Fantastic insights on how replication stress drives cell differentiation by Osvaldo Contreras at the joint meeting of the #InSDB and International Society of Differentiation #ISD joint meeting at #IISER_BERHAMPUR @osvaldoics.bsky.social #INSDBISD2025

Star #Scientist @osvaldoics.bsky.socia is uncovering how hearts grow - and what goes wrong when they don’t. He's mapping the molecular ‘blueprint’ of heart cells to uncover the mechanisms that could one day help damaged hearts repair themselves:

Thank you for the highlight @ishr-aus.bsky.social 🙏🏼❤️

New @natcomms.nature.com paper today from Tracy Bryan's lab @cmri.bsky.social: "Nuclear actin and DNA replication stress regulate telomere maintenance by telomerase". Happy our lab could play a small part. Congrats Tracy, Ash Harman, Noa Lamm and the whole team. www.nature.com/articles/s41...

💡Dr Osvaldo Contreras’s funds will allow for open access publication of “OpenEMMU: A versatile, open-source EdU multiplexing methodology for studying DNA replication and cell cycle dynamics” in iScience.

“There were some cells in there that were very messed up” In a technological tour-de-force, researchers have sequenced the whole genomes of more than 100 individual cells from one 74-year-old man go.nature.com/44yj4MN

In vivo differentiation of embryonic cells devoid of key reprogramming factors

One week left to register! Join the Editors-in-Chief of Differentiation on November 14 at 12:00 p.m. Central for a virtual seminar with Pavani P. Perera on the enteric nervous system, evolution, and cave fish. Register for free: https://bit.ly/4oaU71P Topic: https://bit.ly/478UZhu

Save the date! @isscr.org, @alleninstitute.org & @socdevbio.bsky.social are collaborating to present a 3-day scientific symposium led by early-career scientists. The Stem Cell & Developmental Biology Early Career Symposium will be held September 23-25, 2026 in Seattle, WA. Learn more: bit.ly/4p98dkv

Catch up on the recordings from our October #DevPres webinar on development across scales. View the presentations from @osvaldoics.bsky.social and @yinanwan.bsky.social. thenode.biologists.com/catch-up-on-...

Transitions is the newest in our series of stem cell conversations. Launched by Ritika Saxena, Jarmon Lees and @osvaldoics.bsky.social we explore project and career transitions. All the parts needed for successful science that don't make it to the bench. For Aussie scientists, but all welcome.

We are celebrating 5 years of the Australia stem cell conversation! Hosted by @unimelb.bsky.social and @asscr.bsky.social the stem cell conversation is a weekly 30min virtual seminar series organised by EMCR for EMCR. Join the first 'transitions' episode Leadership through Service: 11am AEST Wed.

I’m very excited to be invited to present at “Development Presents…” Thanks @amjeve.bsky.social

Remarkable conference organized by @asbmbaus.bsky.social up in Brisbane at the University of Queensland. I was invited to present my latest work as a Keynote Speaker for the Multi-Sonic’s session, and so many thanks for selecting me! Truly an honour!

SAVE THE DATE! Join us for the 2025 @anzscdb.bsky.social NSW Branch Cell & Developmental Biology Symposium at the Garvan Institute @garvaninstitute.bsky.social on Wed 5 Nov 2025. Keynote speakers include Dougall Norris, @katequinlan.bsky.social, Silvia Velasco and @ryanlister.bsky.social 🔬🧠🧫

Honored to present at @ramacgenomics.bsky.social @unsw.edu.au next Tuesday.😃

Don't miss @osvaldoics.bsky.social in the flesh next Tuesday in Sydney

We're proud to share Dr Osvaldo Contreras has been awarded a Scale Biosciences Core Lab Grant, from @garvaninstitute.bsky.social Genomics Platform, Scale Biosciences, and Integrated Sciences to further his research into the origins of congenital heart disease that affects one in 100 babies.

Thrilled to share our new paper: "OpenEMMU: A versatile, open-source EdU multiplexing methodology for studying DNA replication and cell cycle dynamics"! We've developed a new resource that make this crucial research more accessible, accurate, powerful and low-cost. www.cell.com/iscience/ful...

