CIHR has launched a trial ballon that suggests shifting to one competition a year. This is the worst idea I have heard in a long time. The only benefit is making top-line success rates look better than they are. Keep it as is, do in-person reviews, and keep the pain in the open.

springer needs not to be our leadoff hitter. lost the jays the game. #bluejays

if ever a fanbase that shows up at >40K per home game deserved better...

#RIP Pierre Chambon (1931-2026) 1963 PARP 1970 RNA Pol II 1975 Nucleosome 1977 Split genes 1980 Promoter 1983 enhancer 1986 Nuclear receptor

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We’ve started an award for Best Lecture for the 2026 🇨🇦 National Grad Course in Islet Biology and Diabetes, voted on by the trainees (23 this year). The winners of the inaugural award [drum roll]..... @theodoreds.bsky.social and @chrisadoucette.bsky.social! Congratulations!

We had a masterclass today on the impact of human genetics in unraveling the mysteries of #T2D. Expert @annagloyn.bsky.social joined us to close out the 🇨🇦 National Graduate Course in Islet Biology and Diabetes for 2026!

Sorry, Cleveland #raps #jays 🇨🇦

Metabolism driving cell fate! TCA cycle rewiring underpins histone acetylation sourcing and cell-fate transitions during exit from naive pluripotency: Cell Stem Cell www.cell.com/cell-stem-ce...

Today in the 🇨🇦 National Grad Course in Islet Biology and Diabetes we are joined by experts @ejrideout.bsky.social and Jee Yeon Cha (Vanderbilt U) to discuss sex-dependent phenotypes and responses in chronic disease, autoimmunity, and diabetes. A dynamic lecture for a dynamic field!

All scientists are different but one thing that every successful scientist has in common is an intense, almost obsessive passion to know how things work... 1/2

link.springer.com/article/10.1... New targets for intervention in T1D

link.springer.com/article/10.1... New article from the group on the effects of aging and sex in beta cell glucose sensing - ROMO1 and complex II! Thanks to funders @diabetescanada.bsky.social and CIHR.

Today in the 🇨🇦 grad course in islet biology and diabetes we are joined by experts @rlhull-meichle.bsky.social and @teresamastracci.bsky.social for a discussion of context and cues: islets in a sea of acini!

Asked AI to draw an icon to represent the concept of "transplant". Stay in school, AI.

Tell me you've written a CIHR grant without telling me you've written a CIHR grant www.instagram.com/reel/DW9gCDN...

so this is what it's like having a starter go 7 innings #bluejays

A new step toward cures for type 1 diabetes in Canada. Breakthrough T1D Canada has formally asked the federal government to partner in launching the Breakthrough T1D Network for Canada (BTNC), a national effort to accelerate treatments for #T1D. 💙 Learn more 🔗 ow.ly/yi8850YH60L

Why, John Schneider, why?

new IAPP story from @bruceverchere.bsky.social

Congratulations Karen Maxwell, recipient of the 2026 Peter Gilgan Canada Gairdner Momentum Award. Full bio: www.gairdner.org/winner/karen... #2026GairdnerAwards

β-Cell adaptation to #metabolic stresses requires prolactin receptor signaling @apspublications.bsky.social @dream-diabetes.bsky.social journals.physiology.org/doi/full/10....

The #BlueJays have now struck out 47 batters in this series, the most by any team in the first three games of a season in MLB history (since 1900)

Joined today in the 🇨🇦 National Islet and Diabetes grad course by expert Yuval Dor to discuss the etiology of Type 1 Diabetes - viral infection or error of RNA editing?

Beta cell functionality drives response to interventions in T1D from @cevansmo.bsky.social and team

Very sad to hear of the passing today of our UCSF colleague Mike Bishop at the age of 90. A legendary and inspiring figure. He also led UCSF as Chancellor. Have a listen to his Nobel lecture. youtube.com/watch?v=CDv7...

Terrible umpiring makes us even more excited for ABS.

That is a bad strike three call on Juan Soto in the eighth inning. Shouldn’t happen period. Absolutely cannot happen in a game like this.

That game cannot end like that. A shame.

Sorting out the hairballs www.nature.com/articles/s41...

