With the ongoing #TB outbreak at an SF high school, we will leverage our expertise in child TB, with the @citc-tb.bsky.social and @ucsf-ctb.bsky.social. @ucsfchildrens.bsky.social is working closely with SF public health to support students and families. pediatrics.ucsf.edu/news/access-...

"Ethical research requires that participant safety remains central, not subordinate to hypothesis testing....Vulnerability should never be seen as an opportunity to advance research at the expense of those it claims to serve." @natureportfolio.nature.com www.nature.com/articles/d41...

Important and timely study Pregnant women face higher risks from Ebola: maternal mortality up to 89%, and nearly all pregnancies lost. Until now, they’ve been excluded from Ebola vaccine trials. A landmark phase 3 RCT in Rwanda changes [email protected] www.nature.com/articles/s41...

We should be able to agree that funding research for pediatric cancer should be prioritized and expanded. Not canceled. Clinical trials that can be the last hope for kids with cancer stopping recruitment due to funding loss is heartbreaking 💔 www.nytimes.com/2025/08/28/w...

🚨 NEW PUBLICATION 🚨 "Pregnancy and lactation induce distinct immune responses to #COVID19 booster vaccination and SARS-CoV-2 breakthrough infection" from the Roan Lab in @jci-insight.bsky.social

A team of scientists, led by Nadia Roan, found that pregnant and lactating women have strong immune defenses to COVID-19, and identified key benefits that could guide future vaccine design.

Study finds strong immune defenses in pregnant and lactating women, with key benefits that could guide future vaccine design.

🚨 NEW PUBLICATION 🚨 "Pregnancy and lactation induce distinct immune responses to COVID-19 booster vaccination and SARS-CoV-2 breakthrough infection" from the Roan Lab in @jci-insight.bsky.social

On a day that the congress has decided to go on an early recess and take 6 weeks of paid leave it is important to remember that in the U.S there is no federal law that guarantees paid maternity leave or family leave. Just something to think about in case you need more things to think about today.

Happy to share our new work @jci-insight.bsky.social insight.jci.org/articles/vie... When I was pregnant in Dec 2020, one of the many things that concerned me was if the COVID-19 vaccine would protect me as well as non-pregnant people, as I knew the high risk of COVID-19 infection in pregnancy (1/n)

🚨BREAKING: IDSA, along with AAP, APHA, ACP and others, has filed a lawsuit against HHS/Secretary Kennedy to stop unlawful changes to vaccine policy and defend public health. We refuse to stand by while America’s public health safeguards are torn apart. bit.ly/4lm7UkW

BREAKING: Six leading medical organizations filed a lawsuit on Monday against Robert F. Kennedy Jr., the health secretary, and the health dept, charging that recent decisions limiting access to vaccines were unscientific and harmful to the public. (Gift link) www.nytimes.com/2025/07/07/h...

Hepatitis B can be passed from parent to baby at birth - and when that happens, the consequences can be deadly. It is unscientific and dangerous to intentionally ignore the success of U.S. vaccination programs or argue that the U.S. should not vaccinate babies for hepatitis B at birth.

We now have presentations on COVID-19 vaccine effectiveness: www.cdc.gov/acip/downloa... These presentations can become very confusing so I need to explain a bit about them:

In case you needed another reason to hate Epstein-Barr virus- it looks like it might cause primary sclerosing cholangitis: www.nature.com/articles/s41...

New Publication: We conducted a multi-country prospective comparison of 3 methods for stool processing for Xpert Ultra testing for childhood TB, and found they performed similarly and were usable and acceptable by lab workers: academic.oup.com/cid/advance-.... @cidjournal.bsky.social #tbsky #idsky

You’re pregnant, healthy, and hearing mixed messages: RFK Jr. says you don’t need the covid vaccine, but experts at the CDC still put you in a high-risk group of people who ought to receive boosters. Here's what the science says. 👇 kffhealthnews.org/news/article...

When Americans raised concerns about RFK Jr.'s anti-vaccine views, he said he was "not gonna take away vaccines from anybody." But now he's taking them away from millions of mommas and babies. Vaccine recommendations should be based on science, not RFK Jr.'s political agenda.

ACOG is deeply disappointed by HHS’s move to drop COVID-19 vaccine recommendations in pregnancy. The science is clear: COVID-19 remains dangerous in pregnancy and vaccination protects both patients and newborns. The vaccine is safe and protects families. Read our full statement: buff.ly/OGue7sO

News on CDC's COVID-19 vaccine recommendation removed for pregnant women and children. #IDSky www.nbcnews.com/health/healt...

Pregnancy is a major risk factor for severe COVID-19 outcomes (read: death). GOP, if you want women to have more babies, how about making it easier for women to do that without dying?

This is one of the dumbest health policy decisions I have ever seen.

It's quite obvious RFK.Jr has been spared the trauma of seeing pregnant people intubated in the icu with severe covid infection fighting for the lives. Pregnancy is a risk factor for severe covid. Not recommending vaccines in pregnancy is reckless and unscientific. www.nbcnews.com/health/healt...

