Official posting coming soon, but here's a heads-up: #Postdoc Opportunity for individuals with an interest in advancing the understanding of pancreatic islet hormones in health and #diabetes. Diverse backgrounds, skill sets and experiences are welcome! www.bcell.org

Last week, Breakthrough T1D Canada had the privilege of co-hosting a workshop with Canada’s Stem Cell Network and Shift Health focused on a critical and complex topic:  "Unlocking Access for Type 1 Diabetes Cell Therapies in Canada: Identifying Solutions for Regulatory and Reimbursement Success."

‘Official’ results from the Vertex VX-880 trial using stem cell-derived islets for people with type 1 diabetes #T1D 10 out of 12 people with reduced or eliminated need for insulin 🎉 But note the need for immunosuppression and limited eligibility… this is not (YET) the ‘cure for everyone’

Excellent to see this Breakthrough T1D and CIHR-funded research by Dr. Mahmud at SickKids (Toronto) that shows improved glycemic control and kidney function when using the drug dapagliflozin in youth. Exciting to see research progress toward adjunctive therapies for #T1D.

📣 Calling all trainees and early-career researchers studying type 1 diabetes #T1D Breakthrough T1D has postdoctoral fellowships and early careers awards for academics and clinician-scientists. 🗓️ Proposals due July 1 International applicants welcome! www.breakthrought1d.org/explore-rese...

What a legacy 🇨🇦 Drs. Till & McCulloch discovered stem cells in the 60s which changed the future of regenerative medicine and contributed to solving one of the biggest hurdles (having enough cells) in the quest to cure type 1 diabetes #T1D #stemcell

A short (12-min) interview about the current and future of islet transplantation. Worth a listen for anyone interested in learning more about cures for #T1D

Yesterday, Health Canada approved the first disease-modifying therapy for type 1 diabetes #T1D. This is a ‘preventative’ (actually ‘delaying’) therapy that addresses autoimmunity *before* someone is diagnosed and requiring insulin. breakthrought1d.ca/news/health-...

Several BreakthroughT1D funding opportunities available 1) Advancing GRS, especially in non-European backgrounds 2) Early detection in adult-onset T1D 3) Tech for scaling manufactured islets Feel free to reach out with questions. Open to industry and academia #funding #grants #T1D

Beyond the Numbers: Real Stories of Navigating Mental Health with type 1 diabetes #T1D. This powerful new video series shares the honest, emotional stories of adults living with type 1 diabetes. 💙 🔗 Watch the series ow.ly/aqb950VKwkL 🔗 Explore mental health & T1D resources ow.ly/J49v50VKwkK

Great new research - one of the difficult aspects of #T1D is that there’s no way to “see” islet or beta cells to check if they are being attacked or functioning well so new biomarkers are important! (More info in comments…)

So much knowledge comes from a registry - this is a catalyst for many other research projects and often helps guide research priorities! If you (or your child) lives with type 1 diabetes #T1D #LADA and are located in Canada 🇨🇦, PLEASE consider contributing to research! (Completely virtual too).

Adult living with #T1D in Edmonton, #Canada…? Consider participating in clinical trials to explore new therapies. Not in Edmonton - look for other actively recruiting trials for type 1 diabetes here clinicaltrials.breakthrought1d.ca/search

www.nature.com/naturecareer... UBC LSI Job!!

VERY important research from the fantastic Dr. Jane Speight. The burden of self-managed chronic conditions should not be underestimated! If you live in Canada and want to find a mental health worker that understands diabetes burden ( #T1D or #T2D) - check on our directory.breakthrought1d.ca

Unfortunate to see today’s news from Vertex about their VX-264 therapy for #T1D but this is why we always have ‘multiple shots on goal’! Considering that the same cells are being used as in VX-880 (so far great data) it’s reasonable to assume that the device encapsulation was the problem here.

Always exciting to see new Clinical Practice Guidelines, but these are especially exciting: - T1D across the lifetime instead of broken up into stages 👏 - recommending AID for all ages and stages of T1D 👏👏 - first in the world to recommend considering the use of adjunctive therapies for T1D 👏👏👏

Really fascinating debate at #ATTD2025 about whether or not we should use placebos in trial design for preventative therapies of #T1D now that Tzield (teplizumab) has shown efficacy and is approved in a few countries. Heavy hitters Colin Dayan and Laura Jacobsen presented excellent points!

This is so powerful… “Has your diabetes been impacted by menopause?” 88% say YES! Research is starting to grow in this area: to see Canadian trials related to menopause and #T1D check out our Clinical Trial Finder clinicaltrials.breakthrought1d.ca

Thrilled to (virtually) watch a fantastic talk at #ATTD2025 from Dr. Cristina Nostro about co-culturing pluripotent stem cells with macrophages which not only provides protection but also increases endocrine output!

www.linkedin.com/posts/emily-... Great post for a very insightful study. IA-2A positive individuals will need close monitoring for #T1D progression!

📣Students and postdocs, consider Canadian universities for grad studies! Tuition is typically offset by teaching assistantships for seminars/labs, and applying is as simple as making contact with a PI to start. If you’re in the field of #T1D - reach out if you’d like us to help make a connection!

Registries are such a critical accelerator for research! If you or someone you know in Canada lives with #T1D, please consider being a part of the BETTER Registry!

I have funding through at least 2031 for postdoctoral researchers with expertise in islet biology or cell-based therapies for, or modelling of, diabetes. Bring your expertise to a country that values it. 🇨🇦 Contact info on my website.

Excellent opportunity for a postdoctoral fellow to join the Breakthrough T1D Centre of Excellence at UBC. International applicants welcome!!!

Early-detection for #T1D is ramping up globally and we have seen the first systemwide (non-research) mandate from Italy for genpop type 1 diabetes screening. To find out what is happening in Canada, check out canscreent1d.ca -> a $12M research consortium funded by Breakthrough T1D and CIHR INMD.

8/ DREAM researcher Dr. Peter Thompson and his lab revealed that #GDF15 is crucial for regulating gene expression during beta cell senescence in #Type1Diabetes, but not for cell survival. Could it be a target for T1D therapies? #BetaCellResearch #CellSenescence pubmed.ncbi.nlm.nih.gov/39196800/

When the days are long or the research hurdles are big, it’s powerful to remember what we are working towards…. (this video expertly created by my colleagues at Breakthrough T1D UK)

Breakthrough T1D Canada has worked very closely with CIHR INMD over the past 6 years to double funding to #T1D research - $60M jointly spent since 2019!! Now they are looking for a new Scientific Director - check it out here if you’re interested! www.cihr-irsc.gc.ca/e/54128.html

Looking forward to reading this! It’s always great to see open-science supporting other researchers too!

Great to see this high impact publication on the use of Semaglutide (Ozempic) in #T1D from a fantastic group of researchers in Montreal. www.nature.com/articles/s41...

Re-upping this paper which is ‘out’ now in this month’s issue of Cell Metab. Working with a fantastic group of collaborators, we provide a resource for exploring human islet variation in health and diabetes. https://www.cell.com/cell-metabolism/fulltext/S1550-4131(24)00365-6

ATTN Canadian and International trainees! The J. Andrew McKee Fellowship is open. Notice of intent is due JAN 30, 2025!! Supported by Breakthrough T1D Canada and Stem Cell Network of Canada, this PDF brings aspiring scientists to the BT1D Centre of Excellence at UBC! t.co/dDWHluBbrX

Exciting results today from Sana Bio. Only n=1 and very preliminary, but fantastic to see allogenic (deceased donor) islet efficacy and safety WITHOUT immunosuppression! It will be fantastic to see this applied to stem cell-derived islets. www.globenewswire.com/news-release...

Breakthrough T1D is committed to supporting emerging trainees in the field of type 1 diabetes. Check out our open funding opportunities: *Clinician Investigator Fellowship *J. Andrew McKee Fellowship in partnership with Stem Cell Network breakthrought1d.ca/research/gra...

I'm excited to join the world of Bluesky to keep in touch with #type1diabetes research and share the work of ongoing projects funded by Breakthrough T1D (formerly JDRF). Follow me to hear about funding opportunities and the work we are doing to support research.