154 million lives and counting: 5 charts reveal the power of vaccines. Story by @heidiledford.bsky.social www.nature.com/articles/d41...

Safeguarding immunisation: a core function of WHO - The Lancet www.thelancet.com/journals/lan...

Microplastics are facilitating antibiotic resistance journals.asm.org/doi/epub/10.... open-access

Not only does Bennu contain all 5 of the nucleobases that form DNA and RNA on Earth and 14 of the 20 amino acids found in known proteins, the asteroid’s amino acids hold a surprise https://go.nature.com/4hDtGhL

Our latest editorial is now online, in advance of our February issue that will be available next week. Brain microbiome: is it all in our heads? www.thelancet.com/journals/lan...

#CLRpower! Sensing of microbiota after gut barrier disruption reprograms the bone marrow & myeloid functions via the C-type lectin receptor Mincle!! @cp-immunitt.bsky.social from @sancholab.bsky.social &co! 👇👇👇

But, who is sensing E. faecalis? We found that Mincle is sensing E. faecalis and that Mincle mediates trained immunity in response to their many ligands. Staphylococcus aureus, another bacteria translocated to the BM, is also sensed and inducing trained immunity via Mincle.

New paper alert 📢! (Cell) @cp-cell.bsky.social - How does immune responses to solid tumors vary by age and tumor characteristics in children?! www.cell.com/cell/fulltex... 🧵1/8

Polysialic acids are upregulated on activated T cells #glycotime

#InterferonPower! Khan Tran Divanghai &co show @natimmunol.bsky.social that systemic fungal b-glucan administration potentates granulopoieis via type I IFNs (not IL1!) driving IL10-producing neutrophils that protect against lung influenza A virus infection increasing immune tolerance, not resistance

Five years ago, on 31 December 2019, WHO’s Country Office in #China picked up a media statement by the Wuhan Municipal Health Commission from their website on cases of ‘viral pneumonia’ in Wuhan, China. 🧵

Global immunization efforts have saved an estimated 154 million lives – that is 6 lives every minute – since the founding of the Expanded Programme on Immunization, 50 years ago. bit.ly/4gpxQJK

"Collectively, these results demonstrate the ability of the innate and adaptive immune systems to recognize chlorovirus glycoproteins, a process dependent on their specific N-glycan structures..." Our #glycotime study just published @commsbio.bsky.social www.nature.com/articles/s42...

Valerie Lensch of @kiesslinglab.bsky.social and the Johnson group reviewed different glycan-based strategies for eliciting an immune response: academic.oup.com/glycob/artic... #glycotime

New 🚨 #glycotime in @science.org H5N1 "a Gln226Leu substitution switched Texas HA binding specificity to human-type receptors, which was enhanced when combined with an Asn224Lys mutation" ⬇️⬇️ www.science.org/doi/10.1126/...

The danger theory of immunity strikes back... rdcu.be/d1uQN

This month in #ScienceImmunology, @virusesimmunity.bsky.social & colleagues reported that #ERV -reactive #B1Cells secrete #antibodies that recognize GlcNAc moieties on both ERV #glycoproteins as well as glycoproteins of other enveloped #viruses!