Makary and Prasad have a sounding board piece written in NEJM about the future of COVID-19 vaccine regulation at the FDA. Some thoughts:

My amazing colleague Dr. Victoria Chu highlighting the important work of CDC, and critical need for continued infectious disease support and funding. Helicopter rappelling is just one of many of her incredible accomplishments @ucsfchildrens.bsky.social www.washingtonpost.com/lifestyle/20...

There is overwhelming evidence that covid is associated w worse pregnancy outcomes and complications. There is evidence that children especially those w comorbidities benefit from covid vaccines. When shots are not recommended insurance can refuse to cover the cost. www.wsj.com/health/healt...

This decision is antithetical to public health. COVID-19 in pregnancy, particularly in the third trimester, is extremely dangerous and aside from the elderly infants younger than 6 months have the highest risk of hospitalization from COVID. They are critically dependent on maternal antibodies.

Breaking News: A baby with a rare disorder made medical history by receiving the first custom gene-editing treatment. The technique used has the potential to help people with thousands of other uncommon genetic diseases. nyti.ms/4j49xBy

We need new ways to classify TB severity in children. Our new paper in @jpidsociety.bsky.social shows a 3 gene signature that only requires a finger prick could be helpful for children with confirmed TB: doi.org/10.1093/jpid... #tuberculosis @ucsf-ctb.bsky.social @tb-innovation.bsky.social

#medsky #episky 🧪 #pedsky #idsky Here's why HHS's demand for all new vaccines to be approved by placebo-controlled trials is actually profoundly unethical and jeopardizes all vaccines requiring rapid updates to cover pathogens that evolve quickly open.substack.com/pub/deplatfo...

“The thing about malaria is that it resurges quickly” An unprecedented global effort had slashed malaria deaths, saving millions of lives. Now, however, that progress is unravelling. Frank Burkybile reports on a community in fear www.bmj.com/content/389/...

🧵1/N New study published in @jama.com on re-emergence of vaccine-eliminated infectious diseases under declining vaccination in the US. We model long-term risk and conditions for return to endemicity for measles, rubella, polio, & diphtheria. Collab w/ @Mathewkiang.com jamanetwork.com/journals/jam...

Review @natrevimmunol.bsky.social @vikilovesfacs.bsky.social Vaccination in pregnancy to protect the newborn www.nature.com/articles/s41...

Social media became a place of both solace and torment for the writer Amanda Hess, as she desperately searched for details about her child's rare birth syndrome. "How much of my son’s life would I share? Where did my identity end and his begin?"

#medsky #pedsky #immunosky #idsky #episky 🧪 It's come up again because of our FDA commissioner so let's talk about the neonatal dose of hepatitis B vaccine 🧵 First though, a bit about hepatitis B (HBV):

#medsky #pedsky #idsky ICYMI: some very heavy hitters in pediatric infectious diseases just recently wrote up review of how to recognize and manage measles and prevent outbreaks. publications.aap.org/pediatrics/a...

Check out our new publication on the accuracy of TB treatment decision algorithms for childhood TB in Uganda: journals.plos.org/globalpublic... #tbsky #tuberculosis #idsky

“the loss of U.S. support may mean 75 million children do not receive routine vaccinations in the next five years, with more than 1.2 million children dying as a result.” www.nytimes.com/2025/03/26/h...

“Gavi is estimated to have saved the lives of 19 million children since it was set up 25 years ago. The United States contributes 13 percent of its budget” www.nytimes.com/2025/03/26/h...

Not entirely shocked given the anti-vaccine people in leadership roles, but this could be truly devastating

This is devastating for the future of pediatric research

RFK Jr. has tapped a discredited researcher who once used leuprolide to chemically castrate autistic children based on a claim that this would address mercury toxicity that none of them had and is NOT treated by leuprolide to conduct a study of an association between vaccines and autism.

Okay I am doing this again. For the next 24 hours drop any infectious disease and/or vaccine -related questions below in response to this post and I will of my best to answer them. Responses are for information only not medical advice. #AskAnIDDoc March 2025 edition

WaPo article here, which is paywalled for me: www.washingtonpost.com/health/2025/...

I am so grateful for the reporters who are doing the work on telling the story of the incredible negative impact of the cessation of US aid. The human toll is hard to wrap one's head around. This article is a must read. www.nytimes.com/interactive/...

New viewpoint piece in JAMA concerning the early administration of MMR vaccine to children aged at least 6 months if they are at the site of a measles outbreak or traveling to one: jamanetwork.com/journals/jam... IMO:

Chilling read. USAID funding has a huge impact on saving lives of children across the world. The USAID clinics in East Africa I have worked in and visited have been incredible well-run centers of community health for preventing death due to HIV, malaria, TB, and vaccine related infections (1/3)

If you are the parent of 6-11 month old infant They might benefit from a bonus MMR dose now jamanetwork.com/journals/jam...

🧪 #medsky #pedsky #idsky Just want to clarify given the situation with measles: it is absolutely true that transplacental maternal antibodies are protective against measles (provided they exceed some threshold quantity) and breastfeeding does have many significant benefits, particularly in LMICs-

#medsky #idsky #pedsky 🧪 Our dear HHS Secretary has recently gone to claim that measles infection confers lifelong immunity whereas measles vaccination does not, among a number of other misleading or blatantly false things about measles. Let's look at the evidence 🧵