#LivingArchitectures We put cells and cytoskeleton filaments on the architecture of the musée d'Orsay. www.musee-orsay.fr/fr/agenda/ev... Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night. -> Two shows on the 24th and 25th of January.

Now live, and thanks to @erictopol.bsky.social for organising this!

📣 Paper alert! I am delighted that our paper exploring the impact of Neanderthal-derived variants on the activity of a disease-associated craniofacial enhancer has been published in Development today! journals.biologists.com/dev/article/...

Huge congrats to the team of project "PatCorg" for the prestigious ERC Synergy grant dedicated to studying organoids to uncover mechanisms underlying cortical development: A Pierani (@ipnp.bsky.social), S Nedelec (Institut Monod), S Descroix and B Sorre (Institut Curie), and A Baffet (Inst Curie).

Dan Perez founded the #FSHD Society to foster research & help patients w this painful & debilitating muscular dystrophy. It was a privilege to have known this brave, caring, smart person who was instrumental in getting research money for FSHD, a strange epigenetics-related disease. Melanie Ehrlich

It was a privilege to have known Dan, a brave, caring, loving, & extremely smart person who was instrumental in getting research money for FSHD, a strange epigenetics-related disease. My deepest sympathy for his lovely and loving wife Sue & for his many devoted friends. Melanie Ehrlich #Epigenetics

How do pleiotropic TFs generate organized diversity in developing tissues? @spinalorga.bsky.social shows that PAX3 & PAX7 organize #SpinalCord by acting as both repressors & pioneer activators, regulated by #morphogens to ensure precise neural subtype specification @plosbiology.org 🧪 plos.io/4qumsla

Intussusceptive angiogenesis: bridging in vivo and in vitro observations link.springer.com/article/10.1... Thanks, Dr. Steven Mentzer and Dr. Maximilian Ackermann🙏 for this insightful highlight of our recent PNAS paper on #IntussusceptiveAngiogenesis😁 www.pnas.org/doi/abs/10.1...

🎂 Mon blog (Neuro)biologie et société (neurobiologieetsociete.org) associé au @cafe-sciences.org a 10 ans en ce mois d'octobre 2025 ! neurobiologieetsociete.org Les 5 billets les plus populaires au cours de ces 10 ans 👇 : #CultureScientifique #vulgarisationscientifique

So sad to hear the news - John truly was an inspiration to so many, and one of a kind. www.cam.ac.uk/research/new...

Establishment of a mouse hepatocellular carcinoma tumoroid panel recapitulating inter- and intra- heterogeneity for disease modelling and combinatorial drug discovery biosignaling.biomedcentral.com/articles/10.... another big milestone from the Maina lab @crcm.bsky.social ! Contratulations!

Ventricle position can be remodeled after heart looping! In a model of heterotaxy we uncovered a new asymmetric morphogenesis process during which the heart reorients its chambers. So grateful to all the authors for their expertise and input during this long (but fun) ride 💪 Read more here ⬇️

✨ Post-doc opportunity in axon biology, funded by #ATIP-Avenir! 👀 We are looking for an enthusiastic post-doc to join our team at @ibdm.bsky.social to explore translation dynamics in axon regrowth, using live imaging approaches. Apply at: emploi.cnrs.fr/Offres/CDD/U... Thank you for sharing! 👋 🙏

Thrilled to share our new paper: "OpenEMMU: A versatile, open-source EdU multiplexing methodology for studying DNA replication and cell cycle dynamics"! We've developed a new resource that make this crucial research more accessible, accurate, powerful and low-cost. www.cell.com/iscience/ful...

DUX4 at 25: how it emerged from “junk DNA” to become the cause of facioscapulohumeral muscular dystrophy skeletalmusclejournal.biomedcentral.com/articles/10.... #FSHD, #DUX4, #Myoblue #SkeletalMuscle

The HDAC inhibitor romidepsin renders liver cancer vulnerable to RTK targeting and immunologically active www.nature.com/articles/s41... Fantastic new paper from Flavio Maina, Celia Sequera, Margherita Grattarola and colleagues at the @crcm.bsky.social #CancerResearch, #CRCM, #LiverCancer

🧠 Position still opened! Don't hesitate to apply if you want to use human pluripotent stem cell based models to understand the evolution of human cerebellar neurons and disorders!

Neurotrophin-3 produced by motor neurons non-cell autonomously regulate the development of pre-motor interneurons in the developing spinal cord https://www.biorxiv.org/content/10.1101/2025.07.27.665825v1

Kicking off the lab BlueSky with this picture of a happy hairy growing #axon! Looking forward to connecting with science chats and to growing research ideas 🧠🔬✨

SARCOMERES divide! Mechanism how muscles grow while contracting - daughter sarcomeres appear everywhere. Seen live, registered on our cover. Pioneered by @clementrodier.bsky.social @friedrich-group.bsky.social Ian Estabrook @ibdm.bsky.social $ by @hfspo.bsky.social www.science.org/doi/10.1126/...

🚨 PLF : Les préconisations de l’IGF/IGESR menacent directement notre santé et celle de nos enfants ! 📣 Les principales fondations et associations de recherche biomédicale expriment leur profonde inquiétude bit.ly/44u3aSR

Postdoc🚨! Come join our HFSP team to uncover how chromatin moves in cells and what this means for genome function! Great opportunity to combine single-cell genomics, live imaging and polymer physics in the unique mammalian retina with @andersshansen.bsky.social, Davide Michieletto & Sandra Tenreiro

Textbooks: “Enhancers are just a bunch of TFBSs” But how do they REALLY work? New paper with many contributors here @berkeleylab.lbl.gov, @anshulkundaje.bsky.social, @anusri.bsky.social A 🧵 (1/n) Free access link: rdcu.be/erD22

The amazing organization team of #ShapingLife3 meeting of @sfbd.bsky.social in sunny Cassis! Thanks to the great scientists for sharing their passion for embryos, and the beauty of life ! @maitrejl.bsky.social @cedricmaurange.bsky.social @maevalux.bsky.social @ibdm.bsky.social and others

The tumor suppressor FAT1 controls YAP/TAZ protein degradation and tumor cell proliferation through E3 ligase MIB2 journals.plos.org/plosone/arti... This work from Rui Li, Stefan Offermanns, and colleagues, extends the role of this FAT1-MIB2-YAP axis to the control of tumour growth

Do you want to join us to work in neurodevelopmental biology? Please apply 👇 #SEBD

Postdoc in Computational Biology – Auditory Pathways & Sensory Disorders @LallemendLab to study how peripheral/central auditory pathways (circuit, cellular, molecular) are altered in tinnitus & age-related hearing loss. #scRNAseq, #barcode-lineage-tracing, #translational ki.varbi.com/what:job/job...

Transcriptional and cellular maturation of the chick spinal cord in the context of distinct neuromuscular circuits www.biorxiv.org/content/10.1... Beautiful new preprint from the Tschopp lab

Very excited to share our latest work revealing a prominent role for LADs in commisioning cell fates in mouse organ & tissue development, particularly of the limb. Amazing work by Isabel and Samy together with @stemundi.bsky.social & @drmrobson.bsky.social www.biorxiv.org/content/10.1...

In the battle against brain disease, researchers can now rely on a new arsenal of genetic tools – The Armamentarium. Together with scientists from across the NIH BRAIN Initiative, we’ve created and published over 1000 new enhancer AAV vectors. 🧠📈

One thousand candidate enhancers tested in vivo in the mouse brain! A massive resource and oh so useful as validation set for genome-wide enhancer prediction methods. Super fun to be involved in one of the papers: ‘the prediction challenge paper’ by Nelson&Niklas et al www.cell.com/cell-genomic...

Check out the neuroview and all the great articles of new tools to target different cell types with enhancer-mediated AAVs!

