great.

I'm raising money for Breakthrough T1D (new name for JDRF) to change the lives of people with type 1 diabetes. We appreciate any support. This funding aids T1D research, which is even more important now with the uncertainty surrounding traditional research funding mechanisms. p.bt1d.org/7ujvl

I helped explain to the Chicago Tribune the enourmous and irrational damage the NIH funding freeze is causing at Northwestern. “You’re at risk of losing an entire next generation of scientists" "it’s terrifying; it’s completely senseless." www.chicagotribune.com/2025/06/07/w...

Actin remodeling in beta cells adds new layers of upstream regulation - Congrats! @ronnyhelman.bsky.social

Science is under attack. Proposed 40% NIH cut threatens jobs, research, and medical progress. Call your reps, governor, and mayor now—urge them to stand up for science. www.ascb.org/science-poli...

take a metal break www.youtube.com/watch?v=e2ms...

Paradoxically, both GIPR agonism and antagonism potentiate weight loss when paired with GLP-1R agonism. Two new studies in @natmetabolism.nature.com decode the different neural mechanisms employed by each strategy. Check out the #News&Views by @adriaenssenslab.bsky.social here.

The notice and COMMENT PERIOD OPENED TODAY AND CLOSES MAY 23. Anyone who would like to register an objection or comment should go to this page and click on the green “public comment” button at the top: www.federalregister.gov/documents/20... 6/n

NIH is the best investment there is. www.forbes.com/sites/michae...

Just posting this starter pack for #PancSky again as I have added more people - let me know any other islet/pancreas scientists I've missed! go.bsky.app/3wdSpdi

Hey #PancSky and #islet people, we're hosting the 2025 Midwest Islet Club in Indianapolis May 7-8. Most of the talks are from students/postdocs. Help spread the word about abstract submission and registration! medicine.iu.edu/research-cen...

Breaking: FDA's March meeting to select flu shot strains for 2025-2026 season has been canceled per email sent to committee members, a VRBPAC member told me. drug companies need about 6 months leeway to make shots in time for fall vax campaigns. #healthpolicy

Join us! Science Homecoming helps scientists reconnect with communities by writing about the importance of science funding in their hometown newspapers. We’ve mapped every small newspaper in the U.S. and provide resources to get you started. Help science get back home 🧪🔬🧬 🏠 sciencehomecoming.com

The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.

Ok scientists & those who love science 🧪: here is another exhortation. Call Congress TODAY about the freeze on NIH Council Meetings and Study Sections. Emphasize that this means NO new grants are being funded & labs will soon start to shut down and fire employees. Phone numbers are at: 5calls.org

I've been developing a semantic search tool that covers not just bioRxiv and medRxiv, but the entire PubMed database. This means you can search across a massive collection of biomedical research using keywords, questions, hypotheses, or even full abstracts. Try it out: mssearch.xyz

I don't think IIDP is on Bluesky yet, so just reposting. iidp.coh.org/funding Applications Due: February 14, 2025. #islet #PancSky

Reminder: You can always submit a grant late and include a cover letter saying why. NIH receipt and referral may take it. Or not. If you end up missing deadline because of these Commons access issues, there is this potential save move.

New preprint from the lab! 🚨 🧫 New galactose #CRISPR screening strategy 🎯 481 genes required for #OXPHOS ⚙️ #FAM136A in IMS proteostasis 👂Mito defects in #Menieres disease by @marcellharhai.bsky.social @fbm-unil.bsky.social A short thread 1/5 www.biorxiv.org/content/10.1...

"Of Wolf and Man" by Metallica x "Fifflas" by C418

Will be very interesting to see how molecular biology changes in the next decade with these types of advances.

Re-upping this paper which is ‘out’ now in this month’s issue of Cell Metab. Working with a fantastic group of collaborators, we provide a resource for exploring human islet variation in health and diabetes. https://www.cell.com/cell-metabolism/fulltext/S1550-4131(24)00365-6

Wow!

Happy to finally have this preprint up which represents a lot of effort from first author Gitanjali Roy and important contributions from multiple labs. I hope this work enables the discovery of cool beta cell biology related to hypersecretion.

Nurd-metal youtu.be/4Uwy6-LuCF8?...

Starter packs are still valuable but there is now a mature set of communities @bsky.app So maybe for the last time (unless things change) An encyclopaedia of starter packs relevant to 'mechanistic' biomedical science (>100 now!)... ...including collective nouns docs.google.com/spreadsheets...

Check out also @timwrhoads.bsky.social 's go.bsky.app/C2t7snh and @frezzalab.bsky.social 's go.bsky.app/VavECSX

Our undergrad interns in my lab at IBRI, Rachel Kuntz (#UROP) and Ini Aduroshakin (#LHSI), presented a few weeks back at the Indiana University Indianapolis Undergrad Research Conference! Rachel won an honorable mention for her poster! Thanks Andrea John and Tom Stucky for organizing.

Nobel Laureates Urge Senate to Turn Down Kennedy’s Nomination Elevating Mr. Kennedy to secretary of H.H.S. “would put the public’s health in jeopardy,” more than 75 laureates wrote. www.nytimes.com/2024/12/09/h...

this band keeps getting more badass with every passing year. #bloodywood youtu.be/skXlKxjlUoo?...

Went with NY strip roast this year as a turkey/ham alternate. Great idea! #reversesear

My one constructive criticism on BlueSky, as a community: we need to “like” less and “retweet” more. In the absence of an algorithm, that’s the way we find each other and reward good content.

Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”. doi.org/10.1038/s422... A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social

www.cell.com/cell/fulltex... Looks like an interesting resource

Please lower your voice while speaking with me - youtu.be/kivUsDGWojU?...

The new Coheed singles are sounding pretty good - www.youtube.com/watch?v=hDsY...

Another interesting story by Peter Draber and team. #celldeath rdcu.be/d00nb

Interesting - you can bridge your Bluesky account with the fediverse (aka what Mastadon uses) by following @ap.brid.gy It takes a few hours to kick in. To follow users on Mastadon, they must also have the bridge enabled though. Additional info: fed.brid.gy/docs

go.bsky.app/HU7e761 @mattoolab.bsky.social done !!!!

Waves of new BlueSky arrivals in last few days! I’ve been tracking starter packs relevant to molecular/mechanistic/genetic/cellular…etc biology Hope it’s helpful but warning: now a v long thread! Probably the last time I can do this...

go.bsky.app/3wdSpdi It can be difficult to recreate your following list here, please comment/tag any other islet/panc people I am missing and I will edit the pack.