Research led by Tomasz Nowakowski, PhD @ucsanfrancisco.bsky.social @ucsfstemcell.bsky.social in @nature.com | New map of fetal brain cell development may change our understanding of mental illness and cancer www.earth.com/news/new-map... #UCSFProud

Peng He & colleagues published “Toward informed batch correction for single-cell transcriptome integration” in Nature Computational Science. They review current data cleaning methods & envision interpretable frameworks that model technical + biological variation in single-cell data: rdcu.be/e4cSp

15 years ago today, @ucsanfrancisco.bsky.social celebrated the opening of the Ray & Dagmar Dolby Regeneration Medicine Building on our Parnassus campus. Take a look back at scenes from opening day and move-in, and see what our researchers are working on today: stemcell.ucsf.edu/2024-2025-uc...

The UCSF Broad Stem Cell Center and Department of Surgery invite applications for a new faculty position focused on the development of delivery tools for gene editing to enable cutting-edge gene therapies. Please share and apply 🔗 aprecruit.ucsf.edu/JPF05914

Nature research paper: Dissecting gene regulatory networks governing human cortical cell fate go.nature.com/4qBG5rp

Researchers in Diana Laird's lab discovered the decline in female fertility w/age isn’t driven solely by eggs; other cells in the ovary, including glia and fibroblasts, influence ovarian health & aging—part of UC’s top discoveries of 2025. #UCSFProud www.universityofcalifornia.edu/news/10-awes...

Kyle Cromer's team published collaborative work with Stanford in @bloodadvances.bsky.social using CRISPR tools to create a mouse model of a rare juvenile leukemia. Congrats to Roshani Sinha, Devesh Sharma, & Benjamin Lesch for co-authoring this publication. More: ashpublications.org/bloodadvance...

Our new manuscript, led by Emily Corrigan, examines inhibitory neuron diversity across approximately 160 million years of evolutionary divergence, as part of BRAIN Initiative Cell Atlas Network (BICAN) developing brain atlas package: www.nature.com/articles/s41...

Happening TODAY! Tune in at noon for #UCSFSOTU 2025 with Chancellor Sam Hawgood. Hear about UCSF’s accomplishments from the past year and how our institution is innovating to adapt for the future. tiny.ucsf.edu/HuBTYF

New issue of Nature - with NINE studies on #brain #development from the BRAIN Initiative Cell Atlas Network (BICAN) 🧠🧪🔬 An amazing set of resources for all scientists working on the brain! 🧠 Immersive feature: www.nature.com/immersive/d4... 🧠 Perspective: www.nature.com/articles/s41...

The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor. The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2. www.leadingedgesymposium.org/apply/

We love this!! ❤️ #UCSFProud

Happy World CRISPR Day! The CRISPR revolution began with genome editing, but the platform has evolved into a versatile molecular toolkit with wide-ranging applications. The current issue of TiG includes a Review of these applications. Check it out! www.cell.com/trends/genet...

Join us today, 10/16, for Getting to Patients! Dr. Claire Clelland will share “Developing CRISPR gene therapy for C9orf72 FTD/ALS: the path ahead to clinic” with Special Guests and perspectives from a family with the C9orf72 gene tiny.ucsf.edu/14kshU @ucsfsurgery.bsky.social

Congrats to Kyle Cromer, PhD, on receiving an NIH Director’s New Innovator Award! Dr. Cromer is working on better treatments for sickle cell disease by trying to help the bone marrow produce more healthy red blood cells. 🧬 #UCSFProud www.ucsf.edu/news/2025/10...

A new imaging technique and single-cell sequencing reveal a deeper understanding of ovarian aging. @ucsanfrancisco.bsky.social & @czbiohub.bsky.social study could be key to strategies for extended fertility and healthier aging. www.ucsf.edu/news/2025/10...

For #StemCellAwarenessDay, a look at a human neuron grown from stem cells, captured by Dr. Yonatan Perez, a Kriegstein Lab postdoc alum. This work could inform therapies for neurological disorders and brain regeneration.

Congratulations to our Broad Center members (Bruce Conklin, Tippi MacKenzie, Jingjing Li, Benoit Bruneau, and Holger Willenbring) and colleagues on their newly awarded CIRM Discovery (DISC0) grants!