Incretin receptor masterclass today in the 🇨🇦 National Graduate Course in #islet biology and #diabetes from experts @daveyboyhod.bsky.social and @danieljdrucker.bsky.social from cell biology to translational impact #GLP1R #GIPR

FORZA ITALIA

Progress in science depends on new techniques, new discoveries, and new ideas, probably in that order. - Sydney Brenner

the latest on AI: 1. Language models are optimized for coherence, not truth The core objective during training is to produce text that is likely and coherent given the context. That objective does not directly encode a concept of factual truth. As a result, the system can produce [garbage]...

Today in the 🇨🇦 National grad course in #islet biology and #diabetes, experts Matt Merrins and Dick Kibbey from @yalepress.bsky.social stop by to discuss the latest in mechanisms of glucose coupling in the beta cell - it's all about the ATP! @utoronto.ca

Two cells isolated from a fish scale videoed through a DIC microscope. The cells are cool but now all I see are extracellular vesicles floating by in the media and stuck to the substrate....... #CellBiology

Beta cell stress in #T1D and #T2D with experts @bruceverchere.bsky.social @thompsonisletlab.bsky.social and @mathieuferron.bsky.social coming in today for the 🇨🇦 #Islet biology and #diabetes grad course @utoronto.ca - defining metrics for beta cell recovery

Thanks Rob! Super fun class as always! Good to see some familiar faces too

Today in the 🇨🇦 #Islet biology and #diabetes grad course we welcome experts @nkrentz.bsky.social and @drprentice.bsky.social who will discuss the pros and cons of common islet models as well as tissue crosstalk in #T1D and #T2D.

Join us in Toronto, July 13–16 for the inaugural International Conference on Neurogenesis & Repair! Featuring keynote Jeffrey Macklis (Harvard) + global speakers. 13 competitive short talks, poster sessions, and separate trainee awards. Early‑bird deadline: March 31.

Queued up in the 🇨🇦 National Graduate Course in #Islet Biology and #Diabetes today: experts @chrisadoucette.bsky.social and @theodoreds.bsky.social who will be discussing our current knowledge (and gaps!) on how #insulin actually gets out of a beta cell! Glucose coupling, circadian effects, and more!

🧬What if #betacells aren’t all the same? Professor Andrew Pospisilik shares new epigenetic evidence that could reshape our understanding of #diabetes and #heterogeneity - from beta cell subtypes to #obesity endotypes. 📺Watch now:🔗 easd-elearning.eu/episode/359/...

This week FRIDAY JAN23 at NOON CST we are thrilled to welcome @glim2016.bsky.social from @umontreal.ca @crchum.bsky.social to the pharmacology seminar series speak "Can we identify 14-3-3 zeta inhibitors to treat type 1 #diabetes" @dream-diabetes.bsky.social Join us Via ZOOM: 660 7073 7150 PW:594459

Today in the 🇨🇦 National Grad course in #Islet Biology and #Diabetes we welcome superstars Cristina Nostro and @yassiag.bsky.social to discuss the latest on using #stemcell derived islet cells as a strategy to treat (cure?) #T1D!

For ~century, we’ve asked: why do proliferating cells ferment glucose even when O2 is around? I’m thrilled to share our latest work @natmetabolism.nature.com, led by @thebiokimist.bsky.social. By leveraging conditional essentiality in HPLM, we propose a provocative new answer to this classic Q. 🧵

Will be discussing science communication today in the 🇨🇦 National #Islet and Diabetes graduate course - using the #betacell secretion coupling debate as a case study! @utoronto.ca

The 6th Annual 🇨🇦 National Graduate Course in #Islet Biology and #Diabetes hosted at @utoronto.ca kicks off today with 21 students and 30 outstanding lecturers from around the world. Today Drs. Wicklow and Gerstein will talk about #T2D and GDM in indigenous populations and the latest on #remission.

Study shows that neonatal #betacells sense gut microbiota-derived #bileacids via #FXR, limiting their development. Declining postnatal beta cell FXR expression allows normal neonatal beta cell growth and reduces #diabetes risk link.springer.com/article/10.1...

(please share) Immediate #postdoc job opening in the Millman lab at WashU Med (St. Louis, MO). Want to develop next-generation pancreatic islets for the study and treatment of diabetes? Email your CV to apply sites.wustl.edu/millmanlab/