Congrats @frankschnorrer.bsky.social‬ and all involved ! Beautiful work ! 👏🎉

Fat cadherin cleavage releases a transcriptionally active nuclear fragment to regulate target gene expression. New preprint from Helen McNeill and colleagues doi.org/10.1101/2025...

New lab paper out! 😀 We describe a new benchtop technique to isolate microRNAs from various cell types in a complex tissue (like the developing CNS). This is a fruitful collab with the Cremer lab from @ibdm.bsky.social journals.plos.org/plosgenetics... 1/n 🧵

Congrats to @columbiauniversity.bsky.social scientists Gary Struhl & Iva Greenwald for winning the @gairdnerawards.bsky.social Award for their research yielding critical insights on how cells communicate with their neighbors during development. Read: zuckermaninstitute.columbia.edu/columbia-gai...

🚨 Save the date 🚨 🧬 Shaping Life 3 is back!  📆 Join us June 3-6, 2025, in Cassis, France, for cutting-edge talks on stem cells, morphogenesis, gene regulation & more! 🌊 Organized by @sfbd.bsky.social & IBDM at the stunning Oustau Calendal. More info 👇

Out in this month's issue of Aging Cell. Motor neurons do better in the presence of primary human muscle cells from older exercisers vs non-exercisers. 🙏to @lundbeckfonden.bsky.social for the Ascending Investigator grant 4 years ago to see this work through doi.org/10.1111/acel...

If you’re curious about why lymphatic endothelial cells have their jigsaw puzzle-like shape, check out our paper @Nature rdcu.be/eejhZ

Excited to share that the preprint of my Ph.D. work is now available! 🎉 Huge thanks to my amazing co-authors for their support and collaboration: @gaellel.bsky.social, H. Varet, V. Laville, J. Fernandes, @tajbakhshlab.bsky.social, @brendan-evano.bsky.social. @devstempasteur.bsky.social @pasteur.fr

Do not miss this great opportunity to present your work to the Neuroscience community in a stimulating and friendly environment 🤗 We are looking forward to welcome you in our beautiful and vibrant city of #Montpellier! See you soon @socneuro.bsky.social @fens.org @inserm.fr @cnrs.fr

The Editors-in-Chief of the 5 @biologists.bsky.social journals have written a joint Editorial, discussing the enormous challenges currently facing researchers in the US and how members of the community can support them through this difficult time journals.biologists.com/jeb/article/...

Excited to share today, a whole new chapter in my scientific journey. TAPELab( @christophertape.bsky.social) latest review on ‘High-dimensional signalling analysis of organoids’ is now online. Full review available here: www.sciencedirect.com/science/arti...

Derivation and analysis of human somatic sensory neuron subtypes facilitated through fluorescent hPSC reporters www.biorxiv.org/content/10.1... Fantastic preprint from Joriene de Nooij and colleagues

Please repost - some places available for students who desire to learn all about stem cells, and then some, in a great environment with leading experts in the respective fields.

Spatial transcriptomics in fly brain and body. Wonderful collaboration with @steinaerts.bsky.social led by @jasperjanssens.bsky.social @pierremangeol.bsky.social Nikolai Hecker & Gabriele Partel - look at mRNA patterns in muscles and brains spatialfly.aertslab.org elifesciences.org/reviewed-pre...

🇪🇺 👉Increased muscle satellite cell content and preserved telomere length in response to combined exercise training in patients with #FSHD 💡These findings suggest that such training supports muscle regeneration without accelerating cellular aging. t.co/yLMeTn0rsy

mitoXplorer 3.0 has been published in the JMB issue 'Computational Resources': doi.org/10.1016/j.jm... Check out our web-tool to analyse bulk- and single-cell RNA-seq data from a mitochondrial perspective. mitoxplorer3.ibdm.univ-amu.fr

Another amazing milestone from Flavio Maina & Colleagues Floriane Cannet and Celia Sequera et al. 🎉👏 ! Tracing specificity of immune landscape remodelling associated with distinct anticancer treatments: iScience www.cell.com/iscience/ful... @crcm.bsky.social @borgjp.bsky.social