From cloudy mornings to golden sunsets—the UCSF Broad Stem Cell Center always has a view worth sharing. 🌿☀️ Thanks to Lael and Cassie from the IRM Admin Team for these shots! #UCSF #Dolby #KarlTheFog #OfficeViews #CampusViews #GoldenHour

Congratulations, Tomasz Nowakowski, PhD! 🧬🧠✨ #UCSFProud

The University of California provides transformative educational opportunities, life-saving health care and research that moves our state forward and powers our economy. Stand with UC for the future of California: bit.ly/46LvcMo youtu.be/OpvhTJtxF5o?...

Congrats to Lilian Gomes de Oliveira, PhD, who joins the 2025 class of Pew scholars and fellows! As a Pew Latin American Fellow, Lilian will explore how the Zika virus disrupts cerebral cortex development during the second trimester of pregnancy. Learn More: www.pew.org/en/about/new...

New from the Cromer Lab detailing methods for achieving high-efficiency CRISPR-based genome editing in primary hematopoietic stem and progenitor cells (HSPCs). Discover more @cp-starprotocols.bsky.social | star-protocols.cell.com/protocols/4394

So proud of Kaylee who won a #GordonConference Travel Award! 🥇 🤩 Congrats to @brisapalikuqilab.bsky.social for a fantastic #GRS and Profs Karina Yaniv and Anne Eichmann for an outstanding #Angiogenesis conference @ucsfchildrens.bsky.social @ucsfstemcell.bsky.social

Congratulations, Jaela Caston and @elizabethcrouch.bsky.social!! We’re #UCSFProud to celebrate you as 2025 Gilliam Fellow & Advisor 🎉 @ucsanfrancisco.bsky.social www.hhmi.org/programs/gil...

🧬 The gene therapy landscape for sickle cell is evolving—join the UCSF Sickle Cell Center of Excellence for a powerful virtual town hall with Dr. Mark Walters, an expert in sickle cell and cell/gene therapy. This session is perfect for patients, caregivers, healthcare professionals, and advocates.

Thank you to all the incredible trainees, program directors, patient advocates, and inspiring speakers who joined us for the 2025 #CIRMTraineeConference! We’re grateful for the insights you shared and the community we continue to build together in advancing #RegenerativeMedicine. #BlueskyBiotech

New in @natneuro.nature.com: Astrocyte fate isn’t hardwired — it’s shaped by where they grow up. Local neuron signals — not just where they come from — shape their identity. A key step toward understanding brain health and developing new therapies. rdcu.be/eyoIX #NewResearch

🎧 Don’t miss this podcast with Dr. Tippi MacKenzie, Broad Center Director, on in utero therapies & the future of regenerative medicine. 📍19:40: vision for the Center → discover, engineer, heal. 🔗 bit.ly/46qjYgi #UCSF #StemCells #FetalSurgery #GeneTherapy #GenomeEditing #DiscoverEngineerHeal

Did you know that the illustrations in our resources like CRISPRpedia are free to use for non-commercial, educational purposes? Check out our Science x Art page to see a selection of work from our designers & artists. Tag us to show us how you're using them! innovativegenomics.org/science-x-art/ 🧬🎨

It's #WorldBrainDay! The brain controls everything that makes life possible. Scientific research provides the tools and knowledge needed to protect, restore, and enhance brain health for all. Are you a #neurowiz? Take this short quiz to find out: vist.ly/3yr5j

Why Is Discovery Research So Important? Broad Center member Grae Davis unpacks how big breakthroughs happen and why public understanding of science matters: magazine.ucsf.edu/why-discover...

A full circle ⭕️ moment interviewing @ameliecollins79 . Dr. Collins was my fellow during my #neonatology sub-I. Fascinating #hsc work (the mother cell of #immunology!) ✅it out and her 😍publication: pubmed.ncbi.nlm.nih.gov/38428422/ @ucsfchildrens.bsky.social @ucsfstemcell.bsky.social

🚨 REMINDER: Prospective DISC4 applicants, the Pre-Submission Form deadline is June 16 at 2 PM. The DISC4 Awards support large, cross-disciplinary teams working on innovative ways to understand and treat human disease. Learn more at www.cirm.ca.gov/disc4/.

We are thrilled that @semilc.bsky.social and the Choksi Lab will be part of our RMB community! 🎉

🔊 TOMORROW, June 5: Join @fda.gov’s Cell and Gene Therapy Roundtable featuring ASGCT Board Members Terry Flotte, Paula Cannon, and more, on the panel! Watch on YouTube from 9 a.m. to noon (ET). Do not miss out on this opportunity to hear from top regulatory leaders! www.fda.gov/vaccines-blo...

Today! Join us for our Getting to Patients seminar. Dr. Matthay will share “Allogeneic Bone Marrow-Derived Mesenchymal Stromal Cells for ARDS: Pre-Clinical and Clinical Data” with patient perspective and discussion moderated by Dr. Julia Brown tiny.ucsf.edu/StromalCells... @ucsfsurgery.bsky.social

CIRM is excited to announce that we have launched our new funding programs: the DISC4 (for multidisciplinary, collaborative basic #research), #Preclinical Development (PDEV), and #ClinicalTrial (CLIN2) Awards! Learn more about our funding programs on our website at www.cirm.ca.gov/researchers/...

The rapid advancement of CRISPR-Cas gene editing is transforming medicine, offering precise treatments for genetic disorders. Evaluating unintended effects remains crucial. UNCOVERseq, a new method, improves detection of off-target edits, enhancing the safety and effectiveness: bit.ly/UNCOVERseq

Hear how gene therapies can address serious genetic diseases before birth. Dr. Tippi MacKenzie will deliver a George Stamatoyannopoulos Memorial Lecture at the @asgct.bsky.social Annual Meeting on May 15. #ASGCT2025 #GeneTherapy #PrenatalResearch #raredisease

We love to see and hear this! ☀️ Thank you, @elizabethcrouch.bsky.social 😀

Join us today for Getting to Patients! — 4 PM in HSW-300

#cerebralorganoids 🧠🧫hold much promise in #neonatology but have yet to deliver directly for our #patients 👶🏾👶🏻 We outline some high yield areas for future study (vasculature! Cortical circuits!) @ucsfchildrens.bsky.social @ucsfstemcell.bsky.social ✅it out! journals.lww.com/co-pediatric...

So proud of #Crouchlab MSTP KWP (Kaylee Wedderburn-Pugh)! Come listen to her amazing talk on #bloodbrainbarrier gene modules during development @ucsfstemcell.bsky.social 🧠💻🧬 graduate.ucsf.edu/news/game-me...

Join us for Getting to Patients on Thurs, 3/20, in HSW-300! Drs. Peter Stock & Julie Sneddon share “Beta Cell Replacement Therapies for the Treatment of Diabetes Mellitus” with patient perspective and discussion with @juliaehbrown.bsky.social tiny.ucsf.edu/Diabetes

The incredible @rnahelix.bsky.social Dr. Carolyn Sangokoya and the formation of the Women’s physician scientists supergroup has had an incredible impact on my career! Great to see her celebrated! www.ucsf.edu/news/2025/03...

In @cp-cellreports.bsky.social, Arantxa Cebrian-Silla, PhD, Arturo Alvarez-Buylla, PhD, & their colleagues show that B2 cells are an important population of secondary neural stem cells that help sustain neurogenesis in adult mice: doi.org/10.1016/j.ce... @ucsfstemcell.bsky.social #Neuroskyence

Celebrating International Women's Day 2025 at UCSF this week with a fabulous group of panelists Women in Science: Holding the Vision in Academic Science and Medicine March 7th 3pm PST shorturl.at/rVrdt

We’re excited to share that Dr. Kyle Cromer was featured on the “People Behind the Science” podcast! Tune in to hear his insights on gene editing, innovative cell therapies, and his scientific journey. Listen now: www.peoplebehindthescience.com/dr-kyle-crom...

Grateful to the Sontag Foundation for their support of brain tumor research at UCSF! We’re glad to be catching up with our colleagues and collaborators this week at the annual Sontag Scientific Retreat. @ucsfcancer.bsky.social @ucsfstemcell.bsky.social