1/n Very excited to share our recent paper published on @ScienceAdvances where we dissect the gene regulatory landscape guiding mouse sex determination! science.org/doi/10.1126/... A huge well done to @IsabelleStevant.genomic.social.ap.brid.gy, Meshi and Elisheva who spearhead this project!

If you love Daniocell, but wish it could generate analyses specific to YOUR genes & cell types of interest, check out DaniocellDesktop - a new point-and-click app for Mac and Windows that enables reanalysis of the Daniocell data without programming: daniocell.nichd.nih.gov/desktop/ (1/4)

www.science.org/doi/10.1126/... Worth reading

What’s potentially the first multi-omics study out there? Find it below. This represents a major step forward into what’s later defined as personalised medicine. Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes: Cell www.cell.com/cell/fulltex...

So happy about presenting our Pan-Omics work next week!🎉 Thanks for the invite👨🏽‍🔬🙏🏽❤️

📢 Today! National Stem Cell Conversations 🔬 Regulation of Patterning Qi Zhang: "Molecular mechanisms of epigenetic regulation" Adrienne Sullivan: "Early GATA3 activity mediates lineage commitment and patterning in human gastrulation" 📅 Wednesday, 7th May 2025 ⏰ Time: 11:00 AM - 11:30 AM AEST

www.science.org/doi/10.1126/... Fantastic technological progress!

FACS-assisted separation of cells for untargeted proteomics. Working with 10,000 cells per experiment to reveal the proteome of these, using low-input omics👨🏽‍🔬🔭 Thanks to all who make our research possible 🙏🏽✨ @victorchang.edu.au @garvaninstitute.bsky.social

A Piece of Art! A simple 2.5% Agarose gel with so much information in it. Fundamental science blows my mind, always 🤯❤️

Third paper submitted of the year 🎉 Extremely grateful to my team and colleagues for the daily fundamental discoveries that pave the way for impact and translation 🙏🏽 Fingers crossed for their consideration and smooth revisions

🚀 Open Science can’t wait! I’m thrilled to share our latest preprint: 𝐎𝐩𝐞𝐧𝐄𝐌𝐌𝐔! 🔬 𝐎𝐩𝐞𝐧𝐄𝐌𝐌𝐔: A versatile, open-source EdU multiplexing methodology for understanding DNA replication and cell cycle dynamics 🔗 Read the preprint here: biorxiv.org/content/10.1... #OpenEMMU #DNAReplication #CellCycle

🚀 Open Science can’t wait! I’m thrilled to share our latest preprint: 𝐎𝐩𝐞𝐧𝐄𝐌𝐌𝐔! 🔬 𝐎𝐩𝐞𝐧𝐄𝐌𝐌𝐔: A versatile, open-source EdU multiplexing methodology for understanding DNA replication and cell cycle dynamics 🔗 Read the preprint here: biorxiv.org/content/10.1... #OpenEMMU #DNAReplication #CellCycle

Fascinating paper! No G2/M checkpoint for under-replicated cells! academic.oup.com/nar/article/...

Today in Science Advances: "Chromatin Conformation, Gene Transcription, and Nucleosome Remodeling as an Emergent System" in which CPGE researchers demonstrate that the human genome is an emergent, self-assembling, reinforcement learning system. #chromatin #genomics www.science.org/doi/10.1126/...

Light can influence metabolism independent of the circadian clock, according to a new #ScienceAdvances study in mice. Learn more: scim.ag/3DIu7bP

Grateful for our collaboration with @sarah_e_hancock & Nigel Turner's Lab! 🎉 Proud to have contributed my expertise in lipid droplet biogenesis to this study💡 "Targeting de novo lipogenesis improves gemcitabine efficacy in pancreatic ductal adenocarcinoma" www.biorxiv.org/content/10.1...

Thrilled to share my contribution to the December issue of the Australian Biochemist! In this issue, we reflect on the enriching experience of participating in the Young Scientist Program 2024 (#YSP2024) at Biomolecular Horizons. 🔗 Read more here: lnkd.in/gbA7Hf_E

Collaboration & co-creation aren't the same thing. If we want to do things differently in future, collaboration (working with others who might not share our goals) isn't enough. People need to be near the creation process (co-creation) to work in creative ways. lnkd.in/gA2sB4Z9. By Dennis Hambeukers