” then the actual goal here is segregation

Do I know anyone who has applied for/been awarded a K18?

rarely have I more acutely felt the dynamic by which Dems are held responsible for the rhetoric of every random left-leaning person on the internet and Republicans are not even asked to answer for their own personal words

Turning Point USA made a literal watch list of professors, primarily women, queer folks and people of color, and made us targets of political violence. I’ve received hate mail and harassment and death threats off and on for nearly a decade in part due to that man’s organization so 🤷🏽‍♀️

No elected official Democratic party will be as cruel about Kirk's death as Mike Lee was about the death of Melissa Hortman. wisconsinexaminer.com/2025/06/17/s...

The anti-trans and anti-abortion contingents are united on a variety of tactics/bigotries, but one of their top ones is about turning Big Brother into Big Neighbor (or, in this case, I guess ~ Big Student ~). The goal is to make everyone with an ounce of knowledge or compassion afraid to show it.

IT'S FINALLY TIME! BakeOff is BACK. You know what that means ChemBakeOff reaction/meme thread.

two thoughts. 1) this prose is *rough*. 2) describing weiss as possessing a “shit-kicking anti-establishment disposition” is evidence you’ve suffered a brain injury

New Carly Rae Jepsen to bless the first day of classes....SUBLIME. AND we're getting EMOTION-SideC? shaking honestly www.youtube.com/watch?v=_3Jm...

🚨NEW PAPER ALERT @jeflip.bsky.social / @lipshultzsbu.bsky.social out in ACS Catalysis, feat. my rockstar undergrad Celeste Barefoot who worked in this during her REU! She's applying for PhD programs this fall!! 🔗below

In addition to basically serving as genocide apologia - because this is what this is, and make no mistakes - they also put it under the topic of 'Israel and Antisemitism.' They believe that fighting antisemitism means denying a genocide, and this makes everything more dangerous for Jews as well.

Running a little Hajime Ito group chem to cook up some silyl boronates! GC looking good so far 😎 #RealTimeChem

"At a moment when the language of politics is so dour and so dark, it’s important to understand that the tonic to the darkness is not imitating it, but rather to marshal the same lightness and joy that also characterizes our lives." --Mamdani, in